期刊
INSECT MOLECULAR BIOLOGY
卷 20, 期 4, 页码 529-540出版社
WILEY-BLACKWELL
DOI: 10.1111/j.1365-2583.2011.01084.x
关键词
Crithidia bombi; subtractive suppression hybridization; antimicrobial peptides; ecological immunology
资金
- BBSRC
- RCUK
- British Ecological Society
- Royal Society
Immune response dynamics in insects from natural host-parasite associations are poorly understood, despite accumulating evidence of ecological immune phenomena in these systems. Using a gene discovery approach, we have identified genes relating to signalling, enzymatic processes and respiration that were up-regulated in the bumblebee, Bombus terrestris, during infection with the trypanosomatid parasite, Crithidia bombi. In addition, we have mapped dynamic changes in the temporal expression of these genes and three candidate antimicrobial peptide (AMP) immune genes, Abaecin, Defensin and Hymenoptaecin, from 1 to 24 h after C. bombi infection. We show that dynamic changes in expression occur for individual genes at distinct phases of the immune response to C. bombi that correspond to early, intermediate and late stages of infection.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据