Interaction between regulatory T cells and cancer stem cells

Cutting Edge: Expression of TNFR2 Defines a Maximally Suppressive Subset of Mouse CD4+CD25+FoxP3+ T Regulatory Cells: Applicability to Tumor-Infiltrating T Regulatory Cells

(2014) X. Chen et al.   JOURNAL OF IMMUNOLOGY

Dual Roles of Immune Cells and Their Factors in Cancer Development and Progression

(2012) Brian F. Zamarron et al.   International Journal of Biological Sciences

Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells

(2011) Piyush B. Gupta et al.   CELL

M2-Polarized tumor-associated macrophages are associated with poor prognoses resulting from accelerated lymphangiogenesis in lung adenocarcinoma

(2011) Bicheng Zhang et al.   Clinics

TLR2 Stimulation Drives Human Naive and Effector Regulatory T Cells into a Th17-Like Phenotype with Reduced Suppressive Function

(2011) M. H. Nyirenda et al.   JOURNAL OF IMMUNOLOGY

A vascular niche and a VEGF–Nrp1 loop regulate the initiation and stemness of skin tumours

(2011) Benjamin Beck et al.   NATURE

Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and Treg cells

(2011) Andrea Facciabene et al.   NATURE

Hypoxia Potentiates Glioma-Mediated Immunosuppression

(2011) Jun Wei et al.   PLoS One

Tumor-initiating stem cells of squamous cell carcinomas and their control by TGF-  and integrin/focal adhesion kinase (FAK) signaling

(2011) M. Schober et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells

(2011) M. Jinushi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wnt/β-catenin signaling regulates cancer stem cells in lung cancer A549 cells

(2010) Ying Teng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Prognostic impact of the expression of putative cancer stem cell markers CD133, CD166, CD44s, EpCAM and ALDH1 in colorectal cancer

(2010) A Lugli et al.   BRITISH JOURNAL OF CANCER

TGF-β Receptor Inhibitors Target the CD44high/Id1high Glioma-Initiating Cell Population in Human Glioblastoma

(2010) Judit Anido et al.   CANCER CELL

Modulation of T-Cell Activation by Malignant Melanoma Initiating Cells

(2010) T. Schatton et al.   CANCER RESEARCH

Knockout of HIF-1  in tumor-associated macrophages enhances M2 polarization and attenuates their pro-angiogenic responses

(2010) C. Werno et al.   CARCINOGENESIS

Transcriptional crosstalk between TGFβ and stem cell pathways in tumor cell invasion: Role of EMT promoting Smad complexes

(2010) Jonas Fuxe et al.   CELL CYCLE

Glioma-Associated Cancer-Initiating Cells Induce Immunosuppression

(2010) J. Wei et al.   CLINICAL CANCER RESEARCH

Phenotypic and functional switch of macrophages induced by regulatory CD4+ CD25+ T cells in mice

(2010) Guangwei Liu et al.   IMMUNOLOGY AND CELL BIOLOGY

Expression of Costimulatory TNFR2 Induces Resistance of CD4+FoxP3- Conventional T Cells to Suppression by CD4+FoxP3+ Regulatory T Cells

(2010) X. Chen et al.   JOURNAL OF IMMUNOLOGY

Tumor-Conditioned Macrophages Secrete Migration-Stimulating Factor: A New Marker for M2-Polarization, Influencing Tumor Cell Motility

(2010) G. Solinas et al.   JOURNAL OF IMMUNOLOGY

A Decrease of Regulatory T Cells Correlates With Overall Survival After Sunitinib-based Antiangiogenic Therapy in Metastatic Renal Cancer Patients

(2010) Olivier Adotevi et al.   JOURNAL OF IMMUNOTHERAPY

Foxp3+ IL-17+ T cells promote development of cancer-initiating cells in colorectal cancer

(2010) Shaobo Yang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Transforming growth factor-β regulates the sphere-initiating stem cell-like feature in breast cancer through miRNA-181 and ATM

(2010) Y Wang et al.   ONCOGENE

High-Density Gene Expression Analysis of Tumor-Associated Macrophages from Mouse Mammary Tumors

(2009) Laureen S. Ojalvo et al.   AMERICAN JOURNAL OF PATHOLOGY

TGF-β Increases Glioma-Initiating Cell Self-Renewal through the Induction of LIF in Human Glioblastoma

(2009) Silvia Peñuelas et al.   CANCER CELL

DLL4 Blockade Inhibits Tumor Growth and Reduces Tumor-Initiating Cell Frequency

(2009) Timothy Hoey et al.   Cell Stem Cell

Autocrine TGF-β Signaling Maintains Tumorigenicity of Glioma-Initiating Cells through Sry-Related HMG-Box Factors

(2009) Hiroaki Ikushima et al.   Cell Stem Cell

Gene Expression Analysis of Macrophages That Facilitate Tumor Invasion Supports a Role for Wnt-Signaling in Mediating Their Activity in Primary Mammary Tumors

(2009) L. S. Ojalvo et al.   JOURNAL OF IMMUNOLOGY

Identification of IL-17-producing FOXP3+ regulatory T cells in humans

(2009) K. S. Voo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic-Mediated Dysfunction of the Bone Morphogenetic Protein Pathway Inhibits Differentiation of Glioblastoma-Initiating Cells

(2008) Jeongwu Lee et al.   CANCER CELL

Significance of CD90+ Cancer Stem Cells in Human Liver Cancer

(2008) Zhen Fan Yang et al.   CANCER CELL

Identification and Characterization of Ovarian Cancer-Initiating Cells from Primary Human Tumors

(2008) S. Zhang et al.   CANCER RESEARCH

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Cancer Stem Cells and the Ontogeny of Lung Cancer

(2008) Craig D. Peacock et al.   JOURNAL OF CLINICAL ONCOLOGY

Identification of cells initiating human melanomas

(2008) Tobias Schatton et al.   NATURE