TLR4-mediated pro-inflammatory dendritic cell differentiation in humans requires the combined action of MyD88 and TRIF

Dual Signaling of MyD88 and TRIF Is Critical for Maximal TLR4-Induced Dendritic Cell Maturation

(2014) H. Shen et al.   JOURNAL OF IMMUNOLOGY

Genetic variation in Toll-like receptors and disease susceptibility

(2012) Mihai G Netea et al.   NATURE IMMUNOLOGY

Selective TRIF-Dependent Signaling by a Synthetic Toll-Like Receptor 4 Agonist

(2012) W. S. Bowen et al.   Science Signaling

Regulation of Lipopolysaccharide-Induced Translation of Tumor Necrosis Factor-Alpha by the Toll-Like Receptor 4 Adaptor Protein TRAM

(2011) Lijian Wang et al.   Journal of Innate Immunity

Synergy Between Viral and Bacterial Toll-Like Receptors Leads to Amplification of Inflammatory Responses and Preterm Labor in the Mouse1

(2010) Vladimir Ilievski et al.   BIOLOGY OF REPRODUCTION

MyD88-dependent TLR4 signaling is selectively impaired in alveolar macrophages from asymptomatic HIV+ persons

(2010) S. D. Tachado et al.   BLOOD

Monophosphoryl lipid A plus IFNγ maturation of dendritic cells induces antigen-specific CD8+ cytotoxic T cells with high cytolytic potential

(2010) Anja ten Brinke et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

TRIF Signaling Stimulates Translation of TNF-  mRNA via Prolonged Activation of MK2

(2010) P. Gais et al.   JOURNAL OF IMMUNOLOGY

Release of IL-12 by dendritic cells activated by TLR ligation is dependent on MyD88 signaling, whereas TRIF signaling is indispensable for TLR synergy

(2010) Mathias Krummen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Multiple signaling pathways contribute to synergistic TLR ligand-dependent cytokine gene expression in human monocyte-derived macrophages and dendritic cells

(2009) S. M. Makela et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Roles for LPS-dependent interaction and relocation of TLR4 and TRAM in TRIF-signaling

(2008) Natsuko Tanimura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β

(2008) Jonathan C Kagan et al.   NATURE IMMUNOLOGY