Lung cancers unrelated to smoking: characterized by single oncogene addiction?

Previous Lung Diseases and Lung Cancer Risk: A Systematic Review and Meta-Analysis

(2011) Darren R. Brenner et al.   PLoS One

EGFR mutations and the terminal respiratory unit

(2010) Yasushi Yatabe   CANCER AND METASTASIS REVIEWS

Inhibition of ALK, PI3K/MEK, and HSP90 in Murine Lung Adenocarcinoma Induced by EML4-ALK Fusion Oncogene

(2010) Z. Chen et al.   CANCER RESEARCH

Lung Adenocarcinoma From East Asian Never-Smokers Is a Disease Largely Defined by Targetable Oncogenic Mutant Kinases

(2010) Yihua Sun et al.   JOURNAL OF CLINICAL ONCOLOGY

Prognostic Implication of EGFR, KRAS, and TP53 Gene Mutations in a Large Cohort of Japanese Patients with Surgically Treated Lung Adenocarcinoma

(2010) Takayuki Kosaka et al.   Journal of Thoracic Oncology

Korean Ethnicity as Compared with White Ethnicity Is an Independent Favorable Prognostic Factor for Overall Survival in Non-small Cell Lung Cancer before and after the Oral Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Era

(2010) Myung-Ju Ahn et al.   Journal of Thoracic Oncology

Performance Status and Smoking Status Are Independent Favorable Prognostic Factors for Survival in Non-small Cell Lung Cancer: A Comprehensive Analysis of 26,957 Patients with NSCLC

(2010) Tomoya Kawaguchi et al.   Journal of Thoracic Oncology

Genetic variants and risk of lung cancer in never smokers: a genome-wide association study

(2010) Yafei Li et al.   LANCET ONCOLOGY

Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal

(2010) Rocio Sotillo et al.   NATURE

Gefitinib or Chemotherapy for Non–Small-Cell Lung Cancer with Mutated EGFR

(2010) Makoto Maemondo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Anaplastic Lymphoma Kinase Inhibition in Non–Small-Cell Lung Cancer

(2010) Eunice L. Kwak et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genomic Aberrations in Lung Adenocarcinoma in Never Smokers

(2010) Bastien Job et al.   PLoS One

A Gene Expression Signature Associated with “K-Ras Addiction” Reveals Regulators of EMT and Tumor Cell Survival

(2009) Anurag Singh et al.   CANCER CELL

Lung Cancer in Never Smokers: A Call to Action

(2009) C. M. Rudin et al.   CLINICAL CANCER RESEARCH

Immunohistochemical Expression of Estrogen and Progesterone Receptors Identifies a Subset of NSCLCs and Correlates with EGFR Mutation

(2009) M. G. Raso et al.   CLINICAL CANCER RESEARCH

KIF5B-ALK, a Novel Fusion Oncokinase Identified by an Immunohistochemistry-based Diagnostic System for ALK-positive Lung Cancer

(2009) K. Takeuchi et al.   CLINICAL CANCER RESEARCH

Lung Cancer in Never Smokers: Clinical Epidemiology and Environmental Risk Factors

(2009) J. M. Samet et al.   CLINICAL CANCER RESEARCH

Clinical Features and Outcome of Patients With Non–Small-Cell Lung Cancer Who Harbor EML4-ALK

(2009) Alice T. Shaw et al.   JOURNAL OF CLINICAL ONCOLOGY

Impact of Environmental Tobacco Smoke on the Incidence of Mutations in Epidermal Growth Factor Receptor Gene in Never-Smoker Patients With Non–Small-Cell Lung Cancer

(2009) Young Joo Lee et al.   JOURNAL OF CLINICAL ONCOLOGY

Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial

(2009) Tetsuya Mitsudomi et al.   LANCET ONCOLOGY

EML4-ALK lung cancers are characterized by rare other mutations, a TTF-1 cell lineage, an acinar histology and young onset

(2009) Kentaro Inamura et al.   MODERN PATHOLOGY

Gefitinib or Carboplatin–Paclitaxel in Pulmonary Adenocarcinoma

(2009) Tony S. Mok et al.   NEW ENGLAND JOURNAL OF MEDICINE

HER2YVMA drives rapid development of adenosquamous lung tumors in mice that are sensitive to BIBW2992 and rapamycin combination therapy

(2009) S. A. Perera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lung Adenocarcinoma: Modification of the 2004 WHO Mixed Subtype to Include the Major Histologic Subtype Suggests Correlations Between Papillary and Micropapillary Adenocarcinoma Subtypes, EGFR Mutations and Gene Expression Analysis

(2008) Noriko Motoi et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

The Histopathology of BRAF-V600E–mutated Lung Adenocarcinoma

(2008) Samuel A. Yousem et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Novel Germline Mutation: EGFR V843I in Patient With Multiple Lung Adenocarcinomas and Family Members With Lung Cancer

(2008) Koei Ikeda et al.   ANNALS OF THORACIC SURGERY

Novel MEK1 Mutation Identified by Mutational Analysis of Epidermal Growth Factor Receptor Signaling Pathway Genes in Lung Adenocarcinoma

(2008) J. L. Marks et al.   CANCER RESEARCH

Non-solid oncogenes in solid tumors:EML4-ALKfusion genes in lung cancer

(2008) Hiroyuki Mano   CANCER SCIENCE

Frequency and Distinctive Spectrum of KRAS Mutations in Never Smokers with Lung Adenocarcinoma

(2008) G. J. Riely et al.   CLINICAL CANCER RESEARCH

Population Attributable Fraction of Mortality Associated with Tobacco Smoking in Japan: A Pooled Analysis of Three Large-scale Cohort Studies

(2008) Kota Katanoda et al.   JOURNAL OF EPIDEMIOLOGY

Significance of Smoking as a Postoperative Prognostic Factor in Patients with Non-small Cell Lung Cancer

(2008) Takeshi Hanagiri et al.   Journal of Thoracic Oncology

A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

(2008) Rayjean J. Hung et al.   NATURE

Somatic mutations affect key pathways in lung adenocarcinoma

(2008) Li Ding et al.   NATURE