Article
Peripheral Vascular Disease
Angela M. Malek, Kelly J. Hunt, Tanya N. Turan, Julio Mateus, Daniel T. Lackland, Anika Lucas, Dulaney A. Wilson
Summary: This study examined the risk of maternal kidney disease after a hypertensive condition during pregnancy, with consideration of racial/ethnic differences. The results showed that women with hypertensive disorders of pregnancy had a higher risk of developing kidney disease 5 years after delivery, and the risk was higher in non-Hispanic Black women compared to non-Hispanic White women.
Article
Obstetrics & Gynecology
Franca Rusconi, Monia Puglia, Martina Pacifici, Sonia Brescianini, Luigi Gagliardi, Anna Maria Nannavecchia, Pietro Buono, Sara Cantoira, Sara Farchi, Michele Gobbato, Edda Pellegrini, Enrica Perrone, Riccardo Pertile, Elisa Eleonora Tavormina, Laura Visona Dalla Pozza, Francesca Zambri
Summary: There was a decrease in the rate of preterm birth in Italy after the introduction of COVID-19 restriction measures, without an increase in stillbirths.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Caroline Brito Nunes, Peiyuan Huang, Geng Wang, Mischa Lundberg, Shannon D'Urso, Robyn E. Wootton, Maria Carolina Borges, Deborah A. Lawlor, Nicole M. Warrington, David M. Evans, Liang-Dar Hwang, Gunn-Helen Moen
Summary: This study investigated the relationship between coffee consumption and adverse pregnancy outcomes using Mendelian randomization (MR). The results suggest that coffee consumption during pregnancy may not contribute to adverse outcomes such as miscarriage, stillbirth, pre-term birth, lower gestational age, or birthweight of the offspring.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Obstetrics & Gynecology
Lisa Hui, Melvin Barrientos Marzan, Stephanie Potenza, Daniel L. Rolnik, Natasha Pritchard, Joanne M. Said, Kirsten R. Palmer, Clare L. Whitehead, Penelope M. Sheehan, Jolyon Ford, Ben W. Mol, Susan P. Walker
Summary: The lockdown restrictions in Melbourne, Australia were associated with a significant increase in preterm stillbirths among pregnant women exposed to the lockdown, but also led to a significant reduction in iatrogenic preterm births for fetal compromise. Further research is needed to understand the relationship between these two findings and to guide future responses to pandemics.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Stefanie N. Hinkle, Enrique F. Schisterman, Danping Liu, Anna Z. Pollack, Edwina H. Yeung, Sunni L. Mumford, Katherine L. Grantz, Yan Qiao, Neil J. Perkins, James L. Mills, Pauline Mendola, Cuilin Zhang
Summary: This study investigated the association between pregnancy complications and total and cause-specific mortality, as well as the differences between Black and White pregnant participants. The results showed that Black pregnant participants had a higher incidence of pregnancy complications, and the associations between different complications and mortality risk differed between Black and White participants.
Review
Medicine, General & Internal
Josef Finsterer
Summary: This review discusses recent advances and knowledge about obstetric complications in mitochondrial disorders(MIDs). The author conducted a narrative review using various databases, and found that obstetric complications in MIDs include eclampsia, preeclampsia, intra uterine growth retardation, polyhydramnion, oligoamnion, decreased fetal movements, premature delivery, stillbirth, blow weakness, dystocia, breech presentation, retained placenta, postnatal hemorrhage, low birth weight, and early postnatal death. Some of these complications are more common in MIDs than in healthy females. Obstetricians should be aware of MIDs and the increased risk of complications in pregnant females with MIDs.
Article
Obstetrics & Gynecology
Linda A. Gallo, Tania F. Gallo, Danielle J. Borg, Karen M. Moritz, Vicki L. Clifton, Sailesh Kumar
Summary: The study found that planned moderate/late preterm births significantly decreased during the COVID-19 lockdown, while there was no impact on extremely or very preterm infants, spontaneous preterm births, or stillbirth rates. A non-significant spike in spontaneous preterm births was observed from late April to early May 2020.
AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY
(2022)
Article
Obstetrics & Gynecology
Lisa Hui, Melvin B. Marzan, Daniel L. Rolnik, Stephanie Potenza, Natasha Pritchard, Joanne M. Said, Kirsten R. Palmer, Clare L. Whitehead, Penelope M. Sheehan, Jolyon Ford, Ben W. Mol, Susan P. Walker
Summary: This retrospective multicenter cohort study examined the impact of COVID-19 vaccination during pregnancy on perinatal outcomes. The study found that vaccinated pregnant women had a lower risk of stillbirth and preterm birth, without any adverse effects on fetal growth or development. Vaccine coverage was influenced by social determinants of health.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2023)
Article
Obstetrics & Gynecology
Monica Minopoli, Laure Noel, Anna Meroni, Margaret Mascherpa, Alex Frick, Basky Thilaganathan
Summary: The objective of this study is to evaluate the positive predictive value (PPV) of first-trimester combined PE screening for various placenta-mediated adverse pregnancy outcomes. The findings suggest that women at high risk for preterm PE are also at increased risk for other adverse outcomes such as PTB, SGA birth, and stillbirth. Therefore, it is recommended to implement higher surveillance and interventions to mitigate these risks.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Pediatrics
Yusuf Topal, Bilge Nur Yardimci-Lokmanoglu, Semra Topuz, Akmer Mutlu
Summary: This study aimed to analyze the spatiotemporal gait characteristics of preterm children from 3 to 4 years old and examine their relationship with general movements assessment. The results showed that extremely preterm and very preterm children had shorter step lengths, while moderate to late preterm children had greater step length variability. The study concluded that the early movement patterns of preterm children may be a marker of later neurodevelopmental dysfunction.
EUROPEAN JOURNAL OF PEDIATRICS
(2023)
Article
Immunology
Christopher Robinson, Janine Oberye, Josephine van Boxmeer, Jessica D. Albano, Hugh Tilson, Anthony Scialli, John A. Vanchiere, Ellis Ides, Daphne Sawlwin, Matthew Hohenboken, Jonathan Edelman
Summary: This study evaluated the safety of a quadrivalent inactivated influenza vaccine in pregnant persons over four influenza seasons. The results showed no safety concerns for both pregnant individuals and infants, and the findings are consistent with existing data.
Article
Acoustics
V. GIORGIONE, O. QUINTERO MENDEZ, A. PINAS, W. ANSLEY, B. THILAGANATHAN
Summary: Preterm birth (PTB) is a major public health issue worldwide, and this study aimed to investigate whether there is a shared uteroplacental etiology in PTB subtypes during the first trimester of pregnancy. The analysis found that factors used to predict preterm PE risk could also be used to predict PTB at < 33 weeks, suggesting a shared etiological pathway for preterm births.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2022)
Article
Medicine, General & Internal
Emma Rasmark Roepke, Ole Bjarne Christiansen, Karin Kallen, Stefan R. Hansson
Summary: Recurrent pregnancy loss (RPL) is associated with placental dysfunctional disorders, with women with RPL having a higher risk during pregnancy and requiring improved antenatal surveillance.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Immunology
Christopher Robinson, Josephine Van Boxmeer, Hugh Tilson, Anthony Scialli, John A. Vanchiere, Ellis Ides, Daphne Sawlwin, Deborah Molrine, Matthew Hohenboken, Jonathan Edelman, Jessica D. Albano
Summary: This study evaluated the pregnancy and infant outcomes of pregnant individuals receiving a cell-based quadrivalent inactivated influenza vaccine (IIV4c). The results showed that the prevalence of adverse pregnancy outcomes or preterm birth, low birth weight, or major congenital malformations (MCMs) in newborns of those vaccinated with IIV4c was similar to the rates observed in US surveillance systems. The safety profile of IIV4c in pregnant individuals was consistent with previously studied influenza vaccines.
Review
Endocrinology & Metabolism
Manuel S. Vidal, Ryan C. V. Lintao, Mary Elise L. Severino, Ourlad Alzeus G. Tantengco, Ramkumar Menon
Summary: Survivors of preterm birth face various disabilities, and addressing the rates of low birth weight, neonatal and maternal morbidities and mortalities is crucial. Research has provided theories on risk factors and clinical manifestations, but there is a lack of biomarkers for early diagnosis. To overcome current limitations, an integrated approach studying the network interaction between different tissues and organs is needed.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Sissel Jessen Weissert, Ellen Margrethe Mikkelsen, Bjarke H. Jacobsen, Elizabeth E. Hatch, Amelia K. Wesselink, Lauren A. Wise, Kenneth J. Rothman, Henrik T. Sorensen, Anne Sofie Dam Laursen
Summary: This study found no meaningful association between consumption of organic food and fecundability in couples trying to conceive. However, slightly higher fecundability was observed among participants with less than 3 cycles of pregnancy attempt time when they consumed more organic food.
PAEDIATRIC AND PERINATAL EPIDEMIOLOGY
(2023)
Article
Ophthalmology
Toke Bek, Bodil Hammer Bech
Summary: Knowledge of visual health in the population is necessary for designing and implementing measures to handle visual handicap. The purpose of the FORSYN project was to study visual health in the Danish population after recent advances in the management of choroidal and retinal vascular disease. The study found that atrophic AMD, neuro-ophthalmic disorders, and other chorioretinal diseases were the most frequent causes of visual loss in Denmark, and recent advances in therapy have reduced central vision loss due to exudative AMD and diabetic retinopathy.
ACTA OPHTHALMOLOGICA
(2023)
Article
Gastroenterology & Hepatology
Gencer Kurt, Helene M. L. Svane, Rune Erichsen, Uffe Heide-Jorgensen, Henrik T. Sorensen, Evan S. Dellon, Elizabeth T. Jensen
Summary: This study is a nationwide and registry-based case-control study that found an association between early-life exposures and eosinophilic esophagitis (EoE). Further research is needed to elucidate the mechanisms underlying the observed associations.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2023)
Article
Environmental Sciences
Eva Cecilie Bonefeld-Jorgensen, Sophie Amalie H. Boesen, Maria Wielsoe, Tine Brink Henriksen, Bodil Hammer Bech, Thorhallur Ingi Halldorson, Manhai Long
Summary: This study examines the possible associations between maternal Persistent Organic Pollutants (POP) exposure, maternal hormone levels, and fetal growth indices (FGI). Lipophilic POP exposure was inversely associated with androgen and estrogen levels, but not strongly associated with thyroid hormones. Higher levels of perfluorinated-alkyl-acid (PFAA) were associated with higher thyroid and androgen levels. The thyroid-peroxidase-antibody (TPO-Ab) and estradiol levels were associated with birth weight and length in sons, but inversely associated with birth weight and length in daughters.
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
(2023)
Article
Obstetrics & Gynecology
Marie Dahl Jorgensen, Ellen M. Mikkelsen, Elizabeth E. Hatch, Kenneth J. Rothman, Lauren A. Wise, Henrik Toft Sorensen, Anne Sofie Dam Laursen
Summary: This study examined the association between socioeconomic status and fecundability among Danish couples trying to conceive. The results showed that lower educational attainment and lower household income were associated with lower fecundability. These findings suggest that socioeconomic disparities may have an impact on reproductive health.
HUMAN REPRODUCTION
(2023)
Article
Endocrinology & Metabolism
Chor-Wing Sing, Tzu-Chieh Lin, Sharon Bartholomew, J. Simon Bell, Corina Bennett, Kebede Beyene, Pauline Bosco-Levy, Brian D. Bradbury, Amy Hai Yan Chan, Manju Chandran, Cyrus Cooper, Maria de Ridder, Caroline Y. Doyon, Cecile Droz-Perroteau, Ganga Ganesan, Sirpa Hartikainen, Jenni Ilomaki, Han Eol Jeong, Douglas P. Kiel, Kiyoshi Kubota, Edward Chia-Cheng Lai, Jeff L. Lange, E. Michael Lewiecki, Julian Lin, Jiannong Liu, Joe Maskell, Mirhelen Mendes de Abreu, James O'Kelly, Nobuhiro Ooba, Alma B. Pedersen, Albert Prats-Uribe, Daniel Prieto-Alhambra, Simon Xiwen Qin, Ju-Young Shin, Henrik T. Sorensen, Kelvin Bryan Tan, Tracy Thomas, Anna-Maija Tolppanen, Katia M. C. Verhamme, Grace Hsin-Min Wang, Sawaeng Watcharathanakij, Stephen J. Wood, Ching-Lung Cheung, Ian C. K. Wong
Summary: In this international study, the researchers analyzed the incidence of hip fractures, post-fracture treatment, and all-cause mortality following hip fractures across different countries and regions. They used patient-level healthcare data from 19 countries and identified 4,115,046 hip fractures from 2005 to 2018. The study revealed variations in the global epidemiology of hip fractures and post-fracture outcomes, highlighting the need for interventions to reduce the burden of osteoporotic fractures.
JOURNAL OF BONE AND MINERAL RESEARCH
(2023)
Article
Public, Environmental & Occupational Health
Louise Lindholdt, Katrine Svendsen, Kathrine W. Rothausen, Bodil H. Bech
Summary: This study aimed to examine the association between social well-being and problematic school absence among Danish adolescents, using a large cohort of adolescents. The results showed that adolescents with low social well-being had higher odds for problematic school absence, and this association was strongest for girls. These findings highlight the importance of early focus and prevention for addressing problematic school absence.
SCANDINAVIAN JOURNAL OF PUBLIC HEALTH
(2023)
Article
Cardiac & Cardiovascular Systems
Soren Korsgaard, Troels Munch, Erzsebet Horvath-Puho, Kasper Adelborg, Christian Fynbo Christiansen, Lars Pedersen, Morten Schmidt, Henrik Toft Sorensen
Summary: This study found that preadmission opioid use is associated with an increased risk of one-year all-cause mortality following an incident myocardial infarction.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Behavioral Sciences
Nils Skajaa, Emil Bjerregaard Riahi, Szimonetta Komjathine Szepligeti, Erzsebet Horvath-Puho, Trine Toft Sorensen, Victor W. Henderson, Henrik Toft Sorensen
Summary: Using Danish nationwide registries, this study found that patients with type 2 diabetes and obesity had a reduced risk of ALS compared to the general population, especially among men and those aged 60 or above.
BRAIN AND BEHAVIOR
(2023)
Article
Cardiac & Cardiovascular Systems
Kimberley G. Miles, Dora Kormendine Farkas, Kristina Laugesen, Henrik Toft Sorensen, Nadine A. Kasparian, Nicolas Madsen
Summary: The incidence of mental health conditions among children with congenital heart disease (CHD) is higher than the general population, particularly among males and those with severe or single-ventricle CHD. Early intervention and mental health support may be especially important for these at-risk populations.
Article
Obstetrics & Gynecology
C. Bisgaard Jensen, B. Hammer Bech, S. Nygaard Hansen, C. Ulrikka Rask, P. Fink, H. Nielsen, T. Meinertz Dantoft, S. Marie Thysen, D. Rytter
Summary: The study found that 30% of menstruating women experienced menstrual changes following COVID-19 vaccination, with several potential risk factors including stress, vaccine concerns, severe COVID-19 infection, and immediate vaccine symptoms being associated with these reports.
HUMAN REPRODUCTION
(2023)
Article
Neurosciences
Kasper Bonnesen, Uffe Heide-Jorgensen, Henrik Toft Sorensen, Morten Schmidt
Summary: This study compared the discriminatory performance of the Danish comorbidity index for acute myocardial infarction (DANCAMI), the Charlson comorbidity index (CCI), the Elixhauser comorbidity index (ECI), and the CHA2DS2-VASc score in predicting ischemic stroke, cardiovascular mortality, and all-cause mortality after atrial fibrillation/flutter. The results showed that DANCAMI had similar predictive performance to CCI, ECI, and CHA2DS2-VASc for ischemic stroke and cardiovascular mortality risks. DANCAMI also had better predictive performance for all-cause mortality risk compared to the baseline and CHA2DS2-VASc.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2023)
Article
Pediatrics
Elizabeth T. Jensen, Helene M. Svane, Rune Erichsen, Gencer Kurt, Uffe Heide-Jorgensen, Henrik T. Sorensen, Evan S. Dellon
Summary: This population-based case-control study in Denmark found an association between maternal and infant use of antibiotics and acid suppressants and increased risk of developing EoE. The risk was highest when exposure occurred near the time of delivery. Early life exposure may be a critical period for risk and risk mitigation.
Editorial Material
Health Care Sciences & Services
Henrik Toft Sorensen, Frederik Pagh Bredahl Kristensen
LANCET REGIONAL HEALTH-EUROPE
(2023)
Article
Health Care Sciences & Services
Henrik Toft Sorensen, Lars Pedersen, Nick van Es, Harry R. Bueller, Erzsebet Horvath-Puho
Summary: Despite improvements in cancer treatment, venous thromboembolism is strongly associated with poor long-term survival in cancer patients.
LANCET REGIONAL HEALTH-EUROPE
(2023)