Article
Biochemistry & Molecular Biology
Zanlin Chen, Haiming Li, Miaojia Xie, Fengguang Zhao, Shuangyan Han
Summary: This study presents a label-free aptamer biosensor based on gold nanoparticles/multi-walled carbon nanotubes @ titanium dioxide (AuNPs/MWCNTs@TiO2) for sensitive detection of malachite green (MG). The nanocomposite provides a large surface area and good electrical conductivity, facilitating aptamer immobilization. The detection is achieved by measuring the change in electrical signal resulting from the detachment of aptamer from complementary chain (cDNA) and binding to MG. Under optimal conditions, the sensor demonstrates good linearity and a low limit of detection (LOD).
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Chemistry, Analytical
Dorin Dascalescu, Constantin Apetrei
Summary: This review discusses the recent progress made in the field of electrochemical detection of serotonin using electrochemical sensors based on various nanomaterials, which have excellent analytical performances and practical applications.
Article
Chemistry, Analytical
H. T. Purushothama, Y. Arthoba Nayaka, K. V. Basavarajappa, R. O. Yathisha, P. Manjunatha, M. M. Vinay
Summary: An electrochemical sensor using PR-PGE has been developed for the selective and sensitive determination of Atenolol, with optimized parameters and analytical performance demonstrated in pharmaceutical samples.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Yanbing Chen, Binbin Tao, Xiling Deng, Xiaoqin Wang, Mei Zhang, Yajun Cao, Zhong Wei, Shiguo Sun
Summary: In this study, a binary nanocomposite consisting of nitrogen and sulfur co-doped liquorice carbon (N, S-LC) and functional multiwall carbon nanotubes (f-MWCNTs) was successfully prepared through ultrasonic dispersion technology. The electrochemical performance of the modified electrode showed improved electron transfer ability, and differential pulse voltammetry (DPV) and cyclic voltammetry (CV) were used to investigate the behavior of LicA and LQ. The modified electrode demonstrated satisfactory recoveries in the simultaneous determination of LicA and LQ in licorice.
Article
Engineering, Electrical & Electronic
Rizwan Wahab, Manawwer Alam
Summary: In this study, γ-Al2O3 quantum dots were used as a sensor to detect the organosulfur compound thiourea. The study showed the feasibility and stability of the γ-Al2O3QDs/GCE sensor under different conditions through various experiments and analyses.
SENSORS AND ACTUATORS A-PHYSICAL
(2022)
Article
Chemistry, Physical
Aaliya Qureashi, Altaf Hussain Pandith, Arshid Bashir, Taniya Manzoor, Lateef Ahmad Malik, Faheem A. Sheikh
Summary: The successful surface modification of Fe3O4 nanoparticles with sodium citrate has led to the development of a promising magnetic sorbent material with abundant metal trap centers, showing excellent adsorption capacity for Pb2+ ions. Experimental and theoretical studies confirm the positive impact of surface functionalization on heavy metal ion detection, suggesting its importance in designing absorbent materials. Additionally, the citrate@Fe3O4 nanoparticles exhibit outstanding stability and regeneration over multiple sorption cycles.
SURFACES AND INTERFACES
(2021)
Article
Chemistry, Analytical
Siavash Nazari, Mehdi Shabani-Nooshabadi, Neda Ziaie
Summary: A highly specific electrochemical sensor was developed for the identification and detection of quetiapine (QTPF). The modification of a carbon paste electrode (CPE) with a nanocomposite of iron, lithium ions, and manganese based on nitro-doped carbon enhanced the limit of detection and identification of QTPF. The nanocomposites were characterized using SEM, XRD, and FTIR. The electrochemical behavior of the drug with the modified electrode was studied using cyclic voltammetry, differential pulse voltammetry, chronoamperometry, and EIS. The sensor showed a linear range of 0.090-900 μM and a detection limit of 0.011 μM.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Physical
Muhammad Shafa, Iqbal Ahmad, Shahid Hussain, Muhammad Asif, Yi Pan, Rustem Zairov, Asma A. Alothman, Mohamed Ouladsmane, Zahid Ullah, Nabi Ullah, Chen Lai, Uzma Jabeen
Summary: A nanoalloy-based electrochemical sensor for H2O2 detection has been fabricated using chemical reduction methodology. The prepared samples were characterized by X-ray diffraction and scanning electron microscopy. Among all the compositions, Ag-Cu (9:1) nanoalloys showed the best performance in detecting H2O2.
SURFACES AND INTERFACES
(2023)
Article
Engineering, Electrical & Electronic
Ummama Saeed, Batool Fatima, Dilshad Hussain, Shan E. Zahra Jawad, Muhammad Imran, Muhammad Najam-ul-Haq
Summary: Prostate cancer is a leading cause of mortality, and the PSA test has limitations in its reliability. This study shows that electrochemical sensing using lanthanum tungstate nanoflakes can enhance the accuracy of prostate cancer detection by detecting leucine and valine, which are potential diagnostic biomarkers for prostate cancer.
IEEE SENSORS JOURNAL
(2023)
Article
Chemistry, Analytical
Ghadeer A. R. Y. Suaifan, Mohammad F. Khanfar, Mayadah B. Shehadeh, Asmaa Alnajajrah, Raghad Abuhamdan, Sameer Ahmad Hasan
Summary: This study successfully developed an electroanalytical electrode for the detection of albendazole (ABZ) active ingredient in pharmaceutical dosage form and contaminated animal-derived products. The modified electrode demonstrated high sensitivity and applicability, making it suitable for quality control in the pharmaceutical and food industry.
Article
Chemistry, Multidisciplinary
Aditya Sharma Kalpana, Aditya Sharma Ghrera
Summary: The present study focuses on optimizing the electrochemical deposition parameters for platinum nanoparticles (PtNPs) on the surface of indium-tin-oxide (ITO). These PtNPs were then used to fabricate an immunoelectrode for the detection of the SAA biomarker. The immunoelectrode demonstrated the ability to detect Serum Amyloid A protein (SAA) within a concentration range of 10 fg/ml to 10(6) fg/ml.
Article
Chemistry, Analytical
Vinitha Mariyappan, Naveen Karuppusamy, Shen-Ming Chen, Paulsamy Raja, Rasu Ramachandran
Summary: A WS2/GdCoO3 nanocomposite was successfully prepared using hydrothermal-assisted synthesis, exhibiting excellent performance for detecting quercetin on an electrode. The material showed good electrochemical response and selectivity.
Article
Environmental Sciences
Jih-Hsing Chang, Shan-Yi Shen, Cheng-Di Dong, Mohd Shkir, Mohanraj Kumar
Summary: This study investigates various MoO3 morphologies prepared through different methods for detection of H2O2, finding that morphology significantly affects the properties of MoO3 nanostructures. The modified MoO3/Ni-F electrode shows good performance in electrochemical properties and detection applications.
Review
Chemistry, Analytical
Comnea-Stancu Ionela Raluca, Jacobus (Koos) Frederick van Staden, Raluca-Ioana Stefan-van Staden
Summary: This article provides a summary of the recent developments in electrochemical sensors targeting atrazine. It discusses the use of nanoscale materials as electrode modifiers and compares different analytical parameters. The difficulties and opportunities for developing new sensing technology are also explored.
ANALYTICAL LETTERS
(2022)
Review
Chemistry, Analytical
Comnea-Stancu Ionela Raluca, Jacobus (Koos) Frederick van Staden, Raluca-Ioana Stefan-van Staden
Summary: Atrazine, a persistent herbicide, has various harmful effects and its determination is of great importance. This minireview summarizes the recent developments in electrochemical sensors targeting atrazine, using nanoscale materials as electrode modifiers. Analytical parameters are compiled and compared, and future directions for developing new sensing technology are discussed.
ANALYTICAL LETTERS
(2023)
Article
Chemistry, Analytical
Mahmoud Roushani, Neda Zalpour
Summary: In this study, a new artificial receptor biosensor was successfully designed using a hybrid method of molecularly imprinted polymer and aptamers for ultra-trace Trypsin enzyme recognition. The biosensor showed unparalleled selectivity and sensitivity in real samples, with a good diagnostic linear range and detection limit. The efficiency of the biosensor was significantly improved with the presence of aptamers in the system.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Analytical
Zeinab Rahmati, Mahmoud Roushani, Hadi Hosseini
Summary: In recent years, the combination of aptamers with new nanomaterials has significantly improved the performance of biosensors, particularly in the design of hollow carbon-based materials. This study successfully developed hierarchical porous nickel hydroxide nanosheets on hollow nitrogen-doped carbon nanoboxes, demonstrating sensitive detection of alpha-fetoprotein content.
Article
Biochemistry & Molecular Biology
Masoumeh Nosrati, Mahmoud Roushani
Summary: This study presented a 3D-structural model for a 79-mer ss-DNA aptamer and predicted its binding pocket using molecular docking and dynamics simulation. The results revealed the molecular details of the interaction between streptomycin and aptamer, providing insights for optimizing the aptamer's efficiency in biosensing applications.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Article
Engineering, Electrical & Electronic
Masoumeh Sarabaegi, Mahmoud Roushani, Hadi Hosseini, Zahra Saedi, Ensieh Ghasemian Lemraski
Summary: A specific and sensitive aptasensor for Helicobacter pylori (H. pylori) was designed using a modified electrode with a nano-sized bimetallic NiCo-metal-organic frameworks nanostructure (NiCo-MOF@C) as platform. Due to hydrogen bonds, a large amount of aptamer strands could bind to NiCo-MOF@C, resulting in a detection limit of 1 CFU.ml-1 and a linear range of 101-107 CFU.ml-1. The proposed aptamer-based biosensor showed specificity, low detection limit, extended linear detection range, and stability for H. pylori.
MATERIALS SCIENCE IN SEMICONDUCTOR PROCESSING
(2022)
Article
Chemistry, Analytical
Mahmoud Roushani, Somayeh Farokhi, Zeinab Rahmati
Summary: In this study, a new biological biodevice for the accurate and cost-effective measurement of aflatoxin B1 (AFB1) was proposed. The device is based on a hybrid of molecular imprinting polymer (MIP) and aptamer (Apt) on a glassy carbon electrode modified by Cu2O nanocubes (Cu2O NCs/GCE). The device exhibited high performance, with a linear range of 50.0 pg L-1 to 3.5 ng L-1 and a detection limit of 3.5 ng L-1 to 40.0 ng L-1 and 12.0 pg L-1. The advantages of the device include novelty, high selectivity, portability, and cost-effectiveness.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Analytical
Zeinab Rahmati, Mahmoud Roushani
Summary: A dual recognition biosensor was developed for the selective detection of intact SARS-CoV-2 virus using aptamer strings and molecular imprinting polymer on a screen printed carbon electrode. The biosensor showed a linear relationship between charge transfer resistance and virus concentration, with a low detection limit and short response time.
Article
Chemistry, Analytical
Zahra Mirzaei Karazan, Mahmoud Roushani
Summary: This study introduces an easy detection method for Hippuric Acid (HA) using electrochemical polymerization technique. The sensor exhibited good sensitivity and a wide linear range for HA detection, and it was successfully applied to determine HA in real samples.
Article
Chemistry, Multidisciplinary
Mahmoud Roushani, Alireza Veysi, Hossein Najafi
Summary: The inhibiting effect of adenine on the corrosion of 304 and 316 stainless steels in hydrochloric acid solution was studied. The results showed that the addition of adenine significantly reduced the corrosion rate of the stainless steels, with good inhibiting efficiency. Surface characterization and electrochemical methods revealed that adenine could form a protective film on the surface of the stainless steels, providing corrosion protection.
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Analytical
Neda Zalpour, Mahmoud Roushani, Hadi Hosseini
Summary: This study introduces an innovative method to detect trace amounts of PGB using a combination of powerful MOF structures and the MIP technique. The sensor exhibits high selectivity and reproducibility, showcasing its potential for practical applications.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Engineering, Electrical & Electronic
Zeinab Rahmati, Mahmoud Roushani, Hadi Hosseini
Summary: Preparation of hierarchical nanostructures based on MOFs-derived TMPs has attracted much attention for its attractive properties in electrochemical sensors, particularly in cortisol detection. In this research, a label-free and ultrasensitive electrochemical aptasensor using MOF-derived Ni-P nanorods was developed. The designed aptasensor exhibited a wide linear sensing range between Rct and increasing cortisol concentration, with a low detection limit of 10 aM. The efficiency of the aptasensor was evaluated using real urine samples and compared with the ELISA method, showing satisfactory results.
IEEE SENSORS JOURNAL
(2023)
Article
Chemistry, Analytical
Somayeh Farokhi, Mahmoud Roushani
Summary: Flower-like core-shell nanostructures based on natural asphalt (NA) coated with nickel-layered double hydroxide nanosheets (Ni-LDH NSs) were synthesized for the first time and used as an efficient platform in the design of sarcosine (SAR) electrochemical aptasensor for prostate cancer (PCa) diagnosis. The presented SAR aptasensor showed a promising performance with a linear concentration range and a low limit of detection (LOD). This study can contribute to the development of PCa diagnostic aptasensors and the exploration of NA nanostructures in other electrochemical applications.
Article
Biochemistry & Molecular Biology
Nagham Mahdi, Mahmoud Roushani, Zahra Mirzaei Karazan
Summary: This research developed a sensor based on molecularly imprinted polymer (MIP) for the precise detection of riboflavin (RF), dopamine (DA), and L-tryptophan (Trp) using the electropolymerization method. The MIP/GCE sensor exhibited good selectivity, reproducibility, and stability. It successfully detected RF, DA, and Trp in serum and milk samples with satisfactory results.
JOURNAL OF MOLECULAR RECOGNITION
(2023)
Article
Chemistry, Analytical
Neda Zalpour, Mahmoud Roushani
Summary: One of the cutting-edge emerging approaches in sensors research is the design of flexible, portable, selective sensors that can quickly and accurately identify trace quantities of target molecules. In this study, carbon cloth was used as a binder-free 3D flexible material for the working electrode, and AuCD nanoparticles were synthesized and used to modify the carbon cloth surface. The molecular imprinting polymer approach was utilized to fabricate an imprinted sensor. The optimized sensor exhibited excellent performance in accurately identifying the target molecule.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Somayeh Farokhi, Mahmoud Roushani, Zahra Saedi
Summary: This study reports a new electrochemical strategy for selective and accurate detection of SRN in urine samples. The use of CuCo2O4 nanosheets as a platform improves the diagnostic performance of the electrochemical aptasensor.
ANALYTICAL METHODS
(2023)
Article
Chemistry, Multidisciplinary
Somayeh Farokhi, Mahmoud Roushani, Hadi Hosseini
Summary: In this paper, NiCo-X (X = OH, S, P, Se) nanodiscs were synthesized through hydrothermal method and subsequent treatments. The electrocatalytic performance of these nanodiscs in the determination of isoprenaline (IP) was compared. The results showed that NiCo-Se NDs exhibited better electrocatalytic activity and were successfully used for measuring IP in human blood serum samples.
NEW JOURNAL OF CHEMISTRY
(2022)
