期刊
INTERNAL MEDICINE
卷 48, 期 17, 页码 1535-1539出版社
JAPAN SOC INTERNAL MEDICINE
DOI: 10.2169/internalmedicine.48.2370
关键词
Brugada syndrome; antidepressant
We describe a case of Brugada syndrome, in which recurrent syncope with convulsive seizures was induced after antidepressant treatment. The patient had been treated With five kinds of psychotropic drugs, The twelve-lead ECG after the syncope exhibited an RSR'-pattern in the precordial leads, however, a coved type ST-segment elevation was induced by a pilsicainide test. Although ventricular fibrillation was not induced in the electrophysiologic study, an TCD implantation was considered as the recommended therapy since Brugada syndrome unmasked by antidepressants could not be ruled out. The possible contribution of antidepressants to Brugada type ST-segment changes is discussed.
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