Novel Rho/MRTF/SRF Inhibitors Block Matrix-stiffness and TGF-β–Induced Fibrogenesis in Human Colonic Myofibroblasts
出版年份 2013 全文链接
标题
Novel Rho/MRTF/SRF Inhibitors Block Matrix-stiffness and TGF-β–Induced Fibrogenesis in Human Colonic Myofibroblasts
作者
关键词
-
出版物
INFLAMMATORY BOWEL DISEASES
Volume 20, Issue 1, Pages 154-165
出版商
Oxford University Press (OUP)
发表日期
2013-11-27
DOI
10.1097/01.mib.0000437615.98881.31
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Narrative Review: Fibrotic Diseases: Cellular and Molecular Mechanisms and Novel Therapies
- (2013) Joel Rosenbloom ANNALS OF INTERNAL MEDICINE
- Optimization of novel nipecotic bis(amide) inhibitors of the Rho/MKL1/SRF transcriptional pathway as potential anti-metastasis agents
- (2013) Jessica L. Bell et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Matrix Stiffness Corresponding to Strictured Bowel Induces a Fibrogenic Response in Human Colonic Fibroblasts
- (2013) Laura A. Johnson et al. INFLAMMATORY BOWEL DISEASES
- Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis
- (2013) Yong Zhou et al. JOURNAL OF CLINICAL INVESTIGATION
- Matrix Stiffness–Induced Myofibroblast Differentiation Is Mediated by Intrinsic Mechanotransduction
- (2012) Xiangwei Huang et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- CARD-024, a vitamin D analog, attenuates the pro-fibrotic response to substrate stiffness in colonic myofibroblasts
- (2012) Laura A. Johnson et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Burden of illness in idiopathic pulmonary fibrosis
- (2012) Harold R. Collard et al. JOURNAL OF MEDICAL ECONOMICS
- Role of RhoA and its effectors ROCK and mDia1 in the modulation of deformation-induced FAK, ERK, p38, and MLC motogenic signals in human Caco-2 intestinal epithelial cells
- (2011) Lakshmi S. Chaturvedi et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Themes in fibrosis and gastrointestinal inflammation
- (2011) Claudio Fiocchi et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Delayed stress fiber formation mediates pulmonary myofibroblast differentiation in response to TGF-β
- (2011) Nathan Sandbo et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Enhancement of corneal endothelium wound healing by Rho-associated kinase (ROCK) inhibitor eye drops
- (2011) N. Okumura et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- More than a feeling: discovering, understanding, and influencing mechanosensing pathways
- (2011) Andrew W Holle et al. CURRENT OPINION IN BIOTECHNOLOGY
- Spironolactone and Colitis: Increased Mortality in Rodents and in Humans
- (2011) Laura A. Johnson et al. INFLAMMATORY BOWEL DISEASES
- Intestinal fibrosis is reduced by early elimination of inflammation in a mouse model of IBD: Impact of a “Top-Down” approach to intestinal fibrosis in mice
- (2011) Laura A. Johnson et al. INFLAMMATORY BOWEL DISEASES
- Myocardin-related Transcription Factor-A Complexes Activate Type I Collagen Expression in Lung Fibroblasts
- (2011) Larry L. Luchsinger et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Wound Contraction Is Attenuated by Fasudil Inhibition of Rho-Associated Kinase
- (2011) Jennifer E. Bond et al. PLASTIC AND RECONSTRUCTIVE SURGERY
- Myocardin-Related Transcription Factor-A Controls Myofibroblast Activation and Fibrosis in Response to Myocardial Infarction
- (2010) Eric M. Small et al. CIRCULATION RESEARCH
- Rho-kinase/ROCK: A key regulator of the cytoskeleton and cell polarity
- (2010) Mutsuki Amano et al. Cytoskeleton
- Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression
- (2010) Fei Liu et al. JOURNAL OF CELL BIOLOGY
- Linking actin dynamics and gene transcription to drive cellular motile functions
- (2010) Eric N. Olson et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Critical Role of Serum Response Factor in Pulmonary Myofibroblast Differentiation Induced by TGF-β
- (2009) Nathan Sandbo et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Design, synthesis and prostate cancer cell-based studies of analogs of the Rho/MKL1 transcriptional pathway inhibitor, CCG-1423
- (2009) Chris R. Evelyn et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion
- (2009) Shuh Narumiya et al. CANCER AND METASTASIS REVIEWS
- Rho-kinase inhibitors as therapeutics: from pan inhibition to isoform selectivity
- (2009) C. Hahmann et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The myofibroblast: Paradigm for a mechanically active cell
- (2009) Boris Hinz JOURNAL OF BIOMECHANICS
- Non-muscle myosin II takes centre stage in cell adhesion and migration
- (2009) Miguel Vicente-Manzanares et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Transforming growth factor-β1 induces intestinal myofibroblast differentiation and modulates their migration
- (2009) Julia Brenmoehl et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Tissue stiffness, latent TGF-β1 Activation, and mechanical signal transduction: Implications for the pathogenesis and treatment of fibrosis
- (2009) Boris Hinz Current Rheumatology Reports
- Specific signals involved in the long-term maintenance of radiation-induced fibrogenic differentiation: a role for CCN2 and low concentration of TGF-β1
- (2008) Valérie Haydont et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Mechanisms of Fibrogenesis
- (2008) Tatiana Kisseleva et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Growth control by intracellular tension and extracellular stiffness
- (2008) Richard K. Assoian et al. TRENDS IN CELL BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now