Article
Clinical Neurology
Kirsten Hall Long, Carin Smith, Ronald Petersen, Jane Emerson, Jeanine Ransom, Michelle M. Mielke, Steven Hass, Cynthia Leibson
Summary: This study examined the cost-effectiveness of managing cognitive impairment in Olmsted County, MN residents aged 70-89 years. Results showed significant differences in cost distributions across cognitive categories, with higher medical and medical + nursing home costs for MCI patients compared to cognitively unimpaired individuals.
ALZHEIMERS & DEMENTIA
(2022)
Article
Geriatrics & Gerontology
Brian Nguyen, William James Deardorff, Ying Shi, Bocheng Jing, Alexandra K. Lee, Sei J. Lee
Summary: NH residents receive frequent fingersticks regardless of level of cognitive impairment, suggesting that cognitive status is a minor consideration in monitoring decisions.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2022)
Article
Geriatrics & Gerontology
John N. Morris, Elizabeth P. Howard, Erez Schachter, Sharran Burney, Anna Laytham, Daniela Fialova, Emiel O. Hoogendijk, Rosa Liperoti, Hein P. J. van Hout Mpsy, Davide Liborio Vetrano
Summary: This study examined cognitive changes among nursing home residents and developed a risk model for predicting cognitive decline. The results showed that residents with milder impairment had higher rates of cognitive decline, and the CogRisk-NH scale was able to predict the risk of cognitive decline.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2023)
Article
Geriatrics & Gerontology
Tadeja Gracner, Patricia W. Stone, Mansi Agarwal, Mark Sorbero, Susan L. Mitchell, Andrew W. Dick
Summary: This study compared mortality risk factors and survival between nursing home residents with advanced Alzheimer's disease and Alzheimer's disease related dementia, revealing distinct patterns of survival and mortality between the two groups.
Article
Psychology, Multidisciplinary
Rosa Silva, Elzbieta Bobrowicz-Campos, Paulo Santos-Costa, Ana Rita Cruz, Joao Apostolo
Summary: The study found that the individual cognitive stimulation program implemented by caregivers showed promising results in improving the cognition of persons with cognitive impairment, but had no significant impact on caregivers' physical and mental health.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Geriatrics & Gerontology
Yiyang Yuan, Kate L. Lapane, Jennifer Tjia, Jonggyu Baek, Shao-Hsien Liu, Christine M. Ulbricht
Summary: The study identified three physical frailty subgroups in older nursing home residents: mild, moderate, and severe. Those with moderate or severe physical frailty were more likely to have cognitive impairment and need assistance in daily activities. The findings suggest a complex interplay between physical frailty and cognitive impairment in this population.
Article
Nursing
Angela M. H. J. Mengelers, Vincent R. A. Moermans, Michel H. C. Bleijlevens, Hilde Verbeek, Elizabeth Capezuti, Frans Tan, Koen Milisen, Jan P. H. Hamers
Summary: This study aimed to investigate the demand, use, and associated factors of involuntary treatment in people with dementia (PwD) receiving professional home care in the Netherlands and Belgium. The findings revealed that more than half of the PwD living at home received involuntary treatment, including nonconsensual care, psychotropic medication, and physical restraints. The use of involuntary treatment was influenced by living status, ADL dependency, cognitive ability, caregiver burden, and the country where home care was received. The study highlights the need for further research on variations in prevalence and the prevention of involuntary treatment in dementia.
JOURNAL OF CLINICAL NURSING
(2022)
Article
Clinical Neurology
Vijay K. Ramanan, Melissa J. Armstrong, Parichita Choudhury, Katherine A. Coerver, Roy H. Hamilton, Brad C. Klein, David A. Wolk, Scott R. Wessels, Lyell K. Jones Jr
Summary: This article provides practical guidance on logistic adaptations and decision making related to emerging antiamyloid mAbs in neurology, including patient selection, treatment monitoring, and communication. It emphasizes the importance of shared decision making, multidisciplinary collaboration, and future development.
Article
Anesthesiology
Zhangjie Jiang, Feng Liang, Yida Zhang, Yuanlin Dong, Annie Song, Xiaoping Zhu, Yiying Zhang, Zhongcong Xie
Summary: This study established a mouse model of urinary catheterization (UC) and found that UC induced delirium-like behavior in mice. UC decreased glucose and energy amounts in the brain, possibly by impairing glucose transport. These findings provide new insights into the etiology and underlying mechanisms of delirium.
ANESTHESIA AND ANALGESIA
(2022)
Review
Behavioral Sciences
Xingyao Tang, Wei Zhao, Ming Lu, Xin Zhang, Ping Zhang, Zhong Xin, Ran Sun, Wei Tian, Marly Augusto Cardoso, Jinkui Yang, Rafael Sim, Jian-Bo Zhou, Coen D. A. Stehouwer
Summary: The study found a higher waist circumference to be associated with an increased risk of cognitive impairment and dementia, especially in individuals over the age of 65.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2021)
Article
Geriatrics & Gerontology
Shuji Tsuda, Hiroshige Matsumoto, Shun Takehara, Tomoyuki Yabuki, Satoko Hotta
Summary: Although people with cognitive impairment value social participation in out-of-home activities, their families often have concerns and anxiety over such activities. This study identified the factors associated with family caregivers' anxiety and found that concerns about behavioral issues were significantly linked to caregiver anxiety. Caregivers' anxiety was also associated with the individual's cognitive function, long-term care status, and engagement in out-of-home activities.
Review
Biochemistry & Molecular Biology
Kyoungjoo Cho
Summary: Cognitive impairment is a serious condition associated with aging and disruption of inflammation and innate immunity. Recent studies have shown that the innate immune system is prevalent in patients with Alzheimer's disease, and peripheral neutrophil markers can predict a decline in cognitive function in patients with mild cognitive impairment. Furthermore, altered levels of pro-inflammatory interleukins have been reported in patients with mild cognitive impairment, potentially playing a role in the progression from early cognitive impairment to dementia.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Gerontology
Emmanuel Sumithran Gnanamanickam, Suzanne Marie Dyer, Stephanie Lucy Harrison, Enwu Liu, Craig Whitehead, Maria Crotty
Summary: This study examined the associations between cognitive function, hospitalizations, and costs in an Australian nursing home population. The findings showed that participants with dementia had fewer hospitalizations and lower hospitalization costs compared to those without dementia. Poorer cognition scores were also associated with reduced hospitalizations. However, the cost per admission was greater for individuals with dementia due to longer hospital stays. Fractures were the most common reason for hospitalization among people with dementia. These findings suggest the need for increased investment in accurate and timely diagnosis of dementia, as well as fall and fracture prevention strategies, to further reduce associated hospitalization costs.
JOURNAL OF AGING & SOCIAL POLICY
(2022)
Article
Nursing
Annamaria Pakai, Emese Havasi-Santha, Erzsebet Mak, Orsolya Mate, Dorina Pusztai, Noemi Fuller, Miklos Zrinyi, Andras Olah
Summary: The study found that cognitive function, self-care capacity, and nurse support can influence the risk of malnutrition in older residents. Older adults with better cognitive function and more independent self-feeding had lower risk of malnutrition. Self-care capacity and appetite were key predictors in predicting malnutrition risk.
Article
Nursing
Trygve J. L. Saevareid, Reidar Pedersen, Lisbeth Thoresen
Summary: The study describes the advance care planning in nursing homes involving residents with cognitive impairment and their next of kin. Challenges identified included vague preferences, lack of medical information, and focus on past and present rather than future end-of-life care. Residents with cognitive impairment can actively participate in advance care planning with the support of healthcare personnel, but there are several challenges that need to be addressed.
JOURNAL OF ADVANCED NURSING
(2021)
Letter
Psychiatry
Seamus V. McNulty, Graham A. Jackson, Anthony J. Pelosi
BRITISH JOURNAL OF PSYCHIATRY
(2008)
Editorial Material
Geriatrics & Gerontology
Debbie Tolson, Belinda Dewar, Graham A. Jackson
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2014)
Article
Gerontology
Wilson Abreu, Debbie Tolson, Graham A. Jackson, Nilza Costa
DEMENTIA-INTERNATIONAL JOURNAL OF SOCIAL RESEARCH AND PRACTICE
(2020)
Review
Gerontology
Elizabeth Hanson, Amanda Hellstrom, Asa Sandvide, Graham A. Jackson, Rhoda MacRae, Anna Waugh, Wilson Abreu, Debbie Tolson
DEMENTIA-INTERNATIONAL JOURNAL OF SOCIAL RESEARCH AND PRACTICE
(2019)
Article
Gerontology
Jacqueline Pearce, Winn Forsyth, Robert Boyd, Graham A. Jackson
DEMENTIA-INTERNATIONAL JOURNAL OF SOCIAL RESEARCH AND PRACTICE
(2012)
Article
Medicine, General & Internal
Anthony J. Pelosi, Seamus V. McNulty, Graham A. Jackson
BMJ-BRITISH MEDICAL JOURNAL
(2006)
Article
Psychiatry
SV McNulty, L Duncan, M Semple, GA Jackson, AJ Pelosi
BRITISH JOURNAL OF PSYCHIATRY
(2003)
Article
Medicine, General & Internal
AJ Pelosi, GA Jackson
BRITISH MEDICAL JOURNAL
(2000)
Letter
Geriatrics & Gerontology
Graham A. Jackson
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
(2007)