Article
Chemistry, Multidisciplinary
Hamid R. Shahsavari, Samira Chamyani, Reza Babadi Aghakhanpour, Vahideh Dolatyari, Sareh Paziresh
Summary: Two categories of cycloplatinated(ii) complexes were synthesized and their photophysical properties were investigated. The absorption and emission spectra of these complexes showed distinct differences under different conditions.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Sergej Stipurin, Thomas Strassner
Summary: A total of six novel platinum complexes were successfully synthesized from saturated N-heterocyclic carbene precursors, showing strong emissive properties in the sky-blue region of the visible spectrum with quantum yields up to 71% in a PMMA matrix. The structures were characterized by NMR experiments and solid-state analyses, confirming the cyclometalation and saturated backbone of the NHC motif. DFT calculations were used to examine the photophysical and electrochemical properties of the platinum complexes.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2021)
Article
Chemistry, Inorganic & Nuclear
Andrea Corral-Zorzano, David Gomez de Segura, Elena Lalinde, M. Teresa Moreno
Summary: We have investigated a range of dicationic heteroleptic complexes with two cyclometalating 2-phenylbenzothiazole (pbt) groups and a phenanthroline-based ligand. The photophysical and electrochemical properties of these complexes were studied, and different emissive states were observed depending on the medium and excitation wavelength. Theoretical calculations supported these findings and provided insights into the luminescence of these PtIV complexes.
DALTON TRANSACTIONS
(2023)
Article
Chemistry, Inorganic & Nuclear
Sergej Stipurin, Thomas Strassner
Summary: The synthesis of N-heterocyclic carbene precursors and their cyclometalated platinum(II) carbene complexes based on hexahydroimidazo[1,5-a]pyridine are reported in this study. The properties of these platinum complexes were characterized by various techniques, and their photophysical and electrochemical behaviors were investigated. Quantum chemical calculations were used to rationalize the experimental results.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2022)
Article
Chemistry, Medicinal
Jing Yang, Lei Chen, Peng-Chao Wang, Bo Yang, Chuan-Zhu Gao
Summary: This study developed a series of cyclometalated platinum (II) complexes with near-infrared phosphorescent emission targeting carbonic anhydrase IX (CAIX). These complexes showed high binding affinity and effective inhibition on CAIX in vitro. The complexes demonstrated significantly enhanced therapeutic effect on multiple cancer cell lines compared to cisplatin and had higher selectivity towards cancer cells.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Angela Vivancos, Delia Bautista, Pablo Gonzalez-Herrero
Summary: This study reports the synthesis, structure, photophysical properties, and electrochemistry of the first series of Pt(IV) tris-chelates bearing cyclometalated aryl-NHC ligands. The complexes exhibit significant photostability, long-lived phosphorescence, and potential application for Pt(IV) emitters with tunable properties.
INORGANIC CHEMISTRY
(2022)
Article
Materials Science, Multidisciplinary
Bo-Sun Yun, So-Yoen Kim, Jin-Hyoung Kim, Ho-Jin Son, Sang Ook Kang
Summary: In this study, NHC-Ir complexes utilizing DBT and DBF moieties to enhance deep-blue phosphorescence emission efficiency were synthesized and compared for their electrochemical and photophysical properties. The use of DBT moieties resulted in longer emission wavelengths, while the meridional isomer exhibited easier oxidation and red-shifted emission compared to facial forms. The replacement of the oxygen atom in the DBF unit with sulfur did not significantly alter the emission efficiency, achieving high-end deep-blue phosphorescence with unprecedented CIE coordinates.
JOURNAL OF MATERIALS CHEMISTRY C
(2021)
Article
Chemistry, Multidisciplinary
Vasily Sivchik, Aleksandr Kochetov, Toni Eskelinen, Kristina S. Kisel, Anastasia Solomatina, Elena Grachova, Sergey P. Tunik, Pipsa Hirva, Igor O. Koshevoy
Summary: The luminescent cyclometalated complexes decorated with cyanide ligand can serve as nucleophilic building blocks for halogen-bonded adducts, with noncovalent interactions playing a key role in their photoluminescent properties and excited states. The degree of aggregation via metal-metal interactions determines the optoelectronic properties and photoemissive characteristics of the crystalline materials.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Chemistry, Inorganic & Nuclear
Piermaria Pinter, Johannes Soellner, Thomas Strassner
Summary: Platinum(II) complexes exhibit unique photophysical behavior due to their square-planar geometry. The photophysical properties of monometallic platinum(II) complexes are dependent on concentration, while those of bimetallic complexes are dependent on the distance between metal centers. This study reveals a correlation between the electronic and photophysical properties of monomeric monometallic platinum(II) complexes and their aggregates with corresponding bimetallic complexes.
Article
Chemistry, Inorganic & Nuclear
Violeta Sicilia, Lorenzo Arnal, Daniel Escudero, Sara Fuertes, Antonio Martin
Summary: DFT investigations were carried out on platinum-butterfly complexes with different conformations, revealing that spread conformers are more stable. In solid state, different conformations emit light of different colors, with mechanical grinding resulting in enhanced luminescence quantum yield.
INORGANIC CHEMISTRY
(2021)
Article
Chemistry, Inorganic & Nuclear
Sergej Stipurin, Thomas Strassner
Summary: Three different imidazolylidene ligand precursors with methyl groups in 4- and 5-position were synthesized to build a series of nine cyclometalated platinum(II) complexes, using β-diketonate and bis(pyrazolyl)borate motifs as auxiliary ligands. The synthesized platinum complexes exhibit room temperature phosphorescence in a PMMA matrix with high quantum yields and specific color coordinates. Additional insight into the properties of these compounds was gained through quantum chemical calculations and electrochemical experiments.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Baoning Li, Yongguang Li, Michael Ho-Yeung Chan, Vivian Wing-Wah Yam
Summary: This study reported a series of cyclometalated platinum(II) complexes with unique photophysical properties, investigating their luminescent, chiroptical, and self-assembly behaviors. An isodesmic growth mechanism was found for their self-assembly process, and the chiral sense of the enantiomers could be transferred and amplified via intermolecular noncovalent interactions. Distinctive phosphorescent properties and nanostructured morphologies were observed for enantiomers 4R and 4S, supported by various analytical techniques.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Applied
Irene Melendo, Javier Camacho-Aguayo, Sareh Paziresh, Sara Fuertes, Antonio Martin, Susana de Marcos, Javier Galban, Violeta Sicilia
Summary: New beta-diketonate platinum (II) complexes with bright phosphorescent emission and high quantum yield were synthesized and characterized. One of these complexes was used as a dye for sensing glucose levels.
Article
Chemistry, Medicinal
Wenting Wang, Pengchao Wang, Xiali Liao, Bo Yang, Chuanzhu Gao, Jing Yang
Summary: In this study, four planar cyclometalated platinum(II) complexes with enlarged aromatic rings were evaluated as effective anticancer theranostic agents for the first time. The increased number of aromatic rings in the N?N ligand led to increased lipophilicity and cytotoxicity selectivity. The interaction between the complexes and biomolecules was indicated by enhanced NIR and green emissions, with different distributions and induction of cell death efficiency.
JOURNAL OF MEDICINAL CHEMISTRY
(2023)
Article
Chemistry, Applied
Isami Nakajima, Minori Shimizu, Yuta Okuda, Ryo Akiyama, Ryu Tadano, Masahiro Nagaoka, Naohiro Uemura, Yasushi Yoshida, Takashi Mino, Hiraku Shinozaki, Tetsuya Yamamoto
Summary: In this study, a specific complex was synthesized and used as a catalyst to achieve the 1,2-addition reactions of organoboron compounds under base-free conditions.
ADVANCED SYNTHESIS & CATALYSIS
(2022)
Article
Chemistry, Multidisciplinary
Riccardo Bonsignore, Sophie R. Thomas, Mathilde Rigoulet, Christian Jandl, Alexander Poethig, Didier Bourissou, Giampaolo Barone, Angela Casini
Summary: The reactivity of gold complexes extends beyond pi-activation, showing promises for selective cross-couplings in various bond forming reactions. A gold-mediated C(sp(2))-C(sp) bond forming reaction was reported, and key intermediates were characterized using NMR, HR-ESI-MS, and crystallographic studies. DFT calculations provided insight into the structure and energetics, demonstrating rare examples of C(sp(2))-C(sp(2)) cross-couplings at Au(III).
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Chemistry, Inorganic & Nuclear
Riccardo De Marco, Marco Dal Grande, Marco Baron, Laura Orian, Claudia Graiff, Thierry Achard, Stephane Bellemin-Laponnaz, Alexander Pothig, Cristina Tubaro
Summary: A series of gold complexes with N-heterocyclic carbene ligands functionalized with a pendant thioether group were synthesized and characterized, showing moderate in vitro cytotoxicity towards breast cancer cells MCF7. The experimental aspects were rationalized through relativistic DFT calculations.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Shengyang Guan, David C. Mayer, Christian Jandl, Sebastian J. Weishaeupl, Angela Casini, Alexander Poethig
Summary: A new solvatomorph of [Au-3(1-Methylimidazolate)(3)] has been identified and structurally characterized, showing dimer formation in the solid state driven by aurophilic interactions. Photophysical study combined with PXRD analysis revealed that all powder samples accessed from different preparation methods exhibit the same crystal structure. Strong thermochromism of the solid-state material was observed, ruling out a significant phase transition for the drastic change in emission properties.
Article
Chemistry, Inorganic & Nuclear
Thomas Pickl, Alexander Poethig
Summary: The study presents the synthesis, structural characterization, and photophysical properties of two new dinuclear PdII and Pt-II-NHC complexes. The d(8) metal ions are coordinated in a slightly distorted square-planar arrangement, exhibiting unique structural features and photoluminescence properties in both the solid state and in solution.
Article
Chemistry, Multidisciplinary
Sebastian Koller, Philippe Klein, Katja Reinhardt, Lukas Ochmann, Antonia Seitz, Christian Jandl, Alexander Poethig, Lukas Hintermann
Summary: A group of transition-metal catalyzed hydrogen moving reactions have been studied, with synthetic access routes established for a toolbox of structurally varied ligands and pincer complexes. Asymmetrically modified versions of established catalysts have been prepared for research towards asymmetric catalytic hydrogen moving reactions, showing potential in various model reactions such as transfer hydrogenation and alkene isomerization.
HELVETICA CHIMICA ACTA
(2021)
Article
Chemistry, Inorganic & Nuclear
Katja Reinhardt, Sebastian Koller, Philippe Klein, Corvin Lossin, Julia Gatzka, Philipp J. Altmann, Alexander Poethig, Lukas Hintermann
Summary: The study focuses on the attachment of di(1R)-menthylphosphino fragments to molecular scaffolds to create homochiral, bulky phosphine ligands for potential applications in coordination chemistry and transition-metal catalysis. Various transformations and reactions involving dimenthylphosphine P-oxide are explored, leading to the synthesis of new ligands and complexes with specific reactivity profiles due to the presence of menthyl groups. This approach shows promise for use in model palladium-catalyzed coupling reactions, with ligand 22 exhibiting high enantioselectivity in a specific biaryl-forming reaction.
Article
Chemistry, Physical
Sebastian J. Weishaeupl, Yang Cui, Simon N. Deger, Hamad Syed, Aleksandr Ovsianikov, Juergen Hauer, Alexander Poethig, Roland A. Fischer
Summary: Multiphoton absorption (MPA) is of great interest in modern materials research, and metal-organic frameworks and coordination polymers (CPs) are potential materials to overcome the limitations of commonly used chromophore molecules. This article reports the synthesis and characterization of three new highly MPA-active CPs, and demonstrates their large two-photon absorption cross-sections, which are among the highest reported for CPs to date.
CHEMISTRY OF MATERIALS
(2022)
Article
Chemistry, Inorganic & Nuclear
Joao Guilherme M. de Carvalho, Korbinian Geisser, Sebastian J. Weishaeupl, Roland A. Fischer, Alexander Poethig
Summary: A tetratopic bis(diphenylamino)anthraquinone linker is presented in this study. Its physicochemical and emissive properties are evaluated, and it successfully coordinates alkaline earth metals to form four new reported metal-organic frameworks (MOFs). The catalytic behavior of the ligand and the MOF materials towards the photooxidation of sulfides is also described.
INORGANIC CHEMISTRY
(2022)
Article
Chemistry, Medicinal
Valeria Scalcon, Riccardo Bonsignore, Jana Aupic, Sophie R. Thomas, Alessandra Folda, Alexandra A. Heidecker, Alexander Pothig, Alessandra Magistrato, Angela Casini, Maria Pia Rigobello
Summary: Two new hybrid metallodrugs of Au(III)(AuTAML)and Cu(II) (CuTAML) were designed to synergize the anticancer activity of both the metal centerand the organic ligand. These drugs showed antiproliferative effects against breast cancer cells and retained binding activity to estrogen receptor (ERα). Furthermore, they exhibited different reactivities and cytotoxic potencies, but displayed a capacity to induce mitochondrial damage.
JOURNAL OF MEDICINAL CHEMISTRY
(2023)
Article
Chemistry, Physical
Denise Lovison, Tobias Berghausen, Sophie R. Thomas, Jonathan Robson, Markus Drees, Christian Jandl, Alexander Poethig, Patrick Mollik, Dominik P. Halter, Walter Baratta, Angela Casini
Summary: In this study, water-soluble organometallic Ru(II) complexes were synthesized and found to act as anticancer agents by catalyzing transfer hydrogenation reactions with biomolecules. The structure-activity relationship and reaction mechanism were investigated, and the compounds were also tested for their anticancer activity in vitro.
Article
Multidisciplinary Sciences
Shangpu Liu, Mikael Kepenekian, Stanislav Bodnar, Sascha Feldmann, Markus W. Heindl, Natalie Fehn, Jonathan Zerhoch, Andrii Shcherbakov, Alexander Poethig, Yang Li, Ulrich W. Paetzold, Aras Kartouzian, Ian D. Sharp, Claudine Katan, Jacky Even, Felix Deschler
Summary: This study reveals the unique photoluminescence properties of hybrid perovskite semiconductor materials, which can achieve high luminescence yields and circularly polarized photoluminescence at room temperature. The excellent photoluminescence performance is attributed to the suppression of nonradiative loss channels and the high rates of radiative recombination. These findings pave the way for high-performance solution-processed photonic systems and chiral-spintronic logic at room temperature.
Review
Materials Science, Multidisciplinary
Sebastian J. Weishaeupl, David C. Mayer, Yang Cui, Pushpendra Kumar, Harald Oberhofer, Roland A. Fischer, Jurgen Hauer, Alexander Poethig
Summary: This review presents recent advances in metal-organic frameworks (MOFs) and coordination polymers (CPs) regarding their response properties to multiphoton absorption (MPA). It covers the theoretical background of MPA absorbing linker molecules, the effect of excitonic coupling within a rigid framework assembly, and compares different scanning and non-scanning measurement techniques for two-photon absorption (TPA) spectroscopy. Additionally, it comprehensively presents the latest progress of linker-based MPA materials and their relationship with framework structure and MPA cross section.
JOURNAL OF MATERIALS CHEMISTRY C
(2022)
Article
Chemistry, Inorganic & Nuclear
Brech Aikman, Riccardo Bonsignore, Ben Woods, Daniel Doellerer, Riccardo Scotti, Claudia Schmidt, Alexandra A. Heidecker, Alexander Poethig, Edward J. Sayers, Arwyn T. Jones, Angela Casini
Summary: Research focused on designing new metallosupramolecular structures for drug delivery. Two self-assembled metal cages capable of encapsulating anticancer drugs have been synthesized and characterized. The stability and intracellular localization of these structures have been confirmed, and their antiproliferative activity has been investigated.
DALTON TRANSACTIONS
(2022)
Article
Chemistry, Inorganic & Nuclear
Max Klotzsche, Davide Barreca, Lorenzo Bigiani, Roberta Seraglia, Alberto Gasparotto, Laura Vanin, Christian Jandl, Alexander Poethig, Marco Roverso, Sara Bogialli, Gloria Tabacchi, Ettore Fois, Emanuela Callone, Sandra Dire, Chiara Maccato
Summary: A cobalt complex bearing fluorinated diketonate ligands and a diamine moiety was investigated as a potential Co molecular precursor for the CVD of Co3O4 systems, showing suitability for high-quality Co3O4 thin film fabrication.
DALTON TRANSACTIONS
(2021)
Article
Chemistry, Organic
Shengyang Guan, Thomas Pickl, Christian Jandl, Leon Schuchmann, Xiaoyu Zhou, Philipp J. Altmann, Alexander Pothig
Summary: Triazolate-based pillarplexes are a new type of supramolecular organometallic complexes with tubular pores, using a hybrid imidazolium/triazole cyclophane as a ligand precursor. These new pillarplexes show similarities to previously reported pyrazolate-based congeners, but exhibit unprecedented shape-adaptive behavior in the solid-state for the Au(i) complex, rationalized by DFT calculations. Additionally, complementary hydrogen bonding between cationic complexes is observed, demonstrating that rim modification not only modulates cavity flexibility, but also introduces further functionality into the SOC.
ORGANIC CHEMISTRY FRONTIERS
(2021)
