Article
Biochemistry & Molecular Biology
Lin Wang, Meihua Xin, Mingchun Li, Wenfeng Liu, Yangfan Mao
Summary: In this study, three new chitosan quaternary phosphonium compounds were synthesized and characterized. Their antibacterial activities against Escherichia coli and Staphylococcus aureus, as well as their antibiofilm activities, were investigated. The results showed that the chitosan quaternary phosphonium salts exhibited stronger antibacterial and antibiofilm activities compared to chitosan quaternary ammonium salt.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Medicinal
Jingjing Zhang, Wenqiang Tan, Qing Li, Xiaorui Liu, Zhanyong Guo
Summary: The study successfully obtained a series of novel CTMCSG hydrogel films with good water stability, thermal stability, drug release capacity, and antibacterial property. The properties of the hydrogel films improved with an increase in the amount of the cross-linking agent, resulting in reduced water vapor permeability.
Article
Biochemistry & Molecular Biology
Wanjing Zou, Jingwei Gu, Jianna Li, Yuanfang Wang, Shiguo Chen
Summary: The study successfully synthesized IQAS and ISB derivatives and systematically investigated the effects of their substitution degree, carbon chain length, and content ratio on water solubility, antibacterial activity, and cytotoxicity of CS derivatives, suggesting that the properties of CS derivatives can be tailored by adjusting the amount of grafted antibacterial agents.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Biochemistry & Molecular Biology
Hongcai Zhang, Tingting Qiu, Yifei Bai, Bin Chen, Juan Yan, Jianxiong Xu
Summary: In this study, cellulose nanocrystals were used to stabilize Lysozyme encapsulated in quaternary ammonium chitosan nanoparticles. The CNC stabilized Lys loaded QC NPs showed potential implications in the food industry for food preservation and packaging, as well as demonstrated good antibacterial activity against Staphylococcus aureus and Vibrio parahaemolyticus.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Polymer Science
Yalan Wang, Juan Du, Haiyong Guo, Renming Liu, Zhiyi Li, Tingyu Yang, Junzhe Ai, Chunbo Liu
Summary: An antibacterial PU coating with QAS was developed and characterized by XPS, FT-IR, and SEM, showing significant antimicrobial activity against both S. aureus and E. coli. Different theoretical molar fractions of DMAPD in chain extenders resulted in varying antibacterial effectiveness, with PU-4 showing the best activity against S. aureus and PU-5 against E. coli.
JOURNAL OF POLYMER RESEARCH
(2022)
Article
Chemistry, Physical
Dhruval K. Joshi, Frank Betancourt, Alyssa McAdorey, Ravi Shekar Yalagala, Andy Poupon, Hongbin Yan
Summary: N,N,N-trimethyl-2(4,4-difluoro-4-bora-3a,4a-diaza-s-indacen-8-yl)ethylammonium iodide (BODIPY quaternary ammonium 17) was successfully synthesized using 4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene as starting material. Although less stable than Rose Bengal, this BODIPY ammonium showed superior photosensitizing efficiency and faster photodegradation rate. It also exhibited antibacterial activity against Bacillus subtilis when exposed to light.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2023)
Article
Materials Science, Paper & Wood
Xin Tang, Zaixing Zhang, Lingxiao Jing, Kun Luan, Sha Zhou, Tonghua Zhang
Summary: A novel antimicrobial compound was synthesized and successfully grafted onto cotton fabric, enhancing its antibacterial function. Chlorination treatment significantly improved the antibacterial activity of the fabric, which showed good antimicrobial durability. This study provides a new approach to enhance the antimicrobial performance of textiles.
Article
Materials Science, Paper & Wood
Peixuan Wu, Yunxi Cui, Zhicheng Sun, Meijuan Cao, Yuanyuan Liu, Kun Fu, Yang Zhou
Summary: In this study, an antibacterial sodium alginate derivative was successfully developed through covalent coupling of organosilane quaternary ammonium salt with sodium alginate. The material exhibited high antibacterial efficiency against Staphylococcus aureus and Escherichia coli, reaching up to 99.6% and 99.3%, respectively. Additionally, the material demonstrated good biocompatibility and potential application in the fabrication of sodium alginate beads.
Article
Chemistry, Applied
Qingyan Pan, Chuang Zhou, Ziming Yang, Zuyu He, Chao Wang, Yunhao Liu, Shuhui Song, Hui Gu, Keqian Hong, Lijuan Yu, Yunhui Qu, Puwang Li
Summary: A multifunctional food packaging composite film with good thermal stability and antibacterial functions was fabricated using HA-CS-NP and PVA, showing potential in inhibiting fruit decay and increasing fruit hardness.
Article
Biochemistry & Molecular Biology
Zonghua Tian, Xia Wu, Li Peng, Na Yu, Guojing Gou, Wenbao Zuo, Jianhong Yang
Summary: In this study, pH-responsive bufadienolides nanocrystals decorated by chitosan quaternary ammonium salt (HE BU NCs) were successfully constructed to improve the bioavailability, release characteristics, and intestinal transport ability of bufadienolides. In vitro studies showed that HE BU NCs could improve the internalization of bufadienolides, induce apoptosis, decrease mitochondrial membrane potential, and increase ROS levels in tumor cells. In vivo experiments demonstrated that HE BU NCs effectively targeted intestinal sites, increased retention time, and exerted antitumor activity through Caspase-3 and Bax/Bcl-2 ratio pathways.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Multidisciplinary
Yuhong Zhu, Pengfei Li, Caikun Liu, Mengqi Jia, Yadong Luo, Dengfeng He, Chunyan Liao, Shiyong Zhang
Summary: The abuse of antibiotics leads to bacterial resistance, and the shortage of antibiotics has created a public health crisis. In this study, a series of photosensitive azobenzene-quaternary ammonium salt smart antibacterial agents were developed to improve antibacterial selectivity and prevent the accumulation of active agents. The compound demonstrated enhanced antibacterial activity after light irradiation and showed intelligent antibacterial properties. It has the potential to be a candidate for disinfectants in public facilities and medical architecture.
CHINESE CHEMICAL LETTERS
(2023)
Article
Materials Science, Multidisciplinary
Fuying Dong, Tiansong Jia, Qin Wang, Yang Liu, Lixia Ma, Shuaijie Li, Xinde Tang, Shengyu Feng
Summary: This paper presents a strategy to prevent leaching of antibacterial agents by tethering quaternary ammonium salt (QAS) groups in the matrix. The hydroxyl-terminated polysiloxanes with QAS groups were successfully synthesized and used to prepare an intrinsic antibacterial silicone rubber with excellent compatibility and durability. The hydrophilicity of the silicone rubber can be adjusted by the content of QAS groups.
MATERIALS TODAY COMMUNICATIONS
(2021)
Article
Polymer Science
Baiqing Song, Tianyi Zhang, Xinfeng Li, Kaili Yang, Jinyu Shan, Yunzhi Dang, Jianhua Ma
Summary: Smart and controllable antibacterial fabrics have great potential in textile, medical, and healthcare fields. In this study, a composite antimicrobial fiber with thermally responsive properties was created by synthesizing nano zinc oxide (ZnO) and combining it with quaternary ammonium chitosan (QAC). The addition of a copper sulphide (CuS) layer further enhanced the antibacterial properties of the materials. These smart responsive composite fibers show promise in medical dressings, special textiles, and healthcare materials.
EUROPEAN POLYMER JOURNAL
(2023)
Article
Biochemistry & Molecular Biology
Yanbing Song, Jin Xing, Li Ren, Xia Xu, Donghua Han, Hao Xu, Liang Zhao, Yang Yu, Shige Wang, Chaobo Liu
Summary: A multi-functional hydrogel with antibacterial properties, hemostasis, and the ability to promote wound healing is proposed in this study. The hydrogel is composed of surfactin, polyvinylpyrrolidone, and methacrylic anhydride grafted quaternary ammonium chitosan. The formation of the hydrogel is triggered by ultraviolet-initiated polymerization, while surfactin is complexed with the hydrogel through hydrogen bonding interaction. This adhesive hydrogel with shape adaptability can cover the wound surface, simulate the microenvironment of the primary extracellular matrix, and promote collagen deposition and inflammatory factor transformation.
MACROMOLECULAR BIOSCIENCE
(2023)
Article
Polymer Science
Abolfazl Heydari, Eva Dusicka, Matej Micusik, Marian Sedlak, Igor Lacik
Summary: In this study, the characteristics of N-[(2-hydroxy-3-trimethylammonium)propyl]chitosan salt (HTCS) were investigated, revealing a significant exchange of chloride counterions during synthesis, with the true degree of quaternization determined by NMR spectroscopy. This phenomenon of counterion exchange was further validated by XPS and shown for quaternized dextran, highlighting the importance of considering counterion type in applications of polyelectrolytes.
Article
Optics
Xi Li, Jie Li, Yingchun Li, Kai Xia
JOURNAL OF LUMINESCENCE
(2016)
Article
Materials Science, Multidisciplinary
Jie Li, Bing Xie, Kai Xia, Chunmao Zhao, Yingchun Li, Shengliang Hu
Article
Chemistry, Physical
Jie Li, Li Wang, Hefeng Zhou, Xuguang Liu, Bingshe Xu
JOURNAL OF ALLOYS AND COMPOUNDS
(2010)
Article
Materials Science, Multidisciplinary
Han Jing, Li Jie
JOURNAL OF WUHAN UNIVERSITY OF TECHNOLOGY-MATERIALS SCIENCE EDITION
(2011)
Article
Materials Science, Multidisciplinary
Jie Li, Xi Li, Shengliang Hu, Yingchun Li, Yuying Hao
Article
Spectroscopy
Jie Li, Junfu Zhao, Hefeng Zhou, Jian Liang, Xuguang Liu, Bingshe Xu
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2011)
Article
Chemistry, Physical
Jie Li, Bing Xie, Kai Xia, Yingchun Li, Jing Han, Chunmao Zhao
Article
Chemistry, Physical
Jie Li, Chunmao Zhao, Kai Xia, Xi Liu, Dong Li, Jing Han
APPLIED SURFACE SCIENCE
(2019)
Article
Chemistry, Analytical
Jing Han, Dong Li, Chunmao Zhao, Xiaoyan Wang, Jie Li, Xinzhe Wu
Article
Materials Science, Multidisciplinary
Xi Liu, Jie Li, Zhaozhou Fang, Chen Wang, Luosheng Shu, Jing Han
JOURNAL OF MATERIALS SCIENCE
(2020)
Article
Materials Science, Multidisciplinary
Luosheng Shu, Yingchun Li, Jie Li, Wengsheng Wang, Sravanthi Vupputuri, Dongdong Yang, Binbin Dong, Nuo Cao, Duo Pan, Rajib Das, Zhanhu Guo
MACROMOLECULAR MATERIALS AND ENGINEERING
(2020)
Article
Polymer Science
Chen Wang, Jie Li, Zhaozhou Fang, Zhirui Hu, Xiaotong Wei, Yang Cao, Jing Han, Yingchun Li
Summary: This paper presents a synthetic method for a crosslinked chitosan quaternary ammonium salt and liquid metal composite hydrogel, which can be used for smart wearable sensors with excellent conductivity and self-healing properties. It is capable of monitoring human activities and discerning subtle motions.
MACROMOLECULAR RAPID COMMUNICATIONS
(2022)
Article
Nanoscience & Nanotechnology
Zhirui Hu, Jie Li, Xiaotong Wei, Chen Wang, Yang Cao, Zhiqiang Gao, Jing Han, Yingchun Li
Summary: This study presents a composite hydrogel with piezoresistive and piezoelectric sensing capabilities for flexible strain sensors. The hydrogel exhibits high sensitivity, fast response, and wide frequency range, while maintaining excellent mechanical properties. This work provides insights into the design of wearable sensors.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Polymer Science
Yiwei Dong, Chen Wang, Zhirui Hu, Shujuan Mao, Xiaotong Wei, Yueqing Fu, Jie Li, Jing Han
Summary: This study reports a novel liquid metal organic hydrogel with low-temperature sensitivity, recyclability, and multiple sensation properties. The organic hydrogel exhibits excellent stretchability and fast responsiveness, making it suitable for sensing applications in low-temperature environments.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
