Epigenetics, epidemiology and mitochondrial DNA diseases

The epigenomic interface between genome and environment in common complex diseases

(2011) C. G. Bell et al.   Briefings in Functional Genomics

MicroRNA-342 inhibits colorectal cancer cell proliferation and invasion by directly targeting DNA methyltransferase 1

(2011) Hui Wang et al.   CARCINOGENESIS

The Human Mitochondrial Transcriptome

(2011) Tim R. Mercer et al.   CELL

DNA methylation in white blood cells

(2011) Mary Beth Terry et al.   Epigenetics

Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome

(2011) Juan Sandoval et al.   Epigenetics

Global methylation profiles in DNA from different blood cell types

(2011) Hui-Chen Wu et al.   Epigenetics

MicroRNAs and epigenetics

(2011) Fumiaki Sato et al.   FEBS Journal

Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells

(2011) H. Wu et al.   GENES & DEVELOPMENT

High density DNA methylation array with single CpG site resolution

(2011) Marina Bibikova et al.   GENOMICS

Genome-wide survey reveals predisposing diabetes type 2-related DNA methylation variations in human peripheral blood

(2011) Gidon Toperoff et al.   HUMAN MOLECULAR GENETICS

Shot-gun proteomic analysis of mitochondrial D-loop DNA binding proteins: identification of mitochondrial histones

(2011) Yon-Sik Choi et al.   Molecular BioSystems

Identification and Functional Analysis of Epigenetically Silenced MicroRNAs in Colorectal Cancer Cells

(2011) Hongli Yan et al.   PLoS One

DNA methyltransferase 1, cytosine methylation, and cytosine hydroxymethylation in mammalian mitochondria

(2011) Lisa S. Shock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Leber’s Hereditary Optic Neuropathy

(2010) Alfredo A. Sadun et al.   Current Treatment Options in Neurology

Unmasking the causes of multifactorial disorders: OXPHOS differences between mitochondrial haplogroups

(2010) Aurora Gómez-Durán et al.   HUMAN MOLECULAR GENETICS

miRNAs in human cancer

(2010) Thalia A Farazi et al.   JOURNAL OF PATHOLOGY

Early detection of squamous cell lung cancer in sputum by a panel of microRNA markers

(2010) Lingxiao Xing et al.   MODERN PATHOLOGY

Taking the measure of the methylome

(2010) Stephan Beck   NATURE BIOTECHNOLOGY

Quantitative comparison of genome-wide DNA methylation mapping technologies

(2010) Christoph Bock et al.   NATURE BIOTECHNOLOGY

174th ENMC International Workshop: Applying pre-implantation genetic diagnosis to mtDNA diseases: Implications of scientific advances 19–21 March 2010, Naarden, The Netherlands

(2010) J. Poulton et al.   NEUROMUSCULAR DISORDERS

Hypoxia-regulated microRNA-210 modulates mitochondrial function and decreases ISCU and COX10 expression

(2010) Z Chen et al.   ONCOGENE

Parental smoking during pregnancy and offspring bone mass at age 10 years: findings from a prospective birth cohort

(2010) C. Macdonald-Wallis et al.   OSTEOPOROSIS INTERNATIONAL

The Behaviour of 5-Hydroxymethylcytosine in Bisulfite Sequencing

(2010) Yun Huang et al.   PLoS One

Two New Pimelic Diphenylamide HDAC Inhibitors Induce Sustained Frataxin Upregulation in Cells from Friedreich's Ataxia Patients and in a Mouse Model

(2010) Myriam Rai et al.   PLoS One

MicroRNA 128a Increases Intracellular ROS Level by Targeting Bmi-1 and Inhibits Medulloblastoma Cancer Cell Growth by Promoting Senescence

(2010) Sujatha Venkataraman et al.   PLoS One

Bioenergetics, the origins of complexity, and the ascent of man

(2010) D. C. Wallace   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNAs identified in highly purified liver-derived mitochondria may play a role in apoptosis

(2010) Betsy T. Kren et al.   RNA Biology

Zen and the art of mitochondrial DNA maintenance

(2010) Ian J. Holt   TRENDS IN GENETICS

The DNA Methylome of Human Peripheral Blood Mononuclear Cells

(2010) Yingrui Li et al.   PLOS BIOLOGY

miR-30 Regulates Mitochondrial Fission through Targeting p53 and the Dynamin-Related Protein-1 Pathway

(2010) Jincheng Li et al.   PLoS Genetics

Gene–environment interactions in Leber hereditary optic neuropathy

(2009) Matthew Anthony Kirkman et al.   BRAIN

The promises and challenges of epigenetic epidemiology

(2009) Karin B. Michels   EXPERIMENTAL GERONTOLOGY

Human DNA methylomes at base resolution show widespread epigenomic differences

(2009) Ryan Lister et al.   NATURE

Nucleosome positioning and gene regulation: advances through genomics

(2009) Cizhong Jiang et al.   NATURE REVIEWS GENETICS

In vivo methylation of mtDNA reveals the dynamics of protein–mtDNA interactions

(2009) Adriana P. Rebelo et al.   NUCLEIC ACIDS RESEARCH

An Epigenetic Signature in Peripheral Blood Predicts Active Ovarian Cancer

(2009) Andrew E. Teschendorff et al.   PLoS One

Pathogenic Mitochondrial DNA Mutations Are Common in the General Population

(2008) Hannah R. Elliott et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Feeding pregnant rats a protein-restricted diet persistently alters the methylation of specific cytosines in the hepatic PPARα promoter of the offspring

(2008) Karen A. Lillycrop et al.   BRITISH JOURNAL OF NUTRITION

Mitochondrial nucleoids undergo remodeling in response to metabolic cues

(2008) M. Kucej et al.   JOURNAL OF CELL SCIENCE

Genomic DNA hypomethylation as a biomarker for bladder cancer susceptibility in the Spanish Bladder Cancer Study: a case–control study

(2008) Lee E Moore et al.   LANCET ONCOLOGY

The mitochondrial DNA genetic bottleneck results from replication of a subpopulation of genomes

(2008) Timothy Wai et al.   NATURE GENETICS

A reduction of mitochondrial DNA molecules during embryogenesis explains the rapid segregation of genotypes

(2008) Lynsey M Cree et al.   NATURE GENETICS

Evidence for a Novel X-Linked Modifier Locus for Leber Hereditary Optic Neuropathy

(2008) Suma P. Shankar et al.   OPHTHALMIC GENETICS

Real-time PCR quantification of precursor and mature microRNA

(2007) Thomas D. Schmittgen et al.   METHODS