Fatty liver creates a pro-metastatic microenvironment for hepatocellular carcinoma through activation of hepatic stellate cells

Role of the Microenvironment in the Pathogenesis and Treatment of Hepatocellular Carcinoma

(2013) Virginia Hernandez–Gea et al.   GASTROENTEROLOGY

IQGAP1 suppresses TβRII-mediated myofibroblastic activation and metastatic growth in liver

(2013) Chunsheng Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

(2013) Shin Yoshimoto et al.   NATURE

Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology

(2013) Ingmar Mederacke et al.   Nature Communications

Hepatocyte-Stellate Cell Cross-Talk in the Liver Engenders a Permissive Inflammatory Microenvironment That Drives Progression in Hepatocellular Carcinoma

(2012) C. Coulouarn et al.   CANCER RESEARCH

Deactivation of Hepatic Stellate Cells During Liver Fibrosis Resolution in Mice

(2012) Juliane S. Troeger et al.   GASTROENTEROLOGY

Hepatocellular carcinoma in non-alcoholic fatty liver disease: An emerging menace

(2012) György Baffy et al.   JOURNAL OF HEPATOLOGY

ROCK and JAK1 Signaling Cooperate to Control Actomyosin Contractility in Tumor Cells and Stroma

(2011) Victoria Sanz-Moreno et al.   CANCER CELL

Hepatocyte-specific hypoxia-inducible factor-1α is a determinant of lipid accumulation and liver injury in alcohol-induced steatosis in mice

(2011) Bharath Nath et al.   HEPATOLOGY

Hepatic stellate cells: Partners in crime for liver metastases?

(2011) Ningling Kang et al.   HEPATOLOGY

Rho inhibitor prevents ischemia–reperfusion injury in rat steatotic liver

(2011) Shintaro Kuroda et al.   JOURNAL OF HEPATOLOGY

Dietary and Genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression

(2010) Eek Joong Park et al.   CELL

Non-alcoholic fatty liver disease as a risk factor for hepatocellular carcinoma: mechanisms and implications

(2010) F. Stickel et al.   GUT

Nonalcoholic fatty liver disease and hepatocellular carcinoma: A weighty connection

(2010) Brad Q. Starley et al.   HEPATOLOGY

Activated hepatic stellate cells promote tumorigenicity of hepatocellular carcinoma

(2009) Thomas Amann et al.   CANCER SCIENCE

Visceral fat accumulation is an independent risk factor for hepatocellular carcinoma recurrence after curative treatment in patients with suspected NASH

(2009) T Ohki et al.   GUT

Resveratrol amplifies profibrogenic effects of free fatty acids on human hepatic stellate cells

(2009) Lars P. Bechmann et al.   HEPATOLOGY RESEARCH

Hepatocarcinoma cells stimulate the growth, migration and expression of pro-angiogenic genes in human hepatic stellate cells

(2009) Pau Sancho-Bru et al.   LIVER INTERNATIONAL

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY

Liver Myofibroblasts Regulate Infiltration and Positioning of Lymphocytes in Human Liver

(2008) Andrew P. Holt et al.   GASTROENTEROLOGY