期刊
INORGANIC CHEMISTRY COMMUNICATIONS
卷 13, 期 4, 页码 537-539出版社
ELSEVIER
DOI: 10.1016/j.inoche.2010.01.031
关键词
Fluorinated porphyrin; DNA cleavage; Photodynamic therapy; Ruthenium
资金
- Merck Institute for Science Foundation
Two ruthenium substituted porphyrins differing only by the substitution of a mesopentafluorophenyl group show drastically different DNA photocleavage results. The incorporation of the pentafluorophenyl group provides greater photodynamic efficiency and in addition is capable of causing DNA cleavage in the absence of oxygen. (c) 2010 Elsevier B.V. All rights reserved.
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