Article
Public, Environmental & Occupational Health
Casey Crump, Jan Sundquist, Kristina Sundquist
Summary: This study aimed to examine the risks of ADHD in preterm and early term birth survivors and found that both preterm and early term birth were associated with increased risks of ADHD in males and females, independently of other covariates and shared familial factors.
ANNALS OF EPIDEMIOLOGY
(2023)
Article
Psychology, Developmental
Adelar Pedro Franz, Arthur Caye, Barbara Calil Lacerda, Flavia Wagner, Rita C. Silveira, Renato Soibelmann Procianoy, Carlos Renato Moreira-Maia, Luis Augusto Rohde
Summary: The study developed an individualized risk calculator for ADHD in VP/VLBW newborns, which showed good performance in identifying high-risk children at 6 years old. This tool could offer more effective early intervention compared to traditional approaches.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2022)
Article
Biochemistry & Molecular Biology
Susu Qu, Xiangyu Zhou, Zhicheng Wang, Yi Wei, Han Zhou, Xinshuang Zhang, Qingjie Zhu, Yanmin Wang, Quanjun Yang, Likun Jiang, Yuan Ma, Yuan Gao, Lei Kong, Li Zhang
Summary: By studying the single-cell resolution of Drosophila, we found that methylphenidate and atomoxetine have different effects on neuronal and glial cells, as well as distinct transcriptional changes. Methylphenidate has a stronger response on dopamine receptor genes, while the effect of atomoxetine is relatively weaker.
MOLECULAR PSYCHIATRY
(2023)
Article
Psychology, Multidisciplinary
Morgan M. Grotewiel, Megan E. Crenshaw, Amelia Dorsey, Elizabeth Street
Summary: Hyperfocus and flow are intense concentration experiences associated with reduced perception of irrelevant stimuli and improved task performance. Hyperfocus has been historically seen as a symptom of ADHD, autism, or schizophrenia, while flow is regarded as an enjoyable experience in positive psychology. Recent studies suggest that hyperfocus and flow may be the same phenomenon viewed from different perspectives.
CURRENT PSYCHOLOGY
(2023)
Article
Multidisciplinary Sciences
Hsin-Yi Fan, Cheuk-Kwan Sun, Yu-Shian Cheng, Weilun Chung, Ruu-Fen Tzang, Hsien-Jane Chiu, Chun-Ning Ho, Kuo-Chuan Hung
Summary: This study provides a systematic review and analysis of the effectiveness of electroencephalogram-based neurofeedback (EEG-NF) in treating the core symptoms of attention-deficit hyperactivity disorder (ADHD) in adolescents/adults. The results suggest that EEG-NF can effectively improve inattention symptoms, but its effectiveness in reducing hyperactivity/impulsivity remains inconclusive.
SCIENTIFIC REPORTS
(2022)
Article
Psychiatry
Dara E. Babinski, Erika F. H. Saunders, Fan He, Duanping Liao, Amanda M. Pearl, Daniel A. Waschbusch
Summary: This study examined the diagnostic indicators, clinical characteristics, and functional impairment associated with adult ADHD using electronic medical records and self-report measures. The results showed a significant difference in prevalence of ADHD between self-report screening and medical records. ADHD was found to contribute to functional impairment even when controlling for other psychiatric comorbidities.
PSYCHIATRY RESEARCH
(2022)
Article
Chemistry, Physical
Jian Huang, Yun Wang, Zhaomin Zhong, Yurong Ma, Keru Deng, Changhong Liu, Hui Huang, Yang Liu, Xin Ding, Zhenhui Kang
Summary: This study demonstrates that carbon dots derived from ascorbic acid can improve ADHD behavior by regulating the circadian system and dopamine signaling pathway, offering a potential application for the treatment of ADHD with degradable and bio-safe carbon dots.
Review
Biochemistry & Molecular Biology
E. M. Bruxel, C. R. Moreira-Maia, G. C. Akutagava-Martins, T. P. Quinn, M. Klein, B. Franke, M. Ribases, P. Rovira, C. Sanchez-Mora, D. B. Kappel, N. R. Mota, E. H. Grevet, C. H. D. Bau, M. Arcos-Burgos, L. A. Rohde, M. H. Hutz
Summary: This study conducted a meta-analysis to investigate the association between ADGRL3 gene variants and ADHD susceptibility in children and adults, finding significant correlation in children but not in adults. The results suggest that ADGRL3 gene is predominantly associated with childhood ADHD.
MOLECULAR PSYCHIATRY
(2021)
Article
Psychology, Multidisciplinary
Erica D. Musser, Stephanie S. J. Morris, Kathleen Feeney, Rosario Pintos Lobo, Edward F. Ester
Summary: Inattention is a key symptom of ADHD, but the mechanisms underlying it are unclear. More specific approaches are needed to link disruptions in cognitive performance with ADHD behaviors. A pilot study found that even typically developing children did not maximally extract and combine information to maximize rewards in a cognitive task targeting attention selection mechanisms.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Medicine, General & Internal
Johannes Lieslehto, Jari Tiihonen, Markku Laehteenvuo, Ellenor Mittendorfer-Rutz, Antti Tanskanen, Heidi Taipale
Summary: This study investigated the impact of pharmacotherapy on suicide risk in patients with borderline personality disorder (BPD). The results indicated that ADHD medication may reduce the risk of suicide, while mood stabilizers and antidepressants may increase the risk. The findings suggest that benzodiazepines should be used with caution due to their association with increased suicide risk in patients with BPD.
Review
Pediatrics
Yarden S. Fraiman, Genevieve Guyol, Dolores Acevedo-Garcia, Andrew F. Beck, Heather Burris, Tumaini R. Coker, Henning Tiemeier
Summary: Preterm birth is associated with an increased risk of ADHD, and both prematurity and ADHD have impacts on various aspects of pediatric life-course. The ADHD Care Cascade provides a framework for individuals to access appropriate services and treatments for ADHD. Racial and ethnic inequities affect the risk of preterm birth and steps along the ADHD Care Cascade. Inequalities accumulate over time to magnify the neurodevelopmental impact of preterm birth on vulnerable children throughout their life-course.
Article
Pediatrics
Li-Fan Pai, Der-Shiun Wang, Wan-Fu Hsu, Shao-Wei Huang, Chi-Hsiang Chung, Shyi-Jou Chen, Wu-Chien Chien, Der-Ming Chu
Summary: This study found that children with ADHD have a higher risk of central precocious puberty. Early referral to a pediatric endocrinologist for evaluation can lead to correct diagnosis. Early intervention treatment with gonadotropin-releasing hormone agonist may improve final height in children with central precocious puberty.
PEDIATRIC RESEARCH
(2022)
Review
Multidisciplinary Sciences
Jung Tae Kim, Kibong Kim, Lin Ang, Hye Won Lee, Jun-Yong Choi, Myeong Soo Lee
Summary: This article describes a systematic review that aims to evaluate the effectiveness of acupuncture as a treatment for ADHD. The study will conduct literature searches in multiple databases and analyze the selected studies using the Cochrane Risk of Bias Assessment Tool. The findings of this review will be used to support relevant health policies and practices.
Review
Medicine, General & Internal
Margherita Barbuti, Marco Maiello, Vincenza Spera, Alessandro Pallucchini, Giulio E. Brancati, Angelo G. I. Maremmani, Giulio Perugi, Icro Maremmani
Summary: Adults with ADHD often have comorbid substance use disorder (SUD), leading to greater severity of both disorders and additional challenges for treatment. Current research on pharmacological management of ADHD with comorbid SUD is limited, particularly in regards to the long-term effects of stimulant medications on dopamine signaling. Evidence suggests that high doses of stimulant medications have moderate efficacy on ADHD symptoms in ADHD-SUD subjects, but there is a risk for misuse. Atomoxetine is recommended for ADHD with comorbid cocaine or amphetamine use disorder, but its effectiveness in reducing addictive behavior is not well-demonstrated. For other subtypes of SUD, both atomoxetine and stimulant drugs have limited impact on addictive behavior, and a combination of ADHD treatment and SUD-specific strategies is recommended.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Biochemistry & Molecular Biology
Samuele Cortese, Minjin Song, Luis C. Farhat, Dong Keon Yon, Seung Won Lee, Min Seo Kim, Seoyeon Park, Jae Won Oh, San Lee, Keun-Ah Cheon, Lee Smith, Corentin J. Gosling, Guilherme V. Polanczyk, Henrik Larsson, Luis A. Rohde, Stephen V. Faraone, Ai Koyanagi, Elena Dragioti, Joaquim Radua, Andre F. Carvalho, Jae Il Shin, Marco Solmi
Summary: Data on ADHD incidence, prevalence, and burden from the Global Burden of Disease study from 1990 to 2019 were presented. The study found that the global age-standardized incidence and prevalence of ADHD were 0.061% and 1.13% respectively in 2019. From 1990 to 2019, there was a decrease in global age-standardized prevalence and incidence. Males had approximately 2.5 times higher incidence, prevalence, and burden compared to females.
MOLECULAR PSYCHIATRY
(2023)