Article
Engineering, Environmental
Amin Piri, Hyeong Rae Kim, Dae Hoon Park, Jungho Hwang
Summary: Airborne virus susceptibility is a major cause of severe respiratory diseases worldwide, emphasizing the need to develop rapid and accurate monitoring and diagnostic approaches for emerging infections. The study found that using a sampling solution of PBS+AA can effectively reduce oxidative damage to viral RNA and protein, thereby increasing virus survivability during sampling.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Review
Public, Environmental & Occupational Health
Yasir Almuzaini, Marriyah Alburayh, Ahmed Alahmari, Fahad Alamri, Abdulrahman Y. Sabbagh, Majid Alsalamah, Anas Khan
Summary: This study utilized the Haddon matrix and combined model to identify risk factors of heat-related illnesses and implement prevention strategies. By comprehensively assessing the risk factors and preventive measures, the impact of heat-related illnesses on health can be effectively mitigated.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Respiratory System
Yangqing Zhan, Xiaojuan Chen, Weijie Guan, Wenda Guan, Chunguang Yang, Sihua Pan, Sook-San Wong, Rongchang Chen, Feng Ye
Summary: This study investigated the clinical impacts of a nosocomial outbreak of A(H1N1)pdm09 in a hospital between January 21 and February 17, 2016. The outbreak was limited to eight patients in one ward after the implementation of an infection control measure bundle, with all patients recovering after treatment. Infected patients experienced a delay in discharge and excess costs, but there were no deaths reported.
JOURNAL OF THORACIC DISEASE
(2021)
Article
Biochemical Research Methods
Hongyu Zhou, Shengjun Bu, Yao Xu, Lulu Xue, Zhongyi Li, Zhuo Hao, Jiayu Wan, Feng Tang
Summary: This study presents a colorimetric biosensor for detecting H1N1 influenza virus using the CRISPR/Cas13a system and hybridization chain reaction (HCR). The biosensor exhibited excellent specificity and sensitivity, with a linear relationship ranging from 10 pM to 100 nM and a detection limit of 0.152 pM. This new and sensitive detection method holds promise as a rapid diagnostic test for influenza virus.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Infectious Diseases
Laurent Coudeville, Amine Amiche, Ashrafur Rahman, Julien Arino, Biao Tang, Ombeline Jollivet, Alp Dogu, Edward Thommes, Jianhong Wu
Summary: The study found that the Hajj pilgrimage has a significant impact on the transmission of invasive meningococcal disease (IMD), affecting both pilgrims and the local population. Quadrivalent ACWY vaccination was found to be highly effective in reducing the risk of outbreaks during Hajj.
BMC INFECTIOUS DISEASES
(2022)
Article
Infectious Diseases
Frieder Schaumburg, Neele Frobose, Robin Kock
Summary: The study found that the GI-EB Screening assay used for diagnosing traveller's diarrhoea failed to establish a clear association between various test-target organisms (such as Campylobacter spp., Clostridioides difficile toxin A/B, etc.) and diarrhoea. Although it showed a concordance of 86.8-100% with the BioFire (R) FilmArray (R), its selection of test-target organisms seems inappropriate for the diagnosis of TD.
BMC INFECTIOUS DISEASES
(2021)
Article
Biochemical Research Methods
Weidu Song, Chuanhao Zhang, Huichao Lin, Taiyi Zhang, Haixia Liu, Xiaowen Huang
Summary: The proposed real-time rotary PCR reaction system (RRP) meets the requirements of low cost, low-power consumption, potential for miniaturization, and portability. Experimental and theoretical results demonstrate its feasibility in the rapid quantitative detection of Pseudomonas aeruginosa and have broad application prospects in bacteria detection and food safety.
Article
Biochemical Research Methods
Shaolei Huang, Yiquan An, Bangchao Xi, Xianglian Gong, Zhongfu Chen, Shan Shao, Shengxiang Ge, Jun Zhang, Dongxu Zhang, Ningshao Xia
Summary: Nucleic acid detection is a method that directly identifies the presence of pathogenic microorganisms and has advantages of high sensitivity, commendable specificity, and a short window period. A real-time PCR system based on multiple temperature zones was proposed to solve the time-consuming problem, enabling fast detection speed and high sensitivity under extreme conditions.
Article
Nanoscience & Nanotechnology
Seong Uk Son, Eun-Kyung Lim, Soojin Jang, Jaewoo Lim, Seung Beom Seo, Taejoon Kang, Juyeon Jung, Seo Yeong Oh, Sun-Woo Yoon, Dongeun Yong, Jaejong Lee
Summary: The study developed a conductive thread-based immunosensor to easily detect airborne viruses, which is important in preventing the spread of infectious diseases.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Public, Environmental & Occupational Health
Ludovic Phalippou, Dayin Zhang
Summary: In June 2020, the U.S. experienced a surge in COVID-19 cases, unlike other parts of the world. This coincided with the largest mass protests in U.S. history. The study shows that areas with more protests had the highest increase in COVID-19 cases, even after controlling for other factors. The research also found that good weather during the protests led to more people attending and subsequently more COVID-19 cases and deaths.
SSM-POPULATION HEALTH
(2023)
Article
Multidisciplinary Sciences
Jae Jong Kim, Hyoung-Min Park, A. Young Kyoung, In Kyung Park, Si-Kyu Lim, Byoung Chul Park
Summary: Genetic mutations like SNP are common in genetic disorders and cancers, and PCR methods are widely used for SNP detection. The specifically designed PCR platform STexS can efficiently distinguish small amounts of SNP mixed in normal DNA, aiding in targeting potential SNPs or genetically mutated biomarkers in human clinical samples.
SCIENTIFIC REPORTS
(2021)
Article
Chemistry, Analytical
Shuwen Lin, Xiaomei Hu, Jiayi Lin, Shunqin Wang, Jin Xu, Fan Cai, Jiancheng Lin
Summary: This study presents a sensitive pH-responsive point-of-care electrochemical immunoassay for quantitative monitoring of H1N1 influenza virus. The use of Ti3C2-MXene nanosheets enhances detection sensitivity and signal amplification, showing promising potential for point-of-care applications in diagnostics.
Article
Obstetrics & Gynecology
Nicola Vousden, Marian Knight
Summary: Influenza during pregnancy is associated with an increased risk of hospital admission, and there is variability in policies and uptake of immunization globally. Immunization is cost-effective and safe in preventing influenza in pregnant women and their infants.
BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY
(2021)
Article
Infectious Diseases
Victor Au Yeung, Kiran Thapa, William Rawlinson, Andrew Georgiou, Jeffrey J. Post, Kristen Overton
Summary: This study found that the use of RPCR testing in influenza management can improve antibiotic stewardship by reducing antibiotic use and improving oseltamivir initiation in high-risk populations. However, further research is needed to determine other factors that may have influenced hospital length of stay and a cost-benefit analysis should be conducted to determine the financial impact of RPCR testing.
BMC INFECTIOUS DISEASES
(2021)
Article
Biology
Michael Lutz, Jordana Schmierer, Toru Takimoto
Summary: Avian species are the main source of pandemic influenza A viruses that can infect humans. This study found that avian influenza A virus genes, including PA, PB1, and PB2, need to undergo host-adaptive mutations in order to replicate and transmit in humans. It was discovered that the PA gene from the 2009 pH1N1 strain had host-adaptive mutations that enhanced viral replication by increasing translation efficiency. This was achieved through increased cytosolic accumulation of viral mRNA, which depended on the host RNA binding protein GRSF1. Mutations to the GRSF1 binding site and knockdown of GRSF1 reduced viral mRNA accumulation and translation efficiency. These findings reveal a previously unrecognized mechanism by which host-adaptive mutations in PA regulate viral replication and host adaptation.
COMMUNICATIONS BIOLOGY
(2022)
Article
Transplantation
Mandana Namayandeh, Marzieh Jamalidoust, Gholamreza Pouladfar, Maryam Zare, Mazyar Ziyaeyan
Summary: This study investigated the role of coinfection with cytomegalovirus and Epstein-Barr virus in solid-organ transplant recipients and found that it is a strong predictive factor for posttransplant lymphoproliferative disorder. Furthermore, the viral loads of both viruses were found to be correlated with the development of the disorder.
EXPERIMENTAL AND CLINICAL TRANSPLANTATION
(2022)
Article
Infectious Diseases
Maryam Zare, Marzieh Jamalidoust, Gholam R. Pouladfar, Ali Amanati, Maryam Shafaati, Mandana Namayandeh, Mazyar Ziyaeyan
Summary: A 34-year-old female clinical virology assistant was punctured with a contaminated lancet used for sampling from a suspected hand, foot, and mouth disease (HFMD) patient. The transmission occurred through needle injury and resulted in systemic disease. Unusual and unexpected viral transmission should be considered when dealing with samples.
Article
Pediatrics
Gholamreza Pouladfar, Anahita Sanaei Dashti, Mohammad Rahim Kadivar, Maedeh Jafari, Bahman Pourabbas, Marzieh Jamalidoust, Sadaf Asaei
Summary: This study evaluated the accuracy of the WHO criteria and PCR in diagnosing childhood bacterial meningitis. The results showed that both methods had high accuracy and could reduce the over-prescription of antibiotics in febrile children suspected of meningitis.
ARCHIVES OF PEDIATRIC INFECTIOUS DISEASES
(2022)
Article
Medicine, Research & Experimental
Armin Attar, Fatemeh Nouri, Arash Yazdanshenas, Kamran Hessami, Massoud Vosough, Alireza Abdi-Ardekani, Peyman Izadpanah, Mani Ramzi, Javad Kojouri, Gholamreza Pouladfar, Ahmad Monabati
Summary: This study aims to compare the effect of single and double injection of MSCs on LVEF improvement after AMI. The study is conducted as a single-blind, randomized, multicenter trial, with the primary endpoint being the assessment of improvement in LVEF.
Article
Medicine, Research & Experimental
Armin Attar, Ahmad Monabati, Mohammad Montaseri, Massoud Vosough, Seyed Ali Hosseini, Javad Kojouri, Alireza Abdi-Ardekani, Peyman Izadpanah, Negar Azarpira, Gholamreza Pouladfar, Mani Ramzi
Summary: This study aims to evaluate the effect of umbilical cord-derived Wharton's jelly MSCs (WJ-MSCs) transplantation on preventing the development of heart failure (HF) after acute myocardial infarction (AMI). It will enroll 390 patients who will be randomly assigned to receive standard care or a single intracoronary infusion of WJ-MSCs. The primary outcome is the assessment of HF development during long-term follow-up (3 years).
Article
Immunology
Nasrin Aliabadi, Marzieh Jamalidoust, Gholamreza Pouladfar, Atoosa Ziyaeyan, Mazyar Ziyaeyan
Summary: The study demonstrates that Triptolide (TP) shows effective inhibition of HSV-1 infection with low toxicity, providing a new approach for effective treatment of HSV-1 infections.
IMMUNITY INFLAMMATION AND DISEASE
(2022)
Review
Dentistry, Oral Surgery & Medicine
Morteza Banakar, Sedigheh Moayedi, Erfan Shamsoddin, Zahra Vahedi, Mohammad Hasan Banakar, Seyyed Mojtaba Mousavi, Dinesh Rokaya, Kamran Bagheri Lankarani
Summary: Chewing gum can serve as a promising drug carrier for oral health due to its sustained release capability and lower required drug dosage.
INTERNATIONAL JOURNAL OF DENTISTRY
(2022)
Article
Multidisciplinary Sciences
Nasrin Aliabadi, Marzieh Jamalidoust, Gholamreza Pouladfar, Negar Azarpira, Atoosa Ziyaeyan, Mazyar Ziyaeyan
Summary: The study found that Triptolide has the potential to be a viable treatment option for ocular HSV infection in mice, showing effectiveness in reducing disease severity and viral levels.
Article
Pediatrics
Marzieh Davoodi, Gholamreza Pouladfar, Mohammad Rahim Kadivar, Alireza Dehghan, Aida Askarisarvestani, Seyedeh Sedigheh Hamzavi
Summary: This article describes a disease called Multisystem Inflammatory Syndrome in Children (MIS-C), characterized by persistent fever, multiorgan dysfunction, inflammation markers, prior SARS-CoV-2 infection, and specific symptoms. A case of MIS-C in a pediatric patient is presented, where abdominal CT scan showed thickening of the ileum and ileocecal junction, and brain MRI showed cytotoxic lesions of the corpus callosum. Further research is urgently needed to understand this syndrome and improve diagnosis and treatment.
Article
Rehabilitation
Saeed Shahabi, Cody L. McDonald, Maryam Jalali, Kamran Bagheri Lankarani, Hassan Joulaei, Masoud Behzadifar, Parviz Mojgani
Summary: This study explores the common challenges faced by the Iranian prosthetics and orthotics sector and analyzes potential leverage points to improve services using a systems thinking approach. The challenges identified include leadership and governance issues, financing issues, service delivery issues, and human resource issues.
DISABILITY AND REHABILITATION
(2022)
Article
Public, Environmental & Occupational Health
Nasrin Aliabadi, Marzieh Jamaliduost, Gholamreza Pouladfar, Nahid H. H. Marandi, Mazyar Ziyaeyan
Summary: Characterization of SARS-CoV-2 based on evolution and mutations is crucial for tracking viral infections and mutants. This study analyzed the complete sequences of SARS-CoV-2 in Iran to reveal genetic distance and mutation rate among different provinces.
HEALTH SCIENCE REPORTS
(2023)
Review
Dentistry, Oral Surgery & Medicine
Morteza Banakar, K. B. Lankarani, Mohebat Vali, Reza Tabrizi, Erfan Taherifard, Maryam Akbari
Summary: This study conducted a systematic meta-analysis to evaluate the effect of mass media campaigns on oral health knowledge. The results showed that these campaigns have positive effects, especially among the working-age population. However, more initiatives are needed to improve health knowledge among children, and the effects seem to be time-dependent and higher in shorter follow-up periods.
INTERNATIONAL JOURNAL OF DENTAL HYGIENE
(2023)
Review
Multidisciplinary Sciences
Shabnam Shahali, Saeed Shahabi, Manal Etemadi, Maryam Hedayati, Cornelia Anne Barth, Parviz Mojgani, Masoud Behzadifar, Kamran Bagheri Lankarani
Summary: This scoping review investigated the barriers and facilitators to integrating physiotherapy into primary health care. It found that poor knowledge of physicians about physiotherapy, ineffective teamwork, and physiotherapists' time constraints/workload were the most common barriers. Clarifying the role of involved professionals, strengthening teamwork, and improving intra-and inter-professional collaborations were suggested as important measures for facilitating the integration process.
Article
Pediatrics
Najmeh Maharlouei, Arash Khojasteh Zonoozi, Zaynab Noeizad, Atila Erami, Hamidreza Parsa, Zahra Eskandari Kootahi, Sara Raji, Kamran B. Lankarani
Summary: This study investigates the prevalence, clinical characteristics, and outcomes of COVID-19 among neonates in Iran. The incidence of COVID-19 among neonates in Fars Province was found to be 47.5 per 100,000 living births in one year. Most neonates recovered, but there were also cases of mortality, with all deceased neonates having symptoms. Some neonates required admission to the neonatal intensive care unit (NICU).
INTERNATIONAL JOURNAL OF PEDIATRICS
(2023)