Article
Engineering, Chemical
Yihe Sui, David Wollan, Jacqui McRae, Richard Muhlack, Jonathan Tuke, Kerry Wilkinson
Summary: This study demonstrates the effectiveness of ultrafiltration (UF) in removing astringent compounds from wines, resulting in clarified and stabilized permeate with reduced negative impacts from excess phenolics and proteins.
SEPARATION AND PURIFICATION TECHNOLOGY
(2022)
Article
Chemistry, Analytical
Maria Antonieta P. A. Santiago, Jeancarlo Pereira dos Anjos, Madson M. Nascimento, Gisele O. da Rocha, Jailson B. de Andrade
Summary: The study developed a sample preparation method for multiple pesticides in red and rose wines using binary solvent liquid phase microextraction, demonstrating good linearity and precision values, enabling the detection and quantification of low levels of pesticide residues.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Applied
Bekzod Khakimov, Inal Bakhytkyzy, Carsten Fauhl-Hassek, Soren Balling Engelsen
Summary: The study developed and applied a GC-MS method for molecular fingerprinting of commercial single grape white wines, showing significant metabolic variations between different grape varieties. Classification models based on partial least squares-discriminant analysis demonstrated high certainty for grape variety authentication in an independent test set.
Article
Agricultural Engineering
Hamid Ahadi, Majid Shokrpour, Reza Fatahi, Mohammad Reza Naghavi, Mohammad Hossein Mirjalili
Summary: The metabolic diversity of 24 Iranian Rosa damascena genotypes was studied, and major compounds and phytochemical markers were identified. This study provides valuable information for further commercial cultivation and production of essential oils, flavonoids, and anthocyanins.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Chemistry, Applied
Harischandra R. Naik, M. S. Pallavi, M. Bheemanna, K. PavanKumar, V. Chandra Sekhara Reddy, Udaykumar R. Nidoni, M. Paramasivam, Satish Yadav
Summary: A method for simultaneous determination of 79 pesticide residues in pigeonpea has been developed and validated, with low LOD and LOQ, good recoveries, and applicability for routine monitoring purposes.
Article
Chemistry, Applied
Maria Constantinou, Despo Louca-Christodoulou, Agapios Agapiou
Summary: A validated multi-residue method using LC-MS/MS and GC-MS/MS for analyzing various pesticides in raisins was conducted according to DG SANTE guidelines. Results showed the presence of multiple pesticides in conventional samples, while no analyzed pesticides were detected in samples from organic farming. The study highlights the need for official controls on pesticide residues in processed samples, particularly on high consumption dried fruits like raisins.
Article
Food Science & Technology
Shaowen Liu, Aijuan Bai, Le Song, Nan Zou, Yongtao Han, Li Zhou, Chuanshan Yu, Changjun Li, Canping Pan
Summary: A convenient and fast multi-residue method has been developed for the efficient identification and quantification of 72 pesticides in red and white grape wines. The method achieved consistent recoveries and reduced sample matrix compounds. It was successfully used to detect pesticide residues in commercial grape wines.
Article
Chemistry, Analytical
Maciej Tankiewicz, Andrzej Berg
Summary: In this study, an enhanced methodology for the determination of 31 currently used pesticides in food samples was proposed. The method involves the use of QuEChERS coupled with GC-MS/MS, and an additional extract preconcentration step to improve the limits of quantification. The validated procedure has been successfully applied to various fruit and vegetable samples.
MICROCHEMICAL JOURNAL
(2022)
Article
Food Science & Technology
Thanh-Thien Tran-Lam, Minh Quang Bui, Hoa Quynh Nguyen, Yen Hai Dao, Giang Truong Le
Summary: The optimized analytical method proposed in this study effectively measured 656 pesticide residues in rice samples collected in Vietnam, highlighting the serious environmental and health impacts of pesticide applications. The results demonstrated the efficacy of the method in detecting pesticide contamination in rice and suggested the need for effective management strategies to address these issues.
Article
Chemistry, Applied
Berta Baca-Bocanegra, Leticia Martinez-Lapuente, Julio Nogales-Bueno, Jose Miguel Hernandez-Hierro, Raill Ferrer-Gallego
Summary: Polysaccharides play a critical role in stabilizing and modifying the properties of wines. This study evaluates the use of Fourier transform infrared spectroscopy (FTIR) as a fast and non-destructive method for determining wine polysaccharides. The developed models show the potential of FTIR analysis for routine screening of different types of polysaccharides in wine samples.
CARBOHYDRATE POLYMERS
(2022)
Article
Food Science & Technology
Giacomo Petretto, Pietro Paolo Urgeghe, Roberto Cabizza, Alessandra Del Caro
Summary: This study investigated the chemical-physical and volatile profile of sherry-like white wines with different aging time from three different areas of Sardinia. Proximate chemical composition, CIELab color coordinates and absorbances at 280 and 420 nm were determined. Volatile compounds were determined by solid-phase microextraction (SPME) followed by gas chromatography coupled with a mass spectrometer (GC/MS) using a targeted and untargeted approach. Significant correlations among the age of the wine and most of the chemical physical parameters, such as alcohol content, total acidity, volatile acidity, glycerol and polyphenols were observed. A(280) and A(420) values were highest, as expected, in the oldest wines as well as an increase of a* low values for L* were found during aging. Fifty-nine volatile compounds were identified, among which ethyl acetate, amyl/iso-amyl alcohol, ethyl octanoate, benzaldehyde, ethyl decanoate and phenylethyl alcohol were predominant. The untargeted approach was able to discriminate wines according to their production area, and within each group, according to the year of production.
EUROPEAN FOOD RESEARCH AND TECHNOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Cuicui Ma, Dandan Wei, Pengling Liu, Keliang Fan, Luting Nie, Yu Song, Mian Wang, Lulu Wang, Qingqing Xu, Juan Wang, Jiayu Shi, Jintian Geng, Mengzhen Zhao, Zexin Jia, Changsheng Huan, Wenqian Huo, Chongjian Wang, Zhenxing Mao, Shan Huang, Xin Zeng
Summary: This study evaluated the levels of pesticide residues in commonly consumed vegetables in different regions of Henan Province, China. The results showed that higher detection rates and more types of pesticides were found in rural areas compared to urban areas. Additionally, there were higher detection rates in Eastern Henan.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Food Science & Technology
Qianqian Li, Jialin Zhang, Tao Lin, Chunlin Fan, Yi Li, Zijuan Zhang, Jianxun Li
Summary: The honeysuckle, appreciated for its biological activities, unique aroma and flavor, needs to be explored for potential risks of pesticide residues in order to ensure food safety. The study employed QuEChERS, HPLC-MS/MS, and GC-MS/MS methods to determine pesticide residues in honeysuckle samples. Results showed that 86.02% of the samples were contaminated by at least one pesticide, including the banned pesticide carbofuran. The study also assessed the migration behavior and dietary exposure risk, indicating low risk for human health but identifying five high-risk pesticides. This study provides a foundation for risk assessment of honeysuckle and similar products.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Food Science & Technology
Konstantinos M. M. Kasiotis, Effrosyni Zafeiraki, Electra Manea-Karga, Pelagia Anastasiadou, Kyriaki Machera
Summary: Bees are exposed to environmental contaminants during foraging, resulting in the transfer of pollutants to beehive products. A study analyzed 109 samples of honey, pollen, and beebread, and found various pesticide residues. Despite the presence of pesticide residues, the risk assessment for human and bee health is not a major concern.
Article
Agriculture, Multidisciplinary
Justine Garbay, Margaux Cameleyre, Laurent Riquier, Jean-Christophe Barbe, Georgia Lytra
Summary: An analytical method was developed and optimized to determine the concentrations of aroma compounds related to the fruity aroma of red wines. Samples from different grape varieties were quantitatively analyzed, and the instrumental analysis revealed variations in the concentrations of quantified compounds among the wines. Both sensory profile results and instrumental analysis showed the potential positive contribution of non-ester compounds to the fruity expression of red wines.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Valmore Henrique Pereira dos Santos, Jaine Honorata Hortolan Luiz, Jeancarlo Pereira dos Anjos, Eliane de Oliveira Silva
Summary: Biotransformation is a method for performing uncommon chemical reactions under ecofriendly conditions, and endophytic fungi can produce diverse compounds through metabolism and obtain new steroidal derivatives from underexplored habitats.
Review
Instruments & Instrumentation
Sergio L. C. Ferreira, Ravena S. A. Azevedo, Jucelino B. da Silva Jr, Leonardo S. G. Teixeira, Ivanice. F. F. dos Santos, Walter N. L. dos Santos, Antonio F. S. Queiroz, Olivia M. C. de Oliveira, Lilian L. N. Guarieiro, Jeancarlo P. dos Anjos, Maria V. B. Zanoni, Ricardo B. da Silva, Carla Palma, Vanessa Morgado, Victor Cerda, Vanessa Hatje, Rodrigo M. A. Pedreira
Summary: This review discusses the sources, adverse effects, and quantification of emerging contaminants, including chemical elements used in medicine, microplastics in water bodies, and pharmaceuticals, illicit drugs, and their metabolites in wastewater and sewage sludge. It also addresses the pollution caused by these contaminants in urban areas. The main analytical methods for determining these contaminants are briefly reported.
APPLIED SPECTROSCOPY REVIEWS
(2023)
Article
Biochemistry & Molecular Biology
Thiago Dantas Teixeira, Bruna Aparecida Souza Machado, Gabriele de Abreu Barreto, Jeancarlo Pereira dos Anjos, Ingrid Lessa Leal, Renata Quartieri Nascimento, Katharine Valeria Saraiva Hodel, Marcelo Andres Umsza-Guez
Summary: This study aimed to investigate the impact of low and high-pressure extractions on green propolis and determine the antioxidant profile in the extracts using sonication as a pretreatment. The total flavonoid content, total phenolic compounds, and antioxidant capacity of the twelve green propolis extracts were measured. Results showed higher levels of formononetin and p-coumaric acid in green propolis.
Review
Environmental Sciences
Natalia Menezes, Igor Cruz, Gisele O. da Rocha, Jailson B. de Andrade, Zelinda M. A. N. Leao
Summary: This study investigates the impact of petroleum exploitation and oil spills on coral reefs in marine ecosystems through a systematic review and bibliometric analysis. The main matrices studied are sediments, corals, and water, while air and other invertebrates have been less studied. Recommendations for future research include improving the detection capability of non-conventional PAHs, conducting more studies in underexplored regions in developing countries, and establishing databases to facilitate management planning.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Multidisciplinary Sciences
Fabio N. dos Santos, Madson M. Nascimento, Gisele O. da Rocha, Jailson B. de Andrade
Summary: We used MALDI-MS to investigate if pristine and functionalized fullerenes could be constituents of atmospheric aerosols. We identified several fullerene species, including C-60 and C-70, using matrix laser desorption ionization. The presence of these fullerenes as original constituents of atmospheric particles suggests their potential role in atmospheric chemistry and toxicity studies.
SCIENTIFIC REPORTS
(2023)
Review
Food Science & Technology
Vitor Moreira Rocha, Ricardo Dias Portela, Jeancarlo Pereira dos Anjos, Carolina Oliveira de Souza, Marcelo Andres Umsza-Guez
Summary: Meliponiculture, the breeding of stingless bees, is globally practiced and has a historical connection to early human communities in the Americas. The propolis produced by these bees, a resinous material, holds industrial interest due to its variability and potential applications in food, cosmetics, and pharmaceuticals. The primary focus is on the phenolic compounds in propolis, which have antimicrobial and antioxidant properties. While propolis from stingless bees is mostly recognized for its antioxidant potential, further studies can explore its potential in other sectors, similar to the propolis produced by Apis mellifera. This research presents the composition and biological activities of stingless bee propolis, as well as its potential applications in the food industry.
FOOD PRODUCTION PROCESSING AND NUTRITION
(2023)
Article
Biochemical Research Methods
Pedro Victor Bomfim Bahia, Valdiria Almeida de Oliveira, Madson Moreira Nascimento, Leila Oliveira Santos, Gisele Olimpio da Rocha, Jailson Bittencourt de Andrade, Maria Elisabete Machado
Summary: This study presents the optimization and validation of a microscale extraction procedure for the determination of PANHs in PM2.5 samples, and it demonstrates low limits of detection and quantification as well as accurate and precise results. Additionally, the method is evaluated to be environmentally friendly and scored high in terms of greenness.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Biochemical Research Methods
Madson Moreira Nascimento, Melise Lemos Nascimento, Jeancarlo Pereira dos Anjos, Ricardo Leal Cunha, Gisele Olimpio da Rocha, Ivanice Ferreira dos Santos, Pedro Afonso de Paula Pereira, Jailson Bittencourt de Andrade
Summary: Liquid-phase microextraction (LPME) is a simple, low-cost, and eco-friendly technique used to detect trace concentrations of organic contaminants in water samples. In this study, a novel customized micro-extraction device was developed for the extraction and preconcentration of illicit drugs in surface water and wastewater samples. The method was applied to real samples collected in Brazil, and the main drug detected and quantified was cocaine. The proposed method was considered environmentally friendly according to the AGREE metrics.
JOURNAL OF CHROMATOGRAPHY A
(2023)
Article
Environmental Sciences
Pedro Victor Bomfim Bahia, Madson Moreira Nascimento, Gisele Olimpio da Rocha, Jailson Bittencourt de Andrade, Maria Elisabete Machado
Summary: A green microscale solid-liquid extraction method was developed and applied for the analysis of 23 polycyclic aromatic sulfur heterocycles (PASHs) in PM2.5 samples. The optimal extraction conditions were determined through experimental design and successfully applied to samples collected from different time intervals and sulfur contents in diesel. The reduction of sulfur content in diesel showed a significant impact on the concentration of PASHs.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Chemistry, Multidisciplinary
Madson Moreira Nascimento, Sabrina Teixeira Martinez, Maria Elisabete Machado, Gisele Olimpio da Rocha, Jailson Bittencourt de Andrade
Summary: Baia de Todos os Santos (BTS) is the second-largest Brazilian bay and an important oil producing region in Brazil. This study presents recent research on contamination by polycyclic aromatic compounds (PACs) and Hg in the BTS region, focusing on sediments, water, and biota. The study also discusses the presence of different types of PACs, such as PAHs, nitro-PAHs, oxy-PAHs, and PASHs, as well as the distribution of Hg in seawater, sediments, and biota. The findings on biomonitoring organisms, including polychaetes, ascidians, and corals, are also discussed. The study concludes with suggestions for future research.
Article
Chemistry, Multidisciplinary
Marinice S. S. Acacio, Eliete C. Alves, Jailson B. de Andrade, Jeancarlo P. dos Anjos
Summary: Carbonyl compounds can be formed during craft beer production process, affecting sensory properties and posing a risk to health due to their toxicity. This study quantified 15 carbonyl compounds in craft beers, both in free and bound forms, using hydrolysis and derivatization reactions. The presence of acrolein, benzaldehyde, heptanal, and formaldehyde in craft beers suggests potential undesirable flavors. Frequent consumption of craft beers containing these carbonyl compounds could be harmful to health.
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Multidisciplinary
Marcio Costa Pinto da Siva, Edna dos Santos Almeida, Erika Durao Vieira, Jeancarlo Pereira dos Anjos, Ana Verena Pimentel
Summary: This study evaluated the production of the biosurfactant surfactin using residual oily sludge as a substrate and found that the highest surfactin production was achieved with a substrate containing 3% glucose and 6% oily sludge.
REVISTA VIRTUAL DE QUIMICA
(2023)
Review
Chemistry, Multidisciplinary
Lilian L. N. Guarieiro, Jeancarlo P. dos Anjos, Luciana A. da Silva, Alex A. B. Santos, Ewerton E. S. Calixto, Fernando L. P. Pessoa, Jose L. G. de Almeida, Miguel Andrade Filho, Flavio S. Marinho, Gisele O. da Rocha, Jailson B. de Andrade
Summary: This study provides an overview of the current status of hydrogen production and application, regulation in the green hydrogen sector, storage, distribution, and transportation, as well as the potential economic and environmental impacts and the main challenges and opportunities it represents for the Chemical Sciences.
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Analytical
Michel Rocha Baqueta, Augusto Cesar Costa-Santos, Ana Paula Rebellato, Gisele Marcondes Luz, Juliana Azevedo Lima Pallone, Federico Marini, Alexsandro Lara Teixeira, Douglas N. Rutledge, Patricia Valderrama
Summary: This study reports the essential element composition of new Brazilian Canephora coffees and applies chemometric tools for analysis. The results demonstrate the suitability of this method for origin and species discrimination based on the inorganic fraction of coffee.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Mengjie Li, Jiapeng Wang, You Zhou, Yang Chen, Lingying Xia
Summary: A novel photoelectrochemical biosensor based on gold nanoparticles and specific structures was developed for highly sensitive detection of mercury ion. The multiple sandwich structures hindered electron supply and light harvesting, resulting in a weakened PEC signal, while the specific structures extinguished the PEC signal, enabling quantitative detection of Hg2+. The sensor exhibited high selectivity and stability, with potential applications in environmental detection, biological analysis, and medical research.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Mohamed A. Korany, Rasha M. Youssef, Marwa A. A. Ragab, Mostafa A. Afify
Summary: A stability-indicating fit-for-purpose method was developed for the determination of HC, TL, and PS in syrup dosage form. The method successfully separated CL from THY and quantified the analytes using HPLC-DAD. The robustness of the method was assessed through statistical analysis and self-validation.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Lingling Lin, Minyu Li, Ping Li, Chenqing Ye, Huanglong Zhuang, Shaohuang Weng, Feng Chen
Summary: This study developed a highly sensitive and selective electrochemical sensor for simultaneous detection of dopamine and uric acid. The sensor exhibited excellent anti-interference and stability, and could accurately measure dopamine and uric acid in human urine samples.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Peifang Chen, Caiyun Jiang, Zhouping Wang, Hong-zhen Lian, Xiaoyuan Ma
Summary: In this study, a high-performance SERS-active aptasensor was successfully developed for the quantitative analysis of AFB1 in cereal grains, which is of great significance in the field of food safety.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
E. Abas, C. Marina-Montes, C. Perez-Marin, J. Puimedon, J. Anzano
Summary: This study conducted a comprehensive measurement of natural and anthropogenic radionuclides in soil, water, and air in different locations around Deception Island in Antarctica. The results revealed significant levels of 210Pb and anthropogenic 137Cs in soil samples near old human settlements and facilities, as well as detectable levels of 137Cs and 60Co in water samples from old hunting areas. The findings also suggested potential resuspension processes based on higher-than-expected air quality results.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Joao Franciso Allochio, Nayara A. dos Santos, Nathalia dos S. Conceicao, Clara S. D. Baptista, Keyller B. Borges, Valdemar Lacerda Jr, Wanderson Roma
Summary: This study developed a fiber spray ionization mass spectrometry (FSI-MS) method, which shows great potential in detecting illicit drugs. Compared with paper spray ionization mass spectrometry (PSI-MS), FSI-MS demonstrates higher sensitivity in COC detection.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Dina A. Ahmed, Ola G. Hussein, Mamdouh R. Rezk, Mohamed Abdelkawy, Yasmin Rostom
Summary: The main goal of this study was to develop two green chromatographic techniques, HPLC and TLC, for the determination of alcaftadine (ALF) in pharmaceutical formulation and biological samples. The developed HPLC technique showed high efficiency and minimal environmental impact, successfully identifying ALF in the presence of its degradate. The TLC method provided a stability indicating study for ALF and was determined to be safe, green, and eco-friendly.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Abdullah Taner Bisgin
Summary: A green, speedy, and handy method for separation and determination of four commonly used food colorants was established using vortex assisted sequential-simultaneous liquid phase micro-extraction (VA-SS-LPME). The method does not require any instrumental chromatographic techniques. The procedure includes sequential separation steps using different extractants and simultaneous UV-vis spectrophotometric determination steps. The method is environmentally friendly and applicable for determination of colorants in food and pharmaceuticals.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Yifan Zhang, Tong Zhang, Wenjing Ba, Li Liu, Yuan Rao, Xiaodan Zhang, Hanhan Zhang, Xiu Jin
Summary: This paper proposes a novel spectral transfer modelling method based on neural network architecture searching for the asymptomatic prediction of Akizuki pear cork spot disorder. The experiments show that the model by this method is more effective, achieving an accuracy of 82.61%.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Krzysztof Greda, Maja Welna, Anna Szymczycha-Madeja, Pawel Pohl
Summary: For the first time, a dispersive micro-solid phase extraction (D-mu SPE) based on graphene oxide was used for the ultrasensitive determination of Cd. With this method, Cd can be efficiently extracted from a mixture of alkali and alkaline earth metals without the need for an elution step. The combination of D-mu SPE and SAGD OES significantly reduces matrix effects and improves the tolerance of Cd to alkali metals. The method shows simplicity in the measurement system and the commercially available nanosorbent used.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
P. K. Fathima Anjila, G. R. Tharani, Anand Sundaramoorthy, Venkat Kumar Shanmugam, Karthikeyan Subramani, Shanmugavel Chinnathambi, Ganesh N. Pandian, Vimala Raghavan, Andrews Nirmala Grace, Singaravelu Ganesan, Mangaiyarkarasi Rajendiran
Summary: This work proposes a rapid and sensitive spectroscopic method for detecting melamine in food products using rare-earth Terbium-doped Graphene Quantum Dots (Tb-GQDs) synthesized by microwave and simple chemical conjugation methods. The synthesized Tb-GQDs show a spherical shape with a size of approximately 6 nm and a quantum yield of 52%. The maximum detection limit for melamine concentration in milk and milk products is found to be 0.31 μM. The dual emitting Tb-GQDs provide a sensitive and effective platform for real-time detection of melamine in food samples, particularly in milk, and show promising potential in the food industry.
MICROCHEMICAL JOURNAL
(2024)
Review
Chemistry, Analytical
Piyush Dey, Mandeep Kaur, Akhil Khajuria, Dilmeet Kaur, Manpreet Singh, Hema Kumari Alajangi, Neha Singla, Gurpal Singh, Ravi Pratap Barnwal
Summary: Environmental issues, such as the uncontrolled release of dangerous pollutants, have significant impacts on human health. Traditional methods for detecting pollutants require specialized personnel and equipment, but nanotechnology has improved the performance of biosensors. This article discusses the use of nanotechnology in pollutant detection and the associated techniques.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Sa Dong, Qiuyun Shi, Lingjun Guan, Yulong Wang, Pengyan Liu, Cunzheng Zhang, Jianguo Feng
Summary: In this study, a highly sensitive indirect competitive chemiluminescence enzyme immunoassay (icCLEIA) method was developed for the determination of sodium pentachlorophenolate (PCP-Na) and its metabolite pentachlorophenol (PCP). The method showed high specificity and affinity with a detection limit of 0.0032 ng/mL for PCP-Na and 0.0192 ng/mL for PCP. The method had no cross reaction with other chlorophenols compounds except for PCP. The average recoveries in chicken, pork and fish samples were 81.3-105.8% with low coefficient of variation (CV).
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Palaniappan Ilayaraja, Murugan Manivannan, Paramasivam Parthiban
Summary: Nirmatrelvir, an antiviral drug used for the treatment of COVID-19, has been recommended by the World Health Organization. We developed an optimized analytical method for the quantification of Nirmatrelvir and its products, with high sensitivity and a wide linear range. The method also meets the requirements for greenness evaluation.
MICROCHEMICAL JOURNAL
(2024)