Review
Public, Environmental & Occupational Health
Sheikh Taslim Ali, Benjamin J. Cowling
Summary: Influenza is a common respiratory infection that causes significant morbidity and mortality worldwide. Advances in computational resources have led to important developments in influenza surveillance and forecasting, including improving surveillance systems by synthesizing multiple sources of information and developing influenza forecasting as an active field. Further work is ongoing to assimilate surveillance data and relevant driving factors to enhance current situation estimates and forecast future dynamics.
ANNUAL REVIEW OF PUBLIC HEALTH, VOL 42, 2021
(2021)
Article
Infectious Diseases
Min Kang, Xiaohua Tan, Meiyun Ye, Yu Liao, Tie Song, Shixing Tang
Summary: The moving epidemic method (MEM) was used to establish epidemic thresholds for influenza in Guangdong, a subtropical province in China, with virology surveillance data from multiple seasons. The study successfully predicted the epidemic for the 2018/2019 season by adapting subtype-specific thresholds. The MEM proved effective in detecting and monitoring influenza epidemics based on different strains of the virus.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Infectious Diseases
Jason A. Galvis, Chris M. Jones, Joaquin M. Prada, Cesar A. Corzo, Gustavo Machado
Summary: Limited understanding of swine disease transmission dynamics hinders disease prevention and control efforts, making it crucial to develop forecasting systems. Three epidemiological models were compared to predict PEDV outbreaks, with a multi-model approach showing promising results in reducing disease spread and improving pig production systems' resilience.
TRANSBOUNDARY AND EMERGING DISEASES
(2022)
Article
Physics, Fluids & Plasmas
Caries Falco, Alvaro Corral
Summary: This study uses a continuous-time branching process to uncover the finite-time scaling law of the survival probability of outbreaks under power-law-tailed superspreading conditions, and reveals a phase transition phenomenon. The research also demonstrates the counterintuitive hazards posed by this type of superspreading.
Article
Infectious Diseases
Debapriyo Chakraborty, Claire Guinat, Nicola F. Muller, Francois-Xavier Briand, Mathieu Andraud, Axelle Scoizec, Sophie Lebouquin, Eric Niqueux, Audrey Schmitz, Beatrice Grasland, Jean-Luc Guerin, Mathilde C. Paul, Timothee Vergne
Summary: This study analyzed the spatiotemporal dynamics of the highly pathogenic avian influenza epidemic in France in 2016-2017 and assessed the impact of control measures on viral spread. The results showed that large-scale culling of ducks significantly reduced viral spread between regions, while restrictions on duck transport within regions may not completely stop the viral spread.
TRANSBOUNDARY AND EMERGING DISEASES
(2022)
Article
Immunology
Alexandre Lampros, Cheikh Talla, Maryam Diarra, Billo Tall, Samba Sagne, Mamadou Korka Diallo, Boly Diop, Ibrahim Oumar, Ndongo Dia, Amadou Alpha Sall, Mamadou Aliou Barry, Cheikh Loucoubar
Summary: Historically low levels of seasonal influenza circulation were reported during the COVID-19 pandemic in Senegal. Influenza showed year-round circulation with two distinct peaks in the country. Unexpectedly, there was a peak in influenza circulation during May-July 2022, indicating a reciprocal circulation with SARS-CoV-2.
EMERGING INFECTIOUS DISEASES
(2023)
Article
Biology
Pia Ryt-Hansen, Jesper Schak Krog, Solvej Ostergaard Breum, Charlotte Kristiane Hjulsager, Anders Gorm Pedersen, Ramona Trebbien, Lars Erik Larsen
Summary: This paper presents the results of swIAV surveillance in Danish swine from 2011 to 2018, revealing multiple different circulating genotypes of the virus, including novel reassortants with human seasonal IAV gene segments. The phylogenetic analysis showed genetic drift in antigenic sites of the hemagglutinin protein and identified a swine divergent cluster among the viruses studied.
Article
Multidisciplinary Sciences
Diego Casas-Deza, Vanesa Bernal-Monterde, Angel Nicolas Aranda-Alonso, Enrique Montil-Miguel, Ana Belen Julian-Gomara, Laura Letona-Gimenez, Jose M. Arbones-Mainar
Summary: The risk of severe COVID-19 increases with age, with higher incidence in individuals over 80 possibly due to transmission within nursing homes. Case fatality rates were low in younger age groups but increased progressively with age, especially during the first pandemic wave. Older patients had a more severe and rapid progression of SARS-CoV-2 infection, emphasizing the need for targeted prevention measures and prioritization of vaccination in the elderly.
Article
Multidisciplinary Sciences
G. Cencetti, G. Santin, A. Longa, E. Pigani, A. Barrat, C. Cattuto, S. Lehmann, M. Salathe, B. Lepri
Summary: Digital contact tracing is increasingly recognized as a tool to control infectious disease outbreaks, especially during the COVID-19 pandemic. The authors present a modeling framework based on high-resolution contact data to analyze the impact of digital contact tracing apps. Results suggest that isolation and tracing can help control re-emerging outbreaks under specific conditions.
NATURE COMMUNICATIONS
(2021)
Article
Multidisciplinary Sciences
Shiva Moein, Niloofar Nickaeen, Amir Roointan, Niloofar Borhani, Zarifeh Heidary, Shaghayegh Haghjooy Javanmard, Jafar Ghaisari, Yousof Gheisari
Summary: The multifaceted destructions caused by COVID-19 have been compared to World War II, creating ambiguity about the duration and spread of the pandemic. Governments, healthcare systems, and economic sectors are crucial to estimate the future of this disaster. While many investigators have used mathematical approaches like the SIR model to predict the outbreak of COVID-19, these models have limitations in accurately forecasting the long-term spread and pattern of the epidemic. More sophisticated modeling strategies and detailed knowledge of the disease are needed to predict the pandemic more accurately.
SCIENTIFIC REPORTS
(2021)
Article
Multidisciplinary Sciences
Baltazar Espinoza, Madhav Marathe, Samarth Swarup, Mugdha Thakur
Summary: Infections caused by non-symptomatic individuals can either increase or reduce the final epidemic size depending on individuals' risk misperception. The impact of non-symptomatic infections is modulated by symptomatic individuals' behavior under behavioral response. There exists an optimal planning horizon that minimizes the final epidemic size.
SCIENTIFIC REPORTS
(2021)
Article
Biochemical Research Methods
Daipeng Chen, Yuyi Xue, Yanni Xiao
Summary: This study introduces a strategy to restrict population travel to prevent the spatial spread of infectious diseases and proposes a model for describing the spread of infectious diseases. The focus of the study is on determining when travel restrictions can be lifted and providing a new travel flux triggering scheme.
PLOS COMPUTATIONAL BIOLOGY
(2021)
Article
Immunology
Steven Van Borm, Simon Dellicour, Mieke Steensels, Virginie Roupie, Frank Vandenbussche, Elisabeth Mathijs, Aline Vilain, Michele Driesen, Marc Dispas, Andy W. Delcloo, Philippe Lemey, Ingeborg Mertens, Marius Gilbert, Benedicte Lambrecht, Thierry van den Berg
Summary: Phylogeographic and epidemiologic analyses were integrated to investigate the dynamics of a low pathogenicity avian influenza epidemic in Belgium in 2019. The study revealed a dominant northeast to southwest dispersal direction and a long-distance dispersal event associated with live animal transportation between farms. The spatial and temporal patterns of the epidemic were strongly correlated with transport, social contacts, and the phylogeographic analysis.
EMERGING INFECTIOUS DISEASES
(2023)
Article
Immunology
Pedro Plans Rubio, Anna M. Jambrina, Pilar Rius, Gloria Carmona, Manel Rabanal, Montse Girones
Summary: Influenza surveillance and vaccination are crucial for preventing and controlling influenza epidemics. A study in Catalonia, Spain, assessed influenza surveillance and vaccination data from sentinel pharmacies during the 2021-2022 influenza season. The study found no influenza epidemic during this season, likely due to influenza vaccination and COVID-19 prevention measures.
Article
Multidisciplinary Sciences
Harald S. Vohringer, Theo Sanderson, Matthew Sinnott, Nicola De Maio, Thuy Nguyen, Richard Goater, Frank Schwach, Ian Harrison, Joel HeHowells, Cristina Ariani, Sonia Goncalves, David K. Jackson, Ian Johnstone, Alexander W. Jung, Callum Saint, John Sillitoe, Maria Suciu, Nick Goldman, Jasmine Panovska-Griffiths, Ewan Birney, Erik Volz, Sebastian Funk, Dominic Kwiatkowski, Meera Chand, Inigo Martincorena, Jeffrey C. Barrett, Moritz Gerstung
Summary: The study analyzed the dynamics of different lineages in English local authorities using real-time genomic data. The findings showed significant fluctuations in transmissibility and proportions of different variants over time, with Delta variant rapidly increasing in early summer 2021.
Article
Biotechnology & Applied Microbiology
Lisa D. MacDonald, Alecia MacKay, Valarmathy Kaliaperumal, Genevieve Weir, Andrea Penwell, Rajkannan Rajagopalan, Joanne M. Langley, Scott Halperin, Marc Mansour, Marianne M. Stanford
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2018)
Article
Multidisciplinary Sciences
Dena Schanzer, Tony Antoniou, Jeffrey Kwong, Karen Timmerman, Ping Yan
Article
Immunology
A. Cattapan, K. Browne, D. M. Halperin, A. Di Castri, P. Fullsack, J. Graham, J. M. Langley, B. A. Taylor, S. A. McNeil, S. A. Halperin
Article
Immunology
Shalini Desai, Dena L. Schanzer, Anada Silva, Jenny Rotondo, Susan G. Squires
Article
Pediatrics
Matthew Jalink, Joanne M. Langley
Summary: There is substantial variation in qualifications for RSV prevention with palivizumab among Canadian provinces and territories, and none of them strictly adhere to the guidelines set by the Canadian Paediatric Society. The differences in subnational policies may be due to factors such as resource availability, interpretation of efficacy evidence, epidemiological variations, local pressures, or advocacy efforts.
PAEDIATRICS & CHILD HEALTH
(2021)
Article
Multidisciplinary Sciences
Maria Hartley, Christy G. Woolcott, Joanne M. Langley, Mary M. Brown, Jillian Ashley-Martin, Stefan Kuhle
SCIENTIFIC REPORTS
(2020)
Article
Biotechnology & Applied Microbiology
Heather L. Torrey, Valarmathy Kaliaperumal, Yogesh Bramhecha, Genevieve M. Weir, Ann R. Falsey, Edward E. Walsh, Joanne M. Langley, Bert Schepens, Xavier Saelens, Marianne M. Stanford
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2020)
Article
Immunology
Joanne Langley, Elodie Pastural, Scott Halperin, Shelly McNeil, May ElSherif, Donna MacKinnon-Cameron, Lingyun Ye, Cecile Grange, Valerie Thibodeau, Jean-Francois Cailhier, Rejean Lapointe, Janet McElhaney, Luis Martin, Marilene Bolduc, Marie-Eve Laliberte-Gagne, Denis Leclerc, Pierre Savard
Review
Immunology
Melissa Rioux, Mara McNeil, Magen E. Francis, Nicholas Dawe, Mary Foley, Joanne M. Langley, Alyson A. Kelvin
Article
Public, Environmental & Occupational Health
Kieran J. Moore, David Greencorn, Nadine Smith, Joanne M. Langley, Ketan Kulkarni
Summary: This study found that mechanical complications of CVCs are common and significant in the pediatric population, with the highest risk seen in non-tunneled lines. The authors suggest that CVC-associated mechanical complications should be routinely reported as a patient safety outcome.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2022)
Article
Pediatrics
Jennifer B. Frazer, Dafydd A. Davies, Joanne M. Langley
Summary: This report presents a case of a newborn with a Staphylococcus aureus infection of a branchial cleft anomaly (BCA) and reviews the characteristics and frequency of infection of this congenital anomaly over 18 years at our center. It is found that 6% of patients presented as neonates and 42% of BCAs became infected.
JOURNAL OF PEDIATRIC SURGERY CASE REPORTS
(2022)
Article
Biotechnology & Applied Microbiology
Terra A. Manca, Manish Sadarangani, Scott A. Halperin, Joanne M. Langley, Elisabeth McClymont, Shannon E. MacDonald, Karina A. Top
Summary: Exclusion of pregnant and breastfeeding women from COVID-19 vaccine trials has led to knowledge gaps, vaccine hesitancy, and misinformation. Inclusion of these populations in trials should be prioritized and regulatory authorities can play a crucial role.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2022)
Article
Public, Environmental & Occupational Health
David J. Greencorn, Stefan Kuhle, Lingyun Ye, Kieran J. Moore, Ketan P. Kulkarni, Joanne M. Langley
Summary: Risk factors for mechanical complications in children with PICCs have been identified, which can improve best practices for PICC insertion and care.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2023)
Article
Immunology
Zourab Bebia, Osvaldo Reyes, Robert Jeanfreau, Anu Kantele, Ruth Graciela De Leon, Marta Garcia Sanchez, Peyman Banooni, Glenn J. Gardener, Jose Luis Bartha Rasero, Maria Begona Encinas Pardilla, Joanne M. Langley, Claudio Maanon Di Leo, Elisabeth Botelho-Nevers, Jim Buttery, Helene Laurichesse, Shabir A. Madhi, Adrian Martin Garcia, Thorsten Stanley, Tiphaine Barjat, Rebecca Griffith, Maria Mercedes Castrejon-Alba, Magali de Heusch, Ilse Dieussaert, Melanie Hercor, Patricia Lese, Hui Qian, Antonella N. Tullio, Ouzama Henry
Summary: Maternal vaccination with RSVPreF3 during late pregnancy has an acceptable safety risk profile and induces robust RSV-specific immune responses with successful antibody transfer to newborns.
JOURNAL OF INFECTIOUS DISEASES
(2023)
Article
Infectious Diseases
Janet A. Englund, Rachel A. Cohen, Veronique Bianco, Joseph B. Domachowske, Joanne M. Langley, Shabir A. Madhi, Khalequ Zaman, Agustin Bueso, Ana Ceballos, Luis Cousin, Sanjay Gandhi, Olivier Gruselle, Lisa Jose, Nicola P. Klein, Anthonet Koen, Thanyawee Puthanakit, Meng Shi, Peter Silas, Auchara Tangsathapornpong, Jamaree Teeratakulpisarn, Timo Vesikari, Gerco Haars, Amanda Leach, Sonia K. Stoszek, Ilse Dieussaert
Summary: Respiratory syncytial virus (RSV) causes respiratory illnesses ranging from common cold to moderate and severe lung disease. Symptoms and methods used to identify/track RSV disease are not always the same in different settings. Three definitions of RSV disease were compared with the World Health Organization (WHO) recommendation in 2015. A universal definition of RSV disease and severity is needed for effective treatment and prevention measures.
JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY
(2023)