期刊
INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS
卷 34, 期 2, 页码 180-184出版社
WICHTIG EDITORE
DOI: 10.5301/IJAO.2011.6393
关键词
Bioinspiration; Gecko adhesion; Tissue engineering; Biodegradability; Tympanic membrane restoration
资金
- European Science Foundation [ESF 07-FANAS-FP-001-EBioAdI]
- German Research Foundation (DFG)
We studied the effects of pillar dimensions and stiffness of biocompatible and biodegradable micropatterned surfaces on adhesion on different compliant substrates. The micropatterned adhesives were based on biocompatible polydimethylsiloxane (PDMS) and biodegradable poly(lactic-co-glycolic) acid (PLGA) polymer systems. Micropatterned and non-patterned compliant PDMS did not show significant differences in adhesion on compliant mice ear skin or on gelatin-glycerin model substrates. However, adhesion measurements for micropatterned stiff PLGA on compliant gelatin-glycerin model substrates showed significant enhancement in pull-off strengths compared to non-patterned controls.
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