期刊
INTERNAL MEDICINE
卷 48, 期 8, 页码 607-610出版社
JAPAN SOC INTERNAL MEDICINE
DOI: 10.2169/internalmedicine.48.1897
关键词
GH; ACTH; hypothalamus; pituitary; hypopituitarism; glucocorticoid
资金
- Ministry of Health, Labour, and Welfare of Japan
- Ministry of Education, Science and Culture of Japan [18591014]
Growth hormone (GH) deficiency is transient in most cases of adrenocorticotropin (ACTH) deficiency, while deficiency of both selective ACTH and GH in adults, as in the present case, is rare among hypopituitarism cases. In this patient, one year after hydrocortisone replacement for ACTH deficiency, data on GH secretion by insulin tolerance test and GH-releasing peptide-2 injection showed a partial improvement, but still there was lack of an adequate response. We consider that the patient had the deficiency of both selective GH and ACTH. Therefore, careful monitoring of GH function after the glucocorticoid replacement is required in cases of ACTH deficiency.
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