Article
Environmental Sciences
Wei Yuan, Zhaopeng Xu, You Wei, Wuting Lu, Kun Jia, Jing Guo, Yunlong Meng, Yuyang Peng, Zhanfeng Wu, Zulin Zhu, Fei Ma, Fenghua Wei, Guiyou Tian, Zhou Liu, Qiang Luo, Jinze Ma, Hao Zhang, Wenjin Liu, Huiqiang Lu
Summary: Exposure to Sulfometuron methyl (SM) led to toxicity in zebrafish early developmental stages, affecting development, immune system, locomotor behavior, oxidative stress, and cell apoptosis.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Environmental Sciences
Tao Huang, Christopher L. Souders, Shuo Wang, Jade Ganter, Jia He, Yuan H. Zhao, Hongguang Cheng, Christopher J. Martyniuk
Summary: Fenamidone negatively affects the development of zebrafish embryos, causing a delay in hatching time and morphological deformities. It also significantly reduces oxygen consumption rates of embryos and decreases Sod2 mRNA levels in larval fish. Additionally, exposure to fenamidone leads to decreased locomotor activity in zebrafish larvae.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Environmental Sciences
Mario Schuster, Sophie Constance Bornhoft, Rainer Lueg, Yassin Denis Bouzzine
Summary: This research examines the impact of the Fridays for Future movement on the European and U.S. stock markets. Through an event study on stocks listed in the Stoxx Europe 600 and S&P 500, the study analyzes the price reactions during the Global Climate Strikes 1-11. The findings reveal that climate activism significantly influenced stock valuation and that superior environmental performance is beneficial when climate activism receives high public attention. The study also highlights the differences in market reactions between Europe and the U.S. and contributes to the literature by showing that investors react not only to primary stakeholder events but also to secondary stakeholder pressure.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2023)
Article
Biochemistry & Molecular Biology
Lilah Glazer, Caroline H. Brennan
Summary: Developmental exposure to different doses of MeHg in zebrafish led to increased anxiety-related responses, impaired locomotor activity, and disrupted expression of neural stress-response genes at both larval and adult stages. The study provides insights into dose-dependent differences in exposure outcomes and potential mechanisms underlying these effects over the lifetime of exposed individuals.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Environmental Sciences
Yinan Chai, Donglai Sheng, Xiaowei Ji, Yanlong Meng, Feihao Shen, Rui He, Runjia Ma, Yuying Wang
Summary: Exposure to AO2246 causes developmental and neurobehavioral toxicity in zebrafish larvae, leading to disturbances in neuronal activity and neurological disorders, ultimately impairing the locomotor behavior of zebrafish larvae.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Min Xia, Xuedong Wang, Jiaqi Xu, Qiuhui Qian, Ming Gao, Huili Wang
Summary: The study found that TCPP exposure had negative effects on zebrafish neurodevelopment and behavior, including decreased hatching rates, increased malformation rates, abnormal behaviors, and defects in neural cell structure. TCPP exposure also impacted adult zebrafish's social behavior, cognitive function, and nerve-related gene expression, leading to anxiety, panic, and reduced learning ability.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Environmental Sciences
Rebecca von Hellfeld, Christoph Gade, Lisa Baumann, Marcel Leist, Thomas Braunbeck
Summary: In order to determine neurotoxicity, new methods are being validated, including both in vitro and in vivo tests. One of the alternative test models attracting attention is the zebrafish embryo, specifically for assessing behavioral endpoints related to neurotoxicity during early development stages. This study investigated the sensitivity of the coiling assay, a method to assess random movement development, to different neurotoxicants with various modes of action.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Neurosciences
Marta Barenys, Shami Alvarez, Ariadna Santamaria, Elisabet Teixido, Jesus Gomez-Catalan
Summary: The study evaluated the developmental neurotoxic effects of MDMA in zebrafish embryos, finding that under specific experimental conditions, adverse neuromotor outcomes associated with MDMA prenatal exposure in humans can be reproduced in the zebrafish model. This opens the door for future mechanistic investigations to better understand the Adverse Outcome Pathway linked to MDMA prenatal exposure.
Article
Green & Sustainable Science & Technology
Kexiang Hu, Avik Sinha, Zhixiong Tan, Muhammad Ibrahim Shah, Shujaat Abbas
Summary: OECD countries have failed to fulfill their obligations towards the implementation of SDG 7 and SDG 13, which is a major constraint for global progress on curbing GHG emissions and mitigating climate change. The focus of COP26 was to explore policy options for a sustainable transition from fossil fuels to clean renewables. This study analyzes the impact of innovation in environmental technology and various policy regimes on energy transition in OECD countries.
RENEWABLE & SUSTAINABLE ENERGY REVIEWS
(2022)
Article
Medicine, Research & Experimental
Rebecca von Hellfeld, Viktoriia Ovcharova, Samantha Bevan, Maria-Agapi Lazaridi, Caroline Bauch, Paul Walker, Susanne Hougaard Bennekou, Anna Forsby, Thomas Braunbeck
Summary: The demand for reliable and sensitive (developmental) neurotoxicity testing of chemicals is increasing. However, the limitations of current mammalian test systems have led to the need for alternative models. This study evaluated the effects of neonicotinoids on zebrafish embryo development and behavior and found that the behavioral changes observed in the zebrafish were consistent with findings from mammalian studies. As a result, zebrafish embryo behavior testing could be integrated into future tiered testing schemes.
ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION
(2022)
Review
Plant Sciences
Dong-Hwan Kim
Summary: Polycomb repressive complexes (PRCs) are crucial for the growth and development of eukaryotes, with conserved components among most eukaryotes. The study of PRCs' gene silencing in plants has contributed to the understanding of the epigenetic control of developmental programs. This review provides current knowledge on PcG-mediated gene regulation, focusing on its role in various aspects of plant development and the molecular mechanisms involved, specifically in Arabidopsis plants.
JOURNAL OF PLANT BIOLOGY
(2023)
Article
Cell Biology
Jia Song, Yao Lu, Xiaoxia Cheng, Chuang Shi, Qiyong Lou, Xia Jin, Jiangyan He, Gang Zhai, Zhan Yin
Summary: The study demonstrated the critical role of TSH function in promoting zebrafish LTJT and SSC formation, as well as the essentiality of elevated TSH levels for goiter appearance in zebrafish.
Article
Biology
Frank Seebacher, Stephanie M. Bamford, Amelie Le Roy
Summary: Each parent can impact offspring phenotype through zygote provisioning or sex-specific DNA methylation. Transgenerational plasticity may depend on the environmental conditions experienced by each parent. In a factorial experiment using guppies, we found that the thermal background of mothers and fathers influenced mass, length, and thermal performance of sons and daughters. Offspring sex played a significant role in most traits. The study showed that parental thermal variation can modify offspring phenotype, highlighting the importance of considering the thermal background of each parent.
JOURNAL OF EXPERIMENTAL BIOLOGY
(2023)
Article
Hematology
Christopher B. Mahony, Pietro Cacialli, Corentin Pasche, Rui Monteiro, Savvas N. Savvides, Julien Y. Bertrand
Summary: The study found that the ECM component haplalb in zebrafish embryos plays a crucial role in the specification of HSPCs, and the gene kitigb related to the ECM also plays a key role in determining HSPCs.
Article
Neurosciences
Magda Carvalho Henriques, Ines Carvalho, Catia Santos, Maria Teresa Herdeiro, Margarida Fardilha, Maria Dimitriou Pavlaki, Susana Loureiro
Summary: This study investigated the effects of mercury exposure on zebrafish embryo-larvae at both individual and biochemical levels. The results showed that mercury exposure resulted in developmental abnormalities and behavioral changes in zebrafish embryo-larvae. The alterations in enzyme activity and protein phosphatase expression may be involved in the mechanisms underlying these effects.
NEUROTOXICOLOGY AND TERATOLOGY
(2023)