Article
Entomology
Mona Kordestani, Kamran Mahdian, Valiollah Baniameri, Aziz Sheikhi Garjan
Summary: This study tested the effects of three insecticides on Orius laevigatus and found that Proteus was the most toxic to female adults. Sublethal treatments prolonged the developmental duration of the immature stages in O. laevigatus and reduced its fecundity and intrinsic rate of increase. Matrine was found to be a harmless alternative to synthetic insecticides for use with O. laevigatus.
JOURNAL OF ECONOMIC ENTOMOLOGY
(2022)
Article
Environmental Sciences
Marilucia Santorum, Bertha Irina Gastelbondo-Pastrana, Elton Luiz Scudeler, Marcia Santorum, Rose Meire Costa, Daniela Carvalho Dos Santos
Summary: The use of Novaluron in Bombyx mori may have reproductive toxicity effects, affecting the morphological structure and cell development in the testes and ovaries, leading to cell death and a significant decrease in egg production.
Article
Environmental Sciences
Claire Badder, Sylvain Bart, Alex Robinson, Helen Hesketh, Peter Kille, David J. Spurgeon
Summary: In this study, a new bioassay method was developed to assess the sensitivity of lepidopteran larvae to pesticides through dietary exposure. The study demonstrated the repeatability and reliability of the method, as well as its potential to observe sub-lethal effects. The findings have important implications for chemical risk assessments and other scenarios.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Review
Agronomy
Thomas C. Sparks, Nicholas Storer, Alan Porter, Russell Slater, Ralf Nauen
Summary: IRAC, established in 1984, aims to address insecticide resistance issues in the crop protection industry. It has grown from a few agrochemical companies to a global group providing informational and educational tools for resistance management.
PEST MANAGEMENT SCIENCE
(2021)
Article
Entomology
Johnnie Van den Berg, Hannalene du Plessis
Summary: This paper reviews the history of insecticide resistance in the fall armyworm and discusses the factors that influence control efficacy and resistance evolution, such as life history traits, migration ecology, and chemical control practices. The indirect impact of national policies on pesticide use and control efficacy is also examined, highlighting the importance of integrated pest management.
JOURNAL OF ECONOMIC ENTOMOLOGY
(2022)
Article
Agriculture, Multidisciplinary
Qiong Lu, Liping Xu, Lin Liu, Yong Zhou, Tian Liu, Yongxiang Song, Jianhua Ju, Qing Yang
Summary: This study discovered the potential of lynamicin B as a natural-derived pesticide for controlling lepidopteran pests, while leaving its natural enemies unaffected. Lynamicin B showed inhibitory effects on the lepidopteran pest Ostrinia furnacalis, as well as other pests like Mythimna separata and Spodoptera frugiperda.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Yuexia Zhang, Yushi Zhang, Jiapeng Xing, Yajun Li, Yan Yang, Yubin Wang, Linjian Jiang, Mingcai Zhang, Zhaohu Li
Summary: In vitro dodder shoots actively grow for over 10 days, utilizing starch as an energy source in the basal stems and relying on glycolysis, TCA cycle, and pentose phosphate pathway for energy supply in shoot tip elongation. Efficient nutrient recycling and ROS modulation facilitate the parasitism of dodder by promoting shoot elongation growth to reach the host.
Article
Entomology
Amanda A. F. Lemes, Thamiris P. Sipriano-Nascimento, Natalia F. Vieira, Camila P. Cardoso, Alessandra M. Vacari, Sergio A. De Bortoli
Summary: The study aimed to investigate the residual and sublethal effects of indoxacarb on field and laboratory populations of diamondback moths. Results showed high toxicity of indoxacarb on the populations, with significant sublethal effects on larvae, pupae, and offspring.
JOURNAL OF ECONOMIC ENTOMOLOGY
(2021)
Article
Entomology
Marzieh Hatami, Masumeh Ziaee, Ali Asghar Seraj, Mehdi Mehrabi-Koushki, Jacek Francikowski
Summary: The study demonstrated that Imunit can reduce the survival rate and fecundity of S. cilium, making it a potential candidate for integrated pest management programs.
Review
Biochemistry & Molecular Biology
Emmanuel Pacia Hernandez, Anisuzzaman, Md Abdul Alim, Hayato Kawada, Kofi Dadzie Kwofie, Danielle Ladzekpo, Yuki Koike, Takahiro Inoue, Sana Sasaki, Fusako Mikami, Makoto Matsubayashi, Tetsuya Tanaka, Naotoshi Tsuji, Takeshi Hatta
Summary: Blood-feeding arthropods, such as ticks and mosquitoes, are important vectors of arthropod-borne diseases. Reactive oxygen species (ROS) play various roles in the interactions among pathogens, vectors, and hosts. This review examines the roles of ROS in the immunity and microbiome homeostasis of these arthropods, as well as their impact on vector potentials and insecticide resistance.
Article
Pharmacology & Pharmacy
Jin Woo Jung, Hui Li, Jung Hun Lee, Yu-Jung Hwang, Kisoon Dan, Moo Kyun Park, Dohyun Han, Myung-Whan Suh
Summary: The standard treatment for sensorineural or sudden hearing loss has been systemic oral steroid administration, but the delivery time of steroids to the inner ear is often too short for a therapeutic effect. Intratympanic steroid injections have been used as an alternative, and in this study, a dual viscosity mixture vehicle (DVV) was used for the treatment of hearing loss in guinea pigs. Proteomic analysis revealed differential expression of proteins related to inflammation, immune response, actin remodeling, and antioxidant processes. The DVV treatment resulted in the activation of cell proliferation and inhibition of apoptosis and inflammatory reactions.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Entomology
Eleanor Groden, Karla S. Boyd, Charlene Donahue
Summary: The invasive browntail moth has caused outbreaks on an unprecedented scale in the northeastern U.S. over the past five years. The health risks associated with contact with the toxic urticating hairs of the moth larvae have resulted in a low tolerance for this pest among homeowners and land managers. Few studies have been conducted to assess management options for the browntail moth, which is abundant in ecologically sensitive areas along coastal waters and around homes. This study investigated the potential of using currently available biorational insecticides to manage overwintered larvae. The results showed that Beauveria bassiana, Bacillus thuringiensis kurstaki, azadirachtin, and spinosad products were effective in reducing the abundance of larvae.
JOURNAL OF ECONOMIC ENTOMOLOGY
(2022)
Article
Medicine, General & Internal
Jingbo Yang, Chengyan He, Ning Liu
Summary: This study systematically investigated the role of curcumin as a chemosensitizer for the treatment of CRC, along with the key events responsible for its pharmaceutical effect. The results showed that curcumin enhances chemosensitivity to 5-FU through several mechanisms.
FRONTIERS IN MEDICINE
(2022)
Article
Entomology
Lisa J. Bird, Paul W. Walker, Linda J. Drynan
Summary: This study monitored the annual indoxacarb resistance in Helicoverpa armigera populations collected from various crops in Australia. The resistance frequency was lowest in the 2013-2014 and 2015-2016 seasons, then increased significantly to a ten-year high in 2018-2019 but declined during a severe drought in 2019-2020. Two indoxacarb resistant strains were identified, with one strain showing reduced sensitivity to chlorantraniliprole.
JOURNAL OF ECONOMIC ENTOMOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Mao-Ye Li, Xiao-Hui Tu, Ye Cao, Shi-Guang Li, Su Liu
Summary: Insecticide exposure can lead to oxidative stress in insects, with the analysis in this study showing that PrSOD1 plays a crucial role in protecting P. rapae against oxidative damage and potential tolerance to chlorantraniliprole.
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
(2021)
Article
Mathematical & Computational Biology
Kirsty L. Hey, Hiroshi Momiji, Karen Featherstone, Julian R. E. Davis, Michael R. H. White, David A. Rand, Baerbel Finkenstaedt
Article
Cell Biology
J. Bagnall, C. Boddington, J. Boyd, R. Brignall, W. Rowe, N. A. Jones, L. Schmidt, D. G. Spiller, M. R. H. White, P. Paszek
INTEGRATIVE BIOLOGY
(2015)
Article
Biochemistry & Molecular Biology
Nicola J. Smyllie, Violetta Pilorz, James Boyd, Qing-Jun Meng, Ben Saer, Johanna E. Chesham, Elizabeth S. Maywood, Toke P. Krogager, David G. Spiller, Raymond Boot-Handford, Michael R. H. White, Michael H. Hastings, Andrew S. I. Loudon
Article
Endocrinology & Metabolism
Anne V. McNamara, Antony D. Adamson, Lee S. S. Dunham, Sabrina Semprini, David G. Spiller, Alan S. McNeilly, John J. Mullins, Julian R. E. Davis, Michael R. H. White
MOLECULAR ENDOCRINOLOGY
(2016)
Article
Multidisciplinary Sciences
Antony Adamson, Christopher Boddington, Polly Downton, William Rowe, James Bagnall, Connie Lam, Apolinar Maya-Mendoza, Lorraine Schmidt, Claire V. Harper, David G. Spiller, David A. Rand, Dean A. Jackson, Michael R. H. White, Pawel Paszek
NATURE COMMUNICATIONS
(2016)
Article
Biology
Nick E. Phillips, Cerys S. Manning, Tom Pettini, Veronica Biga, Elli Marinopoulou, Peter Stanley, James Boyd, James Bagnall, Pawel Paszek, David G. Spiller, Michael R. H. White, Marc Goodfellow, Tobias Galla, Magnus Rattray, Nancy Papalopulu
Article
Biology
Karen Featherstone, Kirsty Hey, Hiroshi Momiji, Anne V. McNamara, Amanda L. Patist, Joanna Woodburn, David G. Spiller, Helen C. Christian, Alan S. McNeilly, John J. Mullins, Baerbel F. Finkenstaedt, David A. Rand, Michael R. H. White, Julian R. E. Davis
Article
Biology
John M. Ankers, Raheela Awais, Nicholas A. Jones, James Boyd, Sheila Ryan, Antony D. Adamson, Claire V. Harper, Lloyd Bridge, David G. Spiller, Dean A. Jackson, Pawel Paszek, Violaine See, Michael R. H. White
Article
Cell Biology
Katie Lloyd, Stamatia Papoutsopoulou, Emily Smith, Philip Stegmaier, Francois Bergey, Lorna Morris, Madeleine Kittner, Hazel England, Dave Spiller, Mike H. R. White, Carrie A. Duckworth, Barry J. Campbell, Vladimir Poroikov, Vitor A. P. Martins dos Santos, Alexander Kel, Werner Muller, D. Mark Pritchard, Chris Probert, Michael D. Burkitt
DISEASE MODELS & MECHANISMS
(2020)
Article
Cell Biology
Daniel Friedman, Poppy Simmonds, Alexander Hale, Leoma Bere, Nigel W. Hodson, Michael R. H. White, Daniel M. Davis
Summary: NK cells are more effectively stimulated to secrete various antibodies when encountering stiff targets compared to soft targets, which may impact NK cell recognition and response. Varying target stiffness can alter the mechanosensitivity of immune synapses, highlighting soft targets as a blind spot in NK cell recognition.
JOURNAL OF CELL SCIENCE
(2021)
Article
Multidisciplinary Sciences
Polly Downton, Fabio Sanna, Robert Maidstone, Toryn M. Poolman, Edward A. Hayter, Suzanna H. Dickson, Nick A. Ciccone, James O. Early, Antony Adamson, David G. Spiller, Devin A. Simpkins, Matthew Baxter, Roman Fischer, Magnus Rattray, Andrew S. I. Loudon, Julie E. Gibbs, David A. Bechtold, David W. Ray
Summary: Chronic inflammation is associated with metabolic dysfunction, with a temporal crosstalk between inflammatory and metabolic processes. Research has shown that arthritis drives changes in lipid metabolism and mitochondrial function, leading to the accumulation of bioactive lipid species.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Biology
Alex A. Koch, James S. Bagnall, Nicola J. Smyllie, Nicola Begley, Antony D. Adamson, Jennifer L. Fribourgh, David G. Spiller, Qing-Jun Meng, Carrie L. Partch, Korbinian Strimmer, Thomas A. House, Michael H. Hastings, Andrew S. Loudon
Summary: This study develops a quantitative model to explain how a finite pool of BMAL1 protein regulates gene expression at thousands of target sites over daily time scales. By tracking dynamic changes in endogenous labeled proteins in tissues, the researchers determine the contribution of multiple rhythmic processes in coordinating BMAL1 DNA binding. The results also reveal the role of nuclear BMAL1 concentration in determining CLOCK and the mechanism of repression of CLOCK:BMAL1 through interactions with PER2:CRY1 and BMAL1:CRY1.
Article
Cell Biology
Samantha J. McDonnell, David G. Spiller, Michael R. H. White, Ian A. Prior, Luminita Paraoan
CELL DEATH DISCOVERY
(2019)