Review
Medicine, General & Internal
Tao Wang, Jing-Yu (Benjamin) Tan, Xian-Liang Liu, Isabella Zhao
Summary: This study identified the barriers and enablers to implementing clinical practice guidelines (CPGs) recommendations in primary care. The findings suggest that policy-driven strategies should be developed to optimize resource allocation, promote integrated care models, establish well-coordinated multidisciplinary networks, increase technical support, encourage healthcare providers and patients' engagement, standardize guideline reporting, enhance education and training, and stimulate motivations to facilitate the uptake of CPGs recommendations in primary care.
Article
Multidisciplinary Sciences
Supachai Ekwattanakit, Chattree Hantaweepant, Archrob Khuhapinant, Noppadol Siritanaratkul, Vip Viprakasit
Summary: This study evaluated the real-world practical management of complications surveillance in thalassemia patients, finding significant differences in surveillance rates among different treating physician groups. The results call for immediate policy change to improve and standardize care for thalassemia patients in Thailand.
SCIENTIFIC REPORTS
(2021)
Article
Health Care Sciences & Services
Peter M. Yellowlees, Michelle Burke Parish, Alvaro D. Gonzalez, Steven R. Chan, Donald M. Hilty, Byung-Kwang Yoo, J. Paul Leigh, Robert M. McCarron, Lorin M. Scher, Andres F. Sciolla, Jay Shore, Glen Xiong, Katherine M. Soltero, Alice Fisher, Jeffrey R. Fine, Jennifer Bannister, Ana-Maria Iosif
Summary: This study aimed to compare the impact of asynchronous telepsychiatry (ATP) and synchronous telepsychiatry (STP) on clinical outcomes for primary care patients. Results showed that ATP did not outperform STP in clinician-rated primary outcomes, but both groups showed significant improvements in secondary outcomes. Dropout rates were higher than predicted.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Article
Psychology, Multidisciplinary
Lauren Marlotte, Alexandra Klomhaus, Roya Ijadi-Maghsoodi, Hilary Aralis, Patricia Lester, Kim Griffin Esperon, Sheryl Kataoka
Summary: Youth in under-resourced communities have higher social risk factors for mental health needs but less access to care. School-based mental health services are effective, but few have a family-centered approach which may benefit specific populations.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Medicine, General & Internal
Saja H. Almazrou, Hajar Almoajil, Sara Alghamdi, Ghadeer Althenyan, Abdulhadi Alqahtani, Yasser Sami Amer
Summary: This study identifies key barriers and facilitators to the implementation of clinical practice guidelines in the Middle East and North Africa (MENA) through a three-round Delphi study. The results show that the highest-ranked barriers are related to communications and available research and skills, while the most important facilitator is the availability of training courses for healthcare professionals.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Austyn Snowden, Jenny Young, Denis Roberge, Stefano Schipani, Esther Murray, Claude Richard, Marie-Therese Lussier, Craig White
Summary: This study is a blinded, parallel, multi-centre, randomised controlled trial (RCT) investigating the impact of incorporating holistic needs assessment (HNA) into consultations. The results showed that there were no significant differences in patient participation, shared decision making, or self-efficacy between the HNA group and the control group. However, consultations in the HNA group were longer. This study does not support using medical colleagues to facilitate HNA in outpatient settings.
Article
Chemistry, Medicinal
Vahdad Varzaghani, Masoomeh Sharifi, Reza Hajiaghaee, Sara Bagheri, Saeideh Momtaz, Zahra Tarassoli, Ali Razmi
Summary: This study aimed to evaluate the efficacy and safety of propolis as a complementary therapy for depressive disorder. The results showed that propolis could safely attenuate symptoms of moderate-severe depression, possibly due to its rich content of phenolic acids and flavonoids.
PHYTOTHERAPY RESEARCH
(2022)
Review
Medical Informatics
Dipak Kotecha, Folkert W. Asselbergs, Stephan Achenbach, Stefan D. Anker, Dan Atar, Colin Baigent, Amitava Banerjee, Birgit Beger, Gunnar Brobert, Barbara Casadei, Cinzia Ceccarelli, Martin R. Cowie, Filippo Crea, Maureen Cronin, Spiros Denaxas, Andrea Derix, Donna Fitzsimons, Martin Fredriksson, Chris P. Gale, Georgios Gkoutos, Wim Goettsch, Harry Hemingway, Martin Ingvar, Adrian Jonas, Robert Kazmierski, Susanne Logstrup, R. Thomas Lumbers, Thomas F. Luescher, Paul McGreavy, Ileana L. Pina, Lothar Roessig, Carl Steinbeisser, Mats Sundgren, Benoit Tyl, Ghislaine van Thiel, Kees van Bochove, Panos E. Vardas, Tiago Villanueva, Marilena Vrana, Wim Weber, Franz Weidinger, Stephan Windecker, Angela Wood, Diederick E. Grobbee
Summary: Big data plays a crucial role in advancing global clinical science for the betterment of patient lives. This article introduces the CODE-EHR framework as a minimum standards guideline for researchers and clinicians to improve study design and enhance transparency in research methods, aiming to facilitate robust and effective utilization of healthcare data.
LANCET DIGITAL HEALTH
(2022)
Article
Psychiatry
Ali Amad, Thomas Fovet
Summary: This article discusses the challenges in using rTMS to treat depression, including the interpretation of the evidence level of this technique and which patients are suitable for this treatment.
AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY
(2022)
Article
Multidisciplinary Sciences
Shayan Shirazian, Arlene M. M. Smaldone, Alan M. M. Jacobson, Melissa J. J. Fazzari, Katie Weinger
Summary: This pilot study aimed to determine the feasibility of delivering a simple behavioral-education intervention using cognitive behavioral strategies in HD patients with poor quality of life. The intervention led to modest, but non-significant, improvement in kidney disease quality of life scores. Participants had a positive impression of the intervention and suggested improvements.
Article
Education & Educational Research
Isabel del Cura-Gonzalez, Gloria Ariza-Cardiel, Elena Polentinos-Castro, Juan A. Lopez-Rodriguez, Teresa Sanz-Cuesta, Jaime Barrio-Cortes, Blanca Andreu-Ivorra, Ricardo Rodriguez-Barrientos, Jose F. Avila-Tomas, Elisa Gallego-Ruiz-de-Elvira, Cristina Lozano-Hernandez, Jesus Martin-Fernandez
Summary: This study evaluated the impact of a game-based educational strategy, e-EDUCAGUIA, on the decision-making skills of family medicine residents. The results showed that e-EDUCAGUIA had a positive effect on knowledge and skills in the short term, but dropout rates were high.
BMC MEDICAL EDUCATION
(2022)
Article
Oncology
Michelle Treasure, Barbara Daly, Shufen Cao, Pingfu Fu, Augustine Hong, Elizabeth Weinstein, Jessica Surdam, Neal J. Meropol, Afshin Dowlati
Summary: This study compared differences in study duration, symptom burden, adverse events, and quality of life between phase 1 clinical trial patients receiving structured palliative care versus usual supportive care. Results showed that structured palliative care was associated with longer study duration and improved quality of life for patients and caregivers, with fewer adverse events experienced in the palliative care group.
Editorial Material
Obstetrics & Gynecology
Charles Ameh, Fernando Althabe
Summary: Reducing the risk of death from PPH requires evidence-based care, innovations, and addressing demand and supply-side bottlenecks around quality, availability, and use of uterotonics.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2022)
Article
Biochemistry & Molecular Biology
Rainer Tan, Godfrey Kavishe, Lameck B. Luwanda, Alexandra V. Kulinkina, Sabine Renggli, Chacha Mangu, Geofrey Ashery, Margaret Jorram, Ibrahim Evans Mtebene, Peter Agrea, Humphrey Mhagama, Alan Vonlanthen, Vincent Faivre, Julien Thabard, Gillian Levine, Marie-Annick Le Pogam, Kristina Keitel, Patrick Taffe, Nyanda Ntinginya, Honorati Masanja, Valerie D'Acremont
Summary: A study in Tanzania found that implementing a decision support algorithm, ePOCT+, significantly reduced antibiotic prescriptions for children without impacting clinical outcomes.
Article
Medicine, General & Internal
Adam D. DeVore, Bradi B. Granger, Gregg C. Fonarow, Hussein R. Al-Khalidi, Nancy M. Albert, Eldrin F. Lewis, Javed Butler, Ileana L. Pina, Larry A. Allen, Clyde W. Yancy, Lauren B. Cooper, G. Michael Felker, Lisa A. Kaltenbach, A. Thomas McRae, David E. Lanfear, Robert W. Harrison, Maghee Disch, Dan Ariely, Julie M. Miller, Christopher B. Granger, Adrian F. Hernandez
Summary: This study compared the effect of a hospital and postdischarge quality improvement intervention with usual care on heart failure outcomes and care. The results showed no significant difference in time to first heart failure rehospitalization or death, or in change in a composite heart failure quality-of-care score between the two groups.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2021)
Review
Psychiatry
Moritz Koehnen, Mareike Dreier, Tharanya Seeralan, Levente Kriston, Martin Haerter, Harald Baumeister, Sarah Liebherz
Summary: This study aims to structure evidence on TBIs by considering different application areas and treatment characteristics in order to provide a comprehensive evidence base and identify research gaps in TBIs for diagnosed depression. The research has given little attention to studying TBIs for aftercare and for bridging waiting periods, highlighting the need for high quality studies in these areas. Additionally, future studies should use specific guidelines to systematically assess and report negative events associated with TBIs.
JMIR MENTAL HEALTH
(2021)
Article
Oncology
Sigrun Vehling, Anja Mehnert-Theuerkauf, Rebecca Philipp, Martin Harter, Klaus Kraywinkel, Ronny Kuhnert, Uwe Koch
Summary: The study showed that patients with cancer have significantly higher prevalence rates of mental disorders, especially mood disorders and mental disorders due to general medical conditions. Lower occurrence of anxiety disorders in cancer patients was unexpected and may be worth exploring in future research.
Article
Pharmacology & Pharmacy
Arnim Johannes Gaebler, Michelle Finner-Prevel, Sarah Lammertz, Sabrina Schaffrath, Patrick Eisner, Felix Stoehr, Erik Roecher, Lina Winkler, Peter Kaleta, Laura Lenzen, Marc Augustin, Jana Hovancakova, Lara Schwemmer, Eva Stormanns, Fatih Keskin, Frederik Hendricks, Michael Paulzen, Gerhard Grunder, Frank Schneider, Klaus Mathiak
Summary: There is a negative relationship between vitamin D and antipsychotic drug concentrations, specifically drugs primarily metabolized by CYP3A4. Vitamin D has a relieving effect on symptomatology but counteracts the blood levels of antipsychotics. Patients with higher vitamin D levels have a higher proportion of therapeutically insufficient drug concentrations of aripiprazole and quetiapine.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Martino Belvederi Murri, Luigi Grassi, Rosangela Caruso, Maria Giulia Nanni, Luigi Zerbinati, Sylke Andreas, Berta Ausin, Alessandra Canuto, Martin Haerter, Manuel Munoz Lopez, Kerstin Weber, Hans-Ulrich Wittchen, Jana Volkert, George S. Alexopoulos
Summary: Late-life depression presents with diverse and heterogeneous clinical features, which were identified in this study as eight symptom complexes through network psychopathology. The study found reciprocal interactions between different symptom complexes, providing potential targets for personalized treatment and biomarker research in late-life depression.
MOLECULAR PSYCHIATRY
(2022)
Article
Health Care Sciences & Services
Eva Christalle, Stefan Zeh, Pola Hahlweg, Levente Kriston, Martin Haerter, Jordis Zill, Isabelle Scholl
Summary: This study aimed to develop and select items for the Experienced Patient-Centeredness (EPAT) Questionnaire to assess patient-centered care from the perspective of adult patients with chronic diseases in Germany. The study used a mixed-method design and generated 125 items assessing 16 dimensions of patient-centered care. The EPAT questionnaire holds promise for evaluating patient-centered care in routine clinical practice and for research and quality improvement purposes.
HEALTH EXPECTATIONS
(2022)
Article
Clinical Neurology
Bernd R. Foerstner, Mira Tschorn, Nicolas Reinoso-Schiller, Lea Mascarell Maricic, Erik Roecher, Janos L. Kalman, Sanna Stroth, Annalina V. Mayer, Kristina Schwarz, Anna Kaiser, Andrea Pfennig, Andre Manook, Marcus Ising, Ingmar Heinig, Andre Pittig, Andreas Heinz, Klaus Mathiak, Thomas G. Schulze, Frank Schneider, Inge Kamp-Becker, Andreas Meyer-Lindenberg, Frank Padberg, Tobias Banaschewski, Michael Bauer, Rainer Rupprecht, Hans-Ulrich Wittchen, Michael A. Rapp
Summary: This study examined the relationship between self-report and behavioral assessments and the latent constructs of the RDoC framework in a large transnosological population. The findings suggest a universal latent structure spanning across known nosological entities, highlighting the importance of using existing measures to capture aspects of the RDoC matrix.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
(2023)
Article
Health Care Sciences & Services
Leonie Gerke, Soenke Ladwig, Franz Pauls, Manuel Trachsel, Martin Haerter, Yvonne Nestoriuc
Summary: This study describes a randomized controlled web-based trial to investigate the efficacy of a one-session optimized informed consent consultation. By providing information on the setting, efficacy, mechanisms, and negative effects of psychotherapy, the consultation can meet ethical and legal obligations and strengthen contributing factors to psychotherapy outcome.
JMIR RESEARCH PROTOCOLS
(2022)
Article
Multidisciplinary Sciences
Levente Kriston, Lea Schumacher, Pola Hahlweg, Martin Haerter, Isabelle Scholl
Summary: The study found that using the skills network approach allows for the prediction of observer-rated SDM competence from physicians' self-reported SDM skills. By constructing an SDM skills network for each physician and using network parameters, observer-rated SDM competence could be accurately predicted. It is important to note that patient assessments and input are also crucial for predicting physicians' SDM competence.
Article
Health Care Sciences & Services
Linda Baumbach, Marc Frese, Martin Haerter, Hans-Helmut Koenig, Andre Hajek
Summary: This study examined the association between patient satisfaction with physician- and nurse-related care and quality of life and self-rated health among inpatients in a German hospital. The results suggested that higher satisfaction with care was associated with better quality of life and self-rated health.
Article
Psychology, Clinical
Leonie Gerke, Franz Pauls, Soenke Ladwig, Sarah Liebherz, Klaus Michael Reininger, Levente Kriston, Manuel Trachsel, Martin Haerter, Yvonne Nestoriuc
Summary: Optimizing the informed consent consultation can effectively enhance treatment expectations and decision-making in psychotherapy, leading to improved treatment consent capacity and satisfaction. This research highlights the importance of informed consent in psychotherapy.
JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY
(2023)
Letter
Medicine, General & Internal
Levente Kriston, Sarah Liebherz, Moritz Koehnen
Article
Psychiatry
Hendrik Mueller, Linda T. Betz, Joseph Kambeitz, Peter Falkai, Wolfgang Gaebel, Andreas Heinz, Martin Hellmich, Georg Juckel, Martin Lambert, Andreas Meyer-Lindenberg, Frank Schneider, Michael Wagner, Mathias Zink, Joachim Klosterkotter, Andreas Bechdolf
Summary: By conducting a network analysis, we found that impairments in source monitoring and perspective-taking are the main interactions between predictive cognitive basic symptoms (BS) and attenuated positive symptoms (APS). Identifying bridge symptoms between these two symptom domains can enhance our understanding of the etiology of psychosis and potentially guide tailored clinical interventions.
Article
Health Care Sciences & Services
Kerem Boege, Carine Karnouk, Andreas Hoell, Mira Tschorn, Inge Kamp-Becker, Frank Padberg, Aline Ubleis, Alkomiet Hasan, Peter Falkai, Hans-Joachim Salize, Andreas Meyer-Lindenberg, Tobias Banaschewski, Frank Schneider, Ute Habel, Paul Plener, Eric Hahn, Maren Wiechers, Michael Strupf, Andrea Jobst, Sabina Millenet, Edgar Hoehne, Thorsten Sukale, Raphael Dinauer, Martin Schuster, Nassim Mehran, Franziska Kaiser, Stefanie Broecheler, Klaus Lieb, Andreas Heinz, Michael Rapp, Malek Bajbouj
Summary: This study investigated the effectiveness and cost-effectiveness of a Stepped Care and Collaborative Model in reducing depressive symptoms in refugee populations. The results showed that this model was more effective than routine care practices and provided a suitable approach for delivering mental health services.
LANCET REGIONAL HEALTH-EUROPE
(2022)
