Article
Agriculture, Multidisciplinary
Yumin Niu, Bin Wang, Runhui Yang, Yongning Wu, Yunfeng Zhao, Cuizhi Li, Jing Zhang, Yang Xing, Bing Shao
Summary: Based on breastmilk samples collected from 9 provinces in China in 2014, it was found that BPA was the predominant BP, followed by BPF and BPS. There were no differences in BPA, BPF, BPS, or total BP levels between urban and rural regions or northern and southern regions. The high contribution of BPF in breastmilk samples, accounting for over 20%, indicates the need for attention to BPA analogues.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Environmental Sciences
Xiaoying Lin, Xiaoling Wu, Xiangyu Li, Duo Zhang, Quanzhi Zheng, Jiayi Xu, Shaoyou Lu
Summary: This study investigated the levels of trace elements in Chinese infant food products and found limited research on the associated risks.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Immunology
Laura Dickinson, Stephen Walimbwa, Yashna Singh, Julian Kaboggoza, Kenneth Kintu, Mary Sihlangu, Julie-Anne Coombs, Thokozile R. Malaba, Josaphat Byamugisha, Henry Pertinez, Alieu Amara, Joshua Gini, Laura Else, Christie Heiberg, Eva Maria Hodel, Helen Reynolds, Landon Myer, Catriona Waitt, Saye Khoo, Mohammed Lamorde, Catherine Orrell
Summary: The study investigated dolutegravir pharmacokinetics in pregnant women with untreated HIV presenting in late pregnancy, showing the relationship between dolutegravir concentrations in maternal plasma, umbilical cord, and breast milk, as well as the duration of prophylaxis for infants post maternal dolutegravir cessation.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Environmental Sciences
Santosh Lamichhane, Heli Siljander, Daniel Duberg, Jarno Honkanen, Suvi M. Virtanen, Matej Oresic, Mikael Knip, Tuulia Hyotylainen
Summary: This study found that maternal exposure to PFAS affects the lipid composition of breast milk, which in turn has detrimental impacts on infant growth and intestinal health.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Environmental Sciences
Linda R. Macheka, Ovokeroye A. Abafe, Liziwe L. Mugivhisa, Joshua O. Olowoyo
Summary: This study investigated the presence and concentrations of per and polyfluoroalkyl substances (PFAS) in breast milk of nursing mothers from South Africa. The findings are important for understanding the potential health risks to infants.
Article
Environmental Sciences
Minhui Li, Minhua Xiao, Qinru Xiao, Yining Chen, Yichen Guo, Jing Sun, Rong Li, Chun Li, Zhou Zhu, Hongmei Qiu, Xihong Liu, Shaoyou Lu
Summary: The study found that perchlorate and chlorate are commonly present in breast milk, infant formula, baby supplementary food, and tap water in South China, but the levels of these chemicals in the sampled baby food are not expected to increase the risk of adverse health effects for infants. This is the first study to simultaneously investigate perchlorate and chlorate exposure in Chinese infants through food intake.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Environmental Sciences
Qun Gao, Yumin Niu, Bin Wang, Jiaying Liu, Yunfeng Zhao, Jing Zhang, Yang Wang, Bing Shao
Summary: This study in Hunan, China found BPA concentrations in breast milk samples from 149 lactating mothers, with different TDIs for infants and lactating mothers. The study revealed a temporal decline trend in BPA concentrations in breast milk.
ENVIRONMENTAL POLLUTION
(2021)
Article
Nutrition & Dietetics
Samira Karbasi, Malihe Mohamadian, Mohsen Naseri, Zahra Khorasanchi, Asghar Zarban, Afsane Bahrami, Gordon A. A. Ferns
Summary: This study found an association between maternal adherence to a Mediterranean diet and the total antioxidant capacity of breast milk and infant urine. Individuals with the highest Mediterranean diet scores had significantly higher levels of DPPH in breast milk and infant urine, as well as higher levels of protein and FRAP in breast milk, compared to those with the lowest scores. Furthermore, mothers with the highest diet scores had significantly lower levels of TG in breast milk.
Article
Nutrition & Dietetics
Reka A. Vass, Gabriella Kiss, Edward F. Bell, Robert D. Roghair, Attila Miseta, Jozsef Bodis, Simone Funke, Tibor Ertl
Summary: Pituitary hormones like prolactin and luteinizing hormone were found to be higher in breast milk from mothers of preterm infants compared to term infants. Infant formulas have higher total protein content but do not contain detectable levels of pituitary hormones.
Article
Environmental Sciences
Xuelei Chen, Xuezhen Zhao, Zhixiong Shi
Summary: The study investigated the occurrence of thirteen OPFRs in breast milk samples collected from Beijing mothers in 2018, revealing China as one of the most affected regions by OPFRs. Personal characteristics of mothers were found to impact the levels of certain OPFRs in breast milk, with most nursing infants' daily OPFR intake not raising significant health concerns. However, two OPFRs, TPhP and EHDPP, were noted to have higher estimated daily intakes than corresponding reference doses, potentially posing health risks.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Medicine, Research & Experimental
Karen de Jong, David Damoiseaux, Dick Pluim, Hilde Rosing, Jos H. Beijnen, Hans van Thienen, Thomas P. C. Dorlo, Alwin D. R. Huitema, Frederic Amant
Summary: This study reports on the use of nivolumab during lactation in a woman with metastasized melanoma. It found that nivolumab accumulates in breast milk over two consecutive cycles. However, further research is needed to determine the safety of breastfeeding during nivolumab therapy.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Review
Food Science & Technology
Jimena Rios, Viviana Valero-Jara, Samanta Thomas-Valdes
Summary: Exclusive breastfeeding is recommended during the first 6 months of life, with breast milk composition being influenced by maternal diet. Polyphenols and carotenoids present in breast milk have antioxidant activities and potential benefits for infants, with their content depending on maternal intake and various factors. Further research is needed to understand the relationship between these phytochemicals and development of infants.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Engineering, Environmental
Dan Luo, Yanan Pan, Lixi Zeng, Bibai Du, Juan Li, Surong Mei
Summary: Multiple BPS derivatives, including 2,4'-Bis(hydroxyphenyl)sulfone and 4-hydroxyphenyl 4-isoprooxyphenylsulfone, were identified in human breast milk samples from Chinese lactating women. The total concentrations of the detectable BPS derivatives were slightly lower than those of commonly used BPA analogues, with concentrations of 2,4-BPS found to be similar to BPS in human breast milk.
ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS
(2021)
Article
Multidisciplinary Sciences
Kaplan Betul, Ortabag Tulay, Bayramoglu Tepe Neslihan, Orkmez Mustafa, Tosun Nuran
Summary: This study found that reducing BPA exposure during pregnancy can be achieved through training, increasing knowledge can improve health status, and training greatly minimizes exposure-causing behaviors.
Article
Nutrition & Dietetics
Sofie Stampe, Magnus Leth-Moller, Eva Greibe, Elke Hoffmann-Lucke, Michael Pedersen, Per Ovesen
Summary: This study investigated the distribution of artificial sweeteners (ASs) in the plasma and breast milk of lactating women and found that all four types of ASs were present in both plasma and breast milk, suggesting that they can be transferred to offspring through breastfeeding.
Article
Environmental Sciences
Allison Kupsco, Haotian Wu, Antonia M. Calafat, Marianthi-Anna Kioumourtzoglou, Alejandra Cantoral, Marcela Tamayo-Ortiz, Ivan Pantic, Maria Luisa Pizano-Zarate, Emily Oken, Joseph M. Braun, Andrea L. Deierlein, Robert O. Wright, Martha M. Tellez-Rojo, Andrea A. Baccarelli, Allan C. Just
Summary: Prenatal concentrations of urinary DEHP metabolites, DiNP metabolites, and MCNP were associated with trajectories of child adiposity, while the total phthalate mixture showed no significant association with early life child adiposity.
ENVIRONMENTAL RESEARCH
(2022)
Article
Endocrinology & Metabolism
Jordan R. Kuiper, Joseph M. Braun, Antonia M. Calafat, Bruce P. Lanphear, Kim M. Cecil, Aimin Chen, Yingying Xu, Kimberly Yolton, Heidi J. Kalkwarf, Jessie P. Buckley
Summary: Pregnancy phthalate exposures were found to be positively associated with increased bone mineral density Z-scores in early adolescence, with different patterns of associations observed between males and females. Further research is needed to determine the long-term implications for skeletal health.
Article
Environmental Sciences
Paulina Jedynak, Jorg Tost, Antonia M. Calafat, Ekaterina Bourova-Flin, Lucile Broseus, Florence Busato, Anne Forhan, Barbara Heude, Milan Jakobi, Joel Schwartz, Remy Slama, Daniel Vaiman, Johanna Lepeule, Claire Philippat
Summary: This study is the first to describe genome-wide modifications of placental DNA methylation in association with pregnancy exposure to phthalates. The results suggest that exposure to phthalates could affect fetal development through epigenetic mechanisms. Several differentially methylated regions associated with phthalate exposure were identified.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Environmental Sciences
Jennifer J. Yland, Yu Zhang, Paige L. Williams, Vicente Mustieles, Stylianos Vagios, Irene Souter, Antonia M. Calafat, Russ Hauser, Carmen Messerlian
Summary: This study found that preconception and prenatal exposure to phthalates may increase the risk of preterm birth, particularly in late pregnancy, especially the DEHP metabolites. This suggests that these chemicals may have adverse effects on women's health and fetal development.
ENVIRONMENTAL POLLUTION
(2022)
Article
Environmental Sciences
Diana C. Pacyga, Diana K. Haggerty, Megan Nicol, Melissa Henning, Antonia M. Calafat, Joseph M. Braun, Susan L. Schantz, Rita S. Strakovsky
Summary: Conception season, enrollment year, and several sociodemographic/lifestyle factors were found to be associated with biomarker profiles of phthalates and their replacements in pregnant women.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Environmental Sciences
Ana E. Skomal, Jasen Zhang, Kun Yang, Jessica Yen, Xin Tu, Jose Suarez-Torres, Dolores Lopez-Paredes, Antonia M. Calafat, Maria Ospina, Danilo Martinez, Jose R. Suarez-Lopez
Summary: This study found that urinary organophosphate metabolites, especially at concentrations above the 80th percentile, were associated with lower AChE activity among adolescents. These findings highlight the importance of considering multiple constructs of pesticide exposure in epidemiological studies.
ENVIRONMENTAL RESEARCH
(2022)
Article
Environmental Sciences
Weili Yang, Joseph M. Braun, Ann M. Vuong, Zana Percy, Yingying Xu, Changchun Xie, Ranjan Deka, Antonia M. Calafat, Maria Ospina, Erika Werner, Kimberly Yolton, Kim M. Cecil, Bruce P. Lanphear, Aimin Chen
Summary: This study found that maternal exposure to organophosphate esters (OPEs) may be associated with increased blood pressure during pregnancy and hypertensive disorders of pregnancy (HDP), particularly with the concentrations of diphenyl phosphate (DPHP) and bis(2-chloroethyl) phosphate (BCEP) showing stronger correlations with elevated blood pressure. Di-n-butyl phosphate (DNBP) concentrations were also associated with HDP, albeit with borderline significance.
ENVIRONMENTAL RESEARCH
(2022)
Article
Public, Environmental & Occupational Health
Seth McCormick, John E. Snawder, I-Chen Chen, Jonathan Slone, Antonia M. Calafat, Yuesong Wang, Lei Meng, Marissa Alexander-Scott, Michael Breitenstein, Belinda Johnson, Juliana Meadows, Cheryl Fairfield Estill
Summary: This study investigated the occupational exposure levels of PAHs among RCTS workers, finding that their air and skin concentrations were significantly higher than previous levels for asphalt workers, further confirming the potential risks associated with PAH exposure.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2022)
Article
Environmental Sciences
Lidia Minguez-Alarcon, Paige L. Williams, Tamarra James-Todd, Irene Souter, Jennifer B. Ford, Kathryn M. Rexrode, Antonia M. Calafat, Russ Hauser, Jorge E. Chavarro
Summary: This study examined the association between urinary concentrations of phthalate and phthalate replacement metabolites and lipid biomarker levels among pregnant women. The findings suggest that certain phthalate and phthalate replacement metabolite concentrations are associated with lipid levels in these women, with higher concentrations linked to higher lipid levels in some biomarkers and lower concentrations associated with lower lipid levels in others.
Article
Public, Environmental & Occupational Health
Jefferey L. Burgess, Julia M. Fisher, Amy Nematollahi, Alesia M. Jung, Miriam M. Calkins, Judith M. Graber, Casey C. Grant, Shawn C. Beitel, Sally R. Littau, John J. Gulotta, Darin D. Wallentine, R. Jeffrey Hughes, Charles Popp, Antonia M. Calafat, Julianne C. Botelho, Alissa D. Coleman, Natasha Schaefer-Solle, Paola Louzado-Feliciano, Simi O. Oduwole, Alberto J. Caban-Martinez
Summary: This study compared serum PFAS concentrations in firefighters from multiple fire departments with a general population sample. The results showed elevated concentrations of several PFAS in firefighters from four departments.
AMERICAN JOURNAL OF INDUSTRIAL MEDICINE
(2023)
Article
Environmental Sciences
Samantha Schildroth, Lauren A. Wise, Amelia K. Wesselink, Traci N. Bethea, Victoria Fruh, Kyla W. Taylor, Antonia M. Calafat, Donna D. Baird, Birgit Claus Henn
Summary: This study found that personal care product use, diet, and contraceptive measures may be the main sources of exposure to multiple non-persistent endocrine disrupting chemicals among reproductive-aged Black women.
Article
Peripheral Vascular Disease
Ning Ding, Carrie A. Karvonen-Gutierrez, Bhramar Mukherjee, Antonia M. Calafat, Sioban D. Harlow, Sung Kyun Park
Summary: The study revealed positive associations between several PFAS and incident hypertension, suggesting that PFAS might be an underappreciated contributing factor to women's cardiovascular disease risk.
Article
Environmental Sciences
Lidia Minguez-Alarcon, Lisa Frueh, Paige L. Williams, Tamarra James-Todd, Irene Souter, Jennifer B. Ford, Kathryn M. Rexrode, Antonia M. Calafat, Russ Hauser, Jorge E. Chavarro
Summary: This study investigates the association between urinary phenol concentrations and serum lipid levels in pregnant women. The results suggest that pregnant women with higher concentrations of urinary propylparaben and bisphenol A have higher levels of total cholesterol, non-HDL cholesterol, and LDL cholesterol in their serum.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Pediatrics
Barrett M. Welch, Alexander P. Keil, Jessie P. Buckley, Antonia M. Calafat, Kate E. Christenbury, Stephanie M. Engel, Katie M. O'Brien, Emma M. Rosen, Tamarra James-Todd, Ami R. Zota, Kelly K. Ferguson
Summary: A large study conducted in the US found that phthalate exposure during pregnancy may increase the odds of preterm birth. Reducing the concentration of phthalate metabolites could potentially prevent preterm births.
Meeting Abstract
Obstetrics & Gynecology
Barrett M. Welch, Alexander P. Keil, Jessie P. Buckley, Antonia M. Calafat, Kate E. Christenbury, Stephanie M. Engel, Katie M. O'Brien, M. Rosen Rosen, Kelly K. Ferugson
REPRODUCTIVE SCIENCES
(2022)
