Lipoic acid protects dopaminergic neurons in LPS-induced Parkinson’s disease model

Effects of alpha-lipoic acid on spatial learning and memory, oxidative stress, and central cholinergic system in a rat model of vascular dementia

(2015) Ran-ran Zhao et al.   NEUROSCIENCE LETTERS

Alpha-lipoic acid treatment is neurorestorative and promotes functional recovery after stroke in rats

(2015) Kang-Ho Choi et al.   Molecular Brain

Effects of Lipoic Acid on Immune Function, the Antioxidant Defense System, and Inflammation-Related Genes Expression of Broiler Chickens Fed Aflatoxin Contaminated Diets

(2014) Yan Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Lipoic acid – biological activity and therapeutic potential

(2014) Anna Gorąca et al.   Pharmacological Reports

LPS-induced oxidative stress and inflammatory reaction in the rat striatum

(2014) Karolina Noworyta-Sokołowska et al.   Pharmacological Reports

Down-regulation of microglial activity attenuates axotomized nigral dopaminergic neuronal cell loss

(2013) Dae-Yong Song et al.   BMC NEUROSCIENCE

Protective effect of lipoic acid against oxidative stress is mediated by Keap1/Nrf2-dependent heme oxygenase-1 induction in the RGC-5 cellline

(2013) Yoshiki Koriyama et al.   BRAIN RESEARCH

NADPH oxidase and aging drive microglial activation, oxidative stress, and dopaminergic neurodegeneration following systemic LPS administration

(2013) Liya Qin et al.   GLIA

α-Lipoic acid attenuates LPS-induced cardiac dysfunction through a PI3K/Akt-dependent mechanism

(2013) Surong Jiang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Pesticides, Microglial NOX2, and Parkinson's Disease

(2013) Thomas Taetzsch et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

α-Lipoic acid suppresses migration and invasion via downregulation of cell surface β1-integrin expression in bladder cancer cells

(2013) Masao Yamasaki et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

DJ-1 deficiency triggers microglia sensitivity to dopamine toward a pro-inflammatory phenotype that is attenuated by rasagiline

(2013) Dorit Trudler et al.   JOURNAL OF NEUROCHEMISTRY

Activation of microglia induces symptoms of Parkinson’s disease in wild-type, but not in IL-1 knockout mice

(2013) Sachiko Tanaka et al.   Journal of Neuroinflammation

Pro-inflammatory cytokine-mediated ferroportin down-regulation contributes to the nigral iron accumulation in lipopolysaccharide-induced Parkinsonian models

(2013) Z. Zhang et al.   NEUROSCIENCE

Anti-inflammatory effects of lipoic acid through inhibition of GSK-3β in lipopolysaccharide-induced BV-2 microglial cells

(2013) Yoshiki Koriyama et al.   NEUROSCIENCE RESEARCH

Age-Dependent Modulation of Synaptic Plasticity and Insulin Mimetic Effect of Lipoic Acid on a Mouse Model of Alzheimer’s Disease

(2013) Harsh Sancheti et al.   PLoS One

Intranasal LPS-Mediated Parkinson’s Model Challenges the Pathogenesis of Nasal Cavity and Environmental Toxins

(2013) Qing He et al.   PLoS One

Neonatal exposure to lipopolysaccharide enhances accumulation of α-synuclein aggregation and dopamine transporter protein expression in the substantia nigra in responses to rotenone challenge in later life

(2013) Lu-Tai Tien et al.   TOXICOLOGY

NADPH Oxidase 1-Mediated Oxidative Stress Leads to Dopamine Neuron Death in Parkinson's Disease

(2011) Dong-Hee Choi et al.   ANTIOXIDANTS & REDOX SIGNALING

Animal models of Parkinson's disease: a source of novel treatments and clues to the cause of the disease

(2011) Susan Duty et al.   BRITISH JOURNAL OF PHARMACOLOGY

Lipoic acid protects against reperfusion injury in the early stages of cerebral ischemia

(2010) Barry J. Connell et al.   BRAIN RESEARCH

Mechanisms Underlying Inflammation in Neurodegeneration

(2010) Christopher K. Glass et al.   CELL

Prophylaxis with α-lipoic acid against lipopolysaccharide-induced brain injury in rats

(2009) Anna Gorąca et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

A Nurr1/CoREST Pathway in Microglia and Astrocytes Protects Dopaminergic Neurons from Inflammation-Induced Death

(2009) Kaoru Saijo et al.   CELL

The lipopolysaccharide Parkinson’s disease animal model: mechanistic studies and drug discovery

(2008) Garima Dutta et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Restoration of Blood Total Glutathione Status and Lymphocyte Function Following α-Lipoic Acid Supplementation in Patients with HIV Infection

(2008) Raxit J. Jariwalla et al.   JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE

Glial reactions in Parkinson's disease

(2007) Patrick L. McGeer et al.   MOVEMENT DISORDERS