Synthesis and antitumor mechanisms of a copper(ii) complex of anthracene-9-imidazoline hydrazone (9-AIH)

Stabilization of G-Quadruplex DNA, Inhibition of Telomerase Activity, and Tumor Cell Apoptosis by Organoplatinum(II) Complexes with Oxoisoaporphine

(2015) Zhen-Feng Chen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Isofraxidin, a potent reactive oxygen species (ROS) scavenger, protects human leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in p53-independent manner

(2014) Peng Li et al.   APOPTOSIS

Synthesis, DNA interaction and anticancer activity of copper(II) complexes with 4′-phenyl-2,2′:6′,2″-terpyridine derivatives

(2014) Jie-Wen Liang et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Highly cytotoxic DNA-interacting copper(ii) coordination compounds

(2014) Rosa F. Brissos et al.   Metallomics

Selective anticancer copper(ii)-mixed ligand complexes: targeting of ROS and proteasomes

(2014) Chew Hee Ng et al.   Metallomics

ROS-Mediated Cytotoxic Effect of Copper(II) Hydrazone Complexes against Human Glioma Cells

(2014) Angel Recio Despaigne et al.   MOLECULES

A mitochondrion-targeting copper complex exhibits potent cytotoxicity against cisplatin-resistant tumor cells through multiple mechanisms of action

(2014) Wen Zhou et al.   Chemical Science

Oxidative stress: the mitochondria-dependent and mitochondria-independent pathways of apoptosis

(2013) Krishnendu Sinha et al.   ARCHIVES OF TOXICOLOGY

An insight into synthetic Schiff bases revealing antiproliferative activities in vitro

(2013) Krzysztof Sztanke et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Advances in Research of Schiff-Base Metal Complexes as Potent Antioxidants

(2013) Irena Kostova et al.   CURRENT MEDICINAL CHEMISTRY

Copper(ii) complex of methionine conjugated bis-pyrazole based ligand promotes dual pathway for DNA cleavage

(2013) Sudipta Bhattacharyya et al.   DALTON TRANSACTIONS

Copper(ii) complexes with 2NO and 3N donor ligands: synthesis, structures and chemical nuclease and anticancer activities

(2013) Chandrasekaran Rajarajeswari et al.   DALTON TRANSACTIONS

DNA binding and cytotoxicity of copper (II) imidazole terpyridine complexes: Role of oxyanion, hydrogen bonding and π–π interaction

(2013) Verasundharam Manickavasagar Manikandamathavan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Membrane Localized Iridium(III) Complex Induces Endoplasmic Reticulum Stress and Mitochondria-Mediated Apoptosis in Human Cancer Cells

(2013) Rui Cao et al.   JOURNAL OF MEDICINAL CHEMISTRY

Comparative Cardiac Toxicity of Anthracyclines In Vitro and In Vivo in the Mouse

(2013) Stefano Toldo et al.   PLoS One

Topoisomerase 2 alpha: a real predictor of anthracycline efficacy?

(2012) Atocha Romero et al.   Clinical & Translational Oncology

Targeting the p53 signaling pathway in cancer therapy – the promises, challenges and perils

(2012) Alexander H Stegh   EXPERT OPINION ON THERAPEUTIC TARGETS

Metal Complexes as DNA Intercalators

(2011) Hong-Ke Liu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Antitumor Activity of Metal-Chelating Compound Dp44mT Is Mediated by Formation of a Redox-Active Copper Complex That Accumulates in Lysosomes

(2011) D. B. Lovejoy et al.   CANCER RESEARCH

Versatile Schiff-base hydrazone fluorescent receptors: Synthesis, spectroscopy and complexation studies

(2011) Cristina Núñez et al.   INORGANICA CHIMICA ACTA

Synthesis, characterization, and in vitro antitumor properties of gold(III) compounds with the traditional Chinese medicine (TCM) active ingredient liriodenine

(2011) Zhen-Feng Chen et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

p53 and its mutants in tumor cell migration and invasion

(2011) Patricia A. J. Muller et al.   JOURNAL OF CELL BIOLOGY

Study on potential antitumor mechanism of a novel Schiff Base copper(II) complex: Synthesis, crystal structure, DNA binding, cytotoxicity and apoptosis induction activity

(2011) Xin Qiao et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Mitochondria Determine the Efficacy of Anticancer Agents that Interact with DNA but Not the Cytoskeleton

(2011) K. Hara et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Copper complexes as therapeutic agents

(2011) Clare Duncan et al.   Metallomics

Anthracyclines and ellipticines as DNA-damaging anticancer drugs: Recent advances

(2011) Rene Kizek et al.   PHARMACOLOGY & THERAPEUTICS

Cell cycle and cell death in disease: past, present and future

(2010) B. Zhivotovsky et al.   JOURNAL OF INTERNAL MEDICINE

OLEX2: a complete structure solution, refinement and analysis program

(2009) Oleg V. Dolomanov et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Study of interaction between kaempferol–Eu3+ complex and DNA with the use of the Neutral Red dye as a fluorescence probe

(2009) Guowen Zhang et al.   SENSORS AND ACTUATORS B-CHEMICAL

Mutant p53 Gain-of-Function in Cancer

(2009) M. Oren et al.   Cold Spring Harbor Perspectives in Biology