Article
Chemistry, Multidisciplinary
Nozomi Tomioka, Shinkoh Nanbu, Tomoyo Misawa-Suzuki, Hirotaka Nagao
Summary: Ruthenium complexes were oxidized by cerium sulfate to form new complexes through N-C bond formation between two aniline ligands and the ruthenium center.
Article
Chemistry, Multidisciplinary
Weirong Wu, Xufang Zhao, Guang Chen, Lingjun Liu, Yulin Li, Tao Chen, Tony D. James, Yuxia Liu
Summary: The Ni-catalyzed reactions of benzamides with bicyclic alkenes were investigated using DFT calculations. A novel N-H deprotonation circumventing catalytic mechanism was proposed, and the overlooked aspects of functionalized N,N-bidentate directing groups were pointed out to be useful for designing new catalytic reactions.
CHEMICAL COMMUNICATIONS
(2023)
Article
Chemistry, Inorganic & Nuclear
Suman Mallick, Purnananda Garu, Jagannath Chowdhury, Rajat Saha, Swarup Chattopadhyay
Summary: The synthesis of sulphido bridged dinuclear rhenium(III) complexes containing dithiocarbamato ligands is reported in this study, along with the spectral and electrochemical properties. The identity of a complex was confirmed through single-crystal X-ray structure determination. The electronic structure and absorption spectra of the complexes were analyzed using DFT and TD-DFT.
Article
Chemistry, Multidisciplinary
Jose Luis Borioni, Maria T. Baumgartner, Marcelo Puiatti, Liliana B. Jimenez
Summary: In this study, the specific reaction mechanism for the synthesis of 1-substituted perylenes was analyzed theoretically and experimentally. The anionic cyclodehydrogenation was found to take place from the binaphthyl dianion, and the O-substituted derivatives were unable to produce the required dianion.
Article
Chemistry, Inorganic & Nuclear
Li-Jie Fu, Bo-Hsun An, Chih-Hsuan Chou, Chi-Min Chen, Ching Tat To
Summary: A new family of rhodium porphyrin complexes with various perfluoroalkyl ligands has been successfully synthesized in good yields using commercially available perfluoroalkyl iodides and the air-stable precursor, suggesting a halogen atom transfer pathway with a rhodium(ii) porphyrin metalloradical through mechanistic investigations.
DALTON TRANSACTIONS
(2021)
Article
Chemistry, Organic
Meixia Liu, Huimin Hu, Runbo Sun, Haoyuan Li, Anjun Ding, Xiaoyong Liu, Zhengjiang Fu, Shengmei Guo, Hu Cai
Summary: We present a nickel-catalyzed reductive cross-coupling method to synthesize phosphinic amides from readily available nitroarenes and phosphine oxides. The reaction employs NiCl2/Xantphos as catalyst, zinc as reductant, and TMSCl as additive, delivering various phosphinic amides in moderate to good yields. Notably, a gram-scale synthesis was successfully achieved, making this method practical for the synthesis of phosphinic amides. Mechanistic insights were also obtained from control experiments.
ORGANIC CHEMISTRY FRONTIERS
(2023)
Article
Chemistry, Organic
Qin-Qiong Zeng, Yong-Qi Wang, Lang Cheng, Bi-Qin Wang, Ping Hu, Feijie Song
Summary: This tandem reaction involves Rh-catalyzed intramolecular annulation of benzocyclobutenols with alkynes followed by ZnCl2-promoted dehydration, providing an efficient strategy for the synthesis of 2H-furan, pyran, and oxepine-fused naphthalenes. The 2H-furan motif can also undergo a ring-opening reaction through Fe-catalyzed reductive C-O bond cleavage, enabling the formal intermolecular annulation of 2-hydroxybenzocyclobutenols with alkynes with complete regioselectivity in a two-step protocol.
Article
Chemistry, Organic
Zhan-Cai Li, Yu Zhang, Bing-Xia Yan, Xiao-Ning Wang, De-Hua Zhai, Qiang Li, Hong-Xing Zheng, Chang-Qiu Zhao
Summary: Biphenyl derived secondary phosphine oxides with 2'-hydroxyl were synthesized and converted to hydroxymethyl phosphine oxides. Chlorination and cyclization led to the formation of a series of P,O-heterocycles. Under LDA treatment, rearrangement occurred to stereoselectively produce hydroxyl substituted cyclic phosphines. The rearrangement was proposed to involve intra-molecular aromatic substitution reactions, resulting in the conversion of P-stereogenic secondary phosphine oxide to a P,C,axial-stereogenic P-cycle.
ORGANIC CHEMISTRY FRONTIERS
(2021)
Article
Chemistry, Physical
Xiaofang Su, Yongge Wei, Nana Ma, Hucheng Zhang, Likai Yan
Summary: The catalytic activity of Lindqvist-type hexamolybdate [Mo6O19]2- in the oxidation of an aniline derivative was studied. The formation of an N radical intermediate is influenced by the preassociation of [Mo6O19]2- and the substrate's highest occupied molecular orbital energy. The addition of Na2S2O3 increases the product yield, while Na2CO3 or K3PO4 deactivate the catalytic reaction.
JOURNAL OF PHYSICAL CHEMISTRY C
(2023)
Article
Chemistry, Applied
Haiyan Dong, Zhiyang Lin, Chuan Wang
Summary: In this protocol, reductive cobalt catalysis is used in the allylic defluorinative cross-electrophile coupling reaction between 1,1-difluoroalkyl halides and α-trifluoromethyl styrenes. This reaction shows a broad substrate scope (39 examples), good tolerance of various functionalities, and eliminates the need for pregenerating organometallics, providing a general method for synthesizing diverse organofluorines containing both a gem-difluoroalkene and a gem-difluoroalkane unit.
ADVANCED SYNTHESIS & CATALYSIS
(2023)
Article
Chemistry, Multidisciplinary
Nasser Nasser, Richard J. Puddephatt
Summary: Through crystallographic characterization, a mixture of gold(III) complexes, including an amide complex [AuCl2{& κ;2-N,N'-2-C5H4NC(=O)N(t-Bu)] and an aldolate complex [AuCl2{& κ;2-N,O-2-C5H4NCH(OMe)O)], was obtained by recrystallization of the oxaziridine derivative 2-t-butyl-3-(2-pyridinyl)oxaziridine with Na[AuCl4].2H2O from a solvent mixture containing methanol. It is suggested that these products are formed after O-N or C-N bond cleavage of the strained oxaziridine ring upon coordination to the gold(III) center. NMR spectroscopic monitoring showed that O-N bond cleavage of the oxaziridine ring was favored in the presence of a protic solvent. Coordination of an oxaziridine to gold(III) can result in N-O or C-O bond cleavage, yielding an amide or an aldolate complex of gold(III), respectively.
Article
Chemistry, Multidisciplinary
Fei Cong, Riccardo S. Mega, Jinhong Chen, Craig S. Day, Ruben Martin
Summary: In this study, we report a visible-light-mediated trifluoromethylation reaction of carbonyl-type compounds and unactivated olefins using copper as a catalyst. This reaction allows for the synthesis of valuable C(sp(3))-CF3 structures from easily accessible precursors under mild conditions, making it a complementary approach for late-stage functionalization.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Multidisciplinary Sciences
Qinglei Meng, Jiang Yan, Ruizhi Wu, Huizhen Liu, Yang Sun, Ningning Wu, Junfeng Xiang, Lirong Zheng, Jing Zhang, Buxing Han
Summary: Efficient production of benzene from lignin is of great importance but has not been realized. In this study, a strategy is developed to transform lignin into benzene over RuW/zeolite catalyst in water, with a high yield of 18.8% on lignin weight basis. This high-performance protocol paves the way for efficiently producing benzene using lignin as the feedstock.
NATURE COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Richard Y. Kong, Maria Batuecas, Mark R. Crimmin
Summary: This paper reports a homogeneous model system that constructs carbon chains from CO, showing a broad reactivity range and proposing a complete mechanism for chain growth. Variation of the transition metal fragment impacts both the rate of the steps of chain growth and the selectivity of carbon chain growth.
Article
Chemistry, Multidisciplinary
Chenglong Wang, Xianqing Wu, Haiyan Li, Jingping Qu, Yifeng Chen
Summary: A nickel-catalyzed three-component carbonylative cross-coupling reaction has been developed for the efficient synthesis of broad range of beta,gamma-unsaturated ketones at atmospheric pressure. Furthermore, the chemoselective allylic carbonylation of diols demonstrates the practicality of this method. The use of organoalanes as both coupling components and activators for alcohol functionalization is crucial, eliminating the need for extraneous activators.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Physical
Samik Acharyya, Saswati Gharami, Deblina Sarkar, Paramita Ghosh, Nabendu Murmu, Tapan Kumar Mondal
Summary: The new fluorescence probe H2L shows efficient and selective detection of Zn(II), with low toxicity and potential for live cell imaging.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Chemistry, Analytical
Lakshman Patra, Krishnendu Aich, Saswati Gharami, Tapan Kumar Mondal
Summary: The fluorogenic probe COUBM is designed for rapid detection of phosgene in both solution and gas phase. It reacts with phosgene to form a carbamylated product, resulting in a sharp increase in fluorescence intensity. The probe can efficiently detect phosgene in vapor phase using a COUBM loaded filter paper kit, and theoretical calculations are performed to interpret the electronic structure and sensing mechanism.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Multidisciplinary
Akash Das, Moumita Saha, Subrata Mandal, Sanjib Das, Krishna Das Saha, Tapan K. Mondal
Summary: New Pd(ii) and Pt(ii) complexes with an O,N,S donor azo-thioether pincer ligand were synthesized and characterized. The X-ray structures of the complexes showed distorted square planar geometry. DFT and TDDFT calculations were used to interpret the electronic structures and spectral properties. The interaction of the complexes with CT-DNA and BSA proteins was studied using absorption and fluorescence methods. The complexes effectively quenched DNA bound ethidium bromide and the intrinsic fluorescence of BSA protein through static quenching. The high binding constants obtained from the DNA binding studies led to in vitro cytotoxicity assays of the complexes in different human cancer cell lines, showing lower half maximal inhibitory concentrations compared to cisplatin.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Applied
Biswajit Bera, Sanchaita Mondal, Subrata Mandal, Krishna Das Saha, Tapan K. Mondal
Summary: New Pd(II) and Pt(II) complexes with a O,N,N donor pincer ligand were synthesized and characterized. The complexes' interaction with bovine serum albumin protein was assessed using absorption and fluorescence techniques. The antiproliferative activity of the complexes on several cancer cell lines, as well as a normal cell line, was investigated. The results showed that both complexes exhibited better antiproliferative activity on the HepG2 cell line, and complex C2 showed higher cytotoxicity than C1. Morphological changes and fragmented DNA confirmed that cell death occurred through apoptosis.
APPLIED ORGANOMETALLIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Biswajit Bera, Subrata Mandal, Saswati Gharami, Tapan Kumar Mondal
Summary: In this study, three novel luminescent metal complexes were synthesized and found to efficiently detect 2,4,6-trinitrophenol (TNP) and other nitroaromatic-based explosives (NACs). The complexes showed high selectivity and sensitivity towards TNP and their fluorescence signals were quenched in the presence of different NACs. The detection ability of the complexes for TNP was also tested in real samples, with complex 3 showing the best performance. The interaction mechanism between the complexes and TNP was further investigated using spectroscopic techniques.
CRYSTAL GROWTH & DESIGN
(2023)
Article
Chemistry, Multidisciplinary
Subrata Mandal, Rahul Naskar, Rimi Mukherjee, Apurba Sau Mondal, Akash Das, Nabendu Murmu, Tapan K. Mondal
Summary: This research investigates the synthesis, characterization, bio, catalytic and anticancer activities of a novel copper complex. It also explores the complex's binding properties to DNA and protein, as well as its cytotoxicity against cancer cells.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Analytical
Amitav Biswas, Debarpan Mitra, Rahul Naskar, Atanu Maji, Akash Das, Nabendu Murmu, Tapan Kumar Mondal
Summary: A chemosensor (HBMC) based on diversified biphenyl thiosemicarbazide has been developed for detecting Cd2+ in a MeOH : H2O (4 : 1) solution. The sensor showed a chromogenic change from colorless to light yellow and a turn-on fluorogenic change from non-fluorescent to blooming cyan. It exhibited a sharp turn-on emission for Cd2+ with a 16 fold increase in fluorescence intensity value at 496 nm. The mechanism for Cd2+ sensing involved inhibition of C = N isomerization and ESIPT process, as well as the chelation enhanced fluorescence process. HBMC displayed a detection limit of 10(-8) (M) and demonstrated cell permeability and biocompatibility in detecting Cd2+ in human breast cancer cells (MDA-MB-231).
ANALYTICAL METHODS
(2023)
Article
Chemistry, Multidisciplinary
Atanu Maji, Amitav Biswas, Akash Das, Saswati Gharami, Krishnendu Aich, Tapan K. Mondal
Summary: A novel colorimetric and fluorescent sensing probe CBTA was synthesized and characterized. The probe showed selective turn off fluorescence in the presence of cyanide in a DMSO : H2O medium. The turn off fluorescence response mechanism was attributed to the nucleophilic attack of cyanide ions at the cyano vinyl group of the probe.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Subrata Mandal, Rahul Naskar, Apurba Sau Mondal, Biswajit Bera, Tapan K. K. Mondal
Summary: In this study, the synthesis, structure determination, enzyme-like activities, and biomolecular interactions of three mononuclear copper(II) complexes were investigated. These complexes showed high binding affinities to DNA and proteins, and demonstrated good enzyme activity. Among them, complex 3 exhibited the highest efficacy.
DALTON TRANSACTIONS
(2023)
Article
Chemistry, Multidisciplinary
Rahul Naskar, Paramita Ghosh, Subrata Mandal, Subrata Jana, Nabendu Murmu, Tapan Kumar Mondal
Summary: A new palladium(II) complex, [Pd(LSEt)Cl] (C1), was synthesized and found to have strong binding affinity with CT DNA and BSA protein, as well as low cytotoxicity towards human gastric cancer cell lines (AGS).
JOURNAL OF CHEMICAL SCIENCES
(2022)
Article
Chemistry, Multidisciplinary
Rahul Naskar, Saswati Gharami, Subrata Mandal, Tapan Kumar Mondal
Summary: A new chromone-based fluorescent probe (HMPM) was developed for the selective detection of Pd2+. The probe showed ratiometric fluorescence enhancement and could be effectively used for Pd2+ detection by a dip-stick method.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Physical
Sangita Das, Lakshman Patra, Partha Pratim Das, Kakali Ghoshal, Saswati Gharami, James W. Walton, Maitree Bhattacharyya, Tapan Kumar Mondal
Summary: A new ratiometric fluorescent probe HQCN was synthesized for the selective detection of hydrazine and hypochlorite ions. The study revealed distinct response characteristics of HQCN towards hydrazine and hypochlorite ions, as observed from fluorescence and UV-Vis spectroscopy. The chemodosimetric experiments demonstrated that HQCN can detect hydrazine and hypochlorite ions at concentrations as low as 10(-8)M. The fluorescence imaging experiments also confirmed the ability of HQCN to monitor the presence of hydrazine and hypochlorite ions in human peripheral blood cells.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2022)
Article
Chemistry, Multidisciplinary
Apurba Sau Mondal, Rahul Naskar, Chandan Kumar Manna, Tapan Kumar Mondal
Summary: An octahedral Mn(II) complex, [Mn(L)(2)], was synthesized using a redox active ONS donor pincer ligand, 3-(2-(2-(methylthio)phenyl)hydrazono)pentane-2,4-dione (HL). The complex was characterized through various spectroscopic methods and its geometry was confirmed using single-crystal X-ray diffraction. Theoretical calculations were performed to explain the electronic structure of [Mn(L)(2)]. The cyclic voltammogram of [Mn(L)(2)] showed reversible Mn(II)/Mn(III) oxidation and ligand-based reduction.
JOURNAL OF CHEMICAL SCIENCES
(2022)
Article
Chemistry, Multidisciplinary
Biswajit Bera, Sanchaita Mondal, Saswati Gharami, Rahul Naskar, Krishna Das Saha, Tapan K. Mondal
Summary: New Pd(II) and Pt(II) complexes with ONN donor pincer ligand have been synthesized and characterized. These complexes showed antiproliferative activity against different human cancer cell lines, with high cytotoxicity observed in HepG2 cell line. However, they exhibited low cytotoxicity towards human peripheral blood mononuclear cells. The cytotoxicity of Pt(II) complex was comparable to cisplatin in HepG2 cell lines.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Saswati Gharami, Krishnendu Aich, Paramita Ghosh, Lakshman Patra, Nabendu Murmu, Tapan K. Mondal
DALTON TRANSACTIONS
(2020)