期刊
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
卷 57, 期 -, 页码 138-141出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.ijbiomac.2013.03.011
关键词
Nano hydroxyapatite; Fucoidan; Nano composites; Tissue engineering
资金
- Marine Bioprocess Research Centre of the Marine Bio 21 Center
- Ministry of Land, Transport and Maritime, Republic of Korea
Hydroxyapatite (HAp) is the promising biomaterials to construct the article bone from the last two decades. In the present study, we have developed hydroxyapatite-fucoidan (HApF) nanocomposite for bone tissue engineering and subsequently characterized by different analytical techniques for bone graft substitute. The chemical characterization suggested that the prepared nanocomposite HApF have amorphous nature, crystal size between 41 and 153 nm was observed. The biochemical characterization inferred that the prepared nanocomposite were non-toxic and mineralization effect of HApF was observed two times higher then HAp. Hence, HApF is the promising biomaterial and could be used for bone tissue construct. (C) 2013 Elsevier B.V. All rights reserved.
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