期刊
METABOLOMICS
卷 11, 期 5, 页码 1465-1470出版社
SPRINGER
DOI: 10.1007/s11306-014-0770-7
关键词
HILIC; Reversed phase; LC-MS; Organic acids; Bile acids; Beer
资金
- EPSRC
- Thermo Fisher Scientific
- Wellcome Trust, the Scottish Universities Life Science Alliance
The serial coupling of a reversed-phase liquid chromatography (RPLC) column to a hydrophilic interaction liquid chromatography (HILIC) column has been developed in recent years for the detection of polar and nonpolar metabolites. TCA intermediates, bile acid standards and numerous polar and non-polar metabolites extracted from beer were analysed using a combined RPLC/HILIC method. Non-polar metabolites were retained by the RPLC column. Polar metabolites not retained by the RPLC column were retained and separated by the HILIC column. The results from this study validate this simple yet powerful metabolomics approach.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据