Article
Microbiology
Ranjith Konduri, Chinthala Reddy Saiabhilash, Sisinthy Shivaji
Summary: The study revealed that Staphylococcus aureus and Staphylococcus epidermidis isolated from patients with Endophthalmitis have the potential to form biofilms, with faster formation on corneas and dispersal phase occurring within 48 hours. Biofilm formation renders the bacteria several-fold more resistant to antibiotics compared to planktonic cells.
Article
Biochemistry & Molecular Biology
Denis Swolana, Malgorzata Kepa, Celina Kruszniewska-Rajs, Robert D. Wojtyczka
Summary: Nanosilver has an impact on biofilm formation, gene expression, and viability of Staphylococcus epidermidis. Low concentrations of nanosilver may increase biofilm production, while high concentrations do not have this effect.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Infectious Diseases
Bingjie Wang, Qing Zhan, Yanghua Xiao, Yanlei Xu, Huilin Zhao, Lulin Rao, Xinyi Wang, Jiao Zhang, Li Shen, Ying Zhou, Yinjuan Guo, Xiaocui Wu, Jingyi Yu, Fangyou Yu
Summary: Mupirocin stimulates the biofilm formation of Staphylococcus epidermidis by accelerating autolysis and eDNA release, depending on the specific gene atlE.
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
(2023)
Article
Biochemistry & Molecular Biology
Andrej Minich, Zdenko Levarski, Maria Mikulasova, Marek Straka, Adriana Liptakova, Stanislav Stuchlik
Summary: The study showed that natural phenolic compounds vanillin and syringic acid have similar biofilm and extracellular polymer substance (EPS) inhibition effects on different genotypes of methicillin-resistant S. epidermidis strains. They effectively reduce biofilm formation and EPS content, making them potential inhibitors of biofilms.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Microbiology
Tao Li, Yan Lu, Hua Zhang, Lei Wang, Ross C. Beier, Yajie Jin, Wenjing Wang, Huanrong Li, Xiaolin Hou
Summary: Aloe-emodin demonstrates promising antimicrobial activity against Gram-positive bacteria, particularly Staphylococcus epidermidis. Its mechanism of action involves disrupting cell morphology and selective membrane permeability, affecting protein synthesis and biofilm formation.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Microbiology
Yixin Jin, Qichen Wang, Haomin Zhang, Na Zhao, Ziyu Yang, Hua Wang, Min Li, Qian Liu
Summary: Staphylococcus epidermidis, a human commensal, can form biofilm and cause invasive infections. Our study found that S. epidermidis isolates from different infection sites exhibited different biofilm forming capacity. Isolates from sterile body fluid showed thicker biofilm and expressed higher levels of accumulation-associated protein. The increased expression of certain proteins may contribute to the dispersal of bacteria from biofilm and subsequent spread.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Biochemical Research Methods
Chisato Takahashi, Mari Sato, Chikara Sato
Summary: Staphylococcus epidermidis, a gram-positive bacterium, plays an important role in biofilm formation and microvesicle secretion. This study successfully imaged the microvesicles secreted by Staphylococcus epidermidis and their integration into biofilms using atmospheric scanning electron microscopy (ASEM). The information obtained is expected to help elucidate the biological mechanism of biofilm formation and develop medicines against biofilms and associated infections.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2021)
Article
Microbiology
Shihua Lan, Xiaofeng Chen, Chuanping Yin, Shengjun Xie, Shuaishuai Wang, Rongrong Deng, Zhibin Shen
Summary: Research found that Disaspidin BB obtained from plant extracts and purifications has inhibitory effect on drug-resistant Staphylococcus epidermidis biofilms, and its mechanism of anti-biofilm activity was preliminarily investigated.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Cell Biology
Kidon Sung, Miseon Park, Jungwhan Chon, Ohgew Kweon, Saeed A. Khan, Andrew Shen, Angel Paredes
Summary: This study investigates the effect of subinhibitory concentrations of tigecycline on biofilms formed by Staphylococcus epidermidis strain RP62A. The results show that different concentrations of tigecycline can cause changes in biofilm production and significantly affect protein expression. The study suggests that analyzing the global protein expression profile of biofilm cells under antibiotic pressure can improve our understanding of the mechanisms of antibiotic resistance.
Article
Microbiology
Yongqi Mu, Hong Zeng, Wei Chen
Summary: Quercetin exhibits anti-biofilm activity against Staphylococcus epidermidis by reducing cell surface hydrophobicity and inhibiting polysaccharide intercellular adhesin production, indicating its potential as an anti-biofilm agent for biofilm infections caused by S. epidermidis and potentially other bacteria.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Immunology
Susmita Das, Sukhvinder Singh, Ashok Kumar
Summary: The study found that while S. epidermidis is rapidly cleared from mouse eyes, a relatively higher bacterial dose is needed to cause endophthalmitis. Bacterial load peaked at 24 h postinfection and gradually declined, while neutrophil infiltration continued to increase up to 72 h, resulting in significant retinal tissue damage and loss of visual function. In vitro experiments showed that S. epidermidis induced activation of inflammatory signaling pathways and production of cytokines and chemokines in various cell types.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Immunology
Johanna Stamm, Samira Weisselberg, Anna Both, Antonio Virgilio Failla, Gerhard Nordholt, Henning Buettner, Stefan Linder, Martin Aepfelbacher, Holger Rohde
Summary: This study explores the effect of growth media on the biofilm formation of Staphylococcus epidermidis. By utilizing an artificial synovial fluid (ASF) medium that mimics the conditions encountered during host invasion, the researchers found that ASF induces the formation of biofilm and cluster in S. epidermidis. Gene expression analysis also revealed changes in the expression of genes related to adhesion and autolysis. These findings suggest the importance of using growth media that mimic host environments for future studies on the pathogenesis of S. epidermidis prosthetic joint infections.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Immunology
P. Kasparova, E. Vankova, L. Brazdova, K. Lokocova, O. Matatkova, J. Masak
Summary: Pterostilbene (PTE) is a natural compound with antioxidant and antimicrobial properties, which can enhance the effectiveness of erythromycin and tetracycline in inhibiting the growth and biofilm formation of Staphylococcus epidermidis. PTE was found to effectively inhibit S. epidermidis, reduce metabolic activity of biofilm cells, and enhance the action of antibiotics in overcoming biofilm cell tolerance.
MICROBIAL PATHOGENESIS
(2021)
Article
Microbiology
Laurine Kaul, Adrian I. Abdo, Tom Coenye, Bastiaan P. Krom, Michel A. Hoogenkamp, Andrew C. W. Zannettino, Regine Suess, Katharina Richter
Summary: This study describes the antibacterial properties of a combination treatment of diethyldithiocarbamate (DDC) and copper ions (Cu2+), which showed synergistic and additive effects against planktonic and biofilm cultures of Staphylococcus aureus and Staphylococcus epidermidis, with low cytotoxicity.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Immunology
Jiaxue Wang, Lulin Rao, Zhuoan Huang, Lili Ma, Tian Yang, Zhongqi Yu, Aihua Sun, Yumei Ge
Summary: The current study investigates the impact of the nitric oxide synthase (NOS) gene on biofilm formation in Staphylococcus epidermidis (S. epidermidis). The results show that deletion of the NOS gene enhances biofilm formation, slightly retards bacterial growth, decreases autolysis rate, and weakens bacterial biofilm dispersal. Gene expression analysis suggests that the NOS gene negatively regulates biofilm formation by affecting biofilm aggregation and dispersal.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Jose M. Murrieta-Coxca, Ruby N. Gutierrez-Samudio, Heba M. El-Shorafa, Tanja Groten, Sandra Rodriguez-Martinez, Mario E. Cancino-Diaz, Juan C. Cancino-Diaz, Rodolfo R. Favaro, Udo R. Markert, Diana M. Morales-Prieto
Summary: The study demonstrates that IL-36 cytokines are modulated by microbial components and play a role in trophoblast migration and interaction with endothelial cells. These cytokines may have a fundamental role in the placentation process and in response to infections.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Microbiology
Sergio Martinez-Garcia, Humberto Peralta, Gabriel Betanzos-Cabrera, Leslie Chavez-Galan, Sandra Rodriguez-Martinez, Mario E. Cancino-Diaz, Juan C. Cancino-Diaz
Summary: The study found that biofilm-forming bacteria lack TCA cycle proteins, and lactate, formate, and acetoin are end products of partial glucose metabolism in these bacteria. Planktonic cells, on the other hand, have a more diverse metabolic profile including glycolysis, TCA cycle, pentose phosphate pathway, gluconeogenesis, ATP generation, and oxidative stress response.
RESEARCH IN MICROBIOLOGY
(2021)
Article
Immunology
Miguel A. De la Rosa-Ramos, Roberto Salcedo-Hernandez, Rosa E. Sarmiento-Silva, Ma G. Aguilera-Arreola, Maria D. Alcantar-Curiel, Gabriel Betanzos-Cabrera, Sandra Rodriguez-Martinez, Mario E. Cancino-Diaz, Juan C. Cancino-Diaz
Summary: The study found that supernatants of non-epidermidis CoNS from different animals have hemagglutination inhibition activity against Newcastle disease virus and bovine parainfluenza virus type 3, indicating that not only S. epidermidis, other CoNS species also have similar functions.
COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES
(2021)
Article
Biotechnology & Applied Microbiology
A. A. Trevino-Trejo, H. A. Alvarez-Hernandez, J. A. Cruz-Maya, J. Jan-Roblero
Summary: The study demonstrates that Amycolatopsis sp. Ver12 can efficiently degrade BbF and has the potential for bioremediation of BbF-contaminated environments.
LETTERS IN APPLIED MICROBIOLOGY
(2021)
Article
Plant Sciences
Enriqueta Amora-Lazcano, Hector J. Quiroz-Gonzalez, Cristofer Osornio-Ortega, Juan A. Cruz-Maya, Janet Jan-Roblero
Summary: This study aimed to investigate the deficiency in sorghum growth in low-nutrient soils and found that adding plant growth-promoting bacteria could overcome this soil deficiency. The results showed that IAA-producing Pseudomonas strains improved sorghum growth in low-nutrient soil, and Pseudomonas sp. BI-1 and P. mohnii BIPS-10 were suggested as potential bioinoculants for sorghum.
BOTANICAL SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Fernando Gomez-Chavez, Carlos Cedillo-Pelaez, Luis A. Zapi-Colin, Guadalupe Gutierrez-Gonzalez, Isai Martinez-Torres, Humberto Peralta, Leslie Chavez-Galan, Erick D. Avila-Calderon, Araceli Contreras-Rodriguez, Yaneth Bartolo-Aguilar, Sandra Rodriguez-Martinez, Mario E. Cancino-Diaz, Juan C. Cancino-Diaz
Summary: The study found that EVs from Staphylococcus epidermidis can modulate cytokine production and inflammation in skin, with different origins of EVs leading to varying effects on the immune environment and cell responses.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Microbiology
Carmen Vargas-Lagunas, Yolanda Mora, Alejandro Aguilar, Alma Ruth Reyes-Gonzalez, Alejandra Arteaga-Ide, Michael F. Dunn, Sergio Encarnacion, Lourdes Girard, Humberto Peralta, Jaime Mora
Summary: Biotin is an essential factor for the growth of rhizobial strains. Some strains lack the ability to synthesize biotin, but growth can be restored through the addition of biotin or genetic complementation. Rhizobial strains also possess genes for biotin transport and an avidin homologue called rhizavidin. In addition, a route of biotin-independent growth involving oxygen, a Tar receptor, and a Rubisco-like protein has been discovered.
Article
Microbiology
Itzia S. Gomez-Alonso, Ilse D. Estrada-Aleman, Sergio Martinez-Garcia, Humberto Peralta, Erika T. Quintana, Claudia Guerrero-Barajas, Cipriano Chavez-Cabrera, Sandra Rodriguez-Martinez, Mario E. Cancino-Diaz, Juan C. Cancino-Diaz
Summary: This study investigated the distribution and expression of sdrG, sdgA, and sdgB genes in S.epidermidis. The results showed that these genes are widely present but their expression is influenced by biofilm-forming conditions.
ARCHIVES OF MICROBIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Isai Martinez-Torres, Araceli Tepale-Segura, Octavio Castro-Escamilla, Juan Carlos Cancino-Diaz, Sandra Rodriguez-Martinez, Sonia Mayra Perez-Tapia, Laura C. Bonifaz, Mario Eugenio Cancino-Diaz
Summary: Psoriasis is a chronic inflammatory skin disease characterized by excessive activation of immune cells and inflammatory cytokines. HIF-1α and pVHL play important roles in regulating angiogenesis and glycolysis, affecting the severity of psoriatic lesions. Restoring pVHL expression can prevent and alleviate psoriasis lesions by inhibiting inflammation and immune cell infiltration.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Itzia S. Gomez-Alonso, Sergio Martinez-Garcia, Gabriel Betanzos-Cabrera, Esmeralda Juarez, Maria C. Sarabia-Leon, Maria Teresa Herrera, Fernando Gomez-Chavez, Luvia Sanchez-Torres, Sandra Rodriguez-Martinez, Mario E. Cancino-Diaz, Jorge Cancino, Juan C. Cancino-Diaz
Summary: Protease-3 released by neutrophils in the presence of commensal non-biofilm-forming S. epidermidis plays a key role in promoting biofilm formation by facilitating cell aggregation through the release of bacterial DNA.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Editorial Material
Biochemistry & Molecular Biology
Carlos Olvera-Sandoval, Hector Enrique Fabela-Illescas, Eduardo Fernandez-Martinez, Maria Araceli Ortiz-Rodriguez, Raquel Carino-Cortes, Jose Alberto Ariza-Ortega, Juan Carlos Hernandez-Gonzalez, Diana Olivo, Carmen Valadez-Vega, Helen Belefant-Miller, Gabriel Betanzos-Cabrera
Summary: Pomegranate is a polyphenol-rich fruit that has various biological activities, including antioxidative, antimicrobial, anti-inflammatory, anticarcinogenic, cardioprotective, and antidiabetic effects. This review focuses on the hypoglycemic effect of pomegranate juice, highlighting its chemical composition and possible mechanisms of action. The results suggest that pomegranate juice can decrease oxidative stress damage, increase insulin-dependent glucose uptake, maintain beta-cell integrity, inhibit protein glycation, improve insulin sensitivity, and modulate various enzymes and receptors related to glucose metabolism.
Article
Food Science & Technology
Carmen Valadez-Vega, Olivia Lugo-Magana, Claudia Figueroa-Hernandez, Mirandeli Bautista, Gabriel Betanzos-Cabrera, Aurea Bernardino-Nicanor, Rosa Maria Gonzalez-Amaro, Rodrigo Alonso-Villegas, Jose A. Morales-Gonzalez, Leopoldo Gonzalez-Cruz
Summary: This study analyzed the composition, nutritional value, and the effect of chemical treatments on the elimination of anti-nutritional compounds in Amaranth seeds. The results showed that germination significantly improved digestibility and reduced lectin concentration, while increasing tannin content.
Article
Biochemistry & Molecular Biology
Cesar G. Pelcastre-Rodriguez, Ernesto A. Vazquez-Sanchez, Jose M. Murrieta-Coxca, Sandra Rodriguez-Martinez, Juan C. Cancino-Diaz, Mario E. Cancino-Diaz
Summary: The study found that IL-36 is involved in the activation of mesangial cells and the production of inflammation, with specific members potentially playing a key role in the inflammation associated with infections in the glomerular environment.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Carmen Valadez-Vega, Olivia Lugo-Magana, Gabriel Betanzos-Cabrera, Jose Roberto Villagomez-Ibarra
Summary: This study purified and partially characterized the lectins of Phaseolus vulgaris black, var surco and vara. The lectins were found to be tetrameric glycoproteins that require calcium, manganese, and magnesium ions for their hemagglutinating function, and have different optimal pH and temperature sensitivity.
Article
Plant Sciences
Jose Antonio Guerrero-Solano, Mirandeli Bautista, Josue Vidal Espinosa-Juarez, Luis Alfonso Moreno-Rocha, Gabriel Betanzos-Cabrera, Liana Claudia Salanta, Minarda De la O. Arciniega, Elena G. Olvera-Hernandez, Osmar Antonio Jaramillo-Morales
Summary: Pharmacological treatment of pain often leads to undesirable effects, so it is important to explore natural, safe, and effective alternatives. Pomegranate has been used as a preventive and therapeutic agent for its antinociceptive effect, and different parts of the fruit display unique pharmacological activities. This study evaluated the antinociceptive effect of pomegranate extracts and juices from three varieties, and found that they had promising pharmacodynamic properties for the treatment of pain.