Article
Nanoscience & Nanotechnology
Shimei Li, Wei Zhang, Xudong Lan, Longfei Tan, Xudong Chen, Kong-Peng Lv, Zhongbing Huang, Li Gou, Jing Wan, Xianwei Meng
Summary: In this study, a new biocompatible nanosensitizer DGPPT with magnetic resonance imaging and mitochondrial targeting capabilities for MW hyperthermia combined with chemotherapy was successfully constructed. The combination of mitochondrial targeting and MW hyperthermia-chemotherapy effectively shrank tumor size, providing a new direction for inhibiting tumor growth.
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Federica Vurro, Ylenia Jabalera, Silvia Mannucci, Giulia Glorani, Alberto Sola-Leyva, Marco Gerosa, Alessandro Romeo, Maria Grazia Romanelli, Manuela Malatesta, Laura Calderan, Guillermo R. Iglesias, Maria P. Carrasco-Jimenez, Concepcion Jimenez-Lopez, Massimiliano Perduca
Summary: MamC-expressed BMNPs have advantages in stable functionalization and molecule release, but face challenges in cell internalization. Encapsulation with PLGA and functionalization with TAT peptide enhance internalization without compromising cell viability.
Article
Pharmacology & Pharmacy
Ziqi Wang, Bo Liu, Jingyao Tu, Jingfeng Xiang, Hui Xiong, Yue Wu, Shuaijie Ding, Daoming Zhu, Dongyong Zhu, Fei Liu, Guangyuan Hu, Xianglin Yuan
Summary: In this study, a sorafenib-loaded PLGA hydrogel system (SPH) was developed and combined with microwave hyperthermia to enhance the sensitivity of radiotherapy (RT). The experiments demonstrated that SPH and MW hyperthermia achieved a double RT sensitization effect and significant tumor inhibition effect.
Article
Chemistry, Multidisciplinary
Zheng Luo, Xiaotong Fan, Ying Chen, Xiyu Lai, Zibiao Li, Yun-Long Wu, Chaobin He
Summary: The designed composite enzyme nanogel system can target cancer cell mitochondria, disrupt the redox homeostasis of mitochondria through catalysis, induce tumor cell apoptosis, and showed good anti-tumor effects in animal experiments.
Article
Materials Science, Multidisciplinary
Shicao Wei, Yingfeng Li, Ke Li, Chao Zhong
Summary: This study successfully created a new functional hybrid material by mimicking the structure of bacterial biofilms and using amyloid-polysaccharide composite matrix. The material combines the toughness of polysaccharide fibers and the functionality of amyloid fusion proteins, allowing it to interact with inorganic materials and be potentially applied in electronics and organic-inorganic interfaces. Additionally, it offers a potential alternative to industrial polymers or plastics with its low-cost and environmentally-friendly nature.
APPLIED MATERIALS TODAY
(2022)
Article
Pharmacology & Pharmacy
Ylenia Jabalera, Alberto Sola-Leyva, Salvatore Calogero Gaglio, Maria P. Carrasco-Jimenez, Guillermo R. Iglesias, Massimiliano Perduca, Concepcion Jimenez-Lopez
Summary: The synergy between directed chemotherapy and thermal therapy utilizing a nanoassembly composed of functionalized biomimetic magnetic nanoparticles (BMNPs) was explored in this study. Results demonstrated that this nanoassembly, capable of mediating drug transport and hyperthermic effects, showed a stronger cytotoxic effect against tumor cells both in vitro and in vivo compared to traditional therapies.
Article
Nanoscience & Nanotechnology
Marta Ribeiro, Meriem Boudoukhani, Efres Belmonte-Reche, Nuria Genicio, Sanna Sillankorva, Juan Gallo, Carlos Rodriguez-Abreu, Nadji Moulai-Mostefa, Manuel Banobre-Lopez
Summary: This study introduces a biocompatible hydrogel with magnetic nanoparticles, allowing controlled drug release and non-invasive monitoring, which is crucial for precise treatment of internal diseases.
ACS APPLIED NANO MATERIALS
(2021)
Article
Pharmacology & Pharmacy
Sergio R. S. Veloso, Eva S. Marta, Pedro V. Rodrigues, Cacilda Moura, Carlos O. Amorim, Vitor S. Amaral, Miguel A. Correa-Duarte, Elisabete M. S. Castanheira
Summary: In this study, multicore-like iron oxide and manganese ferrite nanoparticles were synthesized and combined with nanogels based on chitosan and alginate to create a multimodal drug delivery system. The nanoparticles displayed crystalline structures and different sizes, with improved magnetization and heating efficiency after functionalization. Encapsulated in nanogels, the nanoparticles exhibited high drug encapsulation efficiencies and sustained release, with enhanced release under near-infrared laser irradiation and acidic pH.
Article
Chemistry, Applied
Shabbah Begum, Nor Yuliana Yuhana, Noorashikin Md Saleh, Nur Hidayatul Nazirah Kamarudin, Abu Bakar Sulong
Summary: The focus of the research is on the application of chitosan and its derivatives in removing heavy metals from water bodies, exploring different modification strategies and specific application methods.
CARBOHYDRATE POLYMERS
(2021)
Article
Biochemistry & Molecular Biology
Ying Liu, Xiao Ma, Qimeng Jiang, Guihua Yang
Summary: The challenge of hemorrhage in daily life necessitates timely treatment to reduce the risk of death. The use of loose corn stalk to modify the structure of chitin sponge proves effective in improving its hemostatic properties. The resulting composite sponge, CH/CS4, possesses high water/blood absorption ability, rapid hemostatic time, and low blood loss. It also exhibits superior hemostatic performance, wound healing ability, and cytocompatibility compared to sole chitin and commercial polyvinyl fluoride sponge.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Multidisciplinary Sciences
Gyeongsuk Park, Hyunmin Park, Junyong Seo, Jun Chang Yang, Min Kim, Bong Jae Lee, Steve Park
Summary: The authors developed a hydrogel that mimics thermal homeostasis, providing improved heat trapping and enhanced evaporative cooling. The hydrogel includes materials that reflect and absorb infrared waves for heat trapping at low temperatures, and has a porous structure for enhanced evaporative cooling at high temperatures. An optimized auxetic pattern acts as a heat valve to amplify heat release. This hydrogel provides effective bidirectional thermoregulation, making it useful for autonomic nervous system disorders and susceptible soft robotics.
NATURE COMMUNICATIONS
(2023)
Article
Biotechnology & Applied Microbiology
Aijia Xing, Yang Hu, Wei Wang, Francesco Secundo, Changhu Xue, Xiangzhao Mao
Summary: A novel chitinase gene from Streptomyces bacillaris was cloned and expressed in Escherichia coli BL21. The purified recombinant enzyme (SbChiAJ103) exhibited exochitinase activity and was immobilized on magnetic nanoparticles (MNPs) using mono-methyl adipate as a linker. The immobilized SbChiAJ103@MNPs showed improved pH tolerance, temperature stability, and storage stability compared to the free enzyme. The immobilization of SbChiAJ103 paves the way for efficient and eco-friendly commercial production of (GlcNAc)2.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2023)
Article
Polymer Science
Arisa Kongprayoon, Gareth Ross, Nanteetip Limpeanchob, Sararat Mahasaranon, Winita Punyodom, Paul D. Topham, Sukunya Ross
Summary: Bio-derived and biocompatible nanogels based on poly(lactic acid) (PLA) and silk sericin (SS) were synthesized and embedded within nanofibers for potential use in tissue regeneration. Higher crosslink densities resulted in smaller nanogel particles with reduced drug release accumulation.
Article
Chemistry, Applied
Takuya Hashiguchi, Kazuya Yamamoto, Jun-ichi Kadokawa
Summary: This study successfully fabricated a highly flexible self-assembled cellulose film by scaling down the chitin nanofibers, and further enhanced the flexibility by multi-point ionic cross-linking with anionic polysaccharide. The superior mechanical properties and efficient compositing properties were attributed to the scaling down of the chitin nanofibers.
CARBOHYDRATE POLYMERS
(2021)
Article
Biochemistry & Molecular Biology
Xiaomeng Li, Lei Jiang, Manqing Yan, Hong Bi, Qiyang Wang
Summary: In this study, chitin nanofiber reinforced composite hydrogels of PACF were prepared via a facile one-pot method. The obtained hydrogel exhibits good transparency, excellent mechanical properties, and high strain sensitivity, making it suitable for detecting human motion.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biophysics
M. R. Poorna, R. Jayakumar, Jyh-Ping Chen, Ullas Mony
Summary: Induced pluripotent stem cells (iPSCs) have great potential in regenerative medicine, and improving culture methods, such as using hydrogels as substrates, can support iPSC adhesion, proliferation, and differentiation. Using hydrogels may help generate large numbers of clinical-grade cells for potential clinical applications.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Biochemistry & Molecular Biology
Mahalakshmi Pandian, V. Anil Kumar, R. Jayakumar
Summary: The newly developed Cs-Ocd bandage with porous structure, enhanced swelling property, and controlled release of Ocd can significantly reduce skin infections. The bandage exhibits good hemostatic potential, antimicrobial, and anti-biofilm activity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Mahalakshmi Pandian, Vignesh Selvaprithviraj, Aathira Pradeep, Jayakumar Rangasamy
Summary: The developed N,O-CMC/AgNps hydrogel is adhesive, injectable, conductive, bio-compatible, and exhibits antibacterial and self-healing properties, making it suitable for the treatment of infected wounds.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Aathira Pradeep, Nivethitha Ashok, V. Priya, Anoop V. Pillai, Riju Ramachandran Menon, V. Anil Kumar, R. Jayakumar
Summary: This study introduces a novel antibacterial product, a chitosan hydrogel loaded with a high-end antibiotic, for the treatment of Gram-negative bacterial infections. The product exhibits excellent stability and biocompatibility, and is capable of inhibiting biofilm formation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Review
Biochemistry & Molecular Biology
N. Sanoj Rejinold, Goeun Choi, Jin-Ho Choy
Summary: Clay-based bio-inorganic nanohybrids, such as layered double hydroxides (LDH), have been extensively researched in the field of biomedicine for drug delivery and bio-imaging applications. Recent trends show that these materials can be hybridized with photo-active biomolecules to achieve selective anti-cancer effects through various photo/chemotherapies. The use of LDH enhances the stability and controllability of the therapies, improving overall phototherapeutic performance.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Materials Science, Ceramics
Aathira Pradeep, Praveen Kerala Varma, Thennavan Arumugam, Anjaly Maravattikal Vijayan, Anil Kumar Vasudevan, Jayakumar Rangasamy
Summary: Deep sternal wound infection (mediastinitis) after cardiac surgery can be caused by both Gram-positive and Gram-negative bacteria. The incidence of sternal infection is increasing in current practice and is associated with longer hospital stay, higher medical costs, and increased mortality. A new antibacterial bone adhesive cement called TPAV, composed of tetracalcium phosphate, phosphoserine, amikacin, and vancomycin, has been developed and characterized. TPAV exhibits effective antibacterial properties against various bacteria, inhibiting their growth and biofilm formation. In in vivo studies using a rat sternotomy model infected with Staphylococcus aureus and Escherichia coli, TPAV demonstrated significant inhibitory activity. This study highlights the potential of TPAV as a preventive treatment for mediastinitis in clinical settings.
CERAMICS INTERNATIONAL
(2023)
Review
Biochemistry & Molecular Biology
Geun-Woo Jin, N. Sanoj Rejinold, Jin-Ho Choy
Summary: Polyphosphazenes (PPZs), with their structural flexibility and biodegradability, have attracted great interest as synthetic polymers in the field of biomedical science. The introduction of various functional groups has enabled the development of multi-functionalized PPZs, which have shown potential as biomaterials in the form of nanoparticles (NPs) and hydrogels for various applications such as drug delivery, bioimaging, phototherapy, bone regeneration, and dental liners.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Polymer Science
Geun-Woo Jin, N. Sanoj Rejinold, Jin-Ho Choy
Summary: Polymeric micelles, as carriers for therapeutic compounds, have attracted attention due to their ability to solubilize poorly water-soluble drugs, biocompatibility, and accumulation in tumors. Additional functionality can be achieved through surface modification and stimuli-sensitive groups. This review highlights the development of multifunctional polymeric micelles in cancer therapy, including applications in tumor imaging and theragnosis.
Review
Engineering, Biomedical
Kavipriya Murugaiyan, Sivashanmugam Amirthalingam, Nathaniel Suk-Yeon Hwang, Rangasamy Jayakumar
Summary: In tissue engineering, cells, biological/mechanical cues, and scaffolds are the three key components. Growth factors and their derivatives, bioactive molecules, and gene regulators are the common biological cues used. Fibroblast growth factors (FGFs) have been extensively studied for their influence on physiological functions, particularly FGF-18 which is associated with osteoblast differentiation and bone regeneration. FGF-18 can enhance bone formation by stimulating certain pathways and has shown promising results when incorporated into hydrogels and scaffolds. This review focuses on the functions and potential outcomes of using FGF-18 in bone regeneration.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2023)
Review
Engineering, Biomedical
Arun Kumar Rajendran, Deepthi Sankar, Sivashanmugam Amirthalingam, Hwan D. Kim, Jayakumar Rangasamy, Nathaniel S. Hwang
Summary: Cells and tissues can sense the mechanical properties of substrates or matrices, and this leads to downstream responses at the cellular, nuclear, and epigenetic levels. Researchers have found connections between cellular mechanosignalling pathways and cellular physiology, differentiation, and tissue pathology. Mechanosignalling, either alone or in combination with other pathways, plays a significant role in the fate determination, development, and organization of cells and tissues.
BIOMATERIALS RESEARCH
(2023)
Review
Engineering, Biomedical
Chameli Ratan, Arya Mangalath Arian, Rajalakshmi Rajendran, Rangasamy Jayakumar, Mar Masson, Sabitha Mangalathillam
Summary: Skin cancer, predominantly observed in populations of European descent, can be treated with spice-derived nutraceuticals like curcumin that have anti-neoplastic activity, trigger apoptosis, and inhibit signaling pathways. However, curcumin has limitations in terms of bioavailability and solubility, hindering its use in clinical settings. Nanoformulations based on curcumin have been developed to overcome these limitations and show promise as effective treatment modalities for skin cancer.
BIOMEDICAL MATERIALS
(2023)
Article
Polymer Science
Mahalakshmi Pandian, G. Reshma, C. Arthi, Mar Masson, Jayakumar Rangasamy
Summary: Wound healing is a complex process, and the presence of bacteria can hinder this process, resulting in infectious wounds. Numerous biomedical and biomaterial research efforts have been made over the past 20 years to address this issue. Polymeric scaffolds and hydrogels are the best candidates for developing effective drug-delivery biomaterials.
EUROPEAN POLYMER JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Shameer Pillarisetti, Veena Vijayan, Jayakumar Rangasamy, Rizia Bardhan, Saji Uthaman, In-Kyu Park
Summary: We report a multi-stimulus responsive alginate nanogel that responds to changes in pH and redox potential in the tumor microenvironment. Combined with chemotherapy and photodynamic therapy (PDT), this nanogel enhances the therapeutic effect in breast cancer and melanoma by releasing a hydrophobic photosensitizer and a cytotoxic agent.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2023)
Article
Chemistry, Physical
Dipankar Ghosh, Pooja Chaudhary, Aathira Pradeep, Surendra Singh, Jayakumar Rangasamy, Krishna K. Damodaran
Summary: Low molecular weight N-oxide hydrogelators were synthesized by modifying the pyridyl functional groups of hydrazone/semicarbazone compounds. The water solubility of the hydrazone gelator was enhanced by the structural modification to pyridyl-N-oxide hydrazides. The stability, morphology, and stimuli-responsive properties of the gels were analyzed, and the hydrazone gels showed antibacterial activity and biocompatibility.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Engineering, Biomedical
Ramu Janarthanan, Rangasamy Jayakumar, Subramania Iyer
Summary: This study aimed to improve the efficiency of autologous fat grafting (AFG) by using a hydrogel as a carrier and adding platelet-rich plasma (PRP). The results showed that the hydrogel and PRP group had enhanced cell viability and proliferation, as well as improved angiogenesis and adipogenesis compared to the control group. Thus, the hydrogel-based fat graft system with PRP can optimize the clinical outcomes of AFG.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
