Epigenetics: Concepts and relevance to IBD pathogenesis

Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification

(2011) Minjia Tan et al.   CELL

Aberrations of EZH2 in Cancer

(2011) A. Chase et al.   CLINICAL CANCER RESEARCH

Revealing histone variant induced changes via quantitative proteomics

(2011) Anna M. Arnaudo et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Epigenetics and B-cell lymphoma

(2011) Rita Shaknovich et al.   CURRENT OPINION IN HEMATOLOGY

Regulation of mammalian DNA methyltransferases: a route to new mechanisms

(2011) Hélène Denis et al.   EMBO REPORTS

OPERating ON Chromatin, a Colorful Language where Context Matters

(2011) Kathryn E. Gardner et al.   JOURNAL OF MOLECULAR BIOLOGY

When Signaling Kinases Meet Histones and Histone Modifiers in the Nucleus

(2011) Sung Hee Baek   MOLECULAR CELL

Genetics and pathogenesis of inflammatory bowel disease

(2011) Bernard Khor et al.   NATURE

Non-coding RNAs in human disease

(2011) Manel Esteller   NATURE REVIEWS GENETICS

Genome-scale epigenetic reprogramming during epithelial-to-mesenchymal transition

(2011) Oliver G McDonald et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ulcerative Colitis

(2011) Silvio Danese et al.   NEW ENGLAND JOURNAL OF MEDICINE

Histone modification: cause or cog?

(2011) Steven Henikoff et al.   TRENDS IN GENETICS

Histone deacetylases as regulators of inflammation and immunity

(2011) Melanie R. Shakespear et al.   TRENDS IN IMMUNOLOGY

Inflammatory Bowel Disease

(2010) Arthur Kaser et al.   Annual Review of Immunology

Antifibrotic activity of an inhibitor of histone deacetylases in DOCA-salt hypertensive rats

(2010) Abishek Iyer et al.   BRITISH JOURNAL OF PHARMACOLOGY

Anti-inflammatory Agents: Present and Future

(2010) Charles A. Dinarello   CELL

Selective Transcription in Response to an Inflammatory Stimulus

(2010) Stephen T. Smale   CELL

The Blessings and Curses of Intestinal Inflammation

(2010) Sebastian E. Winter et al.   Cell Host & Microbe

Identification of disease-associated DNA methylation in intestinal tissues from patients with inflammatory bowel disease

(2010) Z Lin et al.   CLINICAL GENETICS

The role of deubiquitinating enzymes in chromatin regulation

(2010) Boyko S. Atanassov et al.   FEBS LETTERS

Histone arginine methylation

(2010) Alessandra Di Lorenzo et al.   FEBS LETTERS

Topical agents for idiopathic distal colitis and proctitis

(2010) Ian Craig Lawrance   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

miRNAs in human cancer

(2010) Thalia A Farazi et al.   JOURNAL OF PATHOLOGY

Repression of IP-10 by Interactions between Histone Deacetylation and Hypermethylation in Idiopathic Pulmonary Fibrosis

(2010) W. R. Coward et al.   MOLECULAR AND CELLULAR BIOLOGY

Polycomb Group Protein Displacement and Gene Activation through MSK-Dependent H3K27me3S28 Phosphorylation

(2010) Simmi Suman Gehani et al.   MOLECULAR CELL

Epigenetics as a unifying principle in the aetiology of complex traits and diseases

(2010) Arturas Petronis   NATURE

Epigenetic modifications and human disease

(2010) Anna Portela et al.   NATURE BIOTECHNOLOGY

Deregulation of H3K27 methylation in cancer

(2010) Eva Martinez-Garcia et al.   NATURE GENETICS

Methylation determines fibroblast activation and fibrogenesis in the kidney

(2010) Wibke Bechtel et al.   NATURE MEDICINE

Chromatin structure and the inheritance of epigenetic information

(2010) Raphaël Margueron et al.   NATURE REVIEWS GENETICS

Histone variants — ancient wrap artists of the epigenome

(2010) Paul B. Talbert et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Molecular Signals of Epigenetic States

(2010) Roberto Bonasio et al.   SCIENCE

Histone demethylases in development and disease

(2010) Marianne Terndrup Pedersen et al.   TRENDS IN CELL BIOLOGY

Targeting DNA methylation for epigenetic therapy

(2010) Xiaojing Yang et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Global Levels of Histone Modifications Predict Prognosis in Different Cancers

(2009) David B. Seligson et al.   AMERICAN JOURNAL OF PATHOLOGY

Epigenetic mechanisms of regulation of Foxp3 expression

(2009) G. Lal et al.   BLOOD

Control of Inducible Gene Expression by Signal-Dependent Transcriptional Elongation

(2009) Diana C. Hargreaves et al.   CELL

A Unifying Model for the Selective Regulation of Inducible Transcription by CpG Islands and Nucleosome Remodeling

(2009) Vladimir R. Ramirez-Carrozzi et al.   CELL

Promoter methylation of protease-activated receptor (PAR2) is associated with severe clinical phenotypes of ulcerative colitis (UC)

(2009) Tomomitsu Tahara et al.   CLINICAL AND EXPERIMENTAL MEDICINE

Histone Deacetylase Inhibitors In Inflammatory Disease

(2009) Maria Halili et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Jmjd3 contributes to the control of gene expression in LPS-activated macrophages

(2009) Francesca De Santa et al.   EMBO JOURNAL

Suberoylanilide hydroxamic acid: a potential epigenetic therapeutic agent for lung fibrosis?

(2009) Z. Wang et al.   EUROPEAN RESPIRATORY JOURNAL

Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways

(2009) S. Ghisletti et al.   GENES & DEVELOPMENT

Chronic administration of valproic acid inhibits activation of mouse hepatic stellate cellsin vitroandin vivo

(2009) Inge Mannaerts et al.   HEPATOLOGY

Effect of MDR1 gene promoter methylation in patients with ulcerative colitis

(2009) Tahara   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

The NF-κB Factor RelB and Histone H3 Lysine Methyltransferase G9a Directly Interact to Generate Epigenetic Silencing in Endotoxin Tolerance

(2009) Xiaoping Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic and Selective Nucleosome Repositioning during Endotoxin Tolerance

(2009) Mohamed El Gazzar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chromatin-Specific Remodeling by HMGB1 and Linker Histone H1 Silences Proinflammatory Genes during Endotoxin Tolerance

(2009) M. E. Gazzar et al.   MOLECULAR AND CELLULAR BIOLOGY

Progression through the RNA Polymerase II CTD Cycle

(2009) Stephen Buratowski   MOLECULAR CELL

Defining mechanisms that regulate RNA polymerase II transcription in vivo

(2009) Nicholas J. Fuda et al.   NATURE

The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores

(2009) Rafael A Irizarry et al.   NATURE GENETICS

Protein methyltransferases as a target class for drug discovery

(2009) Robert A. Copeland et al.   NATURE REVIEWS DRUG DISCOVERY

PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing

(2009) Quan Zhao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain

(2009) S. Kriaucionis et al.   SCIENCE

Endotoxin tolerance: new mechanisms, molecules and clinical significance

(2009) Subhra K. Biswas et al.   TRENDS IN IMMUNOLOGY

Thy-1 Promoter Hypermethylation

(2008) Yan Y. Sanders et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Histones: Annotating Chromatin

(2008) Eric I. Campos et al.   Annual Review of Genetics

At the crossroads of T helper lineage commitment—Epigenetics points the way

(2008) Peter C.J. Janson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Gene-specific control of the TLR-induced inflammatory response

(2008) Simmie L. Foster et al.   CLINICAL IMMUNOLOGY

MicroRNAs Are Differentially Expressed in Ulcerative Colitis and Alter Expression of Macrophage Inflammatory Peptide-2α

(2008) Feng Wu et al.   GASTROENTEROLOGY

Histone Ubiquitination: Triggering Gene Activity

(2008) Vikki M. Weake et al.   MOLECULAR CELL

Lysine Acetylation: Codified Crosstalk with Other Posttranslational Modifications

(2008) Xiang-Jiao Yang et al.   MOLECULAR CELL

Chemical probes for histone-modifying enzymes

(2008) Philip A Cole   Nature Chemical Biology

Combinatorial patterns of histone acetylations and methylations in the human genome

(2008) Zhibin Wang et al.   NATURE GENETICS

Trichostatin A, a histone deacetylase inhibitor, suppresses synovial inflammation and subsequent cartilage destruction in a collagen antibody-induced arthritis mouse model

(2008) Y. Nasu et al.   OSTEOARTHRITIS AND CARTILAGE