期刊
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
卷 65, 期 -, 页码 375-382出版社
ELSEVIER
DOI: 10.1016/j.ijbiomac.2014.01.034
关键词
Agar Controlled drug release; 5-Amino salicylic acid; Microwave assisted synthesis; Polyacrylamide grafted agar
资金
- University Grants Commission, New Delhi, India vides [F-39-800/2010(SR)]
- Department of Science and Technology, New Delhi [08/12-09141]
Agar has been modified by microwave assisted grafting with acrylamide monomer, resulting in poly acrylamide grafted agar (Ag-g-PAM). The synthesized grades of Ag-g-PAM were characterized by standard physico-chemical characterization techniques (FTIR spectroscopy, elemental analysis, scanning electron microscopy (SEM)) to ascertain the intended grafting. The synthesized graft copolymer (Ag-g-PAM) has been investigated (in vitro) for controlled and colon targeted release of 5-amino salicylic acid (5-ASA). (C) 2014 Elsevier B.V. All rights reserved.
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