期刊
INTERNATIONAL DAIRY JOURNAL
卷 21, 期 11, 页码 887-895出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.idairyj.2011.05.008
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资金
- Hero, S.A.
- Consolider Fun-C-Food [CSD 2007-00063]
- University of Valencia (V Segles - Empresa)
Sialic acid and gangliosides content and profiles were analyzed in infant formulae, whey protein concentrates and human milk. In infant formulae, N-acetylneuraminic (Neu5Ac) and N-glycolylneuraminic (Neu5Gc) acid ranged from 147.6-199.7 to 3.3-8.3 mg L-1, in whey protein concentrate from 1.6-2.4 g 100 g(-1) to 2.8-20.2 mg 100 g(-1) and in human milk from 299.9 to 2.1 mg L-1. Gangliosides ranged from 0.25 to 2.29 mg lipid-bound sialic acid L-1 in reconstituted infant formula, the main gangliosides being GD(3) (73.3-55.5%), GM(3) (3.5-36.6%) and GT(3) (1.4-14.1%) and O-acetyl-GD(3) (5.3-18.9%). In whey protein concentrates, 0.7-55.6 mg lipid-bound sialic acid 100 g(-1) were found with the profile 82.1-86.9% GD(3) and 1.8-2.5% GM(3). Human milk gave 2 mg lipid-bound sialic acid L-1, with the profile 97.4% GM(3) and 2.5% GD(3). Intakes of sialic acid and gangliosides are lower with infant formulae versus human milk, especially during the first stages of life. (C) 2011 Elsevier Ltd. All rights reserved.
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