T300A Variant of Autophagy ATG16L1 Gene is Associated with Decreased Antigen Sampling and Processing by Dendritic Cells in Pediatric Crohnʼs Disease

Crohn diseaseATG16L1polymorphism increases susceptibility to infection withHelicobacter pyloriin humans

(2012) Deepa Raju et al.   Autophagy

Hypothesis-free analysis of ATG16L1 demonstrates gene-wide extent of association with Crohn's disease susceptibility: Table 1

(2012) Johan Van Limbergen et al.   GUT

Impaired autophagy leads to abnormal dendritic cell–epithelial cell interactions

(2012) Caterina Strisciuglio et al.   Journal of Crohns & Colitis

Interaction between FIP200 and ATG16L1 distinguishes ULK1 complex–dependent and –independent autophagy

(2012) Noor Gammoh et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Inflammatory Bowel Disease: An Update on the Fundamental Biology and Clinical Management

(2011) Richard Blumberg et al.   GASTROENTEROLOGY

Functional consequences of mutations in the autophagy genes in the pathogenesis of Crohnʼs disease

(2011) Oliver Brain et al.   INFLAMMATORY BOWEL DISEASES

Virus-Plus-Susceptibility Gene Interaction Determines Crohn's Disease Gene Atg16L1 Phenotypes in Intestine

(2010) Ken Cadwell et al.   CELL

Autophagy in infection

(2010) Vojo Deretic   CURRENT OPINION IN CELL BIOLOGY

E-Cadherin Marks a Subset of Inflammatory Dendritic Cells that Promote T Cell-Mediated Colitis

(2010) Karima R.R. Siddiqui et al.   IMMUNITY

Epidemiology of pediatric inflammatory bowel disease: A systematic review of international trends

(2010) Eric I. Benchimol et al.   INFLAMMATORY BOWEL DISEASES

Association of ATG16L1 and IRGM genes polymorphisms with inflammatory bowel disease: a meta-analysis approach

(2009) R J Palomino-Morales et al.   GENES AND IMMUNITY

Differential Involvement of Atg16L1 in Crohn Disease and Canonical Autophagy

(2009) Naonobu Fujita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

(2009) Rachel Cooney et al.   NATURE MEDICINE

Dynamics and diversity in autophagy mechanisms: lessons from yeast

(2009) Hitoshi Nakatogawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ATP-induced autophagy is associated with rapid killing of intracellular mycobacteria within human monocytes/macrophages

(2008) Debasis Biswas et al.   BMC IMMUNOLOGY

Definition of Phenotypic Characteristics of Childhood-Onset Inflammatory Bowel Disease

(2008) Johan Van Limbergen et al.   GASTROENTEROLOGY

Contributions of IBD5, IL23R, ATG16L1, and NOD2 to Crohnʼs disease risk in a population-based case-control study: Evidence of gene–gene interactions

(2008) Toshihiko Okazaki et al.   INFLAMMATORY BOWEL DISEASES

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production

(2008) Tatsuya Saitoh et al.   NATURE

Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease

(2008) Steven A McCarroll et al.   NATURE GENETICS