Sustained NF-kappaB activity in chronic lymphocytic leukemia is independent of genetic and epigenetic alterations in the TNFAIP3 (A20) locus

Inhibition of NF- B Signaling by A20 Through Disruption of Ubiquitin Enzyme Complexes

(2010) N. Shembade et al.   SCIENCE

The NF- B negative regulator TNFAIP3 (A20) is inactivated by somatic mutations and genomic deletions in marginal zone lymphomas

(2009) U. Novak et al.   BLOOD

miRNA deregulation by epigenetic silencing disrupts suppression of the oncogene PLAG1 in chronic lymphocytic leukemia

(2009) C. P. Pallasch et al.   BLOOD

TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas

(2009) K. Honma et al.   BLOOD

NF-κB as a prognostic marker and therapeutic target in chronic lymphocytic leukemia

(2009) Chris Pepper et al.   Future Oncology

Rel A Is an Independent Biomarker of Clinical Outcome in Chronic Lymphocytic Leukemia

(2009) Saman Hewamana et al.   JOURNAL OF CLINICAL ONCOLOGY

TNFAIP3(A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma

(2009) Roland Schmitz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A20 is targeted by promoter methylation, deletion and inactivating mutation in MALT lymphoma

(2009) E Chanudet et al.   LEUKEMIA

Mutations of multiple genes cause deregulation of NF-κB in diffuse large B-cell lymphoma

(2009) Mara Compagno et al.   NATURE

Frequent inactivation of A20 in B-cell lymphomas

(2009) Motohiro Kato et al.   NATURE

The ubiquitin-editing enzyme A20 (TNFAIP3) is a central regulator of immunopathology

(2009) Lars Vereecke et al.   TRENDS IN IMMUNOLOGY

Overexpression of TOSO in CLL is triggered by B-cell receptor signaling and associated with progressive disease

(2008) C. P. Pallasch et al.   BLOOD

A20: Central Gatekeeper in Inflammation and Immunity

(2008) Beatrice Coornaert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia

(2008) Maria Chiara Di Bernardo et al.   NATURE GENETICS

Oncogenic CARD11 Mutations in Human Diffuse Large B Cell Lymphoma

(2008) G. Lenz et al.   SCIENCE