期刊
INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN FLUIDS
卷 72, 期 8, 页码 895-911出版社
WILEY
DOI: 10.1002/fld.3764
关键词
erythrocyte; fictitious domain method; lattice Boltzmann method; fluid-structure interaction; parachute shape
类别
资金
- National Natural Science Foundation of China [10902098]
- Fundamental Research Funds of the Central Universities [2010QNA40107]
- U.S. Department of Energy (DOE) Office of Science
- Alexander von Humboldt Foundation
- DOE [DE-AC05-76RL01830]
To model red blood cell (RBC) deformation and multiple-cell interactions in flow, the recently developed technique derived from the lattice Boltzmann method and the distributed Lagrange multiplier/fictitious domain method is extended to employ the mesoscopic network model for simulations of RBCs in flow. The flow is simulated by the lattice Boltzmann method with an external force, while the network model is used for modeling RBC deformation. The fluid-RBC interactions are enforced by the Lagrange multiplier. To validate parameters of the RBC network model, stretching tests on both coarse and fine meshes are performed and compared with the corresponding experimental data. Furthermore, RBC deformation in pipe and shear flows is simulated, revealing the capacity of the current method for modeling RBC deformation in various flows. Moreover, hydrodynamic interactions between two RBCs are studied in pipe flow. Numerical results illustrate that the leading cell always has a larger flow velocity and deformation, while the following cells move slower and deform less.Copyright (c) 2013 John Wiley & Sons, Ltd.
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