Article
Medicine, General & Internal
Lei Li, Zhenning Liu
Summary: Tetanus is a rapidly progressive infection that can lead to various complications, including rare rhabdomyolysis with acute anuria renal failure. Treatment of tetanus requires timely control of muscle spasms, appropriate blood purification therapy, and immunoglobulin treatment.
Article
Endocrinology & Metabolism
Julio A. Chirinos, Patricio Lopez-Jaramillo, Evangelos J. Giamarellos-Bourboulis, Gonzalo H. Davila-del-Carpio, Abdul Rahman Bizri, Jaime F. Andrade-Villanueva, Oday Salman, Carlos Cure-Cure, Nelson R. Rosado-Santander, Mario P. Cornejo Giraldo, Luz A. Gonzalez-Hernandez, Rima Moghnieh, Rapti Angeliki, Maria E. Cruz Saldarriaga, Marcos Pariona, Carola Medina, Ioannis Dimitroulis, Charalambos Vlachopoulos, Corina Gutierrez, Juan E. Rodriguez-Mori, Edgar Gomez-Laiton, Rosa Cotrina Pereyra, Jorge Luis Ravelo Hernandez, Hugo Arbanil, Jose Accini-Mendoza, Maritza Perez-Mayorga, Charalampos Milionis, Garyfallia Poulakou, Gregorio Sanchez, Renzo Valdivia-Vega, Mirko Villavicencio-Carranza, Ricardo J. Ayala-Garcia, Carlos A. Castro-Callirgos, Rosa M. Alfaro Carrasco, Willy Garrido Lecca Danos, Tiffany Sharkoski, Katherine Greene, Bianca Pourmussa, Candy Greczylo, Juan Ortega-Legaspi, Douglas Jacoby, Jesse Chittams, Paraskevi Katsaounou, Zoi Alexiou, Styliani Sympardi, Nancy K. Sweitzer, Mary Putt, Jordana B. Cohen
Summary: Fenofibrate has no significant effect on clinically relevant outcomes in patients with COVID-19.
Review
Virology
Yukako Matsuki, Takaaki Sugihara, Takuya Kihara, Tatsuru Kawakami, Tsuyoshi Kitaura, Tomoaki Takata, Takakazu Nagahara, Kai Fujita, Masayuki Hirai, Masaru Kato, Koichiro Kawaguchi, Hajime Isomoto
Summary: COVID-19 is not limited to respiratory involvement and can lead to multiorgan failure. This case report highlights the development of acute liver failure and rhabdomyolysis in a COVID-19 patient, emphasizing the significance of COVID-19 in the occurrence of multiorgan failure.
Article
Cell Biology
Tianshi Sun, Qing Liu, Yifan Wang, Youwen Deng, Dongshan Zhang
Summary: Our study found that MBD2 plays a role in RM-induced AKI by activating Tox4 and preventing promoter methylation. This suggests that MBD2 could be a potential target for treating RM-associated AKI.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
(2021)
Article
Medicine, Research & Experimental
Seyed Ali Hoseini Azad, Mohammad Moshiri, Ali Roohbakhsh, Abolfazl Shakeri, Ashkan Fatemi Shandiz, Leila Etemad
Summary: This study evaluated the effect of montmorillonite on an acute kidney injury model in rats. The results showed that montmorillonite can decrease levels of urea, creatinine, potassium, and calcium, and reduce kidney damage. Montmorillonite has high ion exchange capacity and low side effects, making it a potentially low-cost and effective treatment option for acute kidney injury.
IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES
(2023)
Review
Biochemistry & Molecular Biology
Piotr Lagosz, Jan Biegus, Szymon Urban, Robert Zymlinski
Summary: Cardiorenal syndrome (CRS) is a complex and heterogeneous spectrum of symptoms that has posed challenges for cardiologists for many years. The coexistence of heart failure (HF) and deteriorated renal function adds to these challenges and is a strong predictor of poor outcomes. However, with the development of new renal assessment methods, we now have the opportunity to treat CRS more effectively than ever before. This review focuses on explaining the pathophysiology, recent advances, and current practices of monitoring renal function in patients with acute CRS, aiming to improve patient care and guide treatment strategies.
Review
Pharmacology & Pharmacy
Abhi Dutta, Shubham Saha, Ajay Bahl, Anupam Mittal, Trayambak Basak
Summary: Cardiorenal syndrome is a broad spectrum disorder affecting the heart and kidneys. India has a high burden of acute cardiorenal syndrome, with 46.1% of patients diagnosed in India. Acute cardiorenal syndrome involves sudden kidney deterioration in acute heart failure patients. The pathophysiology includes hyperactivation of the sympathetic nervous system and the renin-angiotensin-aldosterone system. Complications increase the risk of mortality, making it a global healthcare burden. Current biomarkers have limitations in early detection, highlighting the need for novel proteomic biomarkers to prevent progression.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Urology & Nephrology
Maxime Desgrouas, Thierry Boulain
Summary: There is a significant association between paracetamol exposure and reduced incidence of RRT among patients with rhabdomyolysis, as shown by the study.
JOURNAL OF NEPHROLOGY
(2021)
Article
Environmental Sciences
Ghada N. El-Sarnagawy, Mona M. Ghonem, Marwa A. Abdelhameid, Omaima M. Ali, Asmaa M. Ismail, Doaa M. El Shehaby
Summary: This study aimed to evaluate the early predictors of adverse outcomes in acute PPD poisoning, with a focus on the accuracy of REMS and SOFA scores. The retrospective cohort study included all acute PPD-poisoned patients admitted to three Egyptian emergency hospitals. The results showed that REMS had the highest accuracy in predicting mortality, while the SOFA score was more practical for anticipating complications.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Cardiac & Cardiovascular Systems
Raffaele Bugiardini, Jinsung Yoon, Guiomar Mendieta, Sasko Kedev, Marija Zdravkovic, Zorana Vasiljevic, Davor Milicic, Olivia Manfrini, Mihaela van der Schaar, Chris P. Gale, Maria Bergami, Lina Badimon, Edina Cenko
Summary: This study found that previous statin therapy is associated with a reduced risk of AHF and improved survival from AHF in ACS patients.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Medicine, General & Internal
Manoj Kumar, Maasila Arcot Thanjan, Natarajan Gopalakrishnan, Dhanapriya Jeyachandran, Dineshkumar Thanigachalam, Sakthirajan Ramanathan
Summary: Snake bite-induced AKI in India has a 20.7% incidence rate, with mortality associated with shock and thrombocytopenia. Long-term adverse renal outcomes occurred in 48.8% of patients, with older age and longer duration on dialysis significantly linked to these outcomes.
POSTGRADUATE MEDICAL JOURNAL
(2022)
Article
Acoustics
Ping Zhao, Qiuyang LI, Shuo Wang, Yiru Wang, Jianing Zhu, Lianhua Zhu, Jie Tang, Yukun Luo
Summary: The aim of this study was to evaluate renal perfusion changes in rats with acute kidney injury induced by rhabdomyolysis using contrast-enhanced ultrasound (CEUS) and quantitative parameters. The results showed significant differences in CEUS quantitative parameters between the experimental and control groups, indicating that CEUS has diagnostic value for rhabdomyolysis-induced acute kidney injury.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2022)
Article
Medicine, General & Internal
Chao Liu, Kun Chi, Xiaodong Geng, Quan Hong, Zhi Mao, Qi Huang, Dong Liu, Yiqin Wang, Ying Zhang, Feihu Zhou, Guangyan Cai, Xiangmei Chen, Xuefeng Sun
Summary: The study showed that exogenous biological renal support through parabiosis improved renal recovery in RM-induced AKI mice by suppressing the complement system, reducing oxidative stress, inflammation, and cell death, and promoting tubular cell proliferation. The results indicate the potential of bioartificial kidneys in treating RM-induced AKI.
FRONTIERS IN MEDICINE
(2021)
Article
Pediatrics
Louise Pigeaud, Loes de Veld, Nico van der Lely
Summary: This study explores the prevalence of creatinine kinase elevation in Dutch adolescents with acute alcohol intoxication. Data from a major hospital in Delft, the Netherlands, were collected from 2008 to 2021. Among the 495 adolescents included in the study, 60% had elevated creatinine kinase levels, with a mean of 254 U/I. Rhabdomyolysis was present in 4.4% of cases and higher blood alcohol concentration was associated with higher creatinine kinase levels.
EUROPEAN JOURNAL OF PEDIATRICS
(2023)
Article
Pharmacology & Pharmacy
Rhonda M. Cooper-DeHoff, Mikko Niemi, Laura B. Ramsey, Jasmine A. Luzum, E. Katriina Tarkiainen, Robert J. Straka, Li Gong, Sony Tuteja, Russell A. Wilke, Mia Wadelius, Eric A. Larson, Dan M. Roden, Teri E. Klein, Sook Wah Yee, Ronald M. Krauss, Richard M. Turner, Latha Palaniappan, Andrea Gaedigk, Kathleen M. Giacomini, Kelly E. Caudle, Deepak Voora
Summary: Statins are commonly prescribed medications that reduce cholesterol and prevent cardiovascular disease. However, statin-associated musculoskeletal symptoms can affect patient adherence and long-term effectiveness. Genetic variations in SLCO1B1, ABCG2, and CYP2C9 genes have been identified to impact the metabolism and adverse events of statins. This study summarizes the literature supporting these associations and provides therapeutic recommendations based on genotypes to improve the safety, adherence, and effectiveness of statin therapy.
CLINICAL PHARMACOLOGY & THERAPEUTICS
(2022)
Article
Respiratory System
C. Dogan, A. Fidan, S. S. Comert, N. Kiral, B. Salepci, E. T. Parmaksiza, B. Caglayan
Article
Urology & Nephrology
Ergun Parmaksiz, Elif Torun Parmaksiz
INTERNATIONAL UROLOGY AND NEPHROLOGY
(2020)
Article
Clinical Neurology
Elif Torun Parmaksiz
Summary: A short-term daytime CPAP trial before the titration night may lead to longer and more efficient sleep on the titration night, as well as better CPAP adherence at one month follow-up for OSA patients.
SLEEP AND BREATHING
(2021)
Meeting Abstract
Clinical Neurology
E. Torun Parmaksiz, E. Parmaksiz
Article
Endocrinology & Metabolism
E. T. Parmaksiz, E. Parmaksiz
Summary: This study identified an association between severe obstructive sleep apnoea and increased HbA(1c) levels, suggesting it should be considered as a component of the metabolic syndrome.
DIABETES STOFFWECHSEL UND HERZ
(2021)
Article
Respiratory System
Banu Salepci, Sevda Ozdogan, Elif Cigdem Altunok, Tuba Naziroglu, Nesrin Kiral, Elif Torun Parmaksiz, Ali Fidan, Seda Beyhan Sagmen, Coskun Dogan, Sevda Sener Comert
Summary: This study aimed to compare the success rates of three different drug prescription policies for smoking cessation. The results showed that the self-payment medication group had significantly higher smoking cessation rates. Factors such as longer treatment duration, lower dependency score, and self-payment of medication were found to independently increase smoking cessation success.
TURKISH THORACIC JOURNAL
(2021)
Meeting Abstract
Respiratory System
Elif Torun Parmaksiz, Gizem Turkes, Gulten Aktin Gungor, Nesrin Kiral, Coskun Dogan, Sevda Comert
EUROPEAN RESPIRATORY JOURNAL
(2020)
Meeting Abstract
Respiratory System
Seda Beyhan Sagmen, Coskun Dogan, Sevda Comert, Nesrin Kiral, Elif Torun Parmaksiz, Ali Fidan, Nagehan Ozdemir Barisik, Sule Karabulut Gul
EUROPEAN RESPIRATORY JOURNAL
(2020)
Article
Respiratory System
Coskun Dogan, Nesrin Kiral, Elif Torun Parmaksiz, Ali Fidan, Benan Caglayan, Banu Salepci, Sevda Sener Comert
EURASIAN JOURNAL OF PULMONOLOGY
(2020)
Article
Respiratory System
Coskun Dogan, Sevda Sener Comert, Banu Salepci, Nesrin Kiral, Elif Torun Parmaksiz, Benan Caglayan
EURASIAN JOURNAL OF PULMONOLOGY
(2019)
Article
Respiratory System
Coskun Dogan, Nesrin Kiral, Elif Torun Parmaksiz, Omer Zengin, Benan Caglayan, Ali Fidan, Sevda Sener Comert, Banu Salepci, Seda Beyhan Sagmen
EURASIAN JOURNAL OF PULMONOLOGY
(2019)
Meeting Abstract
Respiratory System
Izolde Bouloukaki, Charalampos Mermigkis, Manolis Markakis, Athanasia Pataka, Paschalis Steiropoulos, Christina Ermidou, Joanna Alexaki, Stylianos Michelakis, Sophia Schiza
EUROPEAN RESPIRATORY JOURNAL
(2019)
Article
Hematology
Seda Beyhan Sagmen, Sevda Comert, Esra Turan Erkek, Aysun Kucukoz Uzun, Coskun Dogan, Guven Yilmaz, Nesrin Kiral, Ali Fidan, Cagla Yilmaz Haksal, Elif Torun Parmaksiz
ACTA HAEMATOLOGICA
(2019)
Article
Respiratory System
Coskun Dogan, Ali Fidan, Nesrin Kiral, Elif Torun Parmaksiz, Banu Salepci, Benan Caglayan, Sevda Sener Comert
EURASIAN JOURNAL OF PULMONOLOGY
(2019)
Article
Respiratory System
Coskun Dogan, Nesrin Kiral, Elif Torun Parmaksiz, Benan Caglayan, Seda Beyhan Sagmen, Banu Salepci, Ali Fidan, Sevda Sener Comert
SARCOIDOSIS VASCULITIS AND DIFFUSE LUNG DISEASES
(2019)