The synthetic glycolipid-based TLR4 antagonist FP7 negatively regulates in vitro and in vivo haematopoietic and non-haematopoietic vascular TLR4 signalling

Structure–Activity Relationship in Monosaccharide-Based Toll-Like Receptor 4 (TLR4) Antagonists

(2018) Fabio A. Facchini et al.   JOURNAL OF MEDICINAL CHEMISTRY

TLR4 antagonist FP7 inhibits LPS-induced cytokine production and glycolytic reprogramming in dendritic cells and protects mice from lethal influenza infection

(2017) Laure Perrin-Cocon et al.   Scientific Reports

The Role of HMGB1 in Cardiovascular Biology: Danger Signals

(2015) Jingjing Cai et al.   ANTIOXIDANTS & REDOX SIGNALING

A novel small molecule TLR4 antagonist (IAXO-102) negatively regulates non-hematopoietic toll like receptor 4 signalling and inhibits aortic aneurysms development

(2015) Christopher Huggins et al.   ATHEROSCLEROSIS

The Many Alternative Faces of Macrophage Activation

(2015) David A. Hume   Frontiers in Immunology

Modulation of CD14 and TLR4⋅MD-2 Activities by a Synthetic Lipid A Mimetic

(2013) Roberto Cighetti et al.   CHEMBIOCHEM

Elevation of Plasma High-Density Lipoproteins Inhibits Development of Experimental Abdominal Aortic Aneurysms

(2012) Evelyn Torsney et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Rosiglitazone negatively regulates c-Jun N-terminal kinase and toll-like receptor 4 proinflammatory signalling during initiation of experimental aortic aneurysms

(2012) Grisha Pirianov et al.   ATHEROSCLEROSIS

Toll-like Receptor Signaling Pathways in Cardiovascular Diseases: Challenges and Opportunities

(2012) Faezeh Moghimpour Bijani et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Bacterial Sensing, Cell Signaling, and Modulation of the Immune Response During Sepsis

(2012) Reinaldo Salomao et al.   SHOCK

MyD88 Deficiency Attenuates Angiotensin II-Induced Abdominal Aortic Aneurysm Formation Independent of Signaling Through Toll-Like Receptors 2 and 4

(2011) A. Phillip Owens et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Influence of Severity of Illness on the Effects of Eritoran Tetrasodium (E5564) and on Other Therapies for Severe Sepsis

(2011) Andre C. Kalil et al.   SHOCK

Biomarkers as end points in clinical trials of severe sepsis: A garden of forking paths*

(2010) Jorge I. F. Salluh et al.   CRITICAL CARE MEDICINE

Evidence of a Specific Interaction between New Synthetic Antisepsis Agents and CD14

(2009) Matteo Piazza et al.   BIOCHEMISTRY

Glycolipids and Benzylammonium Lipids as Novel Antisepsis Agents: Synthesis and Biological Characterization

(2009) Matteo Piazza et al.   JOURNAL OF MEDICINAL CHEMISTRY

A novel method for production of lipid hydroperoxide- or oxysterol-rich low-density lipoprotein

(2007) Andrew B. Gerry et al.   ATHEROSCLEROSIS

Toll-Like Receptor 4 Mediates Maladaptive Left Ventricular Remodeling and Impairs Cardiac Function After Myocardial Infarction

(2007) Leo Timmers et al.   CIRCULATION RESEARCH