Review
Medicine, General & Internal
Xiali Teng, Min Jiang, Xiaowei Zhu, Rongrong Dou, Donglan Yuan, Junxing Huang, Hong Yu
Summary: This case report presents a rare instance of splenic metastasis from endometrial adenocarcinoma, emphasizing the importance of monitoring for recurrence after primary treatment.
Review
Medicine, General & Internal
Linxian Zhao, Mingxiu Sui, Jiannan Li, Kai Zhang
Summary: This article reports a rare case of isolated splenic metastasis from colorectal cancer and reviews the relevant literature, providing insights into the management of this condition.
Article
Medicine, General & Internal
Milorad Reljic, Boris Tadic, Katarina Stosic, Milica Mitrovic, Nikola Grubor, Stefan Kmezic, Miljan Ceranic, Vladimir Milosavljevic
Summary: Modern oncology practice and new antitumor drugs have improved disease-free intervals in lung cancer patients. The 8th edition of the TNM classification includes oligometastatic disease for the first time, describing patients with limited distant metastasis who may have a slower biological behavior. This case report presents a 56-year-old man with a radiologically diagnosed splenic lesion suspected to be a metastatic lesion from primary lung cancer. The patient underwent a splenectomy, which can improve disease-free survival and prevent complications.
Review
Medicine, General & Internal
Yifan Chu, Fulan Xu, Zhengguang Ren, Xinyao Hu, Luyao Wang, Jing Yue
Summary: Choriocarcinoma is a highly malignant trophoblastic tumor that commonly occurs in women of childbearing age. It primarily metastasizes through the bloodstream, with the lung, vagina, and brain being the most common sites. Splenic metastasis is rare and can lead to misdiagnosis as ectopic pregnancy or other diseases.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Medicine, General & Internal
Jia-Ming Wu, Ao Zhang, Yu Dong, Si-Hong Lin, Jin-Cheng Meng, Can-Tu Fang
Summary: Colorectal cancer is the second leading cause of cancer-related deaths worldwide, with a high rate of metastasis. This case study reports a rare occurrence of testicular metastasis from ascending colon cancer.
Review
Medicine, Research & Experimental
Rehan Ahmad, Jaikee Kumar Singh, Amoolya Wunnava, Omar Al-Obeed, Maha Abdulla, Sandeep Kumar Srivastava
Summary: Colorectal cancer is the third most common cancer globally, with prevention methods being crucial for management. It is primarily caused by unhealthy lifestyle habits and genetic mutations, with a rising trend among young individuals.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
(2021)
Review
Oncology
Luigi Marongiu, Heike Allgayer
Summary: Evidence suggests that microorganisms, including specific viruses and bacteriophages, may play a significant role in the oncogenesis and progression of colorectal cancer. However, the mechanisms underlying these associations are not fully understood. Various viruses, such as EBV, HPV, JCV, and CMV, have been linked to CRC, along with bacteriophages. The complex interplay between different species within the microbiome and their impact on colorectal cells and the microenvironment may explain the challenges in establishing clear causal links between specific viral infections and CRC.
MOLECULAR ONCOLOGY
(2022)
Review
Oncology
Dongxue Kang, Danyang Zhao, Xiaodi Jiang, Deming Li
Summary: This is the first reported case of isolated splenic metastasis from primary fallopian tube carcinoma. The diagnosis was made through blood tests and abdominal CT scan. The patient underwent laparoscopic splenectomy and had a good recovery. This case highlights the importance of serum tumor marker assessment, medical imaging examination, and history of malignancy during follow-up.
FRONTIERS IN ONCOLOGY
(2023)
Review
Oncology
Yilun Koethe, Nicole Wilson, Govindarajan Narayanan
Summary: This article is a practical guide for using IRE in colorectal cancer liver metastases, providing guidance on patient selection, procedural technique, anesthesia, imaging, and outcomes for healthcare professionals in interventional radiology, oncology, surgery, and anesthesiology.
INTERNATIONAL JOURNAL OF HYPERTHERMIA
(2022)
Article
Gastroenterology & Hepatology
Sung Chul Lee, Hee Cheol Kim, Woo Yong Lee, Seong Hyeon Yun, Yong Beom Cho, Jung Wook Huh, Yoon Ah Park, Jung Kyong Shin
Summary: Synchronous isolated PALN dissection in patients with colorectal cancer metastasis can significantly improve survival rates without increasing postoperative complications, especially in cases of right colon cancer with PALN metastasis.
COLORECTAL DISEASE
(2021)
Review
Oncology
Joris J. van den Broek, Tess van Gestel, Sabrine Q. Kol, Anne M. van Geel, Remy W. F. Geenen, Wilhelmina H. Schreurs
Summary: IPNs are frequently encountered in CRC patients, with 15% showing up on staging CT scans. A pooled analysis of 18 studies involving 8637 patients revealed that 16% of these patients had IPNs that turned out to be metastatic disease during follow up. Predictors of malignancy risk for IPNs include regional lymph node metastases, liver metastases, IPN size and number. A risk stratification model is recommended to guide follow up decisions for CRC patients with IPNs.
Article
Oncology
Zongmei Zheng, Xinxin Hou, Zhaoxiang Bian, Wei Jia, Ling Zhao
Summary: This review explores the crucial role of gut microbiota in the metastasis of colorectal cancer (CRC) and elucidates the molecular mechanisms through which gut microbiota contribute to the formation of a tumor-permissive microenvironment, as well as facilitate malignant transformation and dissemination of tumor cells, thus mediating CRC metastasis.
Article
Oncology
Yoon Jung Oh, Deok Hee Kim, Bang Wool Eom, Hong Man Yoon, Young-Woo Kim, Keun Won Ryu
Summary: A retrospective study of 1038 patients with proximal advanced gastric cancer undergoing total gastrectomy found that prophylactic splenic hilar lymph node dissection without splenectomy did not improve long-term survival outcomes. Therefore, this procedure may not be essential for patients with proximal advanced gastric cancer as well as those with greater curvature involvement or Borrmann type IV disease.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Review
Oncology
Justin Kwan, Uei Pua
Summary: Liver is the most common site of metastasis in colorectal cancer patients, with surgery being the only potential curative option for a small percentage of patients. Advances in modern chemotherapy and personalized biological agents have improved overall survival in patients with unresectable liver metastasis. Liver-directed intra-arterial therapies are increasingly being considered to improve local tumor response and reduce systemic side effects in patients with dominant liver metastatic disease or limited extrahepatic disease.
Article
Multidisciplinary Sciences
Oh Jeong, Han Hong Lee, Hoon Hur, Hyoung-Il Kim
Summary: The study aimed to evaluate the impact of no.10 lymph node dissection on the long-term survival of patients with Borrmann type 4 gastric cancer. The results showed that patients who underwent no.10 lymph node dissection had better survival rates compared to those without dissection. Therefore, it is recommended to perform no.10 lymph node dissection during total gastrectomy for patients with Borrmann type 4 gastric cancer.
SCIENTIFIC REPORTS
(2023)
Article
Engineering, Mechanical
Wael Slika, George Saad
JOURNAL OF ENGINEERING MECHANICS
(2018)
Article
Engineering, Mechanical
Wael Slika, George Saad
JOURNAL OF ENGINEERING MECHANICS
(2018)
Article
Engineering, Civil
Mayssa Dabaghi, George Saad, Naser Allhassania
EARTHQUAKE SPECTRA
(2019)
Article
Construction & Building Technology
Nooralhuda F. Saleh, Ali A. Zalghout, Samir A. Sari Ad Din, Ghassan R. Chehab, George A. Saad
ROAD MATERIALS AND PAVEMENT DESIGN
(2020)
Article
Construction & Building Technology
Louise Bichara, George Saad, Wael Slika
MATERIALS AND STRUCTURES
(2019)
Article
Construction & Building Technology
Reem Bitar, George Saad, Elie Awwad, Helmi El Khatib, Mounir Mabsout
JOURNAL OF BUILDING ENGINEERING
(2020)
Article
Construction & Building Technology
Lea Ghalieh, Elie Awwad, George Saad, Helmi Khatib, Mounir Mabsout
Summary: This study investigated the use of natural hemp fabric to strengthen existing concrete columns, analyzing the effects of variables such as the number of fabric layers, column length/diameter ratio, and presence of transverse reinforcement. The experimental results showed significant impacts of these variables on the strength and post-peak behavior of the confined columns.
MAGAZINE OF CONCRETE RESEARCH
(2021)
Article
Construction & Building Technology
Angela J. Haddad, Ghassan R. Chehab, George A. Saad
Summary: A new rutting prediction model developed using deep neural network techniques shows enhanced predictive power compared to commonly used models. This model is also utilized to assess and rank the impact of different model inputs on rutting, with traffic and climatic conditions identified as having the highest influence.
INTERNATIONAL JOURNAL OF PAVEMENT ENGINEERING
(2021)
Article
Construction & Building Technology
Angela J. Haddad, George A. Saad, Ghassan R. Chehab
Summary: This study develops a probabilistic framework using Ensemble Kalman Filter (EnKF) techniques to update parameters in generic rutting predictive models while considering uncertainties. By continuously updating the models and minimizing prediction errors, the framework improves the accuracy of rutting predictions.
INTERNATIONAL JOURNAL OF PAVEMENT ENGINEERING
(2023)
Article
Engineering, Geological
Imad El Chiti, Shadi Najjar, George Saad, Salah Sadek
Summary: This paper studies the development of lateral stresses behind rigid walls in the context of p-y curves, and provides insight into the p-y response behind rigid walls under static and cyclic loading conditions. The results indicate that the proposed experimental setup yields repeatable and consistent measurements of the p-y response, and the p-y curves exhibit highly nonlinear behavior.
GEOTECHNICAL TESTING JOURNAL
(2022)
Article
Engineering, Geological
Imad El Chiti, Shadi Najjar, George Saad, Salah Sadek, El Chiti, S. Sadek
Summary: This paper studies the development of lateral earth pressure behind rigid walls using p-y curves. A laboratory-scale retaining wall prototype was used to provide insight on the p-y response under static and cyclic loading conditions. The results show that the p-y relationship is highly nonlinear and not adequately represented by the simple elastic-perfectly plastic model. The cyclic tests indicate a process of densification that dominates the sand's volumetric tendency, leading to an increase in stiffness and maximum pressure at the passive side after 10 loading cycles.
GEOTECHNICAL TESTING JOURNAL
(2023)
Article
Engineering, Civil
Imad Elchiti, George Saad, Shadi S. Najjar
Summary: For structures with underground basement walls, the interaction between the side soil and the walls affects the system response. This study focuses on developing a non-linear p-y model to accurately represent the relationship between lateral earth pressure and wall displacement. The results show that the stress-displacement response is highly non-linear and influenced by factors such as wall height, relative density, and depth below the ground surface. The proposed truncated hyperbolic model provides an improved representation of the passive p-y curves.
GEOMECHANICS AND ENGINEERING
(2023)
Article
Environmental Sciences
Christelle N. Basset, Majdi R. Abou Najm, Ashtarout Ammar, Ryan D. Stewart, Scott C. Hauswirth, Georges Saad
VADOSE ZONE JOURNAL
(2019)
Proceedings Paper
Materials Science, Textiles
Riham Ramadan, George Saad, Elie Awwad, Helmi Khatib, Mounir Mabsout
3RD INTERNATIONAL CONFERENCE ON NATURAL FIBERS: ADVANCED MATERIALS FOR A GREENER WORLD, ICNF 2017
(2017)
Article
Engineering, Civil
Dana E. Nasr, Wael G. Slika, George A. Saad
SMART STRUCTURES AND SYSTEMS
(2018)