Synthesis, biological evaluation and molecular docking studies of thiazole-based pyrrolidinones and isoindolinediones as anticonvulsant agents
出版年份 2015 全文链接
标题
Synthesis, biological evaluation and molecular docking studies of thiazole-based pyrrolidinones and isoindolinediones as anticonvulsant agents
作者
关键词
2-Aminothiazole, Anticonvulsants, Neurotoxicity, Molecular docking, X-ray crystallography
出版物
MEDICINAL CHEMISTRY RESEARCH
Volume 24, Issue 8, Pages 3194-3211
出版商
Springer Nature
发表日期
2015-04-27
DOI
10.1007/s00044-015-1371-3
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Anticonvulsant activity of pregabalin in the maximal electroshock-induced seizure assay in α2δ1 (R217A) and α2δ2 (R279A) mouse mutants
- (2014) Susan Lotarski et al. EPILEPSY RESEARCH
- Comparison between the effect of propofol and midazolam on picrotoxin-induced convulsions in rat
- (2014) Zuheir A. Hasan et al. PHYSIOLOGY & BEHAVIOR
- Novel analogues of chlormethiazole are neuroprotective in four cellular models of neurodegeneration by a mechanism with variable dependence on GABAAreceptor potentiation
- (2013) Lawren VandeVrede et al. BRITISH JOURNAL OF PHARMACOLOGY
- The historical evolution of, and the paradigms shifts in, the therapy of convulsive status epilepticus over the past 150 years
- (2013) Simon Shorvon EPILEPSIA
- Synthesis of some new 2-(3-pyridyl)-4,5-disubstituted thiazoles as potent antimicrobial agents
- (2013) Samir Bondock et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Imidazole Incorporated Semicarbazone Derivatives as a New Class of Anticonvulsants: Design, Synthesis and In-Vivo Screening
- (2013) Mohammad Amir et al. Medicinal Chemistry
- In-silico design, synthesis and evaluation of novel DNA-gyrase B inhibitors
- (2013) Umesh Shiroya et al. MEDICINAL CHEMISTRY RESEARCH
- Palladium-Catalyzed CH and CN Arylation of Aminothiazoles with Arylboronic Acids
- (2013) Takahiro N. Uehara et al. Asian Journal of Organic Chemistry
- Current position of phenobarbital in epilepsy and its future
- (2012) Martin J. Brodie et al. EPILEPSIA
- Minocycline- and tetracycline-class antibiotics are protective against partial seizures in vivo
- (2012) Doris D. Wang et al. EPILEPSY & BEHAVIOR
- Synthesis and antimicrobial activity of some new hydrazone-bridged thiazole-pyrrole derivatives
- (2012) Leyla Yurttaş et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Docking, synthesis, and pharmacological investigation of novel substituted thiazole derivatives as non-carboxylic, anti-inflammatory, and analgesic agents
- (2012) S. N. Thore et al. MEDICINAL CHEMISTRY RESEARCH
- γ-Amino butyric acid analogs as novel potent GABA-AT inhibitors: molecular docking, synthesis, and biological evaluation
- (2012) S. K. Bansal et al. MEDICINAL CHEMISTRY RESEARCH
- Molecular properties prediction and synthesis of novel 1,3,4-oxadiazole analogues as potent antimicrobial and antitubercular agents
- (2011) Mohamed Jawed Ahsan et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Conformationally restricted GABA analogs: from rigid carbocycles to cage hydrocarbons
- (2011) Igor A Levandovskiy et al. Future Medicinal Chemistry
- Selective GABA Transporter Inhibitors Tiagabine and EF1502 Exhibit Mechanistic Differences in Their Ability to Modulate the Ataxia and Anticonvulsant Action of the Extrasynaptic GABAA Receptor Agonist Gaboxadol
- (2011) K. K. Madsen et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Status epilepticus: Why, what, and how
- (2011) UK Misra et al. Journal of Postgraduate Medicine
- Docking-based virtual screening of Schiff’s bases of GABA: a prospective to novel GABA-AT inhibitors
- (2011) S. K. Bansal et al. MEDICINAL CHEMISTRY RESEARCH
- Synthesis, characterization, and pharmacological evaluation of new GABA analogs as potent anticonvulsant agents
- (2011) Naveen Yadav et al. MEDICINAL CHEMISTRY RESEARCH
- Thiazoles: having diverse biological activities
- (2011) Shiv Jee Kashyap et al. MEDICINAL CHEMISTRY RESEARCH
- Synthesis, Anthelmintic and Anti-inflammatory Activities of Some Novel Imidazothiazole Sulfides and Sulfones
- (2010) Nitinkumar S. Shetty et al. BULLETIN OF THE KOREAN CHEMICAL SOCIETY
- Antiepileptic Drug Interactions - Principles and Clinical Implications
- (2010) Svein I. Johannessen et al. Current Neuropharmacology
- Synthesis, anticonvulsant and toxicity screening of newer pyrimidine semicarbazone derivatives
- (2010) Ozair Alam et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- N’-[(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene] 2/4-substituted hydrazides: Synthesis and anticonvulsant activity
- (2010) Darpan Kaushik et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Design & synthesis of 2-(substituted aryloxy)-5-(substituted benzylidene)-3-phenyl-2,5-dihydro-1H-[1,2,4] triazin-6-one as potential anticonvulsant agents
- (2010) Darpan Kaushik et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Design and synthesis of 10-alkoxy-5, 6-dihydro-triazolo[4,3-d]benzo[f][1,4]oxazepine derivatives with anticonvulsant activity
- (2010) Xian-Qing Deng et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis and antimicrobial activity of some new thiazole, thiophene and pyrazole derivatives containing benzothiazole moiety
- (2010) Samir Bondock et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- ChemBioOffice Ultra 2010 Suite ChemBioOffice Ultra 2010 Suite . CambridgeSoft . 100 CambridgePark Drive, Cambridge, MA 02140 . www.cambridgesoft.com . See Web site for pricing information.
- (2010) Sean M. Kerwin JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Structure validation in chemical crystallography
- (2009) Anthony L. Spek ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Synthesis and antimicrobial activity evaluation of new 1,2,4-triazoles and 1,3,4-thiadiazoles bearing imidazo[2,1-b]thiazole moiety
- (2009) Nuray Ulusoy Güzeldemirci et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Docking of 1,4-Benzodiazepines in the 1/ 2 GABAA Receptor Modulator Site
- (2009) D. Berezhnoy et al. MOLECULAR PHARMACOLOGY
- Synthesis and preliminary evaluation of some substituted coumarins as anticonvulsant agents
- (2008) Kamelia M. Amin et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Design and synthesis of some thiazolyl and thiadiazolyl derivatives of antipyrine as potential non-acidic anti-inflammatory, analgesic and antimicrobial agents
- (2008) Sherif A.F. Rostom et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Antioxidant activity of an aminothiazole compound: Possible mechanisms
- (2008) Strayo De et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Structural Requirements for Eszopiclone and Zolpidem Binding to the γ-Aminobutyric Acid Type-A (GABAA) Receptor Are Different
- (2008) Susan M. Hanson et al. JOURNAL OF MEDICINAL CHEMISTRY
- Molecular modeling of ligand–receptor interactions in GABAC receptor
- (2008) Dmitry I. Osolodkin et al. JOURNAL OF MOLECULAR GRAPHICS & MODELLING
- Determination of lipophilicity of novel potential antituberculotic agents using HPLC on monolithic stationary phase and theoretical calculations
- (2008) Z. Mrkvičková et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started