Saracatinib (AZD0530) is a potent modulator of ABCB1-mediated multidrug resistancein vitroandin vivo

Structural and Functional Properties of Human Multidrug Resistance Protein 1 (MRP1/ABCC1)

(2012) S.-M. He et al.   CURRENT MEDICINAL CHEMISTRY

Up-regulation of breast cancer resistance protein plays a role in HER2-mediated chemoresistance through PI3K/Akt and nuclear factor-kappa B signaling pathways in MCF7 breast cancer cells

(2011) W. Zhang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Sildenafil Reverses ABCB1- and ABCG2-Mediated Chemotherapeutic Drug Resistance

(2011) Z. Shi et al.   CANCER RESEARCH

Effect of BIBF 1120 on reversal of ABCB1-mediated multidrug resistance

(2011) Qing-feng Xiang et al.   CELLULAR ONCOLOGY

Apatinib (YN968D1) Reverses Multidrug Resistance by Inhibiting the Efflux Function of Multiple ATP-Binding Cassette Transporters

(2010) Y.-j. Mi et al.   CANCER RESEARCH

Phase I Safety, Pharmacokinetics, and Inhibition of Src Activity Study of Saracatinib in Patients with Solid Tumors

(2010) J. Baselga et al.   CLINICAL CANCER RESEARCH

LAPTM4B: A novel cancer-associated gene motivates multidrug resistance through efflux and activating PI3K/AKT signaling

(2010) L Li et al.   ONCOGENE

A phase II trial of the Src-kinase inhibitor AZD0530 in patients with advanced castration-resistant prostate cancer: a California Cancer Consortium study

(2009) Primo N. Lara et al.   ANTI-CANCER DRUGS

Sensitization of ABCG2-overexpressing cells to conventional chemotherapeutic agent by sunitinib was associated with inhibiting the function of ABCG2

(2009) Chun-ling Dai et al.   CANCER LETTERS

Combined Pharmacophore Modeling, Docking, and 3D QSAR Studies of ABCB1 and ABCC1 Transporter Inhibitors

(2009) Ilza K. Pajeva et al.   ChemMedChem

Identifying and Characterizing Binding Sites and Assessing Druggability

(2009) Thomas A. Halgren   Journal of Chemical Information and Modeling

Preclinical anticancer activity of the potent, oral Src inhibitor AZD0530

(2009) Tim P. Green et al.   Molecular Oncology

Vandetanib (Zactima, ZD6474) Antagonizes ABCC1- and ABCG2-Mediated Multidrug Resistance by Inhibition of Their Transport Function

(2009) Li-sheng Zheng et al.   PLoS One

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

(2009) S. G. Aller et al.   SCIENCE

Mutational analysis of ABC proteins

(2008) Tip W. Loo et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Inhibition of P-glycoprotein (ABCB1)- and multidrug resistance-associated protein 1 (ABCC1)-mediated transport by the orally administered inhibitor, CBT-1®

(2008) Robert W. Robey et al.   BIOCHEMICAL PHARMACOLOGY

Lapatinib (Tykerb, GW572016) Reverses Multidrug Resistance in Cancer Cells by Inhibiting the Activity of ATP-Binding Cassette Subfamily B Member 1 and G Member 2

(2008) C.-l. Dai et al.   CANCER RESEARCH

Inhibition of PI3K/Akt partially leads to the inhibition of PrPC-induced drug resistance in gastric cancer cells

(2008) Jie Liang et al.   FEBS Journal