Article
Biochemistry & Molecular Biology
Thomas Desvignes, Iliana Bista, Karina Herrera, Audrey Landes, John H. Postlethwait
Summary: The expression of multiple hemoglobin isoforms helps species adapt to different conditions. Antarctic notothenioid fishes have fewer hemoglobin isoforms with lower affinity for oxygen. Adaptation to frigid conditions shaped hemoglobin gene evolution in Antarctic notothenioids, and hemoglobin gene expression undergoes changes in these fish.
MOLECULAR BIOLOGY AND EVOLUTION
(2023)
Article
Anatomy & Morphology
Amir M. Ashique, Oghenevwogaga J. Atake, Katie Ovens, Ruiyi Guo, Isaac Pratt, H. William Detrich, David M. L. Cooper, Thomas Desvignes, John H. Postlethwait, B. Frank Eames
Summary: The reduced bone in icefishes was not attributed to changes in bone microstructure or bone mineral density at a systemic level, but rather occured only at the gross anatomic level. Microstructural measures and bone mineral density were similar among icefish and non-icefish Antarctic notothenioids.
JOURNAL OF ANATOMY
(2022)
Article
Evolutionary Biology
Selina Patel, Clive W. Evans, Alex Stuckey, Nicholas J. Matzke, Craig D. Millar
Summary: This study reports the complete mt genomes of three trematomin notothenioids, revealing major rearrangements and gene inversions compared to the canonical mt gene order of the Antarctic silverfish. The verification of the assemblies is crucial in preventing the publication and use of erroneous data.
JOURNAL OF HEREDITY
(2022)
Article
Physiology
Milica Mandic, Amanda J. Frazier, Andrew W. Naslund, Anne E. Todgham
Summary: Notothenioid fishes, especially adult individuals, exhibit species-specific differences in cardiac metabolic capacity, which may impact their acclimation potential to changing environmental conditions.
JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMS AND ENVIRONMENTAL PHYSIOLOGY
(2022)
Article
Mathematics
Victor Mooto Nawa, Saralees Nadarajah
Summary: This paper presents closed form estimators for the beta distribution that are simpler and perform better than those proposed by Tamae, Irie, and Kubokawa. The proposed estimators have smaller asymptotic variances and covariances compared to Tamae estimators and maximum likelihood estimators. They also exhibit better performance in real data applications.
Article
Environmental Sciences
Hee-kyu Choi, Ji Eun Jang, Seo Yeon Byeon, Yu Rim Kim, Dale Maschette, Sangdeok Chung, Seok-Gwan Choi, Hyun-Woo Kim, Hyuk Je Lee
Summary: The genetic diversity of Antarctic toothfish was found to be higher in Subareas 58 than Subareas 88, suggesting larger effective population sizes in Subareas 58. Analysis of microsatellites suggested that the sampled populations likely form a single gene pool, but weak microsatellite differentiation in some population pairs hinted at the possibility of multiple genetic populations. The genetic structure of D. mawsoni appeared to be temporally stable, with no genetic differentiation observed between juveniles and adults. This study's findings will aid in developing effective stock management strategies for Antarctic toothfish, with long-term genetic monitoring recommended to understand population dynamics in response to climate changes.
FRONTIERS IN MARINE SCIENCE
(2021)
Article
Biology
Sonu Kumar, Ashutosh Singh, Asheesh Shanker
Summary: Microsatellites, also known as simple sequence repeats, are repetitive tracts in a DNA sequence that play key roles in species identification and phylogeny. The pSATdb database has been developed to provide comprehensive information on length variation of mitochondrial microsatellites across different genera. The identified microsatellites stored in pSATdb will be useful in various genomics studies.
LIFE SCIENCE ALLIANCE
(2022)
Article
Audiology & Speech-Language Pathology
James D. B. O'Sullivan, Anwen Bullen, Zoe F. Mann
Summary: Hair cells (HCs) are specialized sensory receptors in the inner ear that allow us to perceive sound and interact with the world. Mitochondria play a crucial role in HC function and death, producing ATP and regulating calcium levels. Imaging techniques have revealed distinct mitochondrial populations in different parts of the HC, and studies have shown that ototoxic agents, aging, and noise damage affect mitochondrial structure and function, leading to HC death. Understanding the relationship between mitochondrial morphology and function in normal HC function is essential for deciphering the molecular mechanisms underlying HC death.
Review
Cell Biology
T. Bradley Willingham, Peter T. Ajayi, Brian Glancy
Summary: Mitochondria exhibit heterogeneity in form and function across different cell types and even within single cells. Distinct subpopulations of mitochondria have been identified in skeletal muscle cells, but the mechanisms by which this specialization contributes to energy homeostasis in working muscles remain unclear. Advances in cellular imaging technologies have opened up new potential avenues for further investigation into mitochondrial heterogeneity.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Ecology
Wojciech Majewski, Witold Szczucinski, Andrew J. Gooday
Summary: Sub-Antarctic fjords in South Georgia were studied to understand the effect of climate change on living benthic foraminifera. Four distinct foraminiferal assemblages were identified, with Miliammina earlandi dominating in glacier-proximal habitats, Cassidulinoides aff. parkerianus in mid-fjord areas, and Globocassidulina aff. rossensis and an assemblage dominated by Ammobaculites rostratus, Reophax subfusiformis, and Astrononion echolsi in the outer fjords. Miliammina earlandi showed adaptability to glacial influence and high sedimentation rates, while C. aff. parkerianus was well-suited to inner-fjord conditions.
Article
Agricultural Engineering
Haocheng Xu, Jing Li, Hankun Wang, Xinwu Xu
Summary: The research investigates the fracture mechanism and mechanical properties of bamboo under bending-shear coupling effect. The results show bamboo's linear decrease in bending moment and constant distribution of shear force along the strip's length. The study establishes a numerical structure activity relationship, elucidating its bending-shear coupling performance and providing valuable reference for biomimetic material production.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Cell Biology
Martine Uittenbogaard, Kuntal Sen, Matthew Whitehead, Christine A. Brantner, Yue Wang, Lee-Jun Wong, Andrea Gropman, Anne Chiaramello
Summary: This study aimed to establish the mitochondrial etiology of the proband's progressive neurodegenerative disease suggestive of an atypical Leigh syndrome. Through mitochondrial bioenergetic investigations and whole exome sequencing, three heterozygous nuclear variants associated with Leigh syndrome were identified, providing insights for the development of diagnostic and therapeutic strategies for atypical Leigh syndrome.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Cell Biology
Ryan R. Cupo, Alexandrea N. Rizo, Gabriel A. Braun, Eric Tse, Edward Chuang, Kushol Gupta, Daniel R. Southworth, James Shorter
Summary: The high-resolution structure of Skd3-substrate complex is reported, revealing the mechanism of Skd3 protein disaggregation and its association with disease inheritance patterns.
Article
Cell Biology
Jonathan M. Palozzi, Swathi P. Jeedigunta, Anastasia Minenkova, Vernon L. Monteiro, Zoe S. Thompson, Toby Lieber, Thomas R. Hurd
Summary: A programmed germline mitophagy (PGM) mechanism, essential for maintaining mtDNA quality control, has been discovered through a large-scale screen.
Article
Biochemistry & Molecular Biology
Ana Mafalda Goncalves, Ana Raquel Pereira-Santos, Ana Raquel Esteves, Sandra M. Cardoso, Nuno Empadinhas
Summary: Recent studies have shown potential significance of mitochondrial ribosomal subunits in mitochondrial dysfunction in Parkinson's disease, however, the exact role of mitoribosomes remains largely unknown. Further research on the correlation between mitoribosome failure and PD pathology could lead to new clinical markers and therapeutic targets.
ANTIOXIDANTS & REDOX SIGNALING
(2021)