Article
Public, Environmental & Occupational Health
Sharayu Mhatre, Ben Lacey, Paul Sherliker, Nilanjan Chatterjee, Preetha Rajaraman, Mahesh Goel, Shraddha Patkar, Vikas Ostwal, Prachi Patil, Shailesh Shrikhande, Garvit Chitkara, Rajendra Badwe, Sarah Lewington, Rajesh Dikshit
Summary: In India, the incidence of gall-bladder cancer is higher in women than in men. This study found a positive association between parity and GBC risk, suggesting that reproductive and hormonal factors play an important role in the development of GBC.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Oncology
Elvin S. Cheng, Louiza S. Velentzis, Marianne Weber, Julia Steinberg, Karen Canfell, Xue Qin Yu
Summary: There is emerging evidence suggesting that oestrogen may be involved in lung cancer development, especially among never-smoking women. A large-scale study in China found that factors such as age at menarche, age at menopause, time since menopause, prior use of oral contraceptives, number of livebirths, breastfeeding, and age at first livebirth were associated with increased risk of lung cancer death among never-smoking women. These findings highlight the potential role of reproductive factors in lung cancer development.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Respiratory System
Marina Dehara, Michael C. Sachs, Susanna Kullberg, Johan Grunewald, Anders Blomberg, Elizabeth Arkema
Summary: The study found that higher sarcoidosis risk was associated with older age at menarche, natural menopause, later age at first pregnancy, and ever hormone replacement therapy (HRT) use. Lower risk was associated with older age at menopause, longer duration of oral contraceptive use, longer duration of HRT use, ever local estrogen therapy (LET) use, and longer duration of LET use. However, the study indicated that it is still unclear whether longer estrogen exposure is associated with reduced sarcoidosis risk due to inconsistency and modest magnitude in the estimates, as well as the wide credible intervals.
BMC PULMONARY MEDICINE
(2022)
Article
Oncology
Zhuoyu Yang, Fei Wang, Fengwei Tan, Wei Cao, Yongjie Xu, Chao Qin, Yiwen Yu, Liang Zhao, Yan Wen, Zheng Wu, Yadi Zheng, Yunyong Liu, Lianzheng Yu, Donghua Wei, Dong Dong, Ji Cao, Shaokai Zhang, Shipeng Yan, Ning Wang, Xianzhen Liao, Lingbin Du, Jiang Li, Ni Li, Wanqing Chen, Jie He
Summary: The study found associations between later age at menarche, later age at first live birth, and benign breast disease history with elevated lung cancer risk. Surgical menopause and other surgeries on the reproductive system in postmenopausal females were predictive of increased lung cancer risk. A nonlinear association was observed for age at menopause, with increased lung cancer risk especially above 50. Although no significant associations were found between longer breastfeeding duration and lung cancer risk overall, a significantly decreased adenocarcinoma risk was noted among nonsmoking females.
TRANSLATIONAL LUNG CANCER RESEARCH
(2021)
Article
Medicine, General & Internal
Ryoko Katagiri, Motoki Iwasaki, Sarah Krull Abe, Md. Rashedul Islam, Md. Shafiur Rahman, Eiko Saito, Melissa A. Merritt, Ji-Yeob Choi, Aesun Shin, Norie Sawada, Akiko Tamakoshi, Woon-Puay Koh, Ritsu Sakata, Ichiro Tsuji, Jeongseon Kim, Chisato Nagata, Sue K. Park, Sun-Seog Kweon, Xiao-Ou Shu, Yu-Tang Gao, Shoichiro Tsugane, Takashi Kimura, Jian-Min Yuan, Seiki Kanemura, Yukai Lu, Yumi Sugawara, Keiko Wada, Min-Ho Shin, Habibul Ahsan, Paolo Boffetta, Kee Seng Chia, Keitaro Matsuo, You-Lin Qiao, Nathaniel Rothman, Wei Zheng, Manami Inoue, Daehee Kang
Summary: This study found that late menarche, early menopause, and a higher number of deliveries were significantly associated with a lower risk of endometrial cancer. These findings from a large pooled study of Asian women add to the growing body of evidence on the association between reproductive factors and endometrial cancer risk.
Article
Medicine, General & Internal
Lijun Zheng, Jinfeng Yin, Siyi Wang, Hui Jiang, Puqi Hu, Ziqing Kang, Pingxin Lv, Weimin Li, Chao Cai
Summary: This study found distinct clinical symptoms and CT features in patients with co-existent PTB and lung cancer, which aid in early diagnosis. Patients with PTB and fibrous calcification may have a higher risk of developing lung cancer. Further multicenter prospective studies are needed to validate these findings.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2021)
Article
Biochemistry & Molecular Biology
Bumhee Yang, Dong-Hwa Lee, Kyungdo Han, Hayoung Choi, Hyung Koo Kang, Dong Wook Shin, Hyun Lee
Summary: A population-based retrospective cohort study in South Korea found that female reproductive factors are associated with the risk of bronchiectasis, with shorter endogenous oestrogen exposure periods showing a higher risk of developing the condition.
Article
Oncology
Raneem Yaseen Hammouz, Magdalena Orzechowska, Dorota Anusewicz, Andrzej K. K. Bednarek
Summary: Sex differences in lung cancer are evident, but studies on this topic are not widely considered. In this study, various methods were used to analyze lung adenocarcinoma data, revealing key differences in immune system regulation and metabolic processes between male and female patients. The study also found different energy production preferences and hormonal effects between the two sexes. Further research is needed to investigate sex-specific gene regulatory networks and the impact of lifestyle factors on metabolic pathways.
Article
Oncology
Nuha El Sharif, Imtithal Khatib
Summary: The study found that factors such as late menarche, long-term use of oral contraceptives, hormone contraceptives, hormone replacement therapy, nulliparity, parental consanguinity marriage, and positive family history were all significantly associated with increased risk of breast cancer among women in the West Bank of Palestine. This highlights the importance of rationalizing the use of reproductive hormones, both for birth control and therapeutic purposes, particularly in this region.
CANCER EPIDEMIOLOGY
(2021)
Article
Public, Environmental & Occupational Health
Fanny Kilpi, Ana Goncalves Soares, Gemma L. Clayton, Abigail Fraser, Paul Welsh, Naveed Sattar, Scott M. Nelson, Kate Tilling, Deborah A. Lawlor
Summary: This study suggests that physical function in women declines with age and reproductive age. The decline in reproductive age is independent of chronological age, but does not seem to be driven by changes in reproductive hormones.
Article
Endocrinology & Metabolism
Jie Li, Wenting Hao, Chunying Fu, Chengchao Zhou, Dongshan Zhu
Summary: This study found that postmenopausal women are more likely to experience memory impairment compared to men, particularly in objective memory. Female reproductive factors such as age at menarche and menopause may influence the risk of memory problems.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Oncology
Jia-Yi Tuo, Hong-Lan Li, Jing Wang, Jie Fang, Yu-Ting Tan, Yong-Bing Xiang
Summary: This study revealed that menstrual and reproductive factors significantly impact liver cancer risk in Chinese women. Hormone replacement therapy and injective contraceptives were positively associated with liver cancer risk in postmenopausal women, while older age at menopause, longer reproductive period, and fewer live births were linked to reduced risk.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2022)
Article
Oncology
Mohammad Taher Parad, Mohammad Fararouei, Ali Reza Mirahmadizadeh, Sima Afrashteh
Summary: The study identified risk factors for thyroid cancer in a high-incidence region in Iran, including benign thyroid diseases, family history, radiation exposure, and family history of other cancers. Protective factors were found to be high blood pressure, higher education, unsaturated fat consumption, and being married. Community-based interventions such as reducing radiation exposure and screening family members with underlying thyroid diseases may help prevent or detect thyroid cancer early. Further studies on the health effects of local herbs are recommended.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Article
Cardiac & Cardiovascular Systems
Maddalena Ardissino, Eric A. W. Slob, Paul Carter, Tormod Rogne, Joanna Girling, Stephen Burgess, Fu Siong Ng
Summary: This study used Mendelian randomization to explore the causal relevance of reproductive factors on cardiovascular disease in women. The results showed that earlier genetically predicted age at first birth, higher genetically predicted number of live births, and earlier genetically predicted age at menarche were associated with increased risk of cardiovascular disease. These findings support the role of reproductive factors in the development of cardiovascular disease in women and identify potential modifiable mediators for clinical intervention.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Public, Environmental & Occupational Health
Meng Wang, Wei-Wei Gong, Qing-Fang He, Ru-Ying Hu, Min Yu
Summary: The study found that women with later age at first pregnancy and longer duration of breastfeeding had a lower risk of thyroid cancer, supporting the role of reproductive factors in thyroid cancer risk.
Article
Oncology
Anita Koushik, Molin Wang, Kristin E. Anderson, Piet van den Brandt, Tess V. Clendenen, A. Heather Eliassen, Jo L. Freudenheim, Jeanine M. Genkinger, Niclas Hakansson, James R. Marshall, Marjorie L. McCullough, Anthony B. Miller, Kim Robien, Thomas E. Rohan, Catherine Schairer, Leo J. Schouten, Shelley S. Tworoger, Ying Wang, Alicja Wolk, Anne Zeleniuch-Jacquotte, Stephanie A. Smith-Warner
CANCER CAUSES & CONTROL
(2015)
Article
Public, Environmental & Occupational Health
Romain Pasquet, Igor Karp, Jack Siemiatycki, Anita Koushik
ANNALS OF EPIDEMIOLOGY
(2016)
Article
Nutrition & Dietetics
Marie-Eve Labonte, Sharon I. Kirkpatrick, Rhonda C. Bell, Beatrice A. Boucher, Ilona Csizmadi, Anita Koushik, Mary R. L'Abbe, Isabelle Massarelli, Paula J. Robson, Isabelle Rondeau, Bryna Shatenstein, Amy F. Subar, Benoit Lamarche
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
(2016)
Article
Public, Environmental & Occupational Health
Ilona Csizmadi, Beatrice A. Boucher, Geraldine Lo Siou, Isabelle Massarelli, Isabelle Rondeau, Didier Garriguet, Anita Koushik, Janine Elenko, Amy F. Subar
PUBLIC HEALTH NUTRITION
(2016)
Article
Nutrition & Dietetics
Vikki Ho, Coraline Danieli, Michal Abrahamowicz, Anne-Sophie Belanger, Vanessa Brunetti, Edgard Delvin, Julie Lacaille, Anita Koushik
BRITISH JOURNAL OF NUTRITION
(2018)
Article
Oncology
Karolina Louvanto, Eduardo L. Franco, Agnihotram V. Ramanakumar, Natasa Vasiljevic, Dorota Scibior-Bentkowska, Anita Koushik, Jack Cuzick, Francois Coutlee, Attila T. Lorincz
INTERNATIONAL JOURNAL OF CANCER
(2015)
Article
Virology
Catherine Rodrigues-Coutlee, Jacques Archambault, Deborah Money, Agnihotram V. Ramanakumar, Janet Raboud, Catherine Hankins, Anita Koushik, Harriet Richardson, Paul Brassard, Eduardo L. Franco, Francois Coutlee
JOURNAL OF CLINICAL VIROLOGY
(2013)
Article
Oncology
Lisa Leung, Anne Grundy, Jack Siemiatycki, Jocelyne Arseneau, Lucy Gilbert, Walter H. Gotlieb, Diane M. Provencher, Kristan J. Aronson, Anita Koushik
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2019)
Letter
Oncology
Anita Koushik, Lisa Leung, Kristan J. Aronson
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2019)
Article
Oncology
Anne Grundy, Vikki Ho, Michal Abrahamowicz, Marie-Elise Parent, Jack Siemiatycki, Jocelyne Arseneau, Lucy Gilbert, Walter H. Gotlieb, Diane M. Provencher, Anita Koushik
INTERNATIONAL JOURNAL OF CANCER
(2020)
Review
Environmental Sciences
Kevin L'Esperance, Geetanjali D. Datta, Samia Qureshi, Anita Koushik
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2020)
Article
Oncology
Anne Grundy, Simran Sandhu, Jocelyne Arseneau, Lucy Gilbert, Walter H. Gotlieb, Kristan J. Aronson, Anita Koushik
Summary: The study found that lifetime caffeine intake was not strongly associated with ovarian cancer risk, but there may be a difference in relationship based on menopausal status.
CANCER EPIDEMIOLOGY
(2022)
Article
Oncology
Kevin LEsperance, Anne Grundy, Michal Abrahamowicz, Jocelyne Arseneau, Lucy Gilbert, Walter H. Gotlieb, Diane Provencher, Anita Koushik
Summary: This population-based case-control study investigates the association between alcohol intake and the risk of overall, borderline, and invasive ovarian cancer. The results suggest that a higher alcohol intake moderately increases the risk of overall ovarian cancer, particularly borderline tumors.
CANCER CAUSES & CONTROL
(2023)
Article
Public, Environmental & Occupational Health
Lisa Leung, Jerome Lavoue, Jack Siemiatycki, Pascal Guenel, Anita Koushik
Summary: This study investigated the relationship between employment in certain occupations or industries, specific occupational exposures, and ovarian cancer risk. The results showed that individuals with occupations such as accountants, hairdressers, sewers, and salespeople had a higher risk of ovarian cancer. Furthermore, working in the retail trade or construction industries was also associated with an increased risk. High cumulative exposure to 18 agents, including cosmetic talc, ammonia, hydrogen peroxide, and hair dust, was positively associated with ovarian cancer risk.
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2023)
Article
Oncology
Anita Koushik, Anne Grundy, Michal Abrahamowicz, Jocelyne Arseneau, Lucy Gilbert, Walter H. Gotlieb, Julie Lacaille, Anne-Marie Mes-Masson, Marie-Elise Parent, Diane M. Provencher, Lesley Richardson, Jack Siemiatycki
CANCER CAUSES & CONTROL
(2017)