SHPS-1 and a synthetic peptide representing its ITIM inhibit the MyD88, but not TRIF, pathway of TLR signaling through activation of SHP and PI3K in THP-1 cells

Synthetic peptides containing ITIM-like sequences of IREM-1 inhibit BAFF-mediated regulation of interleukin-8 expression and phagocytosis through SHP-1 and/or PI3K

(2011) Sang-Min Lee et al.   IMMUNOLOGY

CD300F Blocks Both MyD88 and TRIF-Mediated TLR Signaling through Activation of Src Homology Region 2 Domain-Containing Phosphatase 1

(2011) S.-M. Lee et al.   JOURNAL OF IMMUNOLOGY

Immune receptor expressed on myeloid cells 1 (IREM-1) inhibits B cell activation factor (BAFF)-mediated inflammatory regulation of THP-1 cells through modulation of the activities of extracellular regulated kinase (ERK)

(2010) S.-M. Lee et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Pattern Recognition via the Toll-Like Receptor System in the Human Female Genital Tract

(2010) Kaei Nasu et al.   MEDIATORS OF INFLAMMATION

Suppression of the TRIF-dependent signaling pathway of Toll-like receptors by luteolin

(2009) Jun Kyung Lee et al.   BIOCHEMICAL PHARMACOLOGY

MyD88 Adapter-like (Mal)/TIRAP Interaction with TRAF6 Is Critical for TLR2- and TLR4-mediated NF-κB Proinflammatory Responses

(2009) Brett Verstak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production

(2009) Mikyoung Chang et al.   NATURE IMMUNOLOGY

Regulation of Immune Responses by the Activating and Inhibitory Myeloid-Associate Immunoglobuline-Like Receptors (MAIR) (CD300)

(2009) Akira Shibuya et al.   Immune Network

SHPS-1/SIRP1α contributes to interleukin-6 signalling

(2008) Radoslaw M. Sobota et al.   CELLULAR SIGNALLING

Negative regulation by SHPS-1 of Toll-like receptor-dependent proinflammatory cytokine production in macrophages

(2008) Atsuko Miyake et al.   GENES TO CELLS

Phosphatase SHP-1 promotes TLR- and RIG-I-activated production of type I interferon by inhibiting the kinase IRAK1

(2008) Huazhang An et al.   NATURE IMMUNOLOGY

Leishmania-Induced IRAK-1 Inactivation Is Mediated by SHP-1 Interacting with an Evolutionarily Conserved KTIM Motif

(2008) Issa Abu-Dayyeh et al.   PLoS Neglected Tropical Diseases