期刊
INTERNAL MEDICINE
卷 47, 期 19, 页码 1649-1654出版社
JAPAN SOC INTERNAL MEDICINE
DOI: 10.2169/internalmedicine.47.1269
关键词
colon cancer; rectal cancer; synchronous adenoma; distribution
Objective The incidence of colorectal cancer throughout the Republic of Korea has been rising over the last 25 years. The change in incidence is supposed to be due to the westernized life style. We evaluated the anatomical distribution of colorectal cancer and the properties of synchronous adenomatous polyps in the Korean population which were known to be different from those in Western countries. Materials and Methods From January 1997 to December 2006, 896 cases of colorectal cancer were reviewed retrospectively. Results A total of 25.1% were proximally located cancer with a modest female predominance (odds ratio 1.5). Synchronous adenomatous lesions were accompanied in 31.9% of all colorectal cancer cases. In the distal colorectal cancer patients, 18.8% had proximally located synchronous adenomas. In those with proximal colon cancer, only 20.5% of patients had distally located adenomas. The likelihood of a proximal colon cancer without distal sentinel lesions was higher in females (odds ratio 3.0). Conclusion There has been a steep rise in the incidence of colorectal cancer in Korea and distal colon cancer is more prevalent than in Western countries. However, as over 20% of proximal colon cancers can exist without distal colonic synchronous or sentinel lesions, a total colonoscopic examination should be considered first in surveillance.
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