Article
Biochemistry & Molecular Biology
Iala Milene Bertasso, Egberto Gaspar de Moura, Carla Bruna Pietrobon, Suelen Silva Cabral, George Eduardo Gabriel Kluck, Georgia Correa Atella, Alex Christian Manhaes, Patricia Cristina Lisboa
Summary: Maternal protein-restricted diet during lactation may affect hepatic metabolism in offspring without inducing hepatic lipid accumulation. Female offspring showed normal hepatic morphology, while male offspring had no liver steatosis.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2022)
Article
Agriculture, Dairy & Animal Science
Ittipong Khamtawee, Komsit Singdamrong, Pradubdao Tatanan, Pavarisa Chongpaisarn, Natchanon Dumniem, Pachara Pearodwong, Junpen Suwimonteerabutr, Morakot Nuntapaitoon, Padet Tummaruk
Summary: Cinnamon oil supplementation in the lactation diet can increase daily feed intake of multiparous sows and decrease pre-weaning piglet mortality in a tropical environment.
Article
Biochemistry & Molecular Biology
Amelia R. Tanner, Cameron S. Lynch, Victoria C. Kennedy, Asghar Ali, Quinton A. Winger, Paul J. Rozance, Russell Anthony
Summary: CSH RNA interference resulted in reduced fetal and uterine weights, decreased umbilical blood flow, lower umbilical IGF1 concentrations, and decreased nutrient uptake. These findings suggest that CSH is essential for facilitating adequate blood flow for the uptake of essential oxygen, oxidative substrates, and hormones to support fetal and uterine growth.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Endocrinology & Metabolism
Hong Yang, Nan Chen, Lei Fan, Xiaojing Lin, Juncheng Liu, Yuehua You, Ying Zhong, Yan Chen, Jibin Li, Xiaoqiu Xiao
Summary: Maternal high-fat diet during pregnancy and lactation has long-term effects on the pathogenesis of obesity in offspring, and the early postnatal stage is a critical window for metabolic programming.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Editorial Material
Biochemistry & Molecular Biology
Gloria Garrabou, Ana Sandra Hernandez, Mariona Guitart-Mampel, Elena Escalada-Casellas, Gemma Malats-Revelles, Sara Castro-Barquero, Ana Maria Ruiz-Leon, Kilian Vellve, Rosa Casas, Francesc Cardellach, Fatima Crispi, Francesc Josep Garcia-Garcia
Summary: This study found that dietary interventions, including supplementation with hydroxytyrosol, can improve complications of IUGR. Additionally, early biomarkers combined with dietary interventions may help predict IUGR diagnosis, aiding in avoiding risks of newborn mortality and morbidity.
Article
Veterinary Sciences
Karina G. Orquera-Arguero, Isabel Casasus, Javier Ferrer, Mireia Blanco
Summary: Lactating cows utilize different adaptation strategies to cope with nutritional challenges as lactation advances. Body fat mobilization predominates in early lactation, while protein catabolism prevails at later stages. Feed restriction induces milk yield loss, decreased milk protein, and increased milk urea contents to different extents. Plasma metabolite concentrations are also affected, with NEFA concentrations rising during feed restriction and BHB and urea concentrations increasing only in certain lactation months.
RESEARCH IN VETERINARY SCIENCE
(2023)
Article
Geriatrics & Gerontology
Susan B. Racette, Valene Garr Barry, Connie W. Bales, Megan A. McCrory, Kathleen A. Obert, Cheryl H. Gilhooly, Susan B. Roberts, Corby K. Martin, Catherine Champagne, Sai Krupa Das
Summary: The study aimed to assess the nutritional adequacy of long-term calorie-restricted (CR) diets. The results showed that calorie-restricted diets were nutritionally equivalent or superior to ad libitum diets in terms of nutritional adequacy and diet quality among adults without obesity.
EXPERIMENTAL GERONTOLOGY
(2022)
Article
Biology
Ana Heras-Molina, Natalia Yeste, Jose Luis Pesantez-Pacheco, Susana Astiz, Marta Vazquez-Gomez, Arianna Bettiga, Francesco Trevisani, Consolacion Garcia-Contreras, Sergio Luis-Lima, Anna Bassols, Esteban Porrini, Antonio Gonzalez-Bulnes
Summary: The study explores the adult phenotype of offspring with low birth weight induced by maternal malnutrition or placental insufficiency, using a swine model. The findings suggest that low birth weight offspring can achieve similar obesity in adulthood as normal birth weight offspring when exposed to a fattening diet and glucose metabolism is more compromised in obese low birth weight pigs than obese normal birth weight pigs.
Article
Clinical Neurology
Tai-Ho Hung, Yu-Cheng Liu, Chun-Hu Wu, Chien-Cheng Chen, Hsien Chao, Feng-Yi Yang, Szu-Fu Chen
Summary: This study suggests that antenatal LIPUS treatment may reduce brain injury in IUGR by enhancing BDNF/CaMKII/Akt signaling, leading to increased neuronal number and myelin protein expression, and attenuated neurodevelopmental deficits. These effects are associated with upregulation of BDNF and PlGF protein expression in the brain and enhanced production of glucose transporter 1 and BDNF in the placenta.
Article
Veterinary Sciences
Michaela Fels, Lilith Schrey, Sally Rauterberg, Nicole Kemper
Summary: The study showed that early socialized piglets exhibited better social skills after mixing, resulting in reduced fighting and injuries.
Review
Immunology
Nicholas Collins, Yasmine Belkaid
Summary: Nutrition plays a profound role in shaping the immune system, with mild reductions in dietary intake enhancing protective immunity and limiting aberrant inflammatory responses. In severe nutritional stress, specific immunological functions are heightened to prioritize survival.
Review
Nutrition & Dietetics
Aneesa Z. Zaidi, Sophie E. Moore, Sandra G. Okala
Summary: Maternal nutritional supplementation during pregnancy and lactation may alter the infant gut or breastmilk microbiota. Probiotic supplementation generally results in probiotic colonization of infant gut microbiota.
Review
Biochemistry & Molecular Biology
Stephanie E. O'Hara, Kelly M. Gembus, Lisa M. Nicholas
Summary: Exposure to compromised nutritional environment during early life may lead to long-term consequences such as increased risk of type 2 diabetes and obesity in adult offspring. Studies focus on understanding the impact of these exposures on islet morphology and beta-cell function to determine the mechanisms behind the increased risk of diabetes in offspring.
Article
Multidisciplinary Sciences
S. Cortellino, V. Quagliariello, G. Delfanti, O. Blazevits, C. Chiodoni, N. Maurea, A. Di Mauro, F. Tatangelo, F. Pisati, A. Shmahala, S. Lazzeri, V. Spagnolo, E. Visco, C. Tripodo, G. Casorati, P. Dellabona, V. D. Longo
Summary: This study explores the use of periodic cycles of a fasting-mimicking diet (FMD) to reduce the side effects caused by immunotherapy in cancer treatment. The combination of FMD cycles with immunotherapy shows promising results in delaying cancer growth and reducing cardiotoxicity.
NATURE COMMUNICATIONS
(2023)
Article
Multidisciplinary Sciences
Marcela Parra, Jiyeon Yang, Megan Weitner, Mustafa Akkoyunlu
Summary: The study found that the lack of PABA in maternal milk may provide protection against malaria infection in newborn mice, delaying and reducing the onset of parasitemia. Mice fed with a PABA-deficient diet after weaning were still able to control parasitemia and developed robust T follicular helper responses, providing protection against a second challenge with Plasmodium yoelii.
SCIENTIFIC REPORTS
(2021)
Article
Food Science & Technology
Penelope Lacrisio Reis Menta, Maria Emilia Rabelo Andrade, Livia Furquim de Castro, Luisa Martins Trindade, Melissa Tainan Silva Dias, Josiane Erica Miyamoto, Raisa Magno dos Santos, Geovanni Dantas Cassali, Raquel Franco Leal, Ana Paula Badan Ribeiro, Renato Grimaldi, Leticia Martins Ignacio-Souza, Marcio Alberto Torsoni, Adriana Souza Torsoni, Valbert Nascimento Cardoso, Marciane Milanski
Summary: The study suggests that adding interesterified fat to a normal lipid diet may have adverse effects on intestinal mucosa, leading to increased intestinal permeability, bacterial translocation, and damage to the intestinal epithelium.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Biochemistry & Molecular Biology
Carolina Panzarin, Lais Angelica de Paula Simino, Mariana Camargo Silva Mancini, Leticia Martins Ignacio-Souza, Marciane Milanski, Marcio Alberto Torsoni, Adriana Souza Torsoni
Summary: The modulation of hepatic miR-370-122-Let7 miRNA may play a crucial role in the early stages of NAFLD, preceding changes in glycemic homeostasis and adiposity.
MOLECULAR BIOLOGY REPORTS
(2022)
Article
Public, Environmental & Occupational Health
T. Fante, L. A. P. Simino, Marina Figueiredo Fontana, Andressa Reginato, Thomaz Guadagnini Ramalheira, Hosana Gomes Rodrigues, Patricia Cristina Lisboa, Egberto Gaspar de Moura, Leticia Martins Ignacio-Souza, Marciane Milanski, Marcio Alberto Torsoni, Adriana Souza Torsoni
Summary: Offspring of obese dams are more susceptible to developing nonalcoholic fatty liver disease but are programmed to be protected from the damage promoted by a high fat diet, despite a lower impact on survival rate after surgery.
JOURNAL OF DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE
(2022)
Article
Dentistry, Oral Surgery & Medicine
Renato Assis Machado, Ana Lucia Carrinho Ayroza Rangel, Silvia Regina de Almeida Reis, Rafaela Scariot, Ricardo D. Coletta, Hercilio Martelli-Junior
Summary: This study provides evidence for the association of rs34246903 (4p16.2) with non-syndromic cleft lip with or without cleft palate (NSCL +/- P), as well as for the association of rs13317 within FGFR1 with NSCL +/- P, in a multiethnic Brazilian population.
ARCHIVES OF ORAL BIOLOGY
(2022)
Article
Mycology
Daniel G. Ubiali, Asheley H. B. Pereira, Fabiana M. Boabaid, Valeria Dutra, Luciano Nakazato, Camila G. Campos, Edson M. Colodel, Caroline A. Pescador, Franklin Riet-Correa
Summary: Potassium iodide therapy may treat rhinofacial pythiosis in sheep. This study examined 13 sheep with rhinofacial pythiosis and found that 84.6% of treated sheep demonstrated complete recovery after being treated with 10 ml of 10% potassium iodide solution orally every day for an average of 85 days.
JOURNAL DE MYCOLOGIE MEDICALE
(2022)
Article
Pathology
Asheley H. B. Pereira, Anna L. Vasconcelos, Victoria L. B. Silva, Beatriz S. Nogueira, Anna C. P. Silva, Richard C. Pacheco, Marcos A. Souza, Edson M. Colodel, Daniel G. Ubiali, Alexander W. Biondo, Luciano Nakazato, Valeria Dutra
Summary: This study reports the first case of natural SARS-CoV-2 infection in a New World monkey, a free-ranging adult female black-tailed marmoset. Pathological examination revealed the presence of viral proteins in the lungs, liver, spleen, lymph nodes, and large intestine.
JOURNAL OF COMPARATIVE PATHOLOGY
(2022)
Review
Dentistry, Oral Surgery & Medicine
Fernanda Veiga Rodeiro Nery, Daniel Adrian Silva Souza, Juliana Borges de Lima Dantas, Gabriela Botelho Martins, Silvia Regina de Almeida Reis, Alena Ribeiro Alves Peixoto Medrado
Summary: Although patients with psoriasis may have oral lesions, these lesions are not specific to psoriasis. Further epidemiological studies are needed to investigate the association between psoriasis and possible changes in the oral mucosa.
SPECIAL CARE IN DENTISTRY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Gabriela da Silva Lopes, Lais Guimaraes, Eduarda Nascimento, Deborah Q. Freitas, Ieda Rebello, Alena P. Medrado, Ricardo D. Coletta, Silvia R. A. Reis
Summary: This study assessed the degree of root curvature in patients with non-syndromic cleft lip and/or palate (NSCL/P). The results showed differences in root curvature between the NSCL/P group and the control group, with higher frequencies of mild and moderate curvature in premolars and molars in the cleft group. The location of the curvature also differed, with inclination observed more frequently in the apical third of the root in the cleft group and in the medial third in the control group. These differences should be considered in the dental treatment planning of patients.
CLEFT PALATE-CRANIOFACIAL JOURNAL
(2022)
Article
Dentistry, Oral Surgery & Medicine
Lilianny Querino Rocha de Oliveira, Hellen Carolliny de Souza Nicolau, Daniella Reis Barbosa Martelli, Hercilio Martelli-Junior, Rafaela Scariot, Ana Lucia Carrinho Ayroza Rangel, Silvia Regina de Almeida Reis, Ricardo D. Coletta, Renato Assis Machado
Summary: This study evaluated the association of BMP4 tag-SNPs and SNP-SNP interactions with the susceptibility of nonsyndromic orofacial clefts in the Brazilian population. Significant associations were found between rs2761887 and risk for nonsyndromic cleft lip with or without cleft palate in patients with high African genomic ancestry. Additionally, significant SNP-SNP interactions involving other genes were identified, increasing the risk for nonsyndromic cleft lip.
CLEFT PALATE CRANIOFACIAL JOURNAL
(2023)
Article
Veterinary Sciences
David J. F. Silva, Janaina M. A. R. Moreira, Marlon Ribeiro, Fernanda H. Maruyama, Thais O. Morgado, Luciano Nakazato, Valeria Dutra, Marcos A. Souza, Edson M. Colodel
Summary: In May 2021, a neotropical porcupine from Brazil was diagnosed with a lethal poxviral infection caused by the Brazilian porcupinepox virus (BPoPV). The infection resulted in erythema, exfoliative dermatitis, and erosions on the face, hindlimb, and vulva. Histological examination revealed proliferative and necrotic dermatitis with intraepidermal and follicular pustules, as well as intracytoplasmic inclusion bodies. Phylogenetic analysis showed that the BPoPV strains were closely related to other poxviruses that infect rodents. The impact of this poxviral infection on species conservation and its potential for spillover into humans and other vertebrates remain unknown.
JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION
(2023)
Article
Infectious Diseases
Stefhano Luis Candido, Nathalia de Assis Pereira, Maria Julia de Oliveira Rosa Fonseca, Richard de Campos Pacheco, Thais Oliveira Morgado, Edson Moleta Colodel, Luciano Nakazato, Valeria Dutra, Thallitha Samih Wischral Jayme Vieira, Daniel Moura de Aguiar
Summary: This study investigated the interaction between neotropical primates and the Anaplasmataceae family. DNA fragments similar to Ehrlichia canis were detected in Sapajus apella and Ehrlichia chaffeensis in Mico melanurus. Moreover, an Anaplasma sp. closely related to Anaplasma marginale was identified in two S. apella individuals. These findings highlight the susceptibility of neotropical primates to Anaplasmataceae agents, which are transmitted by ticks and can also infect other animals, including humans.
TICKS AND TICK-BORNE DISEASES
(2023)
Article
Veterinary Sciences
Leandro S. Rocha, Aruaque L. F. Oliveira, Felipe P. Arruda, Leticia C. Pitchenin, Valeria Dutra, Luciano Nakazato, Fernando H. Furlan, Edson M. Colodel
Summary: Glanders is a disease primarily affecting horses, mules, and donkeys, caused by Burkholderia mallei. The disease can cause skin, lung, and organ lesions, but often remains asymptomatic. In Brazil, serological tests are used to detect antibodies against B. mallei, but the mandatory euthanasia of seroreactive animals has led to conflicts among breeders, veterinarians, and diagnostic laboratories.
PESQUISA VETERINARIA BRASILEIRA
(2023)
Article
Veterinary Sciences
Cristiane Trevisan Viana de Souza, Daniela Souza Prass, Roberto Lopes Souza, Fernando Henrique Furlan, Edson Moleta Colodel, Alessandra Tammy Hayakawa Ito de Sousa, Valeria Dutra, Valeria Regia Franco Sousa
Summary: This paper describes a case of generalized lymphadenomegaly caused by Mycobacterium intracellulare infection in a male dog in Brazil. The diagnosis was confirmed through cytological, histopathological, and molecular findings. Treatment was prescribed, but the dog suffered a pelvic fracture due to a car accident and was euthanized.
ACTA SCIENTIAE VETERINARIAE
(2022)
Article
Pathology
Ana Carla Barletta Sanches, Alessandra Lais Pinho Valente Pires, Alena Ribeiro Alves Peixoto Medrado, Silvia Regina de Almeida Reis, Valeria Souza Freitas, Gabriela Botelho Martins
Summary: This study aimed to verify the association between white and red lesions and histomorphometric characteristics of OLP lesions. The results showed no associations between white and red OLP lesions and the histomorphometric characteristics evaluated.
HEAD & NECK PATHOLOGY
(2022)
Article
Toxicology
Samar Afif Jarrah, Louise Bach Kmetiuk, Otavio Valerio de Carvalho, Alessandra Tammy Hayakawa Ito de Sousa, Valeria Regia Franco Souza, Luciano Nakazato, Edson Moleta Colodel, Andrea Pires Dos Santos, Christina Pettan-Brewer, Rosane Christine Hahn, Renata Dezengrini Slhessarenko, Daniel Guimaraes Ubiali, Asheley Henrique Barbosa Pereira, Helio Autran de Morais, Alexander Welker Biondo, Valeria Dutra
Summary: This study found that viral antigens may be detected by immunohistochemistry in multiple organs six weeks after infection, despite negative results by RT-PCR testing.
JOURNAL OF VENOMOUS ANIMALS AND TOXINS INCLUDING TROPICAL DISEASES
(2022)