Review
Critical Care Medicine
Christiaan L. Meuwese, Daniel Brodie, Dirk W. Donker
Summary: This article provides an overview of pivotal factors that potentially prevent successful weaning from V-A ECMO support. It emphasizes the importance of a systematic approach to optimize clinical management and improve patient outcomes.
Article
Engineering, Biomedical
Antonio F. Corno, Gail M. Faulkner, Chris Harvey
Summary: Mobile ECMO team consists of ECMO-trained healthcare professionals and utilizes road, air, or combination transfers. Over the past decade, 571 patients have undergone mobile ECMO transfers, with the majority being completed by road. The average duration of mobile ECMO transfer is 5.5 hours, and it proves to be safe and reliable for transferring the sickest patients.
Article
Surgery
Andre Y. Son, Linh Ngo Khanh, Hae Soo Joung, Andres Guerra, Azad S. Karim, Randy McGregor, Amit Pawale, Duc Thinh Pham, Karen J. Ho
Summary: ALI and significant bleeding are common occurrences after peripheral VA-ECMO cannulation. Cannulation in the operating room is associated with a decreased risk of ALI but an increased risk of bleeding, while ultrasound-guided cannulation decreases the risk of bleeding. DPC placement does not significantly affect the risk of ALI or bleeding.
JOURNAL OF VASCULAR SURGERY
(2021)
Editorial Material
Cardiac & Cardiovascular Systems
Graham Stockdale, John P. Breinholt, Erik Ellsworth, Nisha Bhatia, Wayne J. Franklin, Jordan D. Awerbach
Summary: Supplemental Digital Content is available for viewing in the text.
CIRCULATION-CARDIOVASCULAR IMAGING
(2021)
Review
Critical Care Medicine
Waiel Abusnina, Mahmoud Ismayl, Ahmad Al-abdouh, Vaishnavi Ganesan, Mostafa Reda Mostafa, Osama Hallak, Emily Peterson, Mahmoud Abdou, Andrew M. Goldsweig, Ahmed Aboeata, Khagendra Dahal
Summary: This study compared the clinical outcomes of Impella versus extracorporeal membrane oxygenation (ECMO) in patients with cardiogenic shock (CS). The results showed that the use of Impella was associated with lower rates of in-hospital mortality, bleeding, and stroke compared to ECMO.
Article
Cardiac & Cardiovascular Systems
Xixiang Lin, Feifei Yang, Yixin Chen, Xu Chen, Wenjun Wang, Wenxiu Li, Qiushuang Wang, Liwei Zhang, Xin Li, Yujiao Deng, Haitao Pu, Xiaotian Chen, Xiao Wang, Dong Luo, Peifang Zhang, Daniel Burkhoff, Kunlun He
Summary: A DL framework was developed for the automatic detection and quantification of atrial septal defects (ASDs) in color Doppler echocardiography. The DL models achieved high accuracy in view selection, ASD detection, and measurement of defect size and residual rim. The application of this model can improve the accuracy and efficiency of using color Doppler in clinical practice for screening and quantification of ASDs.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Surgery
Arthur Gribensk, Andrew Schneider, Jared R. Gallaher, Trista S. Reid, Daniel G. Kindell, Anthony G. Charles, Lauren A. Raff
Summary: This study retrospectively examined the long-term outcomes of 24 COVID-19 patients after receiving extracorporeal membrane oxygenation (ECMO) treatment. The results showed that ECMO therapy had positive effects on the condition of COVID-19 patients and preserved their quality of life.
Article
Clinical Neurology
Edilberto Amorim, Marcos S. Firme, Wei-Long Zheng, Kenneth T. Shelton, Oluwaseun Akeju, Gaston Cudemus, Raz Yuval, M. Brandon Westover
Summary: This study retrospectively reviewed ECMO patients from 2011-2018 in a university-affiliated academic hospital, and found that seizures and ictal-interictal continuum patterns are relatively common during ECMO, but their association with in-hospital mortality and poor neurological outcomes is not significant.
CLINICAL NEUROPHYSIOLOGY
(2022)
Article
Multidisciplinary Sciences
Axelle Cusanno, Nadia Aissaoui, Vincent Minville, Jean Porterie, Caroline Biendel, Kim Volle, Laure Crognier, Jean-Marie Conil, Clement Delmas
Summary: Predictors of weaning failure during veno-arterial extracorporeal membrane oxygenation (VA ECMO) were evaluated in this study. Factors such as pre-existing ischemic heart disease, low left ventricular ejection fraction, low systolic blood pressure after the weaning test, and prolonged ECMO support were found to be predictors of weaning failure. Clinical and echocardiographic criteria can help increase the success rate of weaning.
SCIENTIFIC REPORTS
(2022)
Article
Engineering, Chemical
Zhuomin Jiang, Bao Tran Duy Nguyen, JeongHyeon Seo, Changgi Hong, Dongwoo Kim, Suhyun Ryu, Sohui Lee, Gyubok Lee, Young Hoon Cho, Jeong F. Kim, Kangwon Lee
Summary: This work developed a superhydrophobic membrane to improve the wetting resistance and long-term fouling of the ECMO membrane. A hydrophobic biocompatible PCL electrospun nanofiber membrane was fabricated and coated with PDMS to enhance hydrophobicity. The results suggest that the developed membrane has potential for application in ECMO membranes.
JOURNAL OF MEMBRANE SCIENCE
(2023)
Article
Pediatrics
Lisa S. Le, John P. Kinsella, Jason Gien, Benjamin S. Frank
Summary: We analyzed postnatal echocardiograms of 62 infants with congenital diaphragmatic hernia born between 2014 and 2020. Left and right ventricular dysfunction on day 0 showed high sensitivity, while persistent dysfunction on day 2 was specific for the need for extracorporeal membrane oxygenation. Biventricular dysfunction had the strongest association with extracorporeal membrane oxygenation. Serial echocardiography can provide prognosis information for congenital diaphragmatic hernia.
JOURNAL OF PEDIATRICS
(2023)
Article
Cardiac & Cardiovascular Systems
Arash Mehdiani, Moritz Benjamin Immohr, Charlotte Boettger, Hannan Dalyanoglu, Daniel Scheiber, Ralf Westenfeld, Hug Aubin, Payam Akhyari, Diyar Saeed, Artur Lichtenberg, Udo Boeken
Summary: This study compared the efficacy of peripheral cannulation and central cannulation in patients undergoing heart transplantation with extracorporeal life support. The results showed that both cannulation techniques had similar outcomes in terms of surgical complications, survival rates, and length of hospital stay.
THORACIC AND CARDIOVASCULAR SURGEON
(2021)
Article
Cardiac & Cardiovascular Systems
Darae Kim, Woo Jin Jang, Taek Kyu Park, Yang Hyun Cho, Jin-Oh Choi, Eun-Seok Jeon, Jeong Hoon Yang
Summary: Echocardiographic parameters during ECMO flow study may predict successful weaning from VA-ECMO. Improvement of lateral e' velocity and tricuspid annular S' velocity during ECMO flow study correlate with successful VA-ECMO weaning, suggesting a better representation of cardiac reserve than conventional echocardiographic parameters.
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
(2021)
Article
Biochemistry & Molecular Biology
Livia Provitera, Giacomo S. Amelio, Matteo Tripodi, Genny Raffaeli, Francesco Macchini, Ilaria Amodeo, Silvia Gulden, Valeria Cortesi, Francesca Manzoni, Gaia Cervellini, Andrea Tomaselli, Gabriele Zuanetti, Caterina Lonati, Michele Battistin, Shady Kamel, Valeria Parente, Valentina Pravata, Stefania Villa, Eduardo Villamor, Fabio Mosca, Giacomo Cavallaro
Summary: Extracorporeal membrane oxygenation (ECMO) is a lifesaving treatment for respiratory and cardiovascular failure, but it can induce a systemic inflammatory response syndrome and lead to endothelial dysfunction. This study found that ECMO exposure impairs coronary relaxation mediated by endothelium-derived nitric oxide (NO), but has no effect on thromboxane-induced contraction or sodium nitroprusside-induced relaxation. The response of smooth muscle cells to exogenous NO is also unaffected by ECMO exposure.
Article
Biochemistry & Molecular Biology
Lars Falk, Alexander Fletcher-Sandersjoo, Jan Hultman, Lars Mikael Broman
Summary: The study found that patients converted from VV to VA ECMO had a higher mortality rate and lower prognosis scores, especially those converted due to right ventricular failure. VA ECMO is recommended as the first choice for patients with respiratory failure and signs of circulatory impairment. Furthermore, pre-admission RESP score, daily echocardiography, and SOFA score trajectories may help in early identification of patients needing conversion therapy.
Meeting Abstract
Cardiac & Cardiovascular Systems
Marcus Henze, Robert Anderson, Fiona Wong, Robert Weiss, Abhay Divekar, David Meyerholz, Ferhaan Ahmad, Eric Green
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
(2017)
Meeting Abstract
Cardiac & Cardiovascular Systems
Deidra Ansah, Derek Hoyme, Abhay Divekar
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2017)
Meeting Abstract
Cardiac & Cardiovascular Systems
Natalie Behrle, Abhay Divekar
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2018)
Meeting Abstract
Cardiac & Cardiovascular Systems
Sarah Studyvin, Abhay Divekar
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2019)
Meeting Abstract
Cardiac & Cardiovascular Systems
Sarah Studyvin, Natalie Jayaram, Natalie Behrle, Hayley Hancock, Abhay Divekar
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2019)
Editorial Material
Cardiac & Cardiovascular Systems
Natalie Jayaram, Stephen Kaine, Abhay A. Divekar
JACC-CARDIOVASCULAR INTERVENTIONS
(2019)
Article
Cardiac & Cardiovascular Systems
Christopher Mathis, Ryan Romans, Abhay Divekar
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
(2020)
Article
Obstetrics & Gynecology
Abhay A. Divekar, Pisespong Patamasucon, Joshua S. Benjamin
Summary: This study highlights the possibility of COVID-19 associated MIS-C like disease in critically ill neonates born to mothers with COVID-19. IVIG treatment resulted in rapid clinical improvement, indicating the importance of high clinical suspicion and prompt intervention in such cases. Echocardiography played a critical role in diagnosis and management.
AMERICAN JOURNAL OF PERINATOLOGY
(2021)
Article
Pediatrics
Yousef Arar, Abhay Divekar, Stephen Clark, Tarique Hussain, Roby Sebastian, Mehar Hoda, Jamie King, Thomas M. Zellers, Surendranath R. Veeram Reddy
Summary: This article reviews the common applications of cross-sectional imaging in the management of congenital heart disease (CHD) and discusses its impact on procedural planning, success, and patient surveillance.
Review
Pediatrics
Abhay A. Divekar, Yousef M. Arar, Stephen Clark, Animesh Tandon, Thomas M. Zellers, Surendranath R. Veeram Reddy
Summary: Transcatheter device intervention has become the first line therapy for many congenital heart defects, replacing traditional cardiac surgery. Advanced imaging plays a crucial role in these procedures, and there is strong support from society and industry for CHD-specific device research and development. The regulatory framework for device approval is patient friendly.
Meeting Abstract
Cardiac & Cardiovascular Systems
Carlos L. del Rio, Aprajita Yadav, Neal Huang, Gail E. Geist, Yukie Ueyama, Brad L. Youngblood, Marc J. Evanchik, Eric Green, Abhay Divekar, Ferhaan Ahmad
Meeting Abstract
Cardiac & Cardiovascular Systems
Eric M. Green, David K. Meyerholz, Carlos del Rio, Lindsey M. Gifford, Frank Rohret, Jessica C. Sieren, Christopher Rogers, Abhay Divekar, Robert M. Weiss, Ferhaan Ahmad
Article
Cardiac & Cardiovascular Systems
Jess T. Randall, Osamah T. Aldoss, Ian H. Law, Abhay A. Divekar
ANNALS OF PEDIATRIC CARDIOLOGY
(2018)
Meeting Abstract
Cardiac & Cardiovascular Systems
Carlos L. del Rio, Marcus P. Henze, Fiona L. Wong, Marc J. Evanchik, Abhay Divekar, Lindsey M. Gifford, Ahmad Ferhaan, Eric M. Green
Meeting Abstract
Cardiac & Cardiovascular Systems
Eric M. Green, Robert M. Weiss, Abhay Divekar, Bartholomew Sadie R. Ingle, Marcus Henze, Raja Kawas, Lindsey Gifford, Melissa K. Davis, Frank Rohret, Daniel R. Thedens, Hector M. Rodriguez, Marc J. Evanchik, Robert L. Anderson, Jessica Sieren, Christopher S. Rogers, David K. Meyerholz, Ferhaan Ahmad
CIRCULATION RESEARCH
(2017)