Article
Psychiatry
Tomisin Iwajomo, Susan J. Bondy, Claire de Oliveira, Patricia Colton, Kathryn Trottier, Paul Kurdyak
Summary: Individuals diagnosed with eating disorders in hospital settings have a five to seven times higher mortality rate compared to the overall population, with males experiencing higher mortality rates than females across all age groups.
BRITISH JOURNAL OF PSYCHIATRY
(2021)
Review
Psychology, Clinical
Madeleine Wilkop, Tracey D. Wade, Ella Keegan, Sarah Cohen-Woods
Summary: Previous research found that individuals who did not meet full criteria for AN, BN, or BED but met criteria for EDNOS displayed high levels of psychiatric and physical morbidity. The present study aimed to determine whether the revised DSM-5 criteria for eating disorders were better at distinguishing between full criteria eating disorders and OSFED and UFED. Meta-analyses comparing various measures were conducted, revealing that OSFED showed more eating pathology compared to AN, but no difference in general psychopathology. OSFED also had more physical health impairments. These findings suggest that the DSM-5 criteria may not adequately capture the clinical severity of OSFED.
CLINICAL PSYCHOLOGY REVIEW
(2023)
Review
Health Care Sciences & Services
Egzona Fetahi, Anders Stjerne Sogaard, Magnus Sjogren
Summary: This systematic review aimed to assess the effects of motivational interviewing and motivational enhancement therapy on patients with eating disorders. The findings indicate that the impact of MET/MI on motivation, eating disorder symptoms, and BMI remains unclear.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Editorial Material
Psychology, Clinical
Phillipa Hay
Summary: This commentary discusses a systematic review that reveals the similarity in symptoms and severity between people with atypical anorexia nervosa and those with anorexia nervosa. It also highlights the problem of overlap and crossover between different eating disorders diagnoses and argues for the need for distinct diagnoses both at assessment and over time. The article suggests that future delineations should be based on empirical research, including neuroscience.
INTERNATIONAL JOURNAL OF EATING DISORDERS
(2023)
Review
Nutrition & Dietetics
Michael J. Butler, Alexis A. Perrini, Lisa A. Eckel
Summary: Alterations in the gut microbiome and immune system may play a role in maintaining and exacerbating eating behavior dysregulation in disorders like anorexia and bulimia, and could potentially serve as biomarkers for increased risk of developing these eating disorders. Research focuses on studying gut dysbiosis, peripheral inflammation, and neuroinflammation in each disorder, as well as exploring data from preclinical rodent models to better understand the biological mechanisms underlying eating disorders. This knowledge is crucial for developing novel and effective treatments for these often difficult-to-treat eating disorders.
Article
Psychiatry
Diane Merino, Alexandre Olivier Gerard, Alexandre Destere, Florence Askenazy, Emmanuelle Dor, Michel Benoit, Faredj Cherikh, Milou-Daniel Drici
Summary: This study investigates the potential triggers for eating disorders, specifically anorexia nervosa (AN) and bulimia nervosa (BN). Using real-world data from the WHO safety database, the study finds a correlation between certain drugs such as isotretinoin, lamivudine, nevirapine, and zidovudine, and the development or relapse of AN and BN. It suggests that mental health conditions should be assessed before treatment initiation to identify patients at risk.
PSYCHIATRY RESEARCH
(2023)
Article
Agriculture, Dairy & Animal Science
Ana Myriam Lavin-Perez, Cristina Martin-Sanchez, Beatriz Martinez-Nunez, Luis Lucio Lobato-Rincon, Santos Villafaina, Israel Gonzalez-Garcia, Ana Mata-Cantero, Montserrat Graell, Eugenio Merellano-Navarro, Daniel Collado-Mateo
Summary: This study aims to evaluate the effects of dog-assisted therapy on adolescents with eating disorders, with significant improvements expected based on the known benefits of animal-assisted therapies in different populations.
Review
Pediatrics
Anastasia Petropoulou, Georgia Bakounaki, Maria G. Grammatikopoulou, Dimitrios P. Bogdanos, Dimitrios G. Goulis, Tonia Vassilakou
Summary: Patients with cystic fibrosis (CF) are at increased risk of developing disordered eating behaviors and eating disorders (EDs) due to the emphasis placed on diet and ideal body weight. Body weight is a significant concern for CF patients, especially women. The onset of disordered eating is often linked to pulmonary infection. Research on the prevalence of EDs in CF patients is conflicting. More research is needed, considering factors such as comorbidities and important outcomes like lung health.
Article
Psychiatry
Geovanny Genaro Reivan Ortiz, Cristhian Javier Rivera Tapia, Braulio Andres Elizalde Martinez, Daniel Icaza
Summary: This study used a structural equation model to evaluate predictive variables of perfectionism in patients with Anorexia Nervosa, Bulimia Nervosa, and OCD, and found a significant correlation among these disorders.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Psychology, Clinical
Lauren Breithaupt, Danielle L. Kahn, Meghan Slattery, Franziska Plessow, Christopher Mancuso, Alyssa Izquierdo, Melissa J. Dreier, Kendra Becker, Debra L. Franko, Jennifer J. Thomas, Laura Holsen, Elizabeth A. Lawson, Madhusmita Misra, Kamryn T. Eddy
Summary: This study examines the course of low-weight restrictive eating disorders in adolescents and finds that persistence is high, crossover occurs but is less frequent, and recovery is rare. Innovative treatment approaches are urgently needed for these disorders.
JOURNAL OF CLINICAL CHILD AND ADOLESCENT PSYCHOLOGY
(2022)
Article
Psychiatry
Andreas Birgegard, Emma Forsen Mantilla, Lisa Dinkler, Elin Hedlund, Androula Savva, Henrik Larsson, Cynthia M. Bulik
Summary: The validity of diagnoses in the Swedish National Patient Register (NPR) is crucial for supporting research and policy recommendations. A comparison with the integrated National Quality Registers (QR) showed that the ED diagnoses in NPR have acceptable validity, providing valuable data for research purposes.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Review
Behavioral Sciences
Anna E. Atchison, Hana F. Zickgraf
Summary: From the literature review, it can be concluded that orthorexia nervosa is closely related to trait and disordered restrictive eating symptoms of anorexia nervosa, as well as weight control motivations for food choice. However, it is less consistently related to binge-spectrum eating disorder symptoms, emotional eating, uncontrolled eating, or body dissatisfaction/shape and weight concerns.
Review
Behavioral Sciences
Libera Siciliano, Giusy Olivito, Maria Leggio
Summary: This review examines the volumetric and functional changes in the cerebellum of individuals with eating disorders (EDs) and proposes that the cerebellum plays a critical role in the pathophysiology of EDs, requiring further investigation.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2022)
Review
Behavioral Sciences
Anna E. Atchison, Hana F. Zickgraf
Summary: The study reviewed the literature on the relationship between orthorexia nervosa (ON) and eating disorder (ED) symptoms. The results indicated that ON is consistently related to trait and disordered restrictive eating symptoms of anorexia nervosa, as well as weight control motivations for food choice. However, ON was less consistently related to binge-spectrum eating disorder symptoms, emotional eating, uncontrolled eating, or body dissatisfaction/shape and weight concerns.
Article
Psychology, Developmental
Alexandra D. Convertino, Aaron J. Blashill
Summary: This study found high rates of comorbid psychiatric disorders in 9-10 year old children with eating disorders, particularly anxiety, attention deficit/hyperactivity disorder, and mood disorders. Clinicians should be aware of the possibility of eating disorders in this age group and the associated severe comorbidity, considering referrals for specialty mental health care.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2022)
Article
Clinical Neurology
Claudia Pisanu, Emma Lundin, Martin Preisig, Mehdi Gholam-Rezaee, Enrique Castelao, Giorgio Pistis, Kathleen R. Merikangas, Jennifer Glaus, Alessio Squassina, Maria Del Zompo, Helgi B. Schioth, Jessica Mwinyi
Article
Psychology, Clinical
Derek B. Kosty, Richard F. Farmer, John R. Seeley, Kathleen R. Merikangas, Daniel N. Klein, Jeff M. Gau, Susan C. Duncan, Peter M. Lewinsohn
ADDICTIVE BEHAVIORS
(2020)
Article
Clinical Neurology
Elizabeth D. Ballard, Cristan A. Farmer, Bridget Shovestul, Jennifer Vande Voort, Rodrigo Machado-Vieira, Lawrence Park, Kathleen R. Merikangas, Carlos A. Zarate
Article
Psychiatry
Diana Paksarian, Betina B. Trabjerg, Kathleen R. Merikangas, Ole Mors, Anders D. Borglum, David M. Hougaard, Merete Nordentoft, Thomas Werge, Carsten B. Pedersen, Preben B. Mortensen, Esben Agerbo, Henriette Thisted Horsdal
BRITISH JOURNAL OF PSYCHIATRY
(2020)
Review
Clinical Neurology
Lydia Sequeira, Steve Perrotta, Jennifer LaGrassa, Kathleen Merikangas, David Kreindler, Deepa Kundur, Darren Courtney, Peter Szatmari, Marco Battaglia, John Strauss
JOURNAL OF AFFECTIVE DISORDERS
(2020)
Review
Clinical Neurology
Emma K. Stapp, Tamar Mendelson, Kathleen R. Merikangas, Holly C. Wilcox
JOURNAL OF AFFECTIVE DISORDERS
(2020)
Article
Psychiatry
Anita Restrepo, Tohar Scheininger, Jon Clucas, Lindsay Alexander, Giovanni A. Salum, Kathy Georgiades, Diana Paksarian, Kathleen R. Merikangas, Michael P. Milham
Review
Clinical Neurology
Greg Murray, John Gottlieb, Maria Paz Hidalgo, Bruno Etain, Philipp Ritter, Debra J. Skene, Corrado Garbazza, Ben Bullock, Kathleen Merikangas, Vadim Zipunnikov, Haochang Shou, Robert Gonzalez, Jan Scott, Pierre A. Geoffroy, Benicio N. Frey
Article
Psychiatry
Diana Paksarian, Kara E. Rudolph, Emma K. Stapp, Gideon P. Dunster, Jianping He, Daniel Mennitt, Samer Hattar, Joan A. Casey, Peter James, Kathleen R. Merikangas
Article
Psychology, Developmental
Dominique Rudaz, Caroline L. Vandeleur, Mehdi Gholam, Enrique Castelao, Marie-Pierre F. Strippoli, Pierre Marquet, Jean-Michel Aubry, Kathleen R. Merikangas, Martin Preisig
Summary: The onset of mood disorders is often preceded by identifiable depressive episodes and nonmood disorders, with these precursors differing by mood subtype in offspring. High-risk offspring with these precursors should be closely monitored to prevent the further development of MDD or conversion to BPD.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2021)
Article
Psychiatry
Emma K. Stapp, Stacey C. Williams, Luther G. Kalb, Calliope B. Holingue, Kathryn Van Eck, Elizabeth D. Ballard, Kathleen R. Merikangas, Joseph J. Gallo
JOURNAL OF PSYCHOSOMATIC RESEARCH
(2020)
Review
Neurosciences
Gideon P. Dunster, Joel Swendsen, Kathleen Ries Merikangas
Summary: Mobile technologies have provided valuable insights into the circadian system, sleep patterns, and motor activity in individuals with bipolar disorder (BD). The use of real-time monitoring has revealed diverse sleep disturbances, variability in motor activity, and evening orientation among BD patients. Future research should focus on identifying common biological pathways that influence the interrelations between sleep, physical activity, and circadian patterns. Collaborative efforts in applying multimodal sensor technology will enhance our understanding of the mechanisms and dynamics of BD.
NEUROPSYCHOPHARMACOLOGY
(2021)
Article
Psychiatry
Rachel F. L. Walsh, Brooke Sheppard, Lihong Cui, Cortlyn Brown, Anna Van Meter, Kathleen R. Merikangas
JOURNAL OF PSYCHIATRIC RESEARCH
(2020)
Article
Psychiatry
Lisa M. Horowitz, Deborah J. Snyder, Edwin D. Boudreaux, Jian-Ping He, Colin J. Harrington, June Cai, Cynthia A. Claassen, Joan E. Salhany, Tram Dao, John F. Chaves, David A. Jobes, Kathleen R. Merikangas, Jeffrey A. Bridge, Maryland Pao
Article
Clinical Neurology
Bhanu Prakash Kolla, Jian-Ping He, Meghna P. Mansukhani, Mark A. Frye, Kathleen Merikangas
