Article
Chemistry, Inorganic & Nuclear
Jin Wang, Zhi-Meng Zhang, Ming-Xue Li
Summary: The synthesis of four metal complexes and their antimicrobial and cytotoxic activities were investigated in this study. The results showed that the antibacterial activity of cadmium (II) and antimony (III) complexes was enhanced compared to their ligands, with Cd2 and Sb2 demonstrating effective antibacterial activity and Cd2 showing the most effective antiproliferative activity against HepG2 cells.
INORGANICA CHIMICA ACTA
(2022)
Article
Biochemistry & Molecular Biology
Adriana Corina Hangan, Roxana Liana Lucaciu, Alexandru Turza, Lucia Dican, Bogdan Sevastre, Emoeke Pall, Luminita Simona Oprean, Gheorghe Borodi
Summary: The discovery of new non-toxic metal complexes with biological activity is an active area of research. Two Cu+2 complexes with new ligands were synthesized and characterized by X-ray crystallography. Both complexes showed in vitro biological activities, with complex C2 being more active. The complexes exhibited distorted square pyramidal square-planar geometries and were characterized by FT-IR and UV-Vis spectroscopy. The antibacterial activity of the complexes against four Gram-positive and two Gram-negative bacteria was determined using the microdilution method, and cytotoxicity studies were carried out on tumor cell lines and a normal cell line. Flow cytometric assessment of apoptosis induced by the complexes was also performed.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Inorganic & Nuclear
Cristina Gonzalez-Garcia, Cristina Garcia-Pascual, Rodrigo Buron, David G. Calatayud, Josefina Perles, M. Antonia Mendiola, Elena Lopez-Torres
Summary: In this study, a new dissymmetric bis(thiosemicarbazone) ligand was prepared and characterized. The reactivity of this ligand and the hybrid isopropylthiosemicarbazone/naphtoylhydrazone with zinc(II), copper(II), and nickel(II) nitrates was explored. The results showed that the deprotonation of the ligand could not be selectively controlled. Additionally, different supramolecular architectures were formed based on the degree of deprotonation of the ligands and the presence of nitrate ions.
Article
Chemistry, Inorganic & Nuclear
Jin Wang, Yu-Ting Wang, Jiang-Nan Chang, Ming-Xue Li
Summary: The article describes the synthesis and characterization of two nickel complexes of 2-acetylpyrazine thiosemicarbazone, and studies their antibacterial activities. It was found that one of the complexes showed effective antimicrobial activity against tested bacteria, and that complex 2 exhibited inhibitory activity against human hepatocellular carcinoma HepG2 cells. Additionally, toxicity study showed that complex 2 had the highest tumor cell selectivity.
INORGANIC CHEMISTRY COMMUNICATIONS
(2021)
Article
Chemistry, Physical
Swarup Kumar Tarai, Arup Tarai, Saikat Mandal, Bhaskar Nath, Ipsita Som, Rituparna Bhaduri, Arka Bagchi, Solanki Sarkar, Arunima Biswas, Sankar Ch. Moi
Summary: The bidentate ligand thiosemicarbazone (H3L) and its Ni(II) complex were synthesized and characterized. The complexes have square planar geometry and show binding abilities with DNA and BSA. The DFT/TD-DFT simulations and theoretical analysis provided insights into the reactivity, bonding mode, and bio-molecular affinity of the compounds. The compounds also demonstrated antiproliferative activity and cell death mechanisms against HEK293 and MCF-7 cell lines.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Physical
Jisha George, V. S. Lekha, Rathika G. Nath, Y. Sheena Mary, Jamelah S. Al-Otaibi, K. Rajesh
Summary: The crystal structure and theoretical optimization of 4-tertiarybutylcyclohexanonethiosemicarbazone were investigated, and molecular docking and in vitro cell assays revealed its potential as an antitumor agent.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Chemistry, Inorganic & Nuclear
E. S. Cakmakci, E. Subasi, E. Ozturk, A. Sahiner, B. Sen Yuksel
Summary: Metal(II) complexes including Co(II), Ni(II), Pd(II) and Zn(II) were synthesized and characterized. These complexes were obtained by reacting metal(II) chlorides with the ligand. The structures and properties of these complexes were determined by various characterization techniques including elemental analysis, FT-IR, 1H NMR, and single crystal X-ray diffraction.
INORGANICA CHIMICA ACTA
(2023)
Article
Biochemistry & Molecular Biology
Aaron Teran, Giarita Ferraro, Paola Imbimbo, Ana E. Sanchez-pelaez, Daria Maria Monti, Santiago Herrero, Antonello Merlino
Summary: This study explores the interaction between paddlewheel diruthenium complexes and proteins, and finds that their selectivity towards proteins is determined by their charge and steric properties. The anticancer activity of diruthenium derivatives is correlated with the number of ligands, steric hindrance, and core electronic density.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Inorganic & Nuclear
Safa Faris Kayed, Yang Farina, Jim Simpson, Ibrahim Baba
Summary: Zn(II), Cd(II) and Ni(II) complexes of 2-acetylbenzothiophene-3-thiosemicarbazone and 2-acetylbenzothio-phene-4-ethyl-3-thiosemicarbazone have been synthesized and characterized. The electronic structures of the ligands and complexes were studied using density functional theory. The Cd complexes showed strong inhibitory actions against certain bacteria, while the Ni complex showed strong activity against Staphylococcus aureus.
INORGANIC CHEMISTRY COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Yulia P. Tupolova, Leonid D. Popov, Valery G. Vlasenko, Konstantin B. Gishko, Anna A. Kapustina, Alexandra G. Berejnaya, Yuliya A. Golubeva, Lyubov S. Klyushova, Elizaveta V. Lider, Vladimir A. Lazarenko, Stanislav S. Bachurin, Igor N. Shcherbakov
Summary: Based on the bis-hetarylhydrazone H2L, a series of mononuclear copper(ii) coordination compounds were synthesized and their structures were studied using several methods. The copper center in these compounds is in a square pyramidal environment. The cytotoxic activity of the compounds against HepG2 and MRC-5 cell lines was evaluated, and the Cu(ii) complexes showed significant dose-dependent cytotoxic effects.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Organic
Eman A. E. El-Helw, Mahmoud Asran, Mohammad E. Azab, Maher H. Helal, Sayed K. Ramadan
Summary: A series of heterocycles based on benzoquinoline were synthesized and their antitumor and antioxidant activities were screened. The results revealed that triazole thione and thiazole derivatives exhibited the most potent activity.
POLYCYCLIC AROMATIC COMPOUNDS
(2023)
Article
Chemistry, Physical
Yassine Laamari, Mourad Fawzi, Mouhi Eddine Hachim, Abdoullah Bimoussa, Ali Oubella, El Mostafa Ketatni, Mohamed Saadi, Lahcen El Ammari, My Youssef Ait Itto, Hamid Morjani, Mostafa Khouili, Aziz Auhmani
Summary: In this paper, a novel method for synthesizing thymol derivatives was reported, and the structures of all compounds were identified using spectroscopic techniques. The selectivity of the reactions was determined through theoretical calculations and experimental verification. The electronic interaction properties of the synthesized compounds were analyzed. Additionally, the cytotoxic effects of the compounds were evaluated, and compounds 6b and 6c showed promising anticancer activity against A-549 cell lines.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Biochemistry & Molecular Biology
Priyanka Khanvilkar, Soumya R. Dash, Alisagar Vohra, Ranjitsinh Devkar, Debjani Chakraborty
Summary: New ferrocenyl substituted thiosemicarbazone ligands and their binuclear ruthenium(II) arene complexes have been synthesized and characterized. The structures were established through DFT calculations, and the interactions of the complexes with DNA and BSA have been studied, showing intercalation binding with DNA and good binding affinity with BSA. In vitro cytotoxicity assays against HeLa cell line demonstrated higher potency and cytotoxicity of the complexes at low concentrations.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2021)
Article
Biochemistry & Molecular Biology
Carolane M. Almeida, erica C. M. Nascimento, Joao B. L. Martins, Tales H. A. da Mota, Diego M. de Oliveira, Claudia C. Gatto
Summary: The current research focuses on the synthesis, characterization, and biological activity evaluation of two metal complexes, [Au(L)Cl][AuCl2] (1) and [Pd(L)Cl]& BULL;DMF (2), with a 2-acetylpyridine N(4)-cyclohexyl-thiosemicarbazone ligand. The molecular structures of the complexes were determined using various methods, including single crystal X-ray diffraction. The complexes exhibited a square planar geometry and showed promising antitumor activity against human glioma U251 cells, particularly complex (1) compared to complex (2) and the free ligand. Molecular docking simulations were also performed to predict the interactions of the synthesized compounds with selected proteins and DNA.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Applied
Carolane M. Almeida, Pedro H. S. Marcon, Erica C. M. Nascimento, Joao B. L. Martins, Marcio A. S. Chagas, Mahmi Fujimori, Patricia G. F. De Marchi, Eduardo L. Franca, Adenilda C. Honorio-Franca, Claudia C. Gatto
Summary: This study documented the synthesis and characterization of two new organometallic Au (III) and Pt (II) complexes with 2-acetylthiophene-N(3)-methylthiosemicarbazone (HL). The compounds were characterized using various spectroscopic techniques including X-ray diffraction and MS. The results revealed the coordination of the thiosemicarbazone ligand to the Au (III) and Pt (II) metal atoms in a tridentate mode. The compounds exhibited interactions in their molecular packing, as demonstrated by quantitative analysis of the 3D Hirshfeld surface and 2D fingerprint results. The biological activity of the compounds against MCF-7 human cancer cells was evaluated, and their inhibitory activity was predicted using molecular docking.
APPLIED ORGANOMETALLIC CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Anjum Afrooze, Dadamiah P. M. D. Shaik
Summary: This study presents a solution combustion approach to produce marigold Co3O4 nanoparticles as potential electrode material for supercapacitors. The effect of vacuum annealing on the microstructural and electrochemical properties is explored, and the prepared nanoparticles exhibit high specific capacitance and electrochemical stability.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
A. Atta, Nuha Al-Harbi, B. M. Alotaibi, M. A. M. Uosif, E. Abdeltwab
Summary: In this study, PVA/NaI films were prepared by doping polyvinyl alcohol with sodium iodide. The films were then irradiated with argon ions at different fluence levels. Various characterization techniques were used to study the structural and electrical changes in the films. The results show that the dielectric behavior of the treated PVA/NaI films was significantly modified, making them more suitable for various devices.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Xingang Wang, Chao Ma, Fubing Zou, Hai Hu, Jiayu Li, Hongyun Luo
Summary: By hybridizing TiO2 photocatalyst with CaCO3 as the wall material and using linseed oil as the core material, self-cleaning and self-repairing microcapsules were produced using in-situ precipitation. The microcapsules were evaluated for their morphology, chemical composition, thermal stability, and self-cleaning and self-repairing properties. Results showed that the microcapsules had a rough and spherical surface, along with excellent thermal stability and repeatability. Increasing the dosage of microcapsules significantly increased the degradation rate of methylene blue, while the self-repairing effect of micro-cracks became more evident. The optimal microcapsule dosage was found to be 7.0 wt%.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)
Review
Chemistry, Inorganic & Nuclear
Muhammad Farooque Lanjwani, Mustafa Tuzen, Muhammad Yar Khuhawar, Tawfik A. Saleh
Summary: The development of the textile industry has raised concerns due to the contamination of drinking water by organic dyes, which pose a carcinogenic risk to humans. Nanomaterials, particularly semiconductors, have been utilized for photocatalytic degradation of dye pollutants. Various parameters, such as catalyst dosage, irradiation time, light sources, initial dye concentration, temperature, and pH, play significant roles in the degradation process. Different generations of photocatalytic nanomaterials, including single metal nanoparticles, binary and ternary metal oxides, as well as inert solid substrates with photocatalysts, have been employed for dye degradation.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
V. Ramasamy, E. Thenpandiyan, G. Suresh, T. Sathishpriya, Suresh Sagadevan
Summary: The nano CaCO3 and Eu3+ doped CaCO3/PEG nanocomposites were prepared through the biomimetic method. The prepared products were characterized and the electrochemical performance was evaluated. The results showed that the Eu3+ doped CaCO3/PEG nanocomposite exhibited superior pseudocapacitive behavior and could be used as an electrode material for supercapacitor applications.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Shuxiang Duan, Ping Li, Hongqiang Zhang, Suping Qu
Summary: Panax ginseng, as an ethnomedicinal plant, has therapeutic effects in traditional medicine. This study investigated the potential use of green-synthesized silver nanoparticles from Panax ginseng leaf extract for the treatment of lung carcinoma and heart protection against mitochondrial dysfunction and cardiac dysfunction in obese insulin-resistant rats. The silver nanoparticles showed spherical morphology with a size range of 12.11 to 43.33 nm. In vivo experiments demonstrated that the silver nanoparticles significantly improved metabolic parameters, heart rate variability, cardiac function, and cardiac mitochondrial function in the rats. This study suggests that silver nanoparticles derived from Panax ginseng have cardioprotective effects.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Maryam Fayazi, Elham Rezvannejad
Summary: In this study, propolis extract was used as a green reductant to deposit silver nanoparticles on sepiolite clay, creating a nanocomposite called Sep/Ag. The nanocomposite was characterized using various techniques, and its ability to adsorb methylene blue (MB) was examined. The results showed that Sep/Ag could efficiently remove MB from solution, and the adsorbent could be regenerated for multiple cycles. This research demonstrates the potential of Sep/Ag nanocomposite as an effective and environmentally friendly sorbent for environmental cleanup.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
M. Sriramraj, A. R. Balu, S. Chitra Devi, B. Sowmiya Devi, M. Suganya, K. Devendran, M. Karthika, S. Adityan
Summary: One-pot green synthesis was used to prepare rGO decorated MgTiO3 perovskite using Solanum trilobatum leaf extract to reduce graphene oxide. The rGO embedded MgTiO3 nanoparticles showed smaller crystallite size, well-defined particle boundaries, increased photodegradation efficiency and antibacterial activity compared to pure MgTiO3.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Zhiliang Guo, Qianheng He, Helin Wang, Changgan Lai, Shuai Ji, Jian Sun, Donghuai Zhang, Liu Nie, Lixu Lei
Summary: Waste plastics are causing serious environmental pollution and there is a pressing need for their recycling. This study presents a novel method to completely degrade waste PET into sodium terephthalate and ethylene glycol through a solid-state reaction at high temperature with minimal solvent. The method offers high efficiency, selectivity, and ease of product separation, making it a promising approach for the recycling economy of other ester-based waste polymers.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Hanan Alhussain, Nuha Y. Elamin, Laila S. Alqarni, Abuzar Albadri, Kamal K. Taha, A. Modwi
Summary: A CaO-TiO2@g-C3N4 sorbent was constructed using sonication method for the elimination of RhB dye from aqueous medium. The sorbent demonstrated equilibrium for the dye adhesion after 120 minutes, with a maximum adsorption capacity of 778.7 mg/g. The nanocomposite showed satisfactory performance in neutral aquatic conditions.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Wei-Dong Liu, Liu-Qing Chen, Qi-Hao Qiu, Ming-Qiang Qi, Han Xu, Chao-Long Chen, La-Sheng Long, Lan-Sun Zheng, Xiang-Jian Kong
Summary: In this study, a mixed valence cerium-oxo cluster was successfully synthesized through low-temperature crystallization, and the coexistence and distribution of Ce ions in different valence states were determined. The mechanism for the generation of +4 valence state was revealed, and the synthesized cluster exhibited strong ultraviolet absorption and long visible light absorption, as well as clear photocurrent response and high photocurrent intensity.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Mahak Dalal, Nidhi Antil, Binesh Kumar, Jai Devi, Sapana Garg
Summary: This research study focuses on the biological efficacy of a newly synthesized Schiff base ligand and its aryltellurium(IV) complexes. The synthesized compounds were characterized using various physical and spectral investigations, and theoretical chemical estimations were also conducted. The results showed that the complexes exhibited mild to strong antimicrobial activity, with higher activity than the Schiff base. Molecular docking experiments revealed the ability of the compounds to bind to receptors. ADMET results indicated favorable drug-like behavior of the synthesized compounds. Overall, these complexes may serve as promising candidates for infection ailments.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Indu Sharma, Ajay Kumar, Jaspreet Kaur, Sanjay Mehra, Arvind Kumar, Suresh Kumar Sharma, Surinder Kumar Mehta, Ramesh Kataria
Summary: Nanozyme based sensors have been developed as an effective method for detecting harmful metal ions in water samples. In this study, a Co(II) based coordination polymer nanoparticle (Co-CP NP) was synthesized and utilized as a nanozyme to detect Fe(II) ions selectively. The Co-CP NP exhibited peroxido-reductase mimicking activity, and the detection limit for Fe(II) ions was found to be 0.66 μM. The catalytic action of the Co-CP NP was further analyzed using Michaelis-Menten kinetics, and the detection mechanism was elucidated through XPS and zeta potential analysis.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Sreenivasulu Venkata Kummari, Vadali Venkata Satya Siva Srikanth
Summary: A simple single-step sonochemical reduction method is used to prepare CoFe2O4-CoFe-reduced graphene oxide (rGO) composites with control of rGO content. The tunable interfacial magnetic proximity-induced magnetization at the interface of CoFe2O4-CoFe and rGO is observed.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Asma Zaka, Muhammad Waqas Iqbal, Amir Muhammad Afzal, Hassabul Hassan, Sarah Alharthi, Mohammed A. Amin, Ahmad M. Saeedi, Hasan B. Albargi, A. Alhadrami, Nawal D. Alqarni, Mohd Zahid Ansari
Summary: The tailoring and rational synthesis of metal-organic framework (MOF) with versatile nano/microarchitectures are of great academic interest due to their promising applications in advanced energy storage devices. A simple and cost-effective hydrothermal method was used to synthesize the carbon nanotubes (CNT) doped Cu-MOF, exhibiting astonishing power and energy density.
INORGANIC CHEMISTRY COMMUNICATIONS
(2024)